TYPE 2 DIABETES TYPE 2 DIABETES 2 Type 2 Diabetes Student Name Date school Type 2 Diabetes Introduction Diabetes is a multifaceted disease that affects over 29 million individuals in the United States although most of them are not aware they are sick. The prevalence of diagnosed diabetes is higher among certain minorities such as Alaska Natives, American Indians, Hispanics, Asian Americans and non-Hispanic Black. Its reduces muscle, liver and adipose tissue insulin sensitivity to as well as a decrease pancreatic b-cell function leading which can impair insulin secretion. Diabetes mellitus (DM) can be in form of Type 1 DM, gestation DM, type 2 DM, Pre-DM or medication-induced DM while all bear high levels of blood glucose. Lately, new antidiabetic medications have been adopted for the treatment of T2DM, including dipeptidyl peptidase-4 (DPP-4) inhibitors, glucagon-like peptide 1(GLP-1) receptor agonists, anamylin analogue, and sodium-glucose cotransporter 2 (SGLT2) inhibitors. Of all cases of diabetes, 90% - 95% is accounted by type 2 DM (Olokoba, Obateru & Olokoba, 2012). It is characterized by the body failing to use insulin properly because of the relative deficiency in insulin or insulin resistance. Failure to manage type 2 diabetes appropriately can cause grave complications such as neuropathy, retinopathy and cardiovascular diseases. . Problem Diabetes Mellitus type 2 has become an epidemic in the adult population and managing the glucose levels has become a serious problem with close to 285 million people worldwide affected (International Diabetes Federation. 2011). The number of Americans people affected by type 2 diabetes mellitus has continued to grow by 1.9 million cases every year. The problem has been rampant on older people in the United States who account for 10.9 million cases. Among the factors identified as drivers of type 2DM epidemic is physical inactivity, increased age of the U.S. population, increase in the sub-populations prone to diabetes and obesity epidemic. The cost of type 2DM is enormous and in 2012, approximately $176 billion was used in direct medical costs and $69 billion in lost due to lack of productivity. Review of the Literature Author Article Title Describe Relevance to the Problem Statement 1. SLO #1: Discuss various research designs Lew, K. N., & Wick, A. Pharmacotherapy of Type 2 Diabetes Mellitus: Navigating Current and New Therapies Descriptive, correlational and review research designs. The three forenamed research designs were used in the article. 2. SLO #2: Compare and contrast select research designs Espeland et al. Intensive Weight Loss Intervention in Older Individuals: Results from the Action for Health in Diabetes Type 2 Diabetes Mellitus Trial A Randomized controlled clinical trial design Research was done on individuals to determine the impact o ...