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Other Names:
● Salmonella typhi
  ● Enteric Fever
 ● Eberth Disease
Signs and Symptoms
headache           Nausea, vomiting, diarrhea
Chilly sensation
                   Coma vigil       fever
   sordes
                   Subsultus tendinum

                      Rose Patches*
                    Ladder-Like Fever
                         Megaly
Pathophysiology
PREDISPOSING FACTORS:        PRECIPITATING FACTORS:
         age                  Improper food handling
                                  Contamination
                                   Poor hygiene
                                Overcrowded areas
Ingestionof food or water
   contaminated with
    Salmonella typhi



   Bacteria adheres/
      invades GIT           Enters distal ileum (Peyer
                                    Patches)
Induces host macrophage
               to attract more
                macrophages



            Enters ducts then diff.
          Organs (liver, spleen, bone
           marrow, lymph nodes)         Megaly

Ladder-
  like      Continuous to multiply
 fever            (1 000 000)
Induces apoptosis of
                  macrophages, leaking to
                  blood stream and to the
                        entire body



                       TYPHOID FEVER



                                The bacteria that remained
The bacteria that doesn’t      present in the system of host
reinfect the host is shed        pauses and continuous to
      into the stool            multiply making the host a
                                           carrier
Complications:
   hemorrhage
   perforation
 typhoid spine or
      neuritis
early heart failure
    septicemia
Reiter’s syndrome
DIAGNOSTIC PROCEDURE:
       Typhidot*
         ELISA
         Widal
      Rectal swab
  PHARMACOTHERAPY:
    Chlorampenicol*
       Ampicillin
     Ciprofloxacin
NURSING MANAGEMENT:
Maintain or restore fluid and electrolyte
              imbalance.
         Monitor patient’s v/s.
      Prevent from further injury.
    Good hygiene and mouth care.
 Cooling measures during febrile state.
       WOF intestinal bleeding.
PREVENTION AND CONTROL:
     Sanitary and proper disposal.
  Proper supervision of food handlers.
            Enteric Isolation.
Adequate protection and provision of safe
         drinking water supply.
 Reporting of case to health authorities.

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Typhoid Fever

  • 1.
  • 2. Other Names: ● Salmonella typhi ● Enteric Fever ● Eberth Disease
  • 3. Signs and Symptoms headache Nausea, vomiting, diarrhea Chilly sensation Coma vigil fever sordes Subsultus tendinum Rose Patches* Ladder-Like Fever Megaly
  • 4. Pathophysiology PREDISPOSING FACTORS: PRECIPITATING FACTORS: age Improper food handling Contamination Poor hygiene Overcrowded areas Ingestionof food or water contaminated with Salmonella typhi Bacteria adheres/ invades GIT Enters distal ileum (Peyer Patches)
  • 5. Induces host macrophage to attract more macrophages Enters ducts then diff. Organs (liver, spleen, bone marrow, lymph nodes) Megaly Ladder- like Continuous to multiply fever (1 000 000)
  • 6. Induces apoptosis of macrophages, leaking to blood stream and to the entire body TYPHOID FEVER The bacteria that remained The bacteria that doesn’t present in the system of host reinfect the host is shed pauses and continuous to into the stool multiply making the host a carrier
  • 7. Complications: hemorrhage perforation typhoid spine or neuritis early heart failure septicemia Reiter’s syndrome
  • 8. DIAGNOSTIC PROCEDURE: Typhidot* ELISA Widal Rectal swab PHARMACOTHERAPY: Chlorampenicol* Ampicillin Ciprofloxacin
  • 9. NURSING MANAGEMENT: Maintain or restore fluid and electrolyte imbalance. Monitor patient’s v/s. Prevent from further injury. Good hygiene and mouth care. Cooling measures during febrile state. WOF intestinal bleeding.
  • 10. PREVENTION AND CONTROL: Sanitary and proper disposal. Proper supervision of food handlers. Enteric Isolation. Adequate protection and provision of safe drinking water supply. Reporting of case to health authorities.