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The document provides 12 steps for developing an effective first draft of a manuscript. It recommends consolidating all necessary information, targeting a specific journal, and starting to write without worrying about grammar or punctuation. The key steps are to write quickly to keep the flow, write in your own voice, avoid editing as you write, keep to the outline plan, write each section separately, put the draft aside for a day, then revise it several times with a focus on clarity and brevity while maintaining consistency.

