This paper describes a comprehensive seismic microzonation investigation carried out for the North-West New Territories region of Hong Kong. Over 3000 boreholes and in-situ and laboratory tests were used to characterize soil properties and develop shear wave velocity profiles for the area. One-dimensional site response analyses were performed on 27 soil profiles to determine how the soils would respond to different levels of earthquake ground motions. The results were used to classify the sites into four groups based on their period and develop corresponding design response spectra. Microzonation maps showing variations in average shear wave velocity and natural period in the study area were generated to delineate differences in seismic hazards spatially.