While discoveries about viruses, which carry the largest genetic information code in nature, have continued unabated for more than a century, viruses are constantly affecting the global biological balance. The main characteristics that make viruses important in this balance include epidemics and mass deaths, the risks of being used as biological weapons, and the continued lack of an effective vaccine or specific treatment for many viruses. However, viruses also offer incredible opportunities for the scientific world, due to biotechnological innovations that have gained momentum in recent years. The detection of viruses is of urgent importance for the early detection of pandemics and epidemics. In this chapter, we discuss the classification of viruses, the effects of viruses on biological balance of our planet, the importance of detecting viruses that have the potential to be used as biological weapons or that carry epidemic or pandemic risks, and the characteristics of such viruses. Dr. Hari Krishna Shriwas | Dr. Sandeep Singh Tiwari "Virus and its Identification in Modern Era" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-7 , December 2022, URL: https://www.ijtsrd.com/papers/ijtsrd52363.pdf Paper URL: https://www.ijtsrd.com/medicine/ayurvedic/52363/virus-and-its-identification-in-modern-era/dr-hari-krishna-shriwas
potassium, chloride, bicarbonate, blood urea nitrogen (BUN), magnesium, creatinine, glucose, and sometimes calcium. Tests that focus on cholesterol levels can determine LDL and HDL cholesterol levels, as well as triglyceride levels.[6]
International Journal of Virology Studies & Research (IJVSR) ISSN:2330-0027 is a comprehensive, peer reviewed journal devoted to Virology Studies & Research. IJVSR, published by SciDoc is an open access journal that includes high quality papers, which covers all major areas of Virology Studies & Research. SciDoc with its Open Access publication model spreads all the day-to-day developments and research to readers around the world.
International Journal of Virology Studies & Research (IJVSR) ISSN:2330-0027 is a comprehensive, peer reviewed journal devoted to Virology Studies & Research. IJVSR, published by SciDoc is an open access journal that includes high quality papers, which covers all major areas of Virology Studies & Research. SciDoc with its Open Access publication model spreads all the day-to-day developments and research to readers around the world.
IJVSR aims to publish all the latest and outstanding research articles, reviews and letters in all areas of Virology. It contains a series of timely, in-depth written articles by scholars & researchers in the field, covering a wide range of the integration of multidimensional challenges of research of Virology
http://scidoc.org/IJVSR.php
International Journal of Virology Studies & Research (IJVSR) ISSN:2330-0027 is a comprehensive, peer reviewed journal devoted to Virology Studies & Research. IJVSR, published by SciDoc is an open access journal that includes high quality papers, which covers all major areas of Virology Studies & Research. SciDoc with its Open Access publication model spreads all the day-to-day developments and research to readers around the world.
IJVSR aims to publish all the latest and outstanding research articles, reviews and letters in all areas of Virology. It contains a series of timely, in-depth written articles by scholars & researchers in the field, covering a wide range of the integration of multidimensional challenges of research of Virology
The SARS2 coronavirus, COVID19 and our futureSayantanBose13
Webinar presented by Sayantan Bose, PhD
Autonomous Therapeutics, Inc./Harvard Medical School
At the Department of Microbiology, Career College, Bhopal, India
ABSTRACT- Human immunodeficiency virus (HIV) is a major contributor to the global burden of the disease, opportunistic infections, and tumors follow. HIV also directly attacks the immune system and affects certain body’s system (like Central Nervous System, Respiratory and Cardiovascular Systems, Digestive System etc). HIV transmission is complex and depends on the number of behavioral and biological co-factors. The hallmark of HIV infection is the progressive depletion of CD4 helper T cells because of reduced production and increased destruction. Although the typical HIV infected patient shows a sustained CD4 cell increase, a remarkable number of subjects never achieve normal ranges of CD4. HIV infection is also characterized by a marked increase in immune activation, which includes both the adaptive and innate immune systems and abnormalities in coagulation. Extraordinary efforts in the fields of clinical, pharmacology, and biology care have contributed to progressively turn HIV infection from an unavoidably fatal condition into a chronic manageable disease, at least in the countries where HIV infected people have full access to the potent anti-retroviral (ARV) drug combinations that permit a marked and sustained control of viral replication. Although their pathogenesis is still under discussed, they are likely to originate from immune dysfunction associated with HIV infection and chronic inflammation. The last consideration regards the dis-homogenous pattern of HIV disease worldwide. Key-words- Human immunodeficiency virus (HIV), simian immunodeficiency viruses (SIV), Antiretroviral (ARV) therapy, Acquired immunodeficiency syndrome (AIDS), Cell mediated immunity (CMI), Anti-retroviral agents
potassium, chloride, bicarbonate, blood urea nitrogen (BUN), magnesium, creatinine, glucose, and sometimes calcium. Tests that focus on cholesterol levels can determine LDL and HDL cholesterol levels, as well as triglyceride levels.[6]
potassium, chloride, bicarbonate, blood urea nitrogen (BUN), magnesium, creatinine, glucose, and sometimes calcium. Tests that focus on cholesterol levels can determine LDL and HDL cholesterol levels, as well as triglyceride levels.[6]
International Journal of Virology Studies & Research (IJVSR) ISSN:2330-0027 is a comprehensive, peer reviewed journal devoted to Virology Studies & Research. IJVSR, published by SciDoc is an open access journal that includes high quality papers, which covers all major areas of Virology Studies & Research. SciDoc with its Open Access publication model spreads all the day-to-day developments and research to readers around the world.
International Journal of Virology Studies & Research (IJVSR) ISSN:2330-0027 is a comprehensive, peer reviewed journal devoted to Virology Studies & Research. IJVSR, published by SciDoc is an open access journal that includes high quality papers, which covers all major areas of Virology Studies & Research. SciDoc with its Open Access publication model spreads all the day-to-day developments and research to readers around the world.
IJVSR aims to publish all the latest and outstanding research articles, reviews and letters in all areas of Virology. It contains a series of timely, in-depth written articles by scholars & researchers in the field, covering a wide range of the integration of multidimensional challenges of research of Virology
http://scidoc.org/IJVSR.php
International Journal of Virology Studies & Research (IJVSR) ISSN:2330-0027 is a comprehensive, peer reviewed journal devoted to Virology Studies & Research. IJVSR, published by SciDoc is an open access journal that includes high quality papers, which covers all major areas of Virology Studies & Research. SciDoc with its Open Access publication model spreads all the day-to-day developments and research to readers around the world.
IJVSR aims to publish all the latest and outstanding research articles, reviews and letters in all areas of Virology. It contains a series of timely, in-depth written articles by scholars & researchers in the field, covering a wide range of the integration of multidimensional challenges of research of Virology
The SARS2 coronavirus, COVID19 and our futureSayantanBose13
Webinar presented by Sayantan Bose, PhD
Autonomous Therapeutics, Inc./Harvard Medical School
At the Department of Microbiology, Career College, Bhopal, India
ABSTRACT- Human immunodeficiency virus (HIV) is a major contributor to the global burden of the disease, opportunistic infections, and tumors follow. HIV also directly attacks the immune system and affects certain body’s system (like Central Nervous System, Respiratory and Cardiovascular Systems, Digestive System etc). HIV transmission is complex and depends on the number of behavioral and biological co-factors. The hallmark of HIV infection is the progressive depletion of CD4 helper T cells because of reduced production and increased destruction. Although the typical HIV infected patient shows a sustained CD4 cell increase, a remarkable number of subjects never achieve normal ranges of CD4. HIV infection is also characterized by a marked increase in immune activation, which includes both the adaptive and innate immune systems and abnormalities in coagulation. Extraordinary efforts in the fields of clinical, pharmacology, and biology care have contributed to progressively turn HIV infection from an unavoidably fatal condition into a chronic manageable disease, at least in the countries where HIV infected people have full access to the potent anti-retroviral (ARV) drug combinations that permit a marked and sustained control of viral replication. Although their pathogenesis is still under discussed, they are likely to originate from immune dysfunction associated with HIV infection and chronic inflammation. The last consideration regards the dis-homogenous pattern of HIV disease worldwide. Key-words- Human immunodeficiency virus (HIV), simian immunodeficiency viruses (SIV), Antiretroviral (ARV) therapy, Acquired immunodeficiency syndrome (AIDS), Cell mediated immunity (CMI), Anti-retroviral agents
potassium, chloride, bicarbonate, blood urea nitrogen (BUN), magnesium, creatinine, glucose, and sometimes calcium. Tests that focus on cholesterol levels can determine LDL and HDL cholesterol levels, as well as triglyceride levels.[6]
potassium, chloride, bicarbonate, blood urea nitrogen (BUN), magnesium, creatinine, glucose, and sometimes calcium. Tests that focus on cholesterol levels can determine LDL and HDL cholesterol levels, as well as triglyceride levels.[6]
3 postsRe Topic 2 DQ 2A recent global health issue to affec.docxdomenicacullison
3 posts
Re: Topic 2 DQ 2
A recent global health issue to affect many different world populations is Ebola. It has made news in the last few years due to multiple outbreaks. The Ebolavirus is part of the Filoviridae family and has six different species within its own categories. The most common for current outbreaks and infections is the Zaire strain (CDC n.d.). The incubation period spans from 2 days to 21 days in the susceptible host. It is transmitted via direct contact with infected bodily fluids and items contaminated with those secretions. Fatality rate for those infected is up to 50 percent, but early diagnosis and supportive treatment increases the odds of survival (CDC n.d.).
It is believed that the original host of the Ebolavirus is the fruit bat but can also be traced to other wild animals such as fruit flies, porcupines, and primates. The early signs/symptoms include fever, fatigue, muscle aches and pains, headache and sore throat. These symptoms often make it difficulty to distinguish the exact viral infection because many viruses mirror the same symptoms. These initial symptoms are followed by more intense vomiting, diarrhea, impaired kidney and liver functions, internal and external bleeding, decreased WBC and platelets, and increased liver enzymes. Hosts of the virus can only spread the infection when they have the active symptoms, therefore cannot spread infection during the incubation period. Exact diagnosis is done through several blood tests including the ELISA test, antigen-capture detection test, serum neutralization test, electron microscopy, and virus isolation by cell culture (CDC n.d.)
International monitoring of the Ebolavirus is done by the World Health Organization (WHO), under the United Nations. The WHO is considered to be the guardians of public health and security internationally and they are actively involved in setting up preventative and reactive programs/education. These programs are designed to decrease the possibility of an outbreak in any given population (GCU 2018). The response by WHO to the Ebolavirus outbreaks include supporting local and state health departments in disease detection, tracing the source of the outbreak, laboratory services, controlling the infection spread and instituting safe burial practices to prevent the spread of the virus (CDC n.d.). Preventative services by WHO include education on all levels to prevent outbreaks and attempts to break the chain of infection (CDC n.d.)
References
Centers for Disease Control and Prevention. (n.d.). Retrieved October 3, 2019, from
https://www.cdc.gov/
.
Grand Canyon University (Ed). (2018).
Community & public health: The future of health care.
Retrieved from https://lc.gcumedia.com/nrs427vn/community-and-public-health-the-future-of-health-care/v1.1/
.
Handout materials compiled by Dr. Ananda Balayogi Bhavanani for the SEMINAR-CUM-WORKSHOP ON YOGA AND COMPLEMENTARY THERAPIES FOR AIDS/HIV organised by the Advanced Centre for Yoga Therapy Education & Research (ACYTER), JIPMER for medical & paramedical professionals and yoga therapists at JIPMER, Pondicherry. The event was held on 30th January 2010 at the Multipurpose Hall, JIPMER Nursing College, JIPMER, Pondicherry-6.
Bio Whepon and COVID 19 - Is Corona Virus a Bio Weapon?Ravi Kumudesh
Is Corona Virus a Bio Weapon?
The Internet was brimming with conspiracies about the coronavirus, and, perhaps, one of the most prominent ones was that the virus could be a bioweapon.
According to an ET Prime report, a group of Chinese scientists in Canada were accused of spying and were stripped of their access to Canada’s National Microbiology Lab (NML) which is known to work on some of the most deadly pathogens.The alleged ‘policy breach’, highlighted the bioweapon program of other countries including China. Dr Francis Boyle, the creator of Bio Weapons Act, also claims that ‘the coronavirus is an offensive biological warfare weapon with DNA-genetic engineering’.Again, the claims about coronavirus being a biological weapon are unsubstantiated.
Novel Coronavirus thought to have transferred to Human from the seafood market in Wuhan, China become a one of the most dangerous viruses in the subfamily Orthocoronavirinae. According to the literature, the genome size of RNA of this viruses are greater than 20 kilobases.
Genetic engineers has committed to change the genes of some organisms to create new features of them, and this can be applied for the Coronavirus as well.
Burn injury is associated with high morbidity, long term disability and mortality. This phenomenon is seen all over the world, but is more pronounced in economically developing countries. Treatment of burn patients has evolved to a great extent today, but infection still continues to be the main cause of morbidity and mortality in the burn patients. Invasion of the burn wound by microbial pathogens leads to burn wound infections in burn patients. The risk of contracting a life threatening infection is high in burn patient due to the nature of the injury, an immunocompromised state, prolonged hospital stay and multiple interventions. Septic processes account for approximately 73 of all deaths within the initial five days of post burn. Burn patients usually have a prolonged stay in the burn unit. The microbiological profile of the organisms invading the burn wounds changes over time. A burn wound typically has large amounts of protein rich fluid exudate, which forms a healthy medium for bacterial growth. New burn admissions usually show the predominance of gram positive organisms in their wounds. Gram negative organisms become more prevalent as the duration of treatment increases. These organisms are potentially more invasive. Endogenous gram negative flora from the patient’s gut colonize the wounds within a few days of the burn. The gram positive flora, are the natural inhabitants of the skin. Infection in burn patient is not only one of the major reasons for mortality, but also for prolonging the hospital stay and delay skin cover procedures such as skin grafting. It is hence considered prudent for every burn institute to determine the changing anti microbial profile of the burn patients and their sensitivity pattern over time. The microbial flora affecting the burn wound is a dynamic entity and continues to evolve as the burn wound progresses. This change in the microbiological profile of the wound varies with each patient over the duration of his admission for the treatment of his burn injury and also in each burn unit over the time. Nosocomial organisms are commonly seen infecting the burn wounds and have multi drug resistance antimicrobial profiles.In addition, there was no comprehensive study done on the changing trends in the burn wound microbiology with emphasis on changing trends in the microbiological profile of burn wounds Arnab Majhi "Emerging Trends in Antimicrobial Resistance" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-3 , April 2022, URL: https://www.ijtsrd.com/papers/ijtsrd49780.pdf Paper URL: https://www.ijtsrd.com/other-scientific-research-area/other/49780/emerging-trends-in-antimicrobial-resistance/arnab-majhi
Microbial Toxins and Disease Development in Plantsijtsrd
Microbial toxins are those that produced by algae and may be accumulated in edible aquatic organisms such as shellfish phycotoxins are also included in this standard. Mycotoxins and phycotoxins are both subclasses of contaminants. Dr. Dilip Kumar Sharma "Microbial Toxins and Disease Development in Plants" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-6 , October 2022, URL: https://www.ijtsrd.com/papers/ijtsrd52247.pdf Paper URL: https://www.ijtsrd.com/biological-science/other/52247/microbial-toxins-and-disease-development-in-plants/dr-dilip-kumar-sharma
Travel-related infectious diseases on the rise
International travel has an important role in the transmission of emerging and re-emerging infectious diseases across geographical areas.
Since 1980, the world has been threatened by different waves of emerging disease epidemics.
In the twenty-first century, these diseases have become an increasing global concern because of their health and economic impacts in both developed and resource-constrained countries.
It is difficult to stop the occurrence of new pathogens in the future due to the interconnection among humans, animals, and the environment.
As many as 43%–79% of travelers to low- and middle-income countries become ill with a travel-related health problem.
Although most of these illnesses are mild, some travelers become sick enough to seek care from a health care provider.
Key question:
Could the plague ever re-emerge on a similar level in the twenty-first century?
Due to the potential seriousness of the disease this is a subject worthy of epidemiological consideration and research.
Austin Journal of Vector Borne Diseases: Open Access is an open access, peer reviewed, scholarly journal dedicated to publish articles in all areas of vector borne diseases including existing or new policy in the relevant areas, impact of all types of vector borne diseases and related medical research methodologies.
Vector-borne diseases are the infections transmitted by the bite of infected arthropod species, such as mosquitoes, ticks, triatomine bugs, sandflies, and blackflies. Arthropod vectors are cold-blooded (ectothermic) and thus especially sensitive to climatic factors. Or Vectors are organisms that transmit pathogens and parasites from one infected person (or animal) to another, causing serious diseases in human populations. These diseases are commonly found in tropical and sub-tropical regions and places where access to safe drinking-water and sanitation systems is problematic.
Austin Journal of vector borne diseases welcomes research manuscripts, review articles, case reports, editorials, letters to the editor, and innovations relating to all aspects of vector borne diseases.
Determination of Average HIV Replication in the Blood Plasma Using Truncated ...paperpublications3
Abstract: Many statistical and computational models have been developed to investigate the complexity of HIV dynamics in the immune response. Most of the models described the viral replication as a system of differential equation, where the solution of parameters is not easy to obtain. A model of HIV replication where infected cells undergo through a truncated logistic distribution is proposed. An infected cell is modelled as an individual entity with certain states and properties. Three simulation approaches are used for implementing the model, conditional distribution, truncated population mean approaches and sample mean. Simulation results give insights about the details of HIV replication dynamics inside the cell at the protein level. Therefore the model can be used for future studies of HIV intracellular replication. It will also promote better understanding of the HIV/AIDS transmission dynamics, the study will also add to the existing body of knowledge on mathematical application in the field of epidemiology.
‘Six Sigma Technique’ A Journey Through its Implementationijtsrd
The manufacturing industries all over the world are facing tough challenges for growth, development and sustainability in today’s competitive environment. They have to achieve apex position by adapting with the global competitive environment by delivering goods and services at low cost, prime quality and better price to increase wealth and consumer satisfaction. Cost Management ensures profit, growth and sustainability of the business with implementation of Continuous Improvement Technique like Six Sigma. This leads to optimize Business performance. The method drives for customer satisfaction, low variation, reduction in waste and cycle time resulting into a competitive advantage over other industries which did not implement it. The main objective of this paper ‘Six Sigma Technique A Journey Through Its Implementation’ is to conceptualize the effectiveness of Six Sigma Technique through the journey of its implementation. Aditi Sunilkumar Ghosalkar "‘Six Sigma Technique’: A Journey Through its Implementation" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64546.pdf Paper Url: https://www.ijtsrd.com/other-scientific-research-area/other/64546/‘six-sigma-technique’-a-journey-through-its-implementation/aditi-sunilkumar-ghosalkar
Edge Computing in Space Enhancing Data Processing and Communication for Space...ijtsrd
Edge computing, a paradigm that involves processing data closer to its source, has gained significant attention for its potential to revolutionize data processing and communication in space missions. With the increasing complexity and data volume generated by modern space missions, traditional centralized computing approaches face challenges related to latency, bandwidth, and security. Edge computing in space, involving on board processing and analysis of data, offers promising solutions to these challenges. This paper explores the concept of edge computing in space, its benefits, applications, and future prospects in enhancing space missions. Manish Verma "Edge Computing in Space: Enhancing Data Processing and Communication for Space Missions" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64541.pdf Paper Url: https://www.ijtsrd.com/computer-science/artificial-intelligence/64541/edge-computing-in-space-enhancing-data-processing-and-communication-for-space-missions/manish-verma
More Related Content
Similar to Virus and its Identification in Modern Era
potassium, chloride, bicarbonate, blood urea nitrogen (BUN), magnesium, creatinine, glucose, and sometimes calcium. Tests that focus on cholesterol levels can determine LDL and HDL cholesterol levels, as well as triglyceride levels.[6]
3 postsRe Topic 2 DQ 2A recent global health issue to affec.docxdomenicacullison
3 posts
Re: Topic 2 DQ 2
A recent global health issue to affect many different world populations is Ebola. It has made news in the last few years due to multiple outbreaks. The Ebolavirus is part of the Filoviridae family and has six different species within its own categories. The most common for current outbreaks and infections is the Zaire strain (CDC n.d.). The incubation period spans from 2 days to 21 days in the susceptible host. It is transmitted via direct contact with infected bodily fluids and items contaminated with those secretions. Fatality rate for those infected is up to 50 percent, but early diagnosis and supportive treatment increases the odds of survival (CDC n.d.).
It is believed that the original host of the Ebolavirus is the fruit bat but can also be traced to other wild animals such as fruit flies, porcupines, and primates. The early signs/symptoms include fever, fatigue, muscle aches and pains, headache and sore throat. These symptoms often make it difficulty to distinguish the exact viral infection because many viruses mirror the same symptoms. These initial symptoms are followed by more intense vomiting, diarrhea, impaired kidney and liver functions, internal and external bleeding, decreased WBC and platelets, and increased liver enzymes. Hosts of the virus can only spread the infection when they have the active symptoms, therefore cannot spread infection during the incubation period. Exact diagnosis is done through several blood tests including the ELISA test, antigen-capture detection test, serum neutralization test, electron microscopy, and virus isolation by cell culture (CDC n.d.)
International monitoring of the Ebolavirus is done by the World Health Organization (WHO), under the United Nations. The WHO is considered to be the guardians of public health and security internationally and they are actively involved in setting up preventative and reactive programs/education. These programs are designed to decrease the possibility of an outbreak in any given population (GCU 2018). The response by WHO to the Ebolavirus outbreaks include supporting local and state health departments in disease detection, tracing the source of the outbreak, laboratory services, controlling the infection spread and instituting safe burial practices to prevent the spread of the virus (CDC n.d.). Preventative services by WHO include education on all levels to prevent outbreaks and attempts to break the chain of infection (CDC n.d.)
References
Centers for Disease Control and Prevention. (n.d.). Retrieved October 3, 2019, from
https://www.cdc.gov/
.
Grand Canyon University (Ed). (2018).
Community & public health: The future of health care.
Retrieved from https://lc.gcumedia.com/nrs427vn/community-and-public-health-the-future-of-health-care/v1.1/
.
Handout materials compiled by Dr. Ananda Balayogi Bhavanani for the SEMINAR-CUM-WORKSHOP ON YOGA AND COMPLEMENTARY THERAPIES FOR AIDS/HIV organised by the Advanced Centre for Yoga Therapy Education & Research (ACYTER), JIPMER for medical & paramedical professionals and yoga therapists at JIPMER, Pondicherry. The event was held on 30th January 2010 at the Multipurpose Hall, JIPMER Nursing College, JIPMER, Pondicherry-6.
Bio Whepon and COVID 19 - Is Corona Virus a Bio Weapon?Ravi Kumudesh
Is Corona Virus a Bio Weapon?
The Internet was brimming with conspiracies about the coronavirus, and, perhaps, one of the most prominent ones was that the virus could be a bioweapon.
According to an ET Prime report, a group of Chinese scientists in Canada were accused of spying and were stripped of their access to Canada’s National Microbiology Lab (NML) which is known to work on some of the most deadly pathogens.The alleged ‘policy breach’, highlighted the bioweapon program of other countries including China. Dr Francis Boyle, the creator of Bio Weapons Act, also claims that ‘the coronavirus is an offensive biological warfare weapon with DNA-genetic engineering’.Again, the claims about coronavirus being a biological weapon are unsubstantiated.
Novel Coronavirus thought to have transferred to Human from the seafood market in Wuhan, China become a one of the most dangerous viruses in the subfamily Orthocoronavirinae. According to the literature, the genome size of RNA of this viruses are greater than 20 kilobases.
Genetic engineers has committed to change the genes of some organisms to create new features of them, and this can be applied for the Coronavirus as well.
Burn injury is associated with high morbidity, long term disability and mortality. This phenomenon is seen all over the world, but is more pronounced in economically developing countries. Treatment of burn patients has evolved to a great extent today, but infection still continues to be the main cause of morbidity and mortality in the burn patients. Invasion of the burn wound by microbial pathogens leads to burn wound infections in burn patients. The risk of contracting a life threatening infection is high in burn patient due to the nature of the injury, an immunocompromised state, prolonged hospital stay and multiple interventions. Septic processes account for approximately 73 of all deaths within the initial five days of post burn. Burn patients usually have a prolonged stay in the burn unit. The microbiological profile of the organisms invading the burn wounds changes over time. A burn wound typically has large amounts of protein rich fluid exudate, which forms a healthy medium for bacterial growth. New burn admissions usually show the predominance of gram positive organisms in their wounds. Gram negative organisms become more prevalent as the duration of treatment increases. These organisms are potentially more invasive. Endogenous gram negative flora from the patient’s gut colonize the wounds within a few days of the burn. The gram positive flora, are the natural inhabitants of the skin. Infection in burn patient is not only one of the major reasons for mortality, but also for prolonging the hospital stay and delay skin cover procedures such as skin grafting. It is hence considered prudent for every burn institute to determine the changing anti microbial profile of the burn patients and their sensitivity pattern over time. The microbial flora affecting the burn wound is a dynamic entity and continues to evolve as the burn wound progresses. This change in the microbiological profile of the wound varies with each patient over the duration of his admission for the treatment of his burn injury and also in each burn unit over the time. Nosocomial organisms are commonly seen infecting the burn wounds and have multi drug resistance antimicrobial profiles.In addition, there was no comprehensive study done on the changing trends in the burn wound microbiology with emphasis on changing trends in the microbiological profile of burn wounds Arnab Majhi "Emerging Trends in Antimicrobial Resistance" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-3 , April 2022, URL: https://www.ijtsrd.com/papers/ijtsrd49780.pdf Paper URL: https://www.ijtsrd.com/other-scientific-research-area/other/49780/emerging-trends-in-antimicrobial-resistance/arnab-majhi
Microbial Toxins and Disease Development in Plantsijtsrd
Microbial toxins are those that produced by algae and may be accumulated in edible aquatic organisms such as shellfish phycotoxins are also included in this standard. Mycotoxins and phycotoxins are both subclasses of contaminants. Dr. Dilip Kumar Sharma "Microbial Toxins and Disease Development in Plants" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-6 , October 2022, URL: https://www.ijtsrd.com/papers/ijtsrd52247.pdf Paper URL: https://www.ijtsrd.com/biological-science/other/52247/microbial-toxins-and-disease-development-in-plants/dr-dilip-kumar-sharma
Travel-related infectious diseases on the rise
International travel has an important role in the transmission of emerging and re-emerging infectious diseases across geographical areas.
Since 1980, the world has been threatened by different waves of emerging disease epidemics.
In the twenty-first century, these diseases have become an increasing global concern because of their health and economic impacts in both developed and resource-constrained countries.
It is difficult to stop the occurrence of new pathogens in the future due to the interconnection among humans, animals, and the environment.
As many as 43%–79% of travelers to low- and middle-income countries become ill with a travel-related health problem.
Although most of these illnesses are mild, some travelers become sick enough to seek care from a health care provider.
Key question:
Could the plague ever re-emerge on a similar level in the twenty-first century?
Due to the potential seriousness of the disease this is a subject worthy of epidemiological consideration and research.
Austin Journal of Vector Borne Diseases: Open Access is an open access, peer reviewed, scholarly journal dedicated to publish articles in all areas of vector borne diseases including existing or new policy in the relevant areas, impact of all types of vector borne diseases and related medical research methodologies.
Vector-borne diseases are the infections transmitted by the bite of infected arthropod species, such as mosquitoes, ticks, triatomine bugs, sandflies, and blackflies. Arthropod vectors are cold-blooded (ectothermic) and thus especially sensitive to climatic factors. Or Vectors are organisms that transmit pathogens and parasites from one infected person (or animal) to another, causing serious diseases in human populations. These diseases are commonly found in tropical and sub-tropical regions and places where access to safe drinking-water and sanitation systems is problematic.
Austin Journal of vector borne diseases welcomes research manuscripts, review articles, case reports, editorials, letters to the editor, and innovations relating to all aspects of vector borne diseases.
Determination of Average HIV Replication in the Blood Plasma Using Truncated ...paperpublications3
Abstract: Many statistical and computational models have been developed to investigate the complexity of HIV dynamics in the immune response. Most of the models described the viral replication as a system of differential equation, where the solution of parameters is not easy to obtain. A model of HIV replication where infected cells undergo through a truncated logistic distribution is proposed. An infected cell is modelled as an individual entity with certain states and properties. Three simulation approaches are used for implementing the model, conditional distribution, truncated population mean approaches and sample mean. Simulation results give insights about the details of HIV replication dynamics inside the cell at the protein level. Therefore the model can be used for future studies of HIV intracellular replication. It will also promote better understanding of the HIV/AIDS transmission dynamics, the study will also add to the existing body of knowledge on mathematical application in the field of epidemiology.
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‘Six Sigma Technique’ A Journey Through its Implementationijtsrd
The manufacturing industries all over the world are facing tough challenges for growth, development and sustainability in today’s competitive environment. They have to achieve apex position by adapting with the global competitive environment by delivering goods and services at low cost, prime quality and better price to increase wealth and consumer satisfaction. Cost Management ensures profit, growth and sustainability of the business with implementation of Continuous Improvement Technique like Six Sigma. This leads to optimize Business performance. The method drives for customer satisfaction, low variation, reduction in waste and cycle time resulting into a competitive advantage over other industries which did not implement it. The main objective of this paper ‘Six Sigma Technique A Journey Through Its Implementation’ is to conceptualize the effectiveness of Six Sigma Technique through the journey of its implementation. Aditi Sunilkumar Ghosalkar "‘Six Sigma Technique’: A Journey Through its Implementation" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64546.pdf Paper Url: https://www.ijtsrd.com/other-scientific-research-area/other/64546/‘six-sigma-technique’-a-journey-through-its-implementation/aditi-sunilkumar-ghosalkar
Edge Computing in Space Enhancing Data Processing and Communication for Space...ijtsrd
Edge computing, a paradigm that involves processing data closer to its source, has gained significant attention for its potential to revolutionize data processing and communication in space missions. With the increasing complexity and data volume generated by modern space missions, traditional centralized computing approaches face challenges related to latency, bandwidth, and security. Edge computing in space, involving on board processing and analysis of data, offers promising solutions to these challenges. This paper explores the concept of edge computing in space, its benefits, applications, and future prospects in enhancing space missions. Manish Verma "Edge Computing in Space: Enhancing Data Processing and Communication for Space Missions" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64541.pdf Paper Url: https://www.ijtsrd.com/computer-science/artificial-intelligence/64541/edge-computing-in-space-enhancing-data-processing-and-communication-for-space-missions/manish-verma
Dynamics of Communal Politics in 21st Century India Challenges and Prospectsijtsrd
Communal politics in India has evolved through centuries, weaving a complex tapestry shaped by historical legacies, colonial influences, and contemporary socio political transformations. This research comprehensively examines the dynamics of communal politics in 21st century India, emphasizing its historical roots, socio political dynamics, economic implications, challenges, and prospects for mitigation. The historical perspective unravels the intricate interplay of religious identities and power dynamics from ancient civilizations to the impact of colonial rule, providing insights into the evolution of communalism. The socio political dynamics section delves into the contemporary manifestations, exploring the roles of identity politics, socio economic disparities, and globalization. The economic implications section highlights how communal politics intersects with economic issues, perpetuating disparities and influencing resource allocation. Challenges posed by communal politics are scrutinized, revealing multifaceted issues ranging from social fragmentation to threats against democratic values. The prospects for mitigation present a multifaceted approach, incorporating policy interventions, community engagement, and educational initiatives. The paper conducts a comparative analysis with international examples, identifying common patterns such as identity politics and economic disparities. It also examines unique challenges, emphasizing Indias diverse religious landscape, historical legacy, and secular framework. Lessons for effective strategies are drawn from international experiences, offering insights into inclusive policies, interfaith dialogue, media regulation, and global cooperation. By scrutinizing historical epochs, contemporary dynamics, economic implications, and international comparisons, this research provides a comprehensive understanding of communal politics in India. The proposed strategies for mitigation underscore the importance of a holistic approach to foster social harmony, inclusivity, and democratic values. Rose Hossain "Dynamics of Communal Politics in 21st Century India: Challenges and Prospects" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64528.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/history/64528/dynamics-of-communal-politics-in-21st-century-india-challenges-and-prospects/rose-hossain
Assess Perspective and Knowledge of Healthcare Providers Towards Elehealth in...ijtsrd
Background and Objective Telehealth has become a well known tool for the delivery of health care in Saudi Arabia, and the perspective and knowledge of healthcare providers are influential in the implementation, adoption and advancement of the method. This systematic review was conducted to examine the current literature base regarding telehealth and the related healthcare professional perspective and knowledge in the Kingdom of Saudi Arabia. Materials and Methods This systematic review was conducted by searching 7 databases including, MEDLINE, CINHAL, Web of Science, Scopus, PubMed, PsycINFO, and ProQuest Central. Studies on healthcare practitioners telehealth knowledge and perspectives published in English in Saudi Arabia from 2000 to 2023 were included. Boland directed this comprehensive review. The researchers examined each connected study using the AXIS tool, which evaluates cross sectional systematic reviews. Narrative synthesis was used to summarise and convey the data. Results Out of 1840 search results, 10 studies were included. Positive outlook and limited knowledge among providers were seen across trials. Healthcare professionals like telehealth for its ability to improve quality, access, and delivery, save time and money, and be successful. Age, gender, occupation, and work experience also affect health workers knowledge. In Saudi Arabia, healthcare professionals face inadequate expert assistance, patient privacy, internet connection concerns, lack of training courses, lack of telehealth understanding, and high costs while performing telemedicine. Conclusions Healthcare practitioners telehealth perceptions and knowledge were examined in this systematic study. Its collection of concerned experts different personal attitudes and expertise would help enhance telehealths implementation in Saudi Arabia, develop its healthcare delivery alternative, and eliminate frequent problems. Badriah Mousa I Mulayhi | Dr. Jomin George | Judy Jenkins "Assess Perspective and Knowledge of Healthcare Providers Towards Elehealth in Saudi Arabia: A Systematic Review" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64535.pdf Paper Url: https://www.ijtsrd.com/medicine/other/64535/assess-perspective-and-knowledge-of-healthcare-providers-towards-elehealth-in-saudi-arabia-a-systematic-review/badriah-mousa-i-mulayhi
The Impact of Digital Media on the Decentralization of Power and the Erosion ...ijtsrd
The impact of digital media on the distribution of power and the weakening of traditional gatekeepers has gained considerable attention in recent years. The adoption of digital technologies and the internet has resulted in declining influence and power for traditional gatekeepers such as publishing houses and news organizations. Simultaneously, digital media has facilitated the emergence of new voices and players in the media industry. Digital medias impact on power decentralization and gatekeeper erosion is visible in several ways. One significant aspect is the democratization of information, which enables anyone with an internet connection to publish and share content globally, leading to citizen journalism and bypassing traditional gatekeepers. Another aspect is the disruption of conventional media industry business models, as traditional organizations struggle to adjust to the decrease in advertising revenue and the rise of digital platforms. Alternative business models, such as subscription models and crowdfunding, have become more prevalent, leading to the emergence of new players. Overall, the impact of digital media on the distribution of power and the weakening of traditional gatekeepers has brought about significant changes in the media landscape and the way information is shared. Further research is required to fully comprehend the implications of these changes and their impact on society. Dr. Kusum Lata "The Impact of Digital Media on the Decentralization of Power and the Erosion of Traditional Gatekeepers" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64544.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/political-science/64544/the-impact-of-digital-media-on-the-decentralization-of-power-and-the-erosion-of-traditional-gatekeepers/dr-kusum-lata
Online Voices, Offline Impact Ambedkars Ideals and Socio Political Inclusion ...ijtsrd
This research investigates the nexus between online discussions on Dr. B.R. Ambedkars ideals and their impact on social inclusion among college students in Gurugram, Haryana. Surveying 240 students from 12 government colleges, findings indicate that 65 actively engage in online discussions, with 80 demonstrating moderate to high awareness of Ambedkars ideals. Statistically significant correlations reveal that higher online engagement correlates with increased awareness p 0.05 and perceived social inclusion. Variations across colleges and a notable effect of college type on perceived social inclusion highlight the influence of contextual factors. Furthermore, the intersectional analysis underscores nuanced differences based on gender, caste, and socio economic status. Dr. Kusum Lata "Online Voices, Offline Impact: Ambedkar's Ideals and Socio-Political Inclusion - A Study of Gurugram District" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64543.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/political-science/64543/online-voices-offline-impact-ambedkars-ideals-and-sociopolitical-inclusion--a-study-of-gurugram-district/dr-kusum-lata
Problems and Challenges of Agro Entreprenurship A Studyijtsrd
Noting calls for contextualizing Agro entrepreneurs problems and challenges of the agro entrepreneurs and for greater attention to the Role of entrepreneurs in agro entrepreneurship research, we conduct a systematic literature review of extent research in agriculture entrepreneurship to overcome the study objectives of complications of agro entrepreneurs through various factors, Development of agriculture products is a key factor for the overall economic growth of agro entrepreneurs Agro Entrepreneurs produces firsthand large scale employment, utilizes the labor and natural resources, This research outlines the problems of Weather and Soil Erosions, Market price fluctuation, stimulates labor cost problems, reduces concentration of Price volatility, Dependency on Intermediaries, induces Limited Bargaining Power, and Storage and Transportation Costs. This paper mainly devoted to highlight Problems and challenges faced for the sustainable of Agro Entrepreneurs in India. Vinay Prasad B "Problems and Challenges of Agro Entreprenurship - A Study" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64540.pdf Paper Url: https://www.ijtsrd.com/other-scientific-research-area/other/64540/problems-and-challenges-of-agro-entreprenurship--a-study/vinay-prasad-b
Comparative Analysis of Total Corporate Disclosure of Selected IT Companies o...ijtsrd
Disclosure is a process through which a business enterprise communicates with external parties. A corporate disclosure is communication of financial and non financial information of the activities of a business enterprise to the interested entities. Corporate disclosure is done through publishing annual reports. So corporate disclosure through annual reports plays a vital role in the life of all the companies and provides valuable information to investors. The basic objectives of corporate disclosure is to give a true and fair view of companies to the parties related either directly or indirectly like owner, government, creditors, shareholders etc. in the companies act, provisions have been made about mandatory and voluntary disclosure. The IT sector in India is rapidly growing, the trend to invest in the IT sector is rising and employment opportunities in IT sectors are also increasing. Therefore the IT sector is expected to have fair, full and adequate disclosure of all information. Unfair and incomplete disclosure may adversely affect the entire economy. A research study on disclosure practices of IT companies could play an important role in this regard. Hence, the present research study has been done to study and review comparative analysis of total corporate disclosure of selected IT companies of India and to put forward overall findings and suggestions with a view to increase disclosure score of these companies. The researcher hopes that the present research study will be helpful to all selected Companies for improving level of corporate disclosure through annual reports as well as the government, creditors, investors, all business organizations and upcoming researcher for comparative analyses of level of corporate disclosure with special reference to selected IT companies. Dr. Vaibhavi D. Thaker "Comparative Analysis of Total Corporate Disclosure of Selected IT Companies of India" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64539.pdf Paper Url: https://www.ijtsrd.com/other-scientific-research-area/other/64539/comparative-analysis-of-total-corporate-disclosure-of-selected-it-companies-of-india/dr-vaibhavi-d-thaker
The Impact of Educational Background and Professional Training on Human Right...ijtsrd
This study investigated the impact of educational background and professional training on human rights awareness among secondary school teachers in the Marathwada region of Maharashtra, India. The key findings reveal that higher levels of education, particularly a master’s degree, and fields of study related to education, humanities, or social sciences are associated with greater human rights awareness among teachers. Additionally, both pre service teacher training and in service professional development programs focused on human rights education significantly enhance teacher’s knowledge, skills, and competencies in promoting human rights principles in their classrooms. Baig Ameer Bee Mirza Abdul Aziz | Dr. Syed Azaz Ali Amjad Ali "The Impact of Educational Background and Professional Training on Human Rights Awareness among Secondary School Teachers" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64529.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/education/64529/the-impact-of-educational-background-and-professional-training-on-human-rights-awareness-among-secondary-school-teachers/baig-ameer-bee-mirza-abdul-aziz
A Study on the Effective Teaching Learning Process in English Curriculum at t...ijtsrd
“One Language sets you in a corridor for life. Two languages open every door along the way” Frank Smith English as a foreign language or as a second language has been ruling in India since the period of Lord Macaulay. But the question is how much we teach or learn English properly in our culture. Is there any scope to use English as a language rather than a subject How much we learn or teach English without any interference of mother language specially in the classroom teaching learning scenario in West Bengal By considering all these issues the researcher has attempted in this article to focus on the effective teaching learning process comparing to other traditional strategies in the field of English curriculum at the secondary level to investigate whether they fulfill the present teaching learning requirements or not by examining the validity of the present curriculum of English. The purpose of this study is to focus on the effectiveness of the systematic, scientific, sequential and logical transaction of the course between the teachers and the learners in the perspective of the 5Es programme that is engage, explore, explain, extend and evaluate. Sanchali Mondal | Santinath Sarkar "A Study on the Effective Teaching Learning Process in English Curriculum at the Secondary Level of West Bengal" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd62412.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/education/62412/a-study-on-the-effective-teaching-learning-process-in-english-curriculum-at-the-secondary-level-of-west-bengal/sanchali-mondal
The Role of Mentoring and Its Influence on the Effectiveness of the Teaching ...ijtsrd
This paper reports on a study which was conducted to investigate the role of mentoring and its influence on the effectiveness of the teaching of Physics in secondary schools in the South West Region of Cameroon. The study adopted the convergent parallel mixed methods design, focusing on respondents in secondary schools in the South West Region of Cameroon. Both quantitative and qualitative data were collected, analysed separately, and the results were compared to see if the findings confirm or disconfirm each other. The quantitative analysis found that majority of the respondents 72 of Physics teachers affirmed that they had more experienced colleagues as mentors to help build their confidence, improve their teaching, and help them improve their effectiveness and efficiency in guiding learners’ achievements. Only 28 of the respondents disagreed with these statements. With majority respondents 72 agreeing with the statements, it implies that in most secondary schools, experienced Physics teachers act as mentors to build teachers’ confidence in teaching and improving students’ learning. The interview qualitative data analysis summarized how secondary school Principals use meetings with mentors and mentees to promote mentorship in the school milieu. This has helped strengthen teachers’ classroom practices in secondary schools in the South West Region of Cameroon. With the results confirming each other, the study recommends that mentoring should focus on helping teachers employ social interactions and instructional practices feedback and clarity in teaching that have direct measurable impact on students’ learning achievements. Andrew Ngeim Sumba | Frederick Ebot Ashu | Peter Agborbechem Tambi "The Role of Mentoring and Its Influence on the Effectiveness of the Teaching of Physics in Secondary Schools in the South West Region of Cameroon" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64524.pdf Paper Url: https://www.ijtsrd.com/management/management-development/64524/the-role-of-mentoring-and-its-influence-on-the-effectiveness-of-the-teaching-of-physics-in-secondary-schools-in-the-south-west-region-of-cameroon/andrew-ngeim-sumba
Design Simulation and Hardware Construction of an Arduino Microcontroller Bas...ijtsrd
This study primarily focuses on the design of a high side buck converter using an Arduino microcontroller. The converter is specifically intended for use in DC DC applications, particularly in standalone solar PV systems where the PV output voltage exceeds the load or battery voltage. To evaluate the performance of the converter, simulation experiments are conducted using Proteus Software. These simulations provide insights into the input and output voltages, currents, powers, and efficiency under different state of charge SoC conditions of a 12V,70Ah rechargeable lead acid battery. Additionally, the hardware design of the converter is implemented, and practical data is collected through operation, monitoring, and recording. By comparing the simulation results with the practical results, the efficiency and performance of the designed converter are assessed. The findings indicate that while the buck converter is suitable for practical use in standalone PV systems, its efficiency is compromised due to a lower output current. Chan Myae Aung | Dr. Ei Mon "Design Simulation and Hardware Construction of an Arduino-Microcontroller Based DC-DC High-Side Buck Converter for Standalone PV System" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64518.pdf Paper Url: https://www.ijtsrd.com/engineering/mechanical-engineering/64518/design-simulation-and-hardware-construction-of-an-arduinomicrocontroller-based-dcdc-highside-buck-converter-for-standalone-pv-system/chan-myae-aung
Sustainable Energy by Paul A. Adekunte | Matthew N. O. Sadiku | Janet O. Sadikuijtsrd
Energy becomes sustainable if it meets the needs of the present without compromising the ability of future generations to meet their own needs. Some of the definitions of sustainable energy include the considerations of environmental aspects such as greenhouse gas emissions, social, and economic aspects such as energy poverty. Generally far more sustainable than fossil fuel are renewable energy sources such as wind, hydroelectric power, solar, and geothermal energy sources. Worthy of note is that some renewable energy projects, like the clearing of forests to produce biofuels, can cause severe environmental damage. The sustainability of nuclear power which is a low carbon source is highly debated because of concerns about radioactive waste, nuclear proliferation, and accidents. The switching from coal to natural gas has environmental benefits, including a lower climate impact, but could lead to delay in switching to more sustainable options. “Carbon capture and storage” can be built into power plants to remove the carbon dioxide CO2 emissions, but this technology is expensive and has rarely been implemented. Leading non renewable energy sources around the world is fossil fuels, coal, petroleum, and natural gas. Nuclear energy is usually considered another non renewable energy source, although nuclear energy itself is a renewable energy source, but the material used in nuclear power plants is not. The paper addresses the issue of sustainable energy, its attendant benefits to the future generation, and humanity in general. Paul A. Adekunte | Matthew N. O. Sadiku | Janet O. Sadiku "Sustainable Energy" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64534.pdf Paper Url: https://www.ijtsrd.com/engineering/electrical-engineering/64534/sustainable-energy/paul-a-adekunte
Concepts for Sudan Survey Act Implementations Executive Regulations and Stand...ijtsrd
This paper aims to outline the executive regulations, survey standards, and specifications required for the implementation of the Sudan Survey Act, and for regulating and organizing all surveying work activities in Sudan. The act has been discussed for more than 5 years. The Land Survey Act was initiated by the Sudan Survey Authority and all official legislations were headed by the Sudan Ministry of Justice till it was issued in 2022. The paper presents conceptual guidelines to be used for the Survey Act implementation and to regulate the survey work practice, standardizing the field surveys, processing, quality control, procedures, and the processes related to survey work carried out by the stakeholders and relevant authorities in Sudan. The conceptual guidelines are meant to improve the quality and harmonization of geospatial data and to aid decision making processes as well as geospatial information systems. The established comprehensive executive regulations will govern and regulate the implementation of the Sudan Survey Geomatics Act in all surveying and mapping practices undertaken by the Sudan Survey Authority SSA and state local survey departments for public or private sector organizations. The targeted standards and specifications include the reference frame, projection, coordinate systems, and the guidelines and specifications that must be followed in the field of survey work, processes, and mapping products. In the last few decades, there has been a growing awareness of the importance of geomatics activities and measurements on the Earths surface in space and time, together with observing and mapping the changes. In such cases, data must be captured promptly, standardized, and obtained with more accuracy and specified in much detail. The paper will also highlight the current situation in Sudan, the degree to which survey standards are used, the problems encountered, and the errors that arise from not using the standards and survey specifications. Kamal A. A. Sami "Concepts for Sudan Survey Act Implementations - Executive Regulations and Standards" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63484.pdf Paper Url: https://www.ijtsrd.com/engineering/civil-engineering/63484/concepts-for-sudan-survey-act-implementations--executive-regulations-and-standards/kamal-a-a-sami
Towards the Implementation of the Sudan Interpolated Geoid Model Khartoum Sta...ijtsrd
The discussions between ellipsoid and geoid have invoked many researchers during the recent decades, especially during the GNSS technology era, which had witnessed a great deal of development but still geoid undulation requires more investigations. To figure out a solution for Sudans local geoid, this research has tried to intake the possibility of determining the geoid model by following two approaches, gravimetric and geometrical geoid model determination, by making use of GNSS leveling benchmarks at Khartoum state. The Benchmarks are well distributed in the study area, in which, the horizontal coordinates and the height above the ellipsoid have been observed by GNSS while orthometric heights were carried out using precise leveling. The Global Geopotential Model GGM represented in EGM2008 has been exploited to figure out the geoid undulation at the benchmarks in the study area. This is followed by a fitting process, that has been done to suit the geoid undulation data which has been computed using GNSS leveling data and geoid undulation inspired by the EGM2008. Two geoid surfaces were created after the fitting process to ensure that they are identical and both of them could be counted for getting the same geoid undulation with an acceptable accuracy. In this respect, statistical operation played an important role in ensuring the consistency and integrity of the model by applying cross validation techniques splitting the data into training and testing datasets for building the geoid model and testing its eligibility. The geometrical solution for geoid undulation computation has been utilized by applying straightforward equations that facilitate the calculation of the geoid undulation directly through applying statistical techniques for the GNSS leveling data of the study area to get the common equation parameters values that could be utilized to calculate geoid undulation of any position in the study area within the claimed accuracy. Both systems were checked and proved eligible to be used within the study area with acceptable accuracy which may contribute to solving the geoid undulation problem in the Khartoum area, and be further generalized to determine the geoid model over the entire country, and this could be considered in the future, for regional and continental geoid model. Ahmed M. A. Mohammed. | Kamal A. A. Sami "Towards the Implementation of the Sudan Interpolated Geoid Model (Khartoum State Case Study)" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63483.pdf Paper Url: https://www.ijtsrd.com/engineering/civil-engineering/63483/towards-the-implementation-of-the-sudan-interpolated-geoid-model-khartoum-state-case-study/ahmed-m-a-mohammed
Activating Geospatial Information for Sudans Sustainable Investment Mapijtsrd
Sudan is witnessing an acceleration in the processes of development and transformation in the performance of government institutions to raise the productivity and investment efficiency of the government sector. The development plans and investment opportunities have focused on achieving national goals in various sectors. This paper aims to illuminate the path to the future and provide geospatial data and information to develop the investment climate and environment for all sized businesses, and to bridge the development gap between the Sudan states. The Sudan Survey Authority SSA is the main advisor to the Sudan Government in conducting surveying, mappings, designing, and developing systems related to geospatial data and information. In recent years, SSA made a strategic partnership with the Ministry of Investment to activate Geospatial Information for Sudans Sustainable Investment and in particular, for the preparation and implementation of the Sudan investment map, based on the directives and objectives of the Ministry of Investment MI in Sudan. This paper comes within the framework of activating the efforts of the Ministry of Investment to develop technical investment services by applying techniques adopted by the Ministry and its strategic partners for advancing investment processes in the country. Kamal A. A. Sami "Activating Geospatial Information for Sudan's Sustainable Investment Map" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63482.pdf Paper Url: https://www.ijtsrd.com/engineering/information-technology/63482/activating-geospatial-information-for-sudans-sustainable-investment-map/kamal-a-a-sami
Educational Unity Embracing Diversity for a Stronger Societyijtsrd
In a rapidly changing global landscape, the importance of education as a unifying force cannot be overstated. This paper explores the crucial role of educational unity in fostering a stronger and more inclusive society through the embrace of diversity. By examining the benefits of diverse learning environments, the paper aims to highlight the positive impact on societal strength. The discussion encompasses various dimensions, from curriculum design to classroom dynamics, and emphasizes the need for educational institutions to become catalysts for unity in diversity. It highlights the need for a paradigm shift in educational policies, curricula, and pedagogical approaches to ensure that they are reflective of the diverse fabric of society. This paper also addresses the challenges associated with implementing inclusive educational practices and offers practical strategies for overcoming barriers. It advocates for collaborative efforts between educational institutions, policymakers, and communities to create a supportive ecosystem that promotes diversity and unity. Mr. Amit Adhikari | Madhumita Teli | Gopal Adhikari "Educational Unity: Embracing Diversity for a Stronger Society" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64525.pdf Paper Url: https://www.ijtsrd.com/humanities-and-the-arts/education/64525/educational-unity-embracing-diversity-for-a-stronger-society/mr-amit-adhikari
Integration of Indian Indigenous Knowledge System in Management Prospects and...ijtsrd
The diversity of indigenous knowledge systems in India is vast and can vary significantly between different communities and regions. Preserving and respecting these knowledge systems is crucial for maintaining cultural heritage, promoting sustainable practices, and fostering cross cultural understanding. In this paper, an overview of the prospects and challenges associated with incorporating Indian indigenous knowledge into management is explored. It is found that IIKS helps in management in many areas like sustainable development, tourism, food security, natural resource management, cultural preservation and innovation, etc. However, IIKS integration with management faces some challenges in the form of a lack of documentation, cultural sensitivity, language barriers legal framework, etc. Savita Lathwal "Integration of Indian Indigenous Knowledge System in Management: Prospects and Challenges" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63500.pdf Paper Url: https://www.ijtsrd.com/management/accounting-and-finance/63500/integration-of-indian-indigenous-knowledge-system-in-management-prospects-and-challenges/savita-lathwal
DeepMask Transforming Face Mask Identification for Better Pandemic Control in...ijtsrd
The COVID 19 pandemic has highlighted the crucial need of preventive measures, with widespread use of face masks being a key method for slowing the viruss spread. This research investigates face mask identification using deep learning as a technological solution to be reducing the risk of coronavirus transmission. The proposed method uses state of the art convolutional neural networks CNNs and transfer learning to automatically recognize persons who are not wearing masks in a variety of circumstances. We discuss how this strategy improves public health and safety by providing an efficient manner of enforcing mask wearing standards. The report also discusses the obstacles, ethical concerns, and prospective applications of face mask detection systems in the ongoing fight against the pandemic. Dilip Kumar Sharma | Aaditya Yadav "DeepMask: Transforming Face Mask Identification for Better Pandemic Control in the COVID-19 Era" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64522.pdf Paper Url: https://www.ijtsrd.com/engineering/electronics-and-communication-engineering/64522/deepmask-transforming-face-mask-identification-for-better-pandemic-control-in-the-covid19-era/dilip-kumar-sharma
Streamlining Data Collection eCRF Design and Machine Learningijtsrd
Efficient and accurate data collection is paramount in clinical trials, and the design of Electronic Case Report Forms eCRFs plays a pivotal role in streamlining this process. This paper explores the integration of machine learning techniques in the design and implementation of eCRFs to enhance data collection efficiency. We delve into the synergies between eCRF design principles and machine learning algorithms, aiming to optimize data quality, reduce errors, and expedite the overall data collection process. The application of machine learning in eCRF design brings forth innovative approaches to data validation, anomaly detection, and real time adaptability. This paper discusses the benefits, challenges, and future prospects of leveraging machine learning in eCRF design for streamlined and advanced data collection in clinical trials. Dhanalakshmi D | Vijaya Lakshmi Kannareddy "Streamlining Data Collection: eCRF Design and Machine Learning" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd63515.pdf Paper Url: https://www.ijtsrd.com/biological-science/biotechnology/63515/streamlining-data-collection-ecrf-design-and-machine-learning/dhanalakshmi-d
We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Ethnobotany and Ethnopharmacology:
Ethnobotany in herbal drug evaluation,
Impact of Ethnobotany in traditional medicine,
New development in herbals,
Bio-prospecting tools for drug discovery,
Role of Ethnopharmacology in drug evaluation,
Reverse Pharmacology.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
The Indian economy is classified into different sectors to simplify the analysis and understanding of economic activities. For Class 10, it's essential to grasp the sectors of the Indian economy, understand their characteristics, and recognize their importance. This guide will provide detailed notes on the Sectors of the Indian Economy Class 10, using specific long-tail keywords to enhance comprehension.
For more information, visit-www.vavaclasses.com
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left untreated, it can become permanent, because it
can escape from the control of the immune system.
In the last 30 years, there have been significant
changes in the epidemiology of viruses associated
with human infections. While many viruses (such as
the West Nile virus) have spread to regions where
they had never been detected before, others have
caused global concern after a long period of silence,
such as the Zika virus. Apart from this, new viruses
have emerged and caused regional and global
epidemics, such as theMiddle East respiratory
syndrome-related coronavirus (MERS-CoV) and
severe acute respiratory syndrome-related coronavirus
2 (SARS-CoV-2). Moreover, due to developments in
molecular biology and genetics, it is also important to
monitor the natural viruses and modified viruses that
can be manipulated more easily and which have the
potential to be used as biological warfare agents.
Viruses are mainly transmitted to humans through the
respiratory tract, food and drink, skin, and blood.
Some viruses are transmitted to humans by insects,
such as mosquitoes and ticks, and mammals, such as
cats, dogs, mice, bats, and birds. Since viruses are
host-dependent micro-organisms, their distribution in
geographic regions is directly related to their host
distribution. Humans are the only hosts of some
viruses in nature; such viruses, which do not have an
animal reservoir, continue their existence by
spreading among people. Cultural habits, nutritional
and sanitation conditions, the frequency of risky
behaviors, drug addiction, the proportion of the
immune deficient population in a society, access to
health services, vaccination programs, and other
health policies are some of the social characteristics
that define the boundaries of the epidemiology of
these viruses. On the other hand, in the distribution of
animal viruses associated with human infections
(zoonotic viruses), the possibility of contact between
humans and animals (for example, the intersection of
the habitats of humans and reservoir animals) plays
an important role in viral epidemiology. The effects
of climate change on the circulation of migratory
birds and arthropods such as mosquitoes, human
movements that have accelerated with the increase in
transportation facilities, and forced migration are
other factors that determine the distribution
boundaries of viral diversity in human populations.
Importance of virus detection:
Typical (pathognomonic) symptoms with diagnostic
value can be seen in some viral infections. However,
in most viral infections, the clinical findings are
similar to those for multiple viruses, and sometimes
infections can take place without any symptoms
(asymptomatic). Therefore, precise diagnoses of viral
infections are carried out using laboratory tests
(figure 1.1). Viral infections can be diagnosed
directly by methods such as the visualization of
viruses, the detection of viral antigens, the isolation of
a virus by replicating it in a cell culture medium, and
by the observation of viral nucleic acids. Viral
infections can also be identified indirectly by
different methods, such as the detection of virus-
specific antibodies, the examination of changes (such
as inclusion bodies) in infected cells using light
microscopy, and the indirect examination of growths
in cell cultures. Laboratory tests are also used for
different clinical purposes, such as monitoring the
patient in some infections, investigating the presence
of antiviral resistance, and distinguishing between
primary and reactivated infections. The detection of
viruses is also critically important in epidemic
outbreak surveillance and other epidemiological and
environmental analyses, phylogenetic studies, the
screening of blood and blood products, veterinary
studies, and tests for biosecurity breaches (due to the
risk that a virus may be used as a biological weapon).
Figure: virus Detection
Nowadays, new molecular techniques that allow the
detection of unknown microorganisms, specific cell
lines, and chimeric cultures, animal models that
increase the probability of isolation of viruses, and
metagenomic-metaviromic studies have increased the
number of known viruses and made it possible to
monitor genomic variations and epidemiological
changes in these viruses. The fast detection of
pathogens, using methods that offer specific,
sensitive, fast, and reproducible results, plays an
important role in preventing the spread of viral
infections and decreasing the pathologies (mortality
and morbidity) associated with infection. Rapid
identification of the presence of a virus in
contaminated food or water, surfaces, or patient
samples is a prerequisite for effectively preventing
viral outbreaks, epidemics, and bioterrorism. As we
have experienced in the SARS-CoV-2 pandemic, it is
far from realistic for developed countries to isolate
themselves from the rest of the world due to intense
and rapid human movement. For these reasons, the
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development of easy-to-use, low-cost detection
methods that require fewer complex devices and
equipment in epidemic management and isolation-
based public health policies is critical in the
management of global epidemics.
Coronavirus:
Coronavirus The name coronavirus is derived from
the Latin word ‘corona,’ meaning halo, which
expresses the similarity of the characteristic
appearance of the surface protrusions of the virus to
the halo (solar corona) around the Sun. There are 46
virus species in five genera in the Coronaviridae
family. Six of these species were known to be
associated with human infection. In the last days of
2019, a new coronavirus identified as a pneumonia
agent, which first appeared in Wuhan, China, spread
rapidly among people, and the number of coronavirus
species associated with human infection was updated
to seven. Among these viruses, HCoV-229E (mid-
1960), HCoV-OC43 (mid-1960), NL63 (in 2004), and
HCoV-HKU1 (in 2005) are known to be seasonal
coronaviruses that are common worldwide and which
cause respiratory infections that are generally
associated with mild symptoms in humans.
Figure: Corona- virus
The major transmission route of coronaviruses in
humans, which is similar to those of other respiratory
viruses, is through the inhalation of droplets
containing infective viral particles produced when an
infected person speaks, coughs, or sneezes. Although
it is not a predominant transmission mode, touching
the mouth, nose, or eyes (autoinoculation) after
contact with virus-contaminated surfaces or fomites is
also considered to be one of the possible transmission
routes. The most effective way to prevent coronavirus
infections, which exhibit similar transmission
characteristics to those of other respiratory infections,
includes standard measures taken to prevent droplet
and aerosol transmission. Inactivated full-virus
vaccines, messenger RNA (ribonucleic acid)
vaccines, and vector-based vaccines developed within
about a year of the onset of the SARS-CoV-2
epidemic have been administered to millions of
people worldwide. Even if these vaccines do not
prevent the transmission of infection, they are
expected to prevent serious illnesses requiring
hospitalization and SARS-CoV-2 related deaths and
slow the spread of the epidemic. The protection
period and protective effectiveness of vaccines in
different populations are expected to be revealed in
upcoming studies. Laboratory diagnosis of
coronavirus infections is based on tests that aim to
detect viral RNA using a PCR (polymerase chain
reaction) and viral antigens or specific antibodies
against the virus. Virus isolation is time-consuming; it
is not used in routine diagnosis and also requires a
biosafety level 3 (BSL-3) laboratory using BSL-3
practices. During the COVID-19 pandemic, it has
been of great importance for the rapid and correct
diagnosis of cases, for the detection and isolation of
people with asymptomatic infections who can spread
the infection, and to keep the pandemic under control.
For this purpose, many biosensor-based methods have
also been developed.
Human immunodeficiency virus:
There are ten different viruses in the Lentivirus genus
of the Retroviridae family, and two of these viruses,
human immunodeficiency virus 1 (HIV-1) and HIV-
2, are associated with human infection.The disease
known as acquired immunodeficiency syndrome
(AIDS) was first reported in 1981 in the United States
of America (USA) in a group of homosexual men
with Pneumocystis jirovecii pneumonia and Kaposi’s
sarcoma. In 1982, some researchers from the CDC
(Centers for Disease Control and Prevention)
described similar cases in injected-drug users, sex
workers, and people using blood and blood products.
As a result of subsequent studies, the HIV-1 and HIV-
2 viruses were found to be infectious agents for AIDS
in 1983 and 1986, respectively. HIV-1 accounts for
the vast majority of human lentivirus-originated
disease worldwide. HIV-2, whose genetic
composition and disease symptoms are verysimilar to
HIV-1, is endemic in West Africa and is seen in the
USA, albeit at low rates. Within days or weeks
following exposure to HIV, a disease picture that is
defined as primary HIV infection (acute viral
syndrome) and which usually presents acute flu-like
symptoms occurs in most infected individuals. AIDS
patients typically show signs of a selective decrease
in the CD4+ helper-T lymphocytes in their peripheral
blood samples and immune system failure, which is
due to this decrease. After acute infection, due to the
establishment of a balance between viral replication
and host immune response, a latency period begins,
during which clinical symptoms are not seen for
many years in most infected individuals. However,
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the phrase ‘latency period’ can be misleading, given
the very high rate of virus replication and the high
daily production–destruction rate of CD4+ T-cells.
Because this process causes a gradual decrease in
CD4+ T-cells, albeit slowly, when the CD4+ T-cell
ratio falls below 200 µL−1, many AIDS defining
diseases, including various opportunistic infections
and some cancers, are seen, and the process results in
death in untreated cases.
Although an effective treatment exists today, these
high mortality rates seem to be related to the inability
to control the infection in regions where the majority
of infected individuals have limited access to
treatment. All these data highlight that HIV is one of
the most important viral infections that has affected
humanity in the last 40 years. HIV infection is
transmitted mainly by unprotected sexual intercourse
with an infected partner, the injection or transfusion
of contaminated blood or blood products, infertility
treatment practices, skin grafting, organ
transplantation, the sharing of non-sterile injection
equipment previously used by an infected person, and
mother-to-baby transmission (during pregnancy,
birth, and breastfeeding).
A preventive vaccine has not yet been developed for
HIV infection. To reduce the effects of infection and
to control or eliminate HIV-1 reservoirs, there is
increasing interest in the use of agents that activate
the latent virus, therapeutic vaccines, widely
neutralizing monoclonal antibodies, gene therapy, and
a variety of other pharmacological and
immunological approaches.
Many different tests can be used to diagnose acute
HIV-1 infection. Laboratory diagnosis of HIV
infection is based on the detection of virus and virus
components including viral deoxyribonucleic acid
(DNA), RNA, and antigens, as well as antibodies
against the viral antigens in the blood. The diagnosis
of acute infection is based on the detection of HIV-1
replication by molecular methods in the absence of
HIV-1 antibodies (as they are not yet present in the
early stages of infection).
Hepatitis:
During many viral infections, liver tissue can be
directly or indirectly affected, and hepatitis may
develop. However, the definition of hepatitis viruses
is used to refer to viruses that show tropism directly
to the liver: the hepatitis A virus (Hepatovirus A), the
hepatitis B virus, the hepatitis C virus (Hepacivirus
C), the hepatitis D virus (of the hepatitis genus
Deltavirus), and the hepatitis E virus (Orthohepevirus
A). Each of these viruses is classified as belonging to
a different family, and they are RNA viruses except
for the hepatitis B virus, whose genome structure is
DNA. Among these viruses, hepatitis B and C viruses
can cause chronic infection, liver disease, cirrhosis,
and even hepatocellular carcinoma (HCC) in the long
term. Chronic hepatitis B and C infections are the
most important causes of HCC, and these two viruses
constitute the majority of cases (80%) worldwide.
Although hepatitis A, B, C, D, and E viruses all cause
liver disease, they differ in important ways, such as
their transmission patterns, the severity of the disease,
geographic distribution, and prevention. While
hepatitis A and hepatitis E viruses are common in
countries with poor sanitation conditions in the world,
hepatitis B and C are seen all over the world, being
more common in some parts of Africa, Asia, and
South America. It is estimated that 325 million people
worldwide are living with hepatitis B and/or C, and
that most are without access to diagnosis and
treatment. Hepatitis A and E viruses are mainly
transmitted by the fecal–oral route, while the hepatitis
B, C, and D viruses are mainly transmitted by the
parenteral route. For the hepatitis B virus, perinatal
transmission and horizontal transmission (exposure to
infected blood) are important transmission routes,
while needle stick injury, exposure to infected blood
and body fluids, and sexual transmission are other
transmission routes. The hepatitis C virus, on the
other hand, spreads via blood and injected-drug use
through the sharing of injection equipment. While
there is a preventive vaccine for hepatitis A, B, and E
(the hepatitis E vaccine is used in China), a
preventive vaccine has not yet been developed for the
hepatitis C virus. Although powerful treatment
protocols have been developed and are in use for the
hepatitis B and C viruses, which are associated with
chronic diseases, access to treatment is easier in
developed countries, but a large proportion of
infected people is deprived of access to treatment.
Ebola:
There are six genera and 11 species in the Filoviridae
family; one species in the Marburgvirus genus in this
family (Marburg marburgvirus) and four species in
the Ebolavirus genus are associated with human
infection. The Ebolavirus species isolated on the
African continent, namely, the Bundibugyo Ebola
virus, the Sudan Ebola virus, and the Zaire Ebola
virus cause outbreaks with high mortality in humans,
but Taï Forest Ebola virus infections are rare.
Although there are serological data on human
infections for Reston Ebola virus, another species first
isolated in macaques in the Philippines, human–
human transmission has not been demonstrated.
Ebola virus disease (EVD) is an acute severe illness
with a high mortality rate caused by pathogenic Ebola
virus strains. The mortality rate has ranged from 25%
to 90% in various outbreaks of the disease over 40
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years. The Ebola virus was first identified in 1976 in
Zaire (now the Democratic Republic of the Congo
(DRC)) and South Sudan during two concurrent
outbreaks. In these epidemics, a total of 602 people
were infected with Ebola virus and the mortality rate
was found to be 71.59%. On March 23, 2014, the
West African epidemic broke out, which represented
the first global threat posed by Ebola virus. A few
months later, the World Health Organization (WHO)
stated that this epidemic was an international ‘public
health emergency.’ In the biggest Ebola virus
outbreak, 28603 EVD cases were reported with a
mortality rate of 39.5%. Although Ebola virus
infections are only common in West Africa, the virus
is classified as a category A pathogen that could be
abused as a bioterrorism agent due to its potential to
spread globally. Ebola virus infections can be
transmitted in the following ways: via the contact of
infected organisms with tissue, blood, and other body
fluids, via contaminated materials or medical devices,
and during unhygienic practices (such as cutting up a
chimpanzee for food or traditional burial practices).
The Ebola virus is classified at level 4 in the biosafety
risk group; when working with it in the laboratory,
facilities and equipment that provide the highest level
of biosecurity are required. The laboratory diagnosis
of Ebola virus can be accomplished by examining
blood, body fluids, and other clinical specimens from
animals and humans. Enzyme-linked immunosorbent
(ELISA) tests, antigen detection tests, serum
neutralization tests, and reverse-transcription PCR
can be used to examine these samples. IgM and IgG
antibodies can be measured using
immunofluorescence antibody (IFA), or
immunoassay-based tests.
Figure: E-bola virus
Zika
Zika virus is one of the 53 different species of the
Flaviviridae family in the Flavivirusgenus. It was first
discovered in the Zika forest (Kampala, Uganda) in
1947.The majority of Zika virus infections have a
subclinical course, but some patients may experience
clinical symptoms similar to those of other arboviral
infections. Eighty percent of infected people are
asymptomatic. The disease symptoms are usually
mild and are characterized by the acute onset of mild
fever, maculopapularrash, arthralgia, and non-
purulent conjunctivitis. Until 2015, no deaths were
attributed to Zika virus infections. Three deaths
attributed to the Zika virus were first reported in
Brazil, including the death of a newborn with
microcephaly, on 28November 2015. Also, various
neurological (Guillain Barré syndrome,
meningoencephalitis) and autoimmune
(thrombocytopenic purpura, leukopenia)
complications have been reported in Zika-virus-
infected people. While the Zika virushas attracted
great attention in recent years due to the epidemics it
causes and it spossible relationship with serious
autoimmune–neurological diseases, it was identified
as an urgent public health problem of international
importance by the WHO in February 2016.
Norovirus
Norwalk virus, the only species in the Norovirus
genus, is a non-enveloped, positive sense RNA virus
classified as being in the Caliciviridae family.
Another species associated with human infection in
the Caliciviridae family is the Sapporo virus, theonly
species in the Sapovirus genus. Both viruses generally
induce self-limiting gastroenteritis. Long-term illness
is seen in immunocom promised individuals.
Vomiting is a consistent and remarkable symptom;
other symptoms may include nausea, diarrhea,
abdominal cramping, fever, and malaise. Norwalk
virus causes a brief but unpleasant illness, also known
as stomach flu, viral gastroenteritis, and winter
vomiting.
Figure: E-bola virus
Influenza
Viruses in the Orthomyxoviridae family are
enveloped and have single-stranded segmented RNA
genomes. This family includes viruses that can be
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transmitted by respiration, direct contact, water, or
ticks. Orthomyxoviruses can cause infection in
humans, birds, many mammal species, and fish. The
most medically important viruses in this family are
the influenza virus species. These viruses (influenza
viruses A, B, and C) are associated with respiratory
tract infections that can lead to serious clinical
consequences in humans. Influenza viruses canlead to
seasonal epidemics and sometimes pandemics
(influenza A). Throughout history, influenza A
pandemics have been blamed for the deaths of tens of
millions of people. Birds are the main reservoir of
influenza A viruses, and humans and many animal
species (such as pigs, horses, seals, whales, and mink)
are affected by the virus. Very virulent or pandemic
reassortant strains may arise when influenza A
viruses that cause infections in different species cross
the species barrier. Seasonal influenza is an acute
respiratory infection caused by influenza viruses
circulating around the world. There are four types of
seasonal influenza virus: influenza viruses A, B, C,
and D. Influenza A and B viruses circulate around the
world and are associated with seasonal epidemic
diseases. Some influenza A viruses can cause a
pandemic, usually at intervals of 20–30 years. An
influenza virus pandemic occurs when a new strain
circulates among humans, since most people are not
immune to this new virus.
Discussion:
The early and rapid identification of viruses that are
emerging, have epidemic potential, cause permanent
damage, or pose a biosecurity risk is critical. These
risks are increasing day by day. It is estimated that
60%–80% of newly emerging or re-emerging viruses
are zoonotic (animal-borne) viruses. Any event that
increases the likelihood of zoonotic viruses being
transmitted to humans plays a role in the spread of
these infections. The coexistence of different animal
species in wet markets and the increase in the
frequency of contact with them, the establishment of
settlements in the habitats of animals, the increase in
the frequency of working with different animal
species in laboratories (by which we do not mean
biological warfare studies but strictly normal
scientific studies), climate change (mosquito
movements) and the large increase in the international
mobility of people (transport by plane, tourism,
international sports events, commercial activities, and
educational travel) are the most important reasons.
However, viruses can also be useful tools.
Conclusion:
Viruses can be used as vectors for therapeutic
purposes and in vaccine studies, to combat other
viruses or bacterial infections resistant to antibiotics,
such as bacteriophages. Viruses can function like a
small hand with which we can touch cells at the
electron-microscope scale if used for good purposes;
conversely, they have been used maliciously in the
past by people who want to destroy humanity and are
likely to be so used in the future. In the future, viral
engineering studies may need to be subjected to
worldwide inspection for reasons of of national and
global security.
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