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eloy.moral.santamarina@sergas.es
COMPLEXO HOSPITALARIO DE PONTEVEDRA
Tratamiento Laparoscópico
de la patología del
COMPARTIMENTO MEDIO y ANTERIOR
( PROMONTOPEXIA Y REPARACIÓN PARAVAGINAL)
PROLAPSO DE ÓRGANOS PÉLVICOSPROLAPSO DE ÓRGANOS PÉLVICOS
VÍA ABDOMINALVÍA VAGINAL
ÚTERO / CÉRVIX / CÚPULA
PARED ANTERIOR Y POSTERIOR
DEFECTOS PARAVAGINALES
HIPERMOVILIDAD URETRAL
REPARACIÓN CLÁSICA
MATERIALES PROTÉSICOS
QUÉ OPERAMOS
CÓMO
CARACTERÍSTICAS
PRIMERA ELECCIÓN
MUY EFICAZ Y POCO INVASIVA
BUENA RECUPERACIÓN
PERMITE TRATAR MÚLTIPLES DEFECTOS
NO SIEMPRE MANTIENE BUENA FUNCIÓN COITAL
Prolapso ÚTERO/ CÚPULA
HIPERMOVILIDAD URETRAL
DEFECTOS PARAVAGINALES
ENTEROCELES
PREVENCIÓN ENTEROCELE
REPARACIÓN CLÁSICA
MATERIALES PROTÉSICOS
QUÉ OPERAMOS
CÓMO
CARACTERÍSTICAS
SOBRE TODO PARA DEFECTOS APICALES
MANTIENE LONGITUD DE VAGINA
MENOS DISPAREUNIA
SIMILAR EFICACIA
pero…
+ COMPLICACIONES y PEOR RECUPERACIÓN
REPRODUCE LA CIRUGÍA Y REDUCE LA MORBILIDAD DE LA VÍA ABIERTA
- NO SE ABRE VAGINA
- PROCEDIMIENTO ABDOMINAL CERRADO
IGUALA O MEJORA LA EFICACIA DE LA VIA ABDOMINAL.
MEJOR RECUPERACIÓN DE TODAS LAS VÍAS (↓ estancia, menos sangrado, < dolor y recuperación )
NO ACORTA VAGINA ELECCIÓN SI DESEA MANTENER FUNCIÓN COITAL
< TASA DE INFECCIÓN
PROLAPSO DE ÓRGANOS PÉLVICOS
VÍA ABDOMINALVÍA VAGINAL
VÍA LAPAROSCÓPICA
HT Laparoscópica 1989 Reich
Burch Laparoscópico1991
Colposacropéxia 1994 Nezhat
Colposacropexia 1957 Savage
Colposuspensión 1962 Burch
HISTEROSACROPÉXIAS / CERVICOSACROPÉXIA
COLPOSACROPÉXIA (1957 Savage )
PECTOPEXIA / POPS
REPARACIÓN PARAVAGINAL
COLPOSUSPENSIÓN ( 1962 Burch)
SUSPENSIÓN A ÚTERO-SACROS
REPARACIÓN ENTEROCELE
¿ QUÉ OPERAMOS ACTUALMENTE ?
PROLAPSO DE ÓRGANOS PÉLVICOS
VÍA LAPAROSCÓPICA
ENCUESTA SECCIÓN DE SUELO PÉLVICO DE LA SEGO 2012
TRATAMIENTO DEL PROLAPSO DE CÚPULA VAGINAL
43,5 %
Mallas
Mallas
Vaginales 25,2 %
Colpectomía-Cleisis
PROMONTOPÉXIA
Laparoscópica
7,8 %
Colpoespinofijación
(Richter)
8,5 %
43,5 %
SACROPÉXIA
Abierta
LIMITACIONES de la LAPAROSCOPIA
( cada vez menos…)
- Historia de múltiples cirugías abdominales o EIP.
- Patología que contraindique anestesia general e
insuflación abdominal.
- Abordajes previos para cirugia del prolapso.
- IMC muy altos
- Limitaciones del cirujano (sutura, nudos).
INTERVENCIONES
LAPAROSCÓPICAS
• COMPARTIMENTO ANTERIOR
Reparación de defecto paravaginal
Colposuspensión Burch para IUE
Colposacropexia
POPS (cinta de malla subperitoneal parietal)
Pectopexia ( fijación con malla a lig.ileopectíneo)
• COMPARTIMENTO APICAL
Mc Call Laparoscopico (fijación a Lig.US)
Colposacropexia
Histeropromontopexia
POPS
Pectopexia
DEFECTOS DEL COMPARTIMENTO
ANTERIOR
Desinserción LATERAL de la fascia pubocervical +++
DeLancey, AJOG 187:93;2002
Defecto paravaginal
Defecto paravaginal
Es posible corregir el cistocele por LPS (reparación paravaginal).
Curación (POP-Q: Ba ≤0): 96% (12 m); 76% (5 a) .
O´Shea, Behnia-Willison, et al. Laparoscopic paravaginal repair. Objective outcomes. J Minim Invasive
Gynecol 2012;19: S61.
PERO …
No existe evidencia que apoye la superioridad de los resultados
anatómicos con respecto a cirugía vaginal clásica o mallas
Karram. Int Urogynecol J 2004; 15:1-2.
Frick, Paraiso. Clin Obstet Gynecol 2009; 52:390-400.
Shippey. Int Urogynecol J 2010; 21:279-83.
REPARACIÓN PARAVAGINAL LAPAROSCÓPICA
DEFECTOS DEL COMPARTIMENTO ANTERIOR
DEFECTOS DEL COMPARTIMENTO
ANTERIOR
We found no difference concerning symptoms, quality of life, improvement (PFDI-20, PFIQ-7, ICIQ-SF, EQ5D
Barber score [3]. There was no difference in the rate of patients still sexually active at one year (LSC = 87.2% v
but the rate of dyspareunia was lower after LSC (14.1%) than after VRM (29.5%, p = 0.031), as was the r
worsening of dyspareunia (8.5% vs. 19.7%, p = 0.061). At 12 months, there was a significant difference in favour
the Obstructed Defecation Score (ODS) at 12 months (see Table), however the difference was no longer signific
for posterior mesh placement (p=0.167).
Outcome Measure LSC group
n/N (%)
VRM group
n/N (%)
OR [95% CI]
No. with Point Ba < -10 mm 73/127 (57.5) 75/127 (59.1) 0.94 [0.57-1.54]
No. with Point C < -10 mm 125/127 (98.4) 114/126 (90.5) 6.58 [1.44 - 30.03]
No. with Point Bp < -10 mm 106/127 (83.5) 102/127 (80.3) 1.24 [0.65-2.35]
No. Prolapse stage 0 or 1 59/127 (53.5) 59/127 (53.5) 1.00 (0.61 - 1.64)
Barber score 109/127 (85.8) 112/127 (88.2) 0.81 (0.39 – 1.69)
No. with Symptom of vaginal
bulge
118/128 (92.2) 122/127 (96.1) 0.48 (0.16 - 1.46)
No. of patients still sexually
active
67/78 (87.2) 59/67 (88.1) 0.92 (0.34 - 2.49)
No. with Dyspareunia 7/68(10.3) 16/59 (27.1) 0.308 (0.12 – 0.81)
No. with Improvement (PGI-I) 117/128 (91.4) 111/127 (87.4) 1.53 (0.68 – 3.45)
Mean (95% CI) mean (95% CI) mean difference [95%
CI]*
PFDI score 25.0 (20.0-29.9) 26.1 (21.2 -31.1) -1.14 (-8.16 - 5.88)
POPDI subscale 5.7 (3.9- 7.6) 6.5 (4.7- 8.4) -0.80 (-3.41 - 1.81)
DDI-8 subscale 11.1 (9.2 - 13.1) 9.2 (7.3 - 11.2) 1.92 (-0.82 - 4.67)
UDI subscale 8.3 (5.9 - 10.6) 10.4 (8.1 - 12.8) -2.15 (-5.49 - 1.19)
PFIQ-7 score 6.1 (2.9- 9.3) 9.8 (6.6 – 13.1) -3.74 (-8.29 – 0.82)
EuroQoL5D scale 82.4 (76.7 - 85.1) 81.9 (79.2 -
84.7)
0.48 (-3.37 - 4.34)
FSFI score for sexually active
patients
27.4 (26.1 - 28.8) 26.8 (25.4 -
28.2)
0.63 (-1.36 - 2.61)
ICIQ-UI SF score (0-21) 1.7 (1.1- 2.3) 2.2 (1.6 - 2.8) -0.48 (-1.33 - 0.36)
ODS score 4.8 (4.2 to 5.5) 3.9 (3.2 to 4.6) 0.94 (0.01 to 1.89)
Tratamiento del CISTOCELE
Histeropéxia Laparoscópica vs. Mallas vaginales
376
Fauconnier A1, Cosson M2, Debodinance P3, Bader G4, Youssef Azer Akladios C5, Salet-Lizee D6, Campagne-
Loiseau S7, Deffieux X8, Ferry P9, de Tayrac R10, Fritel X11, Lucot J12
1. CHI Poissy-Saint-Germain, Poissy, EA 7285 RISCQ, Université Versailles Saint-Quentin, France, 2. Univ. Hosp.
Jeanne de Flandre, Lille, France,, 3. Centre Hosp. de Dunkerque, Dunkerque, France, 4. CHI Poissy-Saint-Germain,
Poissy, France, 5. Ho^pital de Hautepierre, Strasbourg, France, 6. Groupe Hosp. Diaconesses Croix St-Simon, Paris,
France, 7. CHU Estaing, Clermont-Ferrand, France, 8. Hôpital Antoine Béclère, Clamart, France, 9. La Rochelle
Hosp., La Rochelle, France, 10. Caremeau Univ. Hosp., Nîmes, France, 11. CHU de Poitiers, Poitiers, France, 12.
Univ. Hosp. Jeanne de Flandre, Lille, France
ANATOMICAL AND FUNCTIONAL OUTCOMES OF VAGINAL MESH SURGERY VERSUS
LAPAROSCOPIC SACROCOLPOHYSTEROPEXY FOR CYSTOCELE REPAIR: 12-MONTH
RESULTS OF THE PROSPERE (PROSTHETIC PELVIC FLOOR REPAIR) RANDOMISED
CONTROLLED TRIAL.
Hypothesis / aims of study
Cystocele is a frequent and sometimes disabling type of pelvic organ prolapse (POP) in women. Sacrocolpohysteropexy using
synthetic mesh is considered as the surgical gold standard, and the laparoscopic approach (LSC) has supplanted the open
abdominal route because it offers the same anatomical results with lower morbidity. The use of mesh during vaginal repair (VRM)
may have many advantages: easiness to perform, shorter operative time and recovery [1]. At the present time only one RCT has
compared LSC and VRM: the results were in favour of LSC in terms of anatomical results, but it was a single-site study with only
2 surgeons (consultant and fellow urogynaecologist) that may limit the generalisability of the findings [2]. Both the French HAS
(Haute Autorité de Santé) and the UK Department of Health have highlighted the need for a comparative study to properly evaluate
the risk and benefit ratio of surgery including mesh procedures. A French national multicentre randomised study, including centres
with experience of both the vaginal and laparoscopic approach, was designed for comparison of the safety, functional and
anatomical results of these approaches. We present here the results of functional and anatomical outcomes at one year.
Study design, materials and methods
376
Fauconnier A1, Cosson M2, Debodinance P3, Bader G4, Youssef Azer Akladios C5, Salet-Lizee D6, Campagne-
Loiseau S7, Deffieux X8, Ferry P9, de Tayrac R10, Fritel X11, Lucot J12
1. CHI Poissy-Saint-Germain, Poissy, EA 7285 RISCQ, Université Versailles Saint-Quentin, France, 2. Univ. Hosp.
Jeanne de Flandre, Lille, France,, 3. Centre Hosp. de Dunkerque, Dunkerque, France, 4. CHI Poissy-Saint-Germain,
Poissy, France, 5. Ho^pital de Hautepierre, Strasbourg, France, 6. Groupe Hosp. Diaconesses Croix St-Simon, Paris,
France, 7. CHU Estaing, Clermont-Ferrand, France, 8. Hôpital Antoine Béclère, Clamart, France, 9. La Rochelle
Hosp., La Rochelle, France, 10. Caremeau Univ. Hosp., Nîmes, France, 11. CHU de Poitiers, Poitiers, France, 12.
Univ. Hosp. Jeanne de Flandre, Lille, France
ANATOMICAL AND FUNCTIONAL OUTCOMES OF VAGINAL MESH SURGERY VERSUS
LAPAROSCOPIC SACROCOLPOHYSTEROPEXY FOR CYSTOCELE REPAIR: 12-MONTH
RESULTS OF THE PROSPERE (PROSTHETIC PELVIC FLOOR REPAIR) RANDOMISED
CONTROLLED TRIAL.
Hypothesis / aims of study
Cystocele is a frequent and sometimes disabling type of pelvic organ prolapse (POP) in women. Sacrocolpohysteropexy using
synthetic mesh is considered as the surgical gold standard, and the laparoscopic approach (LSC) has supplanted the open
abdominal route because it offers the same anatomical results with lower morbidity. The use of mesh during vaginal repair (VRM)
may have many advantages: easiness to perform, shorter operative time and recovery [1]. At the present time only one RCT has
compared LSC and VRM: the results were in favour of LSC in terms of anatomical results, but it was a single-site study with only
2 surgeons (consultant and fellow urogynaecologist) that may limit the generalisability of the findings [2]. Both the French HAS
(Haute Autorité de Santé) and the UK Department of Health have highlighted the need for a comparative study to properly evaluate
the risk and benefit ratio of surgery including mesh procedures. A French national multicentre randomised study, including centres
with experience of both the vaginal and laparoscopic approach, was designed for comparison of the safety, functional and
anatomical results of these approaches. We present here the results of functional and anatomical outcomes at one year.
Study design, materials and methods
PROSPERE RCT is a randomised multicentre controlled trial conducted in 12 participating French hospital referral centres for
pelvic reconstructive surgery. Inclusion criteria were: patients aged 45 to 75 years old, with cystocele ≥ stage 2 of the POP-Q
classification. Exclusion criteria were a previous surgical POP repair, and inability or contra-indication for one or the other
technique.
Both LSC and VRM surgery were standardised using a consensus Delphi method. For LSC, the mesh had to be fixed to the
promontory by stitches; peritonisation of the mesh was mandatory. For vaginal repair, the mesh had to be suspended by four
Tratamiento del CISTOCELE
Histeropéxia Laparoscópica vs. Mallas vaginales
Mejoría funcional y de CdV significativa tras cirugía
sin diferencias entre mallas vaginales/laparoscopia
(excepto menos dispareunia en laparoscopia)
la laparoscopia debería favorecerse en pacientes sexualmente activas
376
Fauconnier A1, Cosson M2, Debodinance P3, Bader G4, Youssef Azer Akladios C5, Salet-Lizee D6, Campagne-
Loiseau S7, Deffieux X8, Ferry P9, de Tayrac R10, Fritel X11, Lucot J12
1. CHI Poissy-Saint-Germain, Poissy, EA 7285 RISCQ, Université Versailles Saint-Quentin, France, 2. Univ. Hosp.
Jeanne de Flandre, Lille, France,, 3. Centre Hosp. de Dunkerque, Dunkerque, France, 4. CHI Poissy-Saint-Germain,
Poissy, France, 5. Ho^pital de Hautepierre, Strasbourg, France, 6. Groupe Hosp. Diaconesses Croix St-Simon, Paris,
France, 7. CHU Estaing, Clermont-Ferrand, France, 8. Hôpital Antoine Béclère, Clamart, France, 9. La Rochelle
Hosp., La Rochelle, France, 10. Caremeau Univ. Hosp., Nîmes, France, 11. CHU de Poitiers, Poitiers, France, 12.
Univ. Hosp. Jeanne de Flandre, Lille, France
ANATOMICAL AND FUNCTIONAL OUTCOMES OF VAGINAL MESH SURGERY VERSUS
LAPAROSCOPIC SACROCOLPOHYSTEROPEXY FOR CYSTOCELE REPAIR: 12-MONTH
RESULTS OF THE PROSPERE (PROSTHETIC PELVIC FLOOR REPAIR) RANDOMISED
CONTROLLED TRIAL.
Hypothesis / aims of study
Cystocele is a frequent and sometimes disabling type of pelvic organ prolapse (POP) in women. Sacrocolpohysteropexy using
synthetic mesh is considered as the surgical gold standard, and the laparoscopic approach (LSC) has supplanted the open
abdominal route because it offers the same anatomical results with lower morbidity. The use of mesh during vaginal repair (VRM)
may have many advantages: easiness to perform, shorter operative time and recovery [1]. At the present time only one RCT has
compared LSC and VRM: the results were in favour of LSC in terms of anatomical results, but it was a single-site study with only
2 surgeons (consultant and fellow urogynaecologist) that may limit the generalisability of the findings [2]. Both the French HAS
(Haute Autorité de Santé) and the UK Department of Health have highlighted the need for a comparative study to properly evaluate
the risk and benefit ratio of surgery including mesh procedures. A French national multicentre randomised study, including centres
with experience of both the vaginal and laparoscopic approach, was designed for comparison of the safety, functional and
anatomical results of these approaches. We present here the results of functional and anatomical outcomes at one year.
Study design, materials and methods
376
Fauconnier A1, Cosson M2, Debodinance P3, Bader G4, Youssef Azer Akladios C5, Salet-Lizee D6, Campagne-
Loiseau S7, Deffieux X8, Ferry P9, de Tayrac R10, Fritel X11, Lucot J12
1. CHI Poissy-Saint-Germain, Poissy, EA 7285 RISCQ, Université Versailles Saint-Quentin, France, 2. Univ. Hosp.
Jeanne de Flandre, Lille, France,, 3. Centre Hosp. de Dunkerque, Dunkerque, France, 4. CHI Poissy-Saint-Germain,
Poissy, France, 5. Ho^pital de Hautepierre, Strasbourg, France, 6. Groupe Hosp. Diaconesses Croix St-Simon, Paris,
France, 7. CHU Estaing, Clermont-Ferrand, France, 8. Hôpital Antoine Béclère, Clamart, France, 9. La Rochelle
Hosp., La Rochelle, France, 10. Caremeau Univ. Hosp., Nîmes, France, 11. CHU de Poitiers, Poitiers, France, 12.
Univ. Hosp. Jeanne de Flandre, Lille, France
ANATOMICAL AND FUNCTIONAL OUTCOMES OF VAGINAL MESH SURGERY VERSUS
LAPAROSCOPIC SACROCOLPOHYSTEROPEXY FOR CYSTOCELE REPAIR: 12-MONTH
RESULTS OF THE PROSPERE (PROSTHETIC PELVIC FLOOR REPAIR) RANDOMISED
CONTROLLED TRIAL.
Hypothesis / aims of study
Cystocele is a frequent and sometimes disabling type of pelvic organ prolapse (POP) in women. Sacrocolpohysteropexy using
synthetic mesh is considered as the surgical gold standard, and the laparoscopic approach (LSC) has supplanted the open
abdominal route because it offers the same anatomical results with lower morbidity. The use of mesh during vaginal repair (VRM)
may have many advantages: easiness to perform, shorter operative time and recovery [1]. At the present time only one RCT has
compared LSC and VRM: the results were in favour of LSC in terms of anatomical results, but it was a single-site study with only
2 surgeons (consultant and fellow urogynaecologist) that may limit the generalisability of the findings [2]. Both the French HAS
(Haute Autorité de Santé) and the UK Department of Health have highlighted the need for a comparative study to properly evaluate
the risk and benefit ratio of surgery including mesh procedures. A French national multicentre randomised study, including centres
with experience of both the vaginal and laparoscopic approach, was designed for comparison of the safety, functional and
anatomical results of these approaches. We present here the results of functional and anatomical outcomes at one year.
Study design, materials and methods
PROSPERE RCT is a randomised multicentre controlled trial conducted in 12 participating French hospital referral centres for
pelvic reconstructive surgery. Inclusion criteria were: patients aged 45 to 75 years old, with cystocele ≥ stage 2 of the POP-Q
classification. Exclusion criteria were a previous surgical POP repair, and inability or contra-indication for one or the other
technique.
Both LSC and VRM surgery were standardised using a consensus Delphi method. For LSC, the mesh had to be fixed to the
promontory by stitches; peritonisation of the mesh was mandatory. For vaginal repair, the mesh had to be suspended by four
2017
DEFECTO DE COMPARTIMENTO MEDIO . ÚTERO
similar mejoría en síntomas de POP
similares tasas de recurrencia de POP
similares tasas de IUE de novo
Cochrane Databaseof SystematicReviews
Surgery for women with apical vaginal prolapse (Review)
Maher C, Feiner B, Baessler K, Christmann-Schmid C, Haya N, Brown J
Sacral colpopexy has superior outcomes to a variety of vaginal
procedures including sacrospinous colpopexy, uterosacral colpopexy and
transvaginal mesh “
DEFECTO DE COMPARTIMENTO MEDIO . CÚPULA
Lower risk of awareness of prolapse, recurrent prolapse on examination,
repeat surgery for prolapse, postoperative SUI and dyspareunia
2016
Cochrane Databaseof SystematicReviews
Surgery for women with apical vaginal prolapse (Rev
Maher C, Feiner B, Baessler K, Christmann-Schmid C, Haya N, Brown J
Comparativos con mallas vaginales
LPS > tasa de curación subjetiva y objetiva
LPS < morbilidad perioperatoria y tasa de reintervenciones
LSC TVM
Tiempo operatorio 191 +/- 48 101 +/- 31 P=0.001
Complicaciones intra 1.6% 6.5% ND
Hospitalización 4.02 +/- 1.37 5.27 +/- 2.2 ND
Dispareunia de novo 1.6% 13.1% P=0.015
Estreñimiento post 27.8% 6.5% P=0.02
ReIQ complicaciones 8.2% 14.75% ND
ReIQ prolapso 3.3% 4.9% ND
DEFECTO DE COMPARTIMENTO MEDIO . CÚPULA
Maher. Am J Obstet Gynecol 2011
RESULTADOS CSP LAPAROSCOPICA.
EUROPEAN UROLOGY 2014
REVIEW ARTICLE
The treatment of post-hysterectomy vaginal vault prolapse:
a systematic review and meta-analysis
Anne-LotteW. M. Coolen1
&Bich Ngoc Bui1
&VivianeDietz2
&Rui Wang3
&
Aafke P. A. van Montfoort4
&Ben Willem J. Mol3
&Jan-Paul W. R. Roovers5
&
MarliesY. Bongers1 ,4
Received: 13 May 2017 /Accepted: 13 September 2017
# TheAuthor(s) 2017. This articleisan open accesspublication
Abstract
Introduction and hypothesis The treatment of post-
hysterectomy vaginal vault prolapse (VVP) has been investi-
gated in several randomized clinical trials (RCTs), but a sys-
tematic review of the topic is still lacking. The aim of this
study is to comparetheeffectivenessof treatmentsfor VVP.
Methods We performed a systematic review and meta-
analysis of the literature on the treatment of VVP found in
PubMed and Embase. Reference lists of identified relevant
articles were checked for additional articles. A network plot
was constructed to illustrate the geometry of the network of
thetreatmentsincluded. Only RCTsreportingonthetreatment
of VVP were eligible, conditional on a minimum of 30 par-
ticipantswith VVP and afollow-up of at least 6 months.
Results NineRCTsreporting 846 women (rangingfrom95to
168women) met theinclusion criteria. All surgical techniques
wereassociated with good subjectiveresults, and without dif-
ferencesbetween thecompared technique, with theexception
of the comparison of vaginal mesh (VM) vs laparoscopic
sacrocolpopexy (LSC). LSC isassociated with ahigher satis-
faction rate. The anatomical results of the sacrocolpopexy
(laparoscopic, robotic [RSC]. and abdominal [ASC]) are the
best (62–91%), followed by the VM. However, the ranges of
the anatomical outcome of VM were wide (43–97%). The
poorest results are described for the sacrospinal fixation
(SSF; 35–81%), which also correlateswith thehigher reoper-
ation ratefor pelvicorgan prolapse(POP; 5–9%). Thehighest
percentage of complications were reported after ASC (2–
19%), VM (6–29%), and RSC (54%). Mesh exposure was
seen most often after VM (8–21%). The rate of reoperations
carriedout becauseof complications, recurrenceprolapse, and
incontinence of VM was 13–22%. Overall, sacrocolpopexy
reported the best results at follow-up, with an outlier of one
trial reporting thehighest reoperation ratefor POP(11%). The
results of the RSC are too small to makeany conclusion, but
LSC seemsto bepreferable to ASC.
Conclusions A comparison of techniques was difficult be-
cause of heterogeneity; therefore, a network meta-analysis
was not possible. All techniques have proved to beeffective.
The reported differences between the techniques were negli-
gible. Therefore, a standard treatment for VVP could not be
given according to thisreview.
Resultswerepresented at apreviousconference: Poster EUGA,
Amsterdam, theNetherlands
Electronic supplementary material Theonlineversion of thisarticle
(https://doi.org/10.1007/s00192-017-3493-2) containssupplementary
material, which isavailableto authorized users
* Anne-LotteW. M. Coolen
anne_lotte_coolen@hotmail.com
1
Department of Obstetricsand Gynecology, MáximaMedical Centre,
DeRun 4600, 5500 MB Veldhoven, The Netherlands
2
Department of Obstetrics and Gynecology, Catharina Hospital,
Michelangelolaan 2, 5623 EJEindhoven, TheNetherlands
3
RobinsonResearch Institute, AdelaideMedical School,University of
Adelaide, Adelaide, SA, Australia
4
Department of Obstetrics and Gynaecology, Maastricht University,
Grow School for Oncology and Developmental Biology,
Minderbroedersberg 4, 6211 LK Maastricht, TheNetherlands
Int Urogynecol J
https://doi.org/10.1007/s00192-017-3493-2
Int Urogyn J 2017
Revisión Sistemática y Metaanálisis
n: 846 mujeres
Seguimiento > 6 meses
Todas las técnicas dan buenos resultados
( CSP abierta y Lap // Mallas Vaginales // RICHTER)
CSP Lap. mejores resultados
> Satisfacción // < Tasa Reoperaciones
Restauración Anatómica ( 62-91%)
(Mejor CSP  malla vaginal  Richter el peor 35-81%)
Complicaciones 1º CSP abd  Mallas vaginales
RESULTADOS CSP LAPAROSCOPICA.
COMPARACIÓN DIFICIL POR HETEROGENEIDAD
2018
2018
2018
CURVA DE APRENDIZAJE
Hsiao, 2007 220 min reducción Tpo. del 30% tras 10 cx
Claerhout, 2009 206 min reducción Tpo significativa tras 30 cx
Akladios, 2010 237 min reducción Tpo del 25% tras 20 cx
Mustafá, 2012 176 min reducción Tpo del 20% tras 15 cx
Tiempo operatorio (97-276 min)
•( entrenamiento y habilidad con
las suturas ) Akladios, 2010
CURVAS DE APRENDIZAJE
Técnica clásica Clermond-Ferrand
• - Corrección integral de todos los defectos existentes a nivel
de los diferentes compartimentos
• - Previene defectos secundarios a la misma cirugía.
• - Mallas por laparoscopia < complicaciones en comparación
a la vía vaginal.
Mejor visión anatómica
Mejor resolución quirúrgica
Menor sangrado
Wattiez et al. Promontofixation for the treatment of prolapse. Urol Clin North Am 2001
DEFECTO DE COMPARTIMENTO MEDIO . CÚPULA
Preparación del campo pélvico
Suspensión de sigma a pared pélvica
incisión peritoneo cara posterior cúpula
Preparación de accesos laterales pararectales hasta MEA (fasciculo puborectal)
Incisión / disección/ Preparación pared anterior
Incisión / disección/ Preparación pared anterior
Incisión / disección/ Preparación promontorio sacro
Incisión / disección/ Preparación promontorio
Incisión / disección/ Preparación promontorio sacro
Incisión / disección/ Preparación promontorio sacro
Anclaje de sutura irreabsorbible en MEA
Puntos de fijación de “patas” posteriores de la malla en MEA
Puntos de fijación de malla posterior a muscularis vaginal posterior
Puntos de fijación de malla anterior a muscularis vaginal anterior
Punto sobre ligamento sacro anterior en promontorio
Fijación extremo craneal de la malla sobre promontorio ( sutura irreabsorbible)
Peritonización sobre la malla con sutura continua reabsorbible
INTERVENCIONES
LAPAROSCÓPICAS
• COMPARTIMENTO ANTERIOR
Reparación de defecto paravaginal
Colposuspensión Burch para IUE
Colposacropexia
POPS (cinta de malla subperitoneal parietal)
Pectopexia ( fijación con malla a lig.ileopectíneo)
• COMPARTIMENTO MEDIO
Mc Call Laparoscopico (fijación a Lig.US)
Colposacropexia
Histeropromontopexia
POPS
Pectopexia
Fijación a lig. úterosacros útero
Laparoscopic vaginal vault suspension using uterosacral ligaments: a review of 133 cases.
Lin, Phelps, Liu. J Minim Invasive Gynecol, 2005
Colpopexia a lig úterosacros:
133 pacientes con prolapso severo de cúpula.
Tpo seguimiento: 2-7,3 a.
87.2% no recurrencia del prolapso.
Uterosacral colpopexy at the time of vaginal hysterectomy: comparison of laparoscopic and vaginal
approaches. Rardin, Erekson. J Reprod Med 2009.
HT + colpopexia a lig úterosacros:
•N=96. V.VAGINAL (seguimiento medio: 8.8m)
•N=22. V.LAPAROSCÓPICA (seguimiento medio: 10.8m)
< Compromiso ureteral 4.2% vs 0%
< Recurrencia del prolapso sintomático de cúpula 10% vs 0%
Fijación a lig. úterosacros cúpula
Fijación de cúpula vaginal a lig.úterosacros
post Histerectomía total laparoscópica
Laparoscopia vs. Robótica
Paraiso. Laparoscopic compared with Robotic Sacrocolpopexy for Vaginal Prolapse. Obstet Gynecol 2011
Anger. Robotic compared with laparoscopic sacrocolpopexy: a randomized controlled trial. Obstet Gynecol 2014
Barber. Apical prolapse. Int Urogynecol J 2013
> tiempos operatorios
> dolor postoperatorio
> coste económico
NO superioridad en ningún parámetro clínico.
Conclusiones
• El objetivo de la cirugía laparoscópica es reproducir los
resultados de las técnicas abiertas mediante técnicas
mínimamente invasivas
• Adecuada valoración preoperatoria para la elección
de la técnica quirúrgica.
• El tratamiento completo del prolapso genital por vía
laparoscópica es una técnica efectiva y reproducible.
• Curva de aprendizaje y habilidades quirúrgicas (sutura)
LA LAPAROSCOPIA EN PATOLOGÍAS DE SUELO PÉLVICO
….NO ES SENCILLA … PERO TAMPOCO UNANO ES SENCILLA … PERO TAMPOCO UNA “MISIÓN IMPOSIBLE”“MISIÓN IMPOSIBLE”
Tto laparoscopico defecto medio y anterior

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Tto laparoscopico defecto medio y anterior

  • 1. eloy.moral.santamarina@sergas.es COMPLEXO HOSPITALARIO DE PONTEVEDRA Tratamiento Laparoscópico de la patología del COMPARTIMENTO MEDIO y ANTERIOR ( PROMONTOPEXIA Y REPARACIÓN PARAVAGINAL)
  • 2. PROLAPSO DE ÓRGANOS PÉLVICOSPROLAPSO DE ÓRGANOS PÉLVICOS VÍA ABDOMINALVÍA VAGINAL ÚTERO / CÉRVIX / CÚPULA PARED ANTERIOR Y POSTERIOR DEFECTOS PARAVAGINALES HIPERMOVILIDAD URETRAL REPARACIÓN CLÁSICA MATERIALES PROTÉSICOS QUÉ OPERAMOS CÓMO CARACTERÍSTICAS PRIMERA ELECCIÓN MUY EFICAZ Y POCO INVASIVA BUENA RECUPERACIÓN PERMITE TRATAR MÚLTIPLES DEFECTOS NO SIEMPRE MANTIENE BUENA FUNCIÓN COITAL Prolapso ÚTERO/ CÚPULA HIPERMOVILIDAD URETRAL DEFECTOS PARAVAGINALES ENTEROCELES PREVENCIÓN ENTEROCELE REPARACIÓN CLÁSICA MATERIALES PROTÉSICOS QUÉ OPERAMOS CÓMO CARACTERÍSTICAS SOBRE TODO PARA DEFECTOS APICALES MANTIENE LONGITUD DE VAGINA MENOS DISPAREUNIA SIMILAR EFICACIA pero… + COMPLICACIONES y PEOR RECUPERACIÓN
  • 3. REPRODUCE LA CIRUGÍA Y REDUCE LA MORBILIDAD DE LA VÍA ABIERTA - NO SE ABRE VAGINA - PROCEDIMIENTO ABDOMINAL CERRADO IGUALA O MEJORA LA EFICACIA DE LA VIA ABDOMINAL. MEJOR RECUPERACIÓN DE TODAS LAS VÍAS (↓ estancia, menos sangrado, < dolor y recuperación ) NO ACORTA VAGINA ELECCIÓN SI DESEA MANTENER FUNCIÓN COITAL < TASA DE INFECCIÓN PROLAPSO DE ÓRGANOS PÉLVICOS VÍA ABDOMINALVÍA VAGINAL VÍA LAPAROSCÓPICA HT Laparoscópica 1989 Reich Burch Laparoscópico1991 Colposacropéxia 1994 Nezhat Colposacropexia 1957 Savage Colposuspensión 1962 Burch
  • 4. HISTEROSACROPÉXIAS / CERVICOSACROPÉXIA COLPOSACROPÉXIA (1957 Savage ) PECTOPEXIA / POPS REPARACIÓN PARAVAGINAL COLPOSUSPENSIÓN ( 1962 Burch) SUSPENSIÓN A ÚTERO-SACROS REPARACIÓN ENTEROCELE ¿ QUÉ OPERAMOS ACTUALMENTE ? PROLAPSO DE ÓRGANOS PÉLVICOS VÍA LAPAROSCÓPICA
  • 5. ENCUESTA SECCIÓN DE SUELO PÉLVICO DE LA SEGO 2012 TRATAMIENTO DEL PROLAPSO DE CÚPULA VAGINAL 43,5 % Mallas Mallas Vaginales 25,2 % Colpectomía-Cleisis PROMONTOPÉXIA Laparoscópica 7,8 % Colpoespinofijación (Richter) 8,5 % 43,5 % SACROPÉXIA Abierta
  • 6. LIMITACIONES de la LAPAROSCOPIA ( cada vez menos…) - Historia de múltiples cirugías abdominales o EIP. - Patología que contraindique anestesia general e insuflación abdominal. - Abordajes previos para cirugia del prolapso. - IMC muy altos - Limitaciones del cirujano (sutura, nudos).
  • 7. INTERVENCIONES LAPAROSCÓPICAS • COMPARTIMENTO ANTERIOR Reparación de defecto paravaginal Colposuspensión Burch para IUE Colposacropexia POPS (cinta de malla subperitoneal parietal) Pectopexia ( fijación con malla a lig.ileopectíneo) • COMPARTIMENTO APICAL Mc Call Laparoscopico (fijación a Lig.US) Colposacropexia Histeropromontopexia POPS Pectopexia
  • 9. Desinserción LATERAL de la fascia pubocervical +++ DeLancey, AJOG 187:93;2002
  • 11. Defecto paravaginal Es posible corregir el cistocele por LPS (reparación paravaginal). Curación (POP-Q: Ba ≤0): 96% (12 m); 76% (5 a) . O´Shea, Behnia-Willison, et al. Laparoscopic paravaginal repair. Objective outcomes. J Minim Invasive Gynecol 2012;19: S61. PERO … No existe evidencia que apoye la superioridad de los resultados anatómicos con respecto a cirugía vaginal clásica o mallas Karram. Int Urogynecol J 2004; 15:1-2. Frick, Paraiso. Clin Obstet Gynecol 2009; 52:390-400. Shippey. Int Urogynecol J 2010; 21:279-83.
  • 14. We found no difference concerning symptoms, quality of life, improvement (PFDI-20, PFIQ-7, ICIQ-SF, EQ5D Barber score [3]. There was no difference in the rate of patients still sexually active at one year (LSC = 87.2% v but the rate of dyspareunia was lower after LSC (14.1%) than after VRM (29.5%, p = 0.031), as was the r worsening of dyspareunia (8.5% vs. 19.7%, p = 0.061). At 12 months, there was a significant difference in favour the Obstructed Defecation Score (ODS) at 12 months (see Table), however the difference was no longer signific for posterior mesh placement (p=0.167). Outcome Measure LSC group n/N (%) VRM group n/N (%) OR [95% CI] No. with Point Ba < -10 mm 73/127 (57.5) 75/127 (59.1) 0.94 [0.57-1.54] No. with Point C < -10 mm 125/127 (98.4) 114/126 (90.5) 6.58 [1.44 - 30.03] No. with Point Bp < -10 mm 106/127 (83.5) 102/127 (80.3) 1.24 [0.65-2.35] No. Prolapse stage 0 or 1 59/127 (53.5) 59/127 (53.5) 1.00 (0.61 - 1.64) Barber score 109/127 (85.8) 112/127 (88.2) 0.81 (0.39 – 1.69) No. with Symptom of vaginal bulge 118/128 (92.2) 122/127 (96.1) 0.48 (0.16 - 1.46) No. of patients still sexually active 67/78 (87.2) 59/67 (88.1) 0.92 (0.34 - 2.49) No. with Dyspareunia 7/68(10.3) 16/59 (27.1) 0.308 (0.12 – 0.81) No. with Improvement (PGI-I) 117/128 (91.4) 111/127 (87.4) 1.53 (0.68 – 3.45) Mean (95% CI) mean (95% CI) mean difference [95% CI]* PFDI score 25.0 (20.0-29.9) 26.1 (21.2 -31.1) -1.14 (-8.16 - 5.88) POPDI subscale 5.7 (3.9- 7.6) 6.5 (4.7- 8.4) -0.80 (-3.41 - 1.81) DDI-8 subscale 11.1 (9.2 - 13.1) 9.2 (7.3 - 11.2) 1.92 (-0.82 - 4.67) UDI subscale 8.3 (5.9 - 10.6) 10.4 (8.1 - 12.8) -2.15 (-5.49 - 1.19) PFIQ-7 score 6.1 (2.9- 9.3) 9.8 (6.6 – 13.1) -3.74 (-8.29 – 0.82) EuroQoL5D scale 82.4 (76.7 - 85.1) 81.9 (79.2 - 84.7) 0.48 (-3.37 - 4.34) FSFI score for sexually active patients 27.4 (26.1 - 28.8) 26.8 (25.4 - 28.2) 0.63 (-1.36 - 2.61) ICIQ-UI SF score (0-21) 1.7 (1.1- 2.3) 2.2 (1.6 - 2.8) -0.48 (-1.33 - 0.36) ODS score 4.8 (4.2 to 5.5) 3.9 (3.2 to 4.6) 0.94 (0.01 to 1.89) Tratamiento del CISTOCELE Histeropéxia Laparoscópica vs. Mallas vaginales 376 Fauconnier A1, Cosson M2, Debodinance P3, Bader G4, Youssef Azer Akladios C5, Salet-Lizee D6, Campagne- Loiseau S7, Deffieux X8, Ferry P9, de Tayrac R10, Fritel X11, Lucot J12 1. CHI Poissy-Saint-Germain, Poissy, EA 7285 RISCQ, Université Versailles Saint-Quentin, France, 2. Univ. Hosp. Jeanne de Flandre, Lille, France,, 3. Centre Hosp. de Dunkerque, Dunkerque, France, 4. CHI Poissy-Saint-Germain, Poissy, France, 5. Ho^pital de Hautepierre, Strasbourg, France, 6. Groupe Hosp. Diaconesses Croix St-Simon, Paris, France, 7. CHU Estaing, Clermont-Ferrand, France, 8. Hôpital Antoine Béclère, Clamart, France, 9. La Rochelle Hosp., La Rochelle, France, 10. Caremeau Univ. Hosp., Nîmes, France, 11. CHU de Poitiers, Poitiers, France, 12. Univ. Hosp. Jeanne de Flandre, Lille, France ANATOMICAL AND FUNCTIONAL OUTCOMES OF VAGINAL MESH SURGERY VERSUS LAPAROSCOPIC SACROCOLPOHYSTEROPEXY FOR CYSTOCELE REPAIR: 12-MONTH RESULTS OF THE PROSPERE (PROSTHETIC PELVIC FLOOR REPAIR) RANDOMISED CONTROLLED TRIAL. Hypothesis / aims of study Cystocele is a frequent and sometimes disabling type of pelvic organ prolapse (POP) in women. Sacrocolpohysteropexy using synthetic mesh is considered as the surgical gold standard, and the laparoscopic approach (LSC) has supplanted the open abdominal route because it offers the same anatomical results with lower morbidity. The use of mesh during vaginal repair (VRM) may have many advantages: easiness to perform, shorter operative time and recovery [1]. At the present time only one RCT has compared LSC and VRM: the results were in favour of LSC in terms of anatomical results, but it was a single-site study with only 2 surgeons (consultant and fellow urogynaecologist) that may limit the generalisability of the findings [2]. Both the French HAS (Haute Autorité de Santé) and the UK Department of Health have highlighted the need for a comparative study to properly evaluate the risk and benefit ratio of surgery including mesh procedures. A French national multicentre randomised study, including centres with experience of both the vaginal and laparoscopic approach, was designed for comparison of the safety, functional and anatomical results of these approaches. We present here the results of functional and anatomical outcomes at one year. Study design, materials and methods 376 Fauconnier A1, Cosson M2, Debodinance P3, Bader G4, Youssef Azer Akladios C5, Salet-Lizee D6, Campagne- Loiseau S7, Deffieux X8, Ferry P9, de Tayrac R10, Fritel X11, Lucot J12 1. CHI Poissy-Saint-Germain, Poissy, EA 7285 RISCQ, Université Versailles Saint-Quentin, France, 2. Univ. Hosp. Jeanne de Flandre, Lille, France,, 3. Centre Hosp. de Dunkerque, Dunkerque, France, 4. CHI Poissy-Saint-Germain, Poissy, France, 5. Ho^pital de Hautepierre, Strasbourg, France, 6. Groupe Hosp. Diaconesses Croix St-Simon, Paris, France, 7. CHU Estaing, Clermont-Ferrand, France, 8. Hôpital Antoine Béclère, Clamart, France, 9. La Rochelle Hosp., La Rochelle, France, 10. Caremeau Univ. Hosp., Nîmes, France, 11. CHU de Poitiers, Poitiers, France, 12. Univ. Hosp. Jeanne de Flandre, Lille, France ANATOMICAL AND FUNCTIONAL OUTCOMES OF VAGINAL MESH SURGERY VERSUS LAPAROSCOPIC SACROCOLPOHYSTEROPEXY FOR CYSTOCELE REPAIR: 12-MONTH RESULTS OF THE PROSPERE (PROSTHETIC PELVIC FLOOR REPAIR) RANDOMISED CONTROLLED TRIAL. Hypothesis / aims of study Cystocele is a frequent and sometimes disabling type of pelvic organ prolapse (POP) in women. Sacrocolpohysteropexy using synthetic mesh is considered as the surgical gold standard, and the laparoscopic approach (LSC) has supplanted the open abdominal route because it offers the same anatomical results with lower morbidity. The use of mesh during vaginal repair (VRM) may have many advantages: easiness to perform, shorter operative time and recovery [1]. At the present time only one RCT has compared LSC and VRM: the results were in favour of LSC in terms of anatomical results, but it was a single-site study with only 2 surgeons (consultant and fellow urogynaecologist) that may limit the generalisability of the findings [2]. Both the French HAS (Haute Autorité de Santé) and the UK Department of Health have highlighted the need for a comparative study to properly evaluate the risk and benefit ratio of surgery including mesh procedures. A French national multicentre randomised study, including centres with experience of both the vaginal and laparoscopic approach, was designed for comparison of the safety, functional and anatomical results of these approaches. We present here the results of functional and anatomical outcomes at one year. Study design, materials and methods PROSPERE RCT is a randomised multicentre controlled trial conducted in 12 participating French hospital referral centres for pelvic reconstructive surgery. Inclusion criteria were: patients aged 45 to 75 years old, with cystocele ≥ stage 2 of the POP-Q classification. Exclusion criteria were a previous surgical POP repair, and inability or contra-indication for one or the other technique. Both LSC and VRM surgery were standardised using a consensus Delphi method. For LSC, the mesh had to be fixed to the promontory by stitches; peritonisation of the mesh was mandatory. For vaginal repair, the mesh had to be suspended by four
  • 15. Tratamiento del CISTOCELE Histeropéxia Laparoscópica vs. Mallas vaginales Mejoría funcional y de CdV significativa tras cirugía sin diferencias entre mallas vaginales/laparoscopia (excepto menos dispareunia en laparoscopia) la laparoscopia debería favorecerse en pacientes sexualmente activas 376 Fauconnier A1, Cosson M2, Debodinance P3, Bader G4, Youssef Azer Akladios C5, Salet-Lizee D6, Campagne- Loiseau S7, Deffieux X8, Ferry P9, de Tayrac R10, Fritel X11, Lucot J12 1. CHI Poissy-Saint-Germain, Poissy, EA 7285 RISCQ, Université Versailles Saint-Quentin, France, 2. Univ. Hosp. Jeanne de Flandre, Lille, France,, 3. Centre Hosp. de Dunkerque, Dunkerque, France, 4. CHI Poissy-Saint-Germain, Poissy, France, 5. Ho^pital de Hautepierre, Strasbourg, France, 6. Groupe Hosp. Diaconesses Croix St-Simon, Paris, France, 7. CHU Estaing, Clermont-Ferrand, France, 8. Hôpital Antoine Béclère, Clamart, France, 9. La Rochelle Hosp., La Rochelle, France, 10. Caremeau Univ. Hosp., Nîmes, France, 11. CHU de Poitiers, Poitiers, France, 12. Univ. Hosp. Jeanne de Flandre, Lille, France ANATOMICAL AND FUNCTIONAL OUTCOMES OF VAGINAL MESH SURGERY VERSUS LAPAROSCOPIC SACROCOLPOHYSTEROPEXY FOR CYSTOCELE REPAIR: 12-MONTH RESULTS OF THE PROSPERE (PROSTHETIC PELVIC FLOOR REPAIR) RANDOMISED CONTROLLED TRIAL. Hypothesis / aims of study Cystocele is a frequent and sometimes disabling type of pelvic organ prolapse (POP) in women. Sacrocolpohysteropexy using synthetic mesh is considered as the surgical gold standard, and the laparoscopic approach (LSC) has supplanted the open abdominal route because it offers the same anatomical results with lower morbidity. The use of mesh during vaginal repair (VRM) may have many advantages: easiness to perform, shorter operative time and recovery [1]. At the present time only one RCT has compared LSC and VRM: the results were in favour of LSC in terms of anatomical results, but it was a single-site study with only 2 surgeons (consultant and fellow urogynaecologist) that may limit the generalisability of the findings [2]. Both the French HAS (Haute Autorité de Santé) and the UK Department of Health have highlighted the need for a comparative study to properly evaluate the risk and benefit ratio of surgery including mesh procedures. A French national multicentre randomised study, including centres with experience of both the vaginal and laparoscopic approach, was designed for comparison of the safety, functional and anatomical results of these approaches. We present here the results of functional and anatomical outcomes at one year. Study design, materials and methods 376 Fauconnier A1, Cosson M2, Debodinance P3, Bader G4, Youssef Azer Akladios C5, Salet-Lizee D6, Campagne- Loiseau S7, Deffieux X8, Ferry P9, de Tayrac R10, Fritel X11, Lucot J12 1. CHI Poissy-Saint-Germain, Poissy, EA 7285 RISCQ, Université Versailles Saint-Quentin, France, 2. Univ. Hosp. Jeanne de Flandre, Lille, France,, 3. Centre Hosp. de Dunkerque, Dunkerque, France, 4. CHI Poissy-Saint-Germain, Poissy, France, 5. Ho^pital de Hautepierre, Strasbourg, France, 6. Groupe Hosp. Diaconesses Croix St-Simon, Paris, France, 7. CHU Estaing, Clermont-Ferrand, France, 8. Hôpital Antoine Béclère, Clamart, France, 9. La Rochelle Hosp., La Rochelle, France, 10. Caremeau Univ. Hosp., Nîmes, France, 11. CHU de Poitiers, Poitiers, France, 12. Univ. Hosp. Jeanne de Flandre, Lille, France ANATOMICAL AND FUNCTIONAL OUTCOMES OF VAGINAL MESH SURGERY VERSUS LAPAROSCOPIC SACROCOLPOHYSTEROPEXY FOR CYSTOCELE REPAIR: 12-MONTH RESULTS OF THE PROSPERE (PROSTHETIC PELVIC FLOOR REPAIR) RANDOMISED CONTROLLED TRIAL. Hypothesis / aims of study Cystocele is a frequent and sometimes disabling type of pelvic organ prolapse (POP) in women. Sacrocolpohysteropexy using synthetic mesh is considered as the surgical gold standard, and the laparoscopic approach (LSC) has supplanted the open abdominal route because it offers the same anatomical results with lower morbidity. The use of mesh during vaginal repair (VRM) may have many advantages: easiness to perform, shorter operative time and recovery [1]. At the present time only one RCT has compared LSC and VRM: the results were in favour of LSC in terms of anatomical results, but it was a single-site study with only 2 surgeons (consultant and fellow urogynaecologist) that may limit the generalisability of the findings [2]. Both the French HAS (Haute Autorité de Santé) and the UK Department of Health have highlighted the need for a comparative study to properly evaluate the risk and benefit ratio of surgery including mesh procedures. A French national multicentre randomised study, including centres with experience of both the vaginal and laparoscopic approach, was designed for comparison of the safety, functional and anatomical results of these approaches. We present here the results of functional and anatomical outcomes at one year. Study design, materials and methods PROSPERE RCT is a randomised multicentre controlled trial conducted in 12 participating French hospital referral centres for pelvic reconstructive surgery. Inclusion criteria were: patients aged 45 to 75 years old, with cystocele ≥ stage 2 of the POP-Q classification. Exclusion criteria were a previous surgical POP repair, and inability or contra-indication for one or the other technique. Both LSC and VRM surgery were standardised using a consensus Delphi method. For LSC, the mesh had to be fixed to the promontory by stitches; peritonisation of the mesh was mandatory. For vaginal repair, the mesh had to be suspended by four
  • 16. 2017 DEFECTO DE COMPARTIMENTO MEDIO . ÚTERO similar mejoría en síntomas de POP similares tasas de recurrencia de POP similares tasas de IUE de novo
  • 17. Cochrane Databaseof SystematicReviews Surgery for women with apical vaginal prolapse (Review) Maher C, Feiner B, Baessler K, Christmann-Schmid C, Haya N, Brown J Sacral colpopexy has superior outcomes to a variety of vaginal procedures including sacrospinous colpopexy, uterosacral colpopexy and transvaginal mesh “ DEFECTO DE COMPARTIMENTO MEDIO . CÚPULA Lower risk of awareness of prolapse, recurrent prolapse on examination, repeat surgery for prolapse, postoperative SUI and dyspareunia 2016 Cochrane Databaseof SystematicReviews Surgery for women with apical vaginal prolapse (Rev Maher C, Feiner B, Baessler K, Christmann-Schmid C, Haya N, Brown J
  • 18. Comparativos con mallas vaginales LPS > tasa de curación subjetiva y objetiva LPS < morbilidad perioperatoria y tasa de reintervenciones LSC TVM Tiempo operatorio 191 +/- 48 101 +/- 31 P=0.001 Complicaciones intra 1.6% 6.5% ND Hospitalización 4.02 +/- 1.37 5.27 +/- 2.2 ND Dispareunia de novo 1.6% 13.1% P=0.015 Estreñimiento post 27.8% 6.5% P=0.02 ReIQ complicaciones 8.2% 14.75% ND ReIQ prolapso 3.3% 4.9% ND DEFECTO DE COMPARTIMENTO MEDIO . CÚPULA Maher. Am J Obstet Gynecol 2011
  • 20. REVIEW ARTICLE The treatment of post-hysterectomy vaginal vault prolapse: a systematic review and meta-analysis Anne-LotteW. M. Coolen1 &Bich Ngoc Bui1 &VivianeDietz2 &Rui Wang3 & Aafke P. A. van Montfoort4 &Ben Willem J. Mol3 &Jan-Paul W. R. Roovers5 & MarliesY. Bongers1 ,4 Received: 13 May 2017 /Accepted: 13 September 2017 # TheAuthor(s) 2017. This articleisan open accesspublication Abstract Introduction and hypothesis The treatment of post- hysterectomy vaginal vault prolapse (VVP) has been investi- gated in several randomized clinical trials (RCTs), but a sys- tematic review of the topic is still lacking. The aim of this study is to comparetheeffectivenessof treatmentsfor VVP. Methods We performed a systematic review and meta- analysis of the literature on the treatment of VVP found in PubMed and Embase. Reference lists of identified relevant articles were checked for additional articles. A network plot was constructed to illustrate the geometry of the network of thetreatmentsincluded. Only RCTsreportingonthetreatment of VVP were eligible, conditional on a minimum of 30 par- ticipantswith VVP and afollow-up of at least 6 months. Results NineRCTsreporting 846 women (rangingfrom95to 168women) met theinclusion criteria. All surgical techniques wereassociated with good subjectiveresults, and without dif- ferencesbetween thecompared technique, with theexception of the comparison of vaginal mesh (VM) vs laparoscopic sacrocolpopexy (LSC). LSC isassociated with ahigher satis- faction rate. The anatomical results of the sacrocolpopexy (laparoscopic, robotic [RSC]. and abdominal [ASC]) are the best (62–91%), followed by the VM. However, the ranges of the anatomical outcome of VM were wide (43–97%). The poorest results are described for the sacrospinal fixation (SSF; 35–81%), which also correlateswith thehigher reoper- ation ratefor pelvicorgan prolapse(POP; 5–9%). Thehighest percentage of complications were reported after ASC (2– 19%), VM (6–29%), and RSC (54%). Mesh exposure was seen most often after VM (8–21%). The rate of reoperations carriedout becauseof complications, recurrenceprolapse, and incontinence of VM was 13–22%. Overall, sacrocolpopexy reported the best results at follow-up, with an outlier of one trial reporting thehighest reoperation ratefor POP(11%). The results of the RSC are too small to makeany conclusion, but LSC seemsto bepreferable to ASC. Conclusions A comparison of techniques was difficult be- cause of heterogeneity; therefore, a network meta-analysis was not possible. All techniques have proved to beeffective. The reported differences between the techniques were negli- gible. Therefore, a standard treatment for VVP could not be given according to thisreview. Resultswerepresented at apreviousconference: Poster EUGA, Amsterdam, theNetherlands Electronic supplementary material Theonlineversion of thisarticle (https://doi.org/10.1007/s00192-017-3493-2) containssupplementary material, which isavailableto authorized users * Anne-LotteW. M. Coolen anne_lotte_coolen@hotmail.com 1 Department of Obstetricsand Gynecology, MáximaMedical Centre, DeRun 4600, 5500 MB Veldhoven, The Netherlands 2 Department of Obstetrics and Gynecology, Catharina Hospital, Michelangelolaan 2, 5623 EJEindhoven, TheNetherlands 3 RobinsonResearch Institute, AdelaideMedical School,University of Adelaide, Adelaide, SA, Australia 4 Department of Obstetrics and Gynaecology, Maastricht University, Grow School for Oncology and Developmental Biology, Minderbroedersberg 4, 6211 LK Maastricht, TheNetherlands Int Urogynecol J https://doi.org/10.1007/s00192-017-3493-2 Int Urogyn J 2017 Revisión Sistemática y Metaanálisis n: 846 mujeres Seguimiento > 6 meses Todas las técnicas dan buenos resultados ( CSP abierta y Lap // Mallas Vaginales // RICHTER) CSP Lap. mejores resultados > Satisfacción // < Tasa Reoperaciones Restauración Anatómica ( 62-91%) (Mejor CSP  malla vaginal  Richter el peor 35-81%) Complicaciones 1º CSP abd  Mallas vaginales RESULTADOS CSP LAPAROSCOPICA. COMPARACIÓN DIFICIL POR HETEROGENEIDAD
  • 21. 2018
  • 22. 2018
  • 23. 2018
  • 24. CURVA DE APRENDIZAJE Hsiao, 2007 220 min reducción Tpo. del 30% tras 10 cx Claerhout, 2009 206 min reducción Tpo significativa tras 30 cx Akladios, 2010 237 min reducción Tpo del 25% tras 20 cx Mustafá, 2012 176 min reducción Tpo del 20% tras 15 cx Tiempo operatorio (97-276 min) •( entrenamiento y habilidad con las suturas ) Akladios, 2010 CURVAS DE APRENDIZAJE
  • 25. Técnica clásica Clermond-Ferrand • - Corrección integral de todos los defectos existentes a nivel de los diferentes compartimentos • - Previene defectos secundarios a la misma cirugía. • - Mallas por laparoscopia < complicaciones en comparación a la vía vaginal. Mejor visión anatómica Mejor resolución quirúrgica Menor sangrado Wattiez et al. Promontofixation for the treatment of prolapse. Urol Clin North Am 2001 DEFECTO DE COMPARTIMENTO MEDIO . CÚPULA
  • 26. Preparación del campo pélvico Suspensión de sigma a pared pélvica
  • 27. incisión peritoneo cara posterior cúpula
  • 28. Preparación de accesos laterales pararectales hasta MEA (fasciculo puborectal)
  • 29. Incisión / disección/ Preparación pared anterior
  • 30. Incisión / disección/ Preparación pared anterior
  • 31. Incisión / disección/ Preparación promontorio sacro
  • 32. Incisión / disección/ Preparación promontorio
  • 33. Incisión / disección/ Preparación promontorio sacro
  • 34. Incisión / disección/ Preparación promontorio sacro
  • 35. Anclaje de sutura irreabsorbible en MEA
  • 36. Puntos de fijación de “patas” posteriores de la malla en MEA
  • 37. Puntos de fijación de malla posterior a muscularis vaginal posterior
  • 38. Puntos de fijación de malla anterior a muscularis vaginal anterior
  • 39. Punto sobre ligamento sacro anterior en promontorio
  • 40. Fijación extremo craneal de la malla sobre promontorio ( sutura irreabsorbible)
  • 41. Peritonización sobre la malla con sutura continua reabsorbible
  • 42. INTERVENCIONES LAPAROSCÓPICAS • COMPARTIMENTO ANTERIOR Reparación de defecto paravaginal Colposuspensión Burch para IUE Colposacropexia POPS (cinta de malla subperitoneal parietal) Pectopexia ( fijación con malla a lig.ileopectíneo) • COMPARTIMENTO MEDIO Mc Call Laparoscopico (fijación a Lig.US) Colposacropexia Histeropromontopexia POPS Pectopexia
  • 43. Fijación a lig. úterosacros útero
  • 44. Laparoscopic vaginal vault suspension using uterosacral ligaments: a review of 133 cases. Lin, Phelps, Liu. J Minim Invasive Gynecol, 2005 Colpopexia a lig úterosacros: 133 pacientes con prolapso severo de cúpula. Tpo seguimiento: 2-7,3 a. 87.2% no recurrencia del prolapso. Uterosacral colpopexy at the time of vaginal hysterectomy: comparison of laparoscopic and vaginal approaches. Rardin, Erekson. J Reprod Med 2009. HT + colpopexia a lig úterosacros: •N=96. V.VAGINAL (seguimiento medio: 8.8m) •N=22. V.LAPAROSCÓPICA (seguimiento medio: 10.8m) < Compromiso ureteral 4.2% vs 0% < Recurrencia del prolapso sintomático de cúpula 10% vs 0% Fijación a lig. úterosacros cúpula
  • 45. Fijación de cúpula vaginal a lig.úterosacros post Histerectomía total laparoscópica
  • 46. Laparoscopia vs. Robótica Paraiso. Laparoscopic compared with Robotic Sacrocolpopexy for Vaginal Prolapse. Obstet Gynecol 2011 Anger. Robotic compared with laparoscopic sacrocolpopexy: a randomized controlled trial. Obstet Gynecol 2014 Barber. Apical prolapse. Int Urogynecol J 2013 > tiempos operatorios > dolor postoperatorio > coste económico NO superioridad en ningún parámetro clínico.
  • 47. Conclusiones • El objetivo de la cirugía laparoscópica es reproducir los resultados de las técnicas abiertas mediante técnicas mínimamente invasivas • Adecuada valoración preoperatoria para la elección de la técnica quirúrgica. • El tratamiento completo del prolapso genital por vía laparoscópica es una técnica efectiva y reproducible. • Curva de aprendizaje y habilidades quirúrgicas (sutura)
  • 48. LA LAPAROSCOPIA EN PATOLOGÍAS DE SUELO PÉLVICO ….NO ES SENCILLA … PERO TAMPOCO UNANO ES SENCILLA … PERO TAMPOCO UNA “MISIÓN IMPOSIBLE”“MISIÓN IMPOSIBLE”

Editor's Notes

  1. Una valoración prequirúrgica adecuada debe incluir aspectos anatómicos y funcionales del SP. Es importante conocer los defectos responsables del POP en cada paciente individual con el objetivo de alcanzar los mejores resultados anatómicos y determinar el abordaje y la técnica qx más adecuada. -IU: puede desarrollarse de novo o empeorar tras cx del POP debido a q la uretra puede hallarse anatómicamente acodada en pacientes con POP. Tras la cx, una función uretral insuficiente puede debutar con IOE de nueva aparición. La prueba de esfuerzo (tos) con vejiga llena y reducción del POP tiene un valor limitado en el dx de la IOE oculta. Estudio urodinámico. LIMITACIONES LAPAROSCOPIA: -Historia múltiples cx o infecciones pélvicas sugieren la presencia de adherencias. -Laparotomía supraumbilical: considerar laparoscopia abierta (Hasson) o localización alternativa para la Veress (punto de Palmer)=3 cm por debajo del arco costal, en la línea medio-clavicular izquierda -Aspectos técnicos: La sutura laparoscópica es considerada por muchos cirujanos como el aspecto más difícil y tedioso en la cx reconstructiva y ha contribuido significativamente a la lenta adaptación a estas técnicas. Se han desarrollado igualmente técnicas para conseguir nudos seguros: nudos extracorpóreos es la técnica más común, nudos intracorpóreos son obligados cuando se suturan tejidos más delicados debiéndose evitar la tensión al apretar el nudo
  2. La cx laparoscópica para la reparación del POP puede ser dividida en compartimento ANT, APICAL y POST: Es muy importante reparar todas las relajaciones, aún cuando sean menores, pues si no se reconstruye el suelo pélvico globalmente, estos defectos menores se pueden convertir en mayores en el futuro. Habitualmente diversos procedimientos qx son requeridos en cada caso individual ya que es frecuente diagnosticar múltiples defectos del SP que pueden resultar en el prolapso de más de un órgano pélvico.
  3. La corrección laparoscópica del defecto paravaginal es técnicamente factible y puede tener una justificación como procedimiento concominante Sin embargo no existe evidencia suficiente que apoye de forma aislada la reparación de los defectos paravaginales, no existiendo ningún ensayo que compare la reparación de la pared vaginal anterior versus reparación paravaginal abdominal en el tratamiento de cistocele Shippey. Int Urogynecol J 2010;21(3):279-83. Estudio comparativo Colposacropexia abdominal +/- corrección defectos paravaginales. Resultados: Tendencia a una menor tasa de cistocele recurrente en el grupo con corrección defectos paravaginales pero sin alcanzar significancia estadística.
  4. Sólo se han identificado dos estudios comparativos LSC: colposacropexia laparoscópica / TVM: malla vaginal total 1º Estudio RANDOMIZADO con resultados a los 2 años, n= 53 / 55 2º Estudio retrospectivo Bicéntrico (francés), n= 61 / 61
  5. La colposacropexia transabdominal ha demostrado excelentes resultados en la reparación a largo plazo del prolapso severo de cúpula (93-100%), hasta el punto de que es considerada la técnica quirúrgica de referencia para la reparación del prolapso apical. Además de la durabilidad de los resultados, esta técnica permite preservar el eje normal de la vagina gracias al anclaje de la cúpula vaginal a la superficie anterior del sacro, y por otro lado mantiene la máxima profundidad de vagina. Estos aspectos van a ser muy importantes en aquellas mujeres sexualmente activas o en aquellas con vaginas acortadas por otros procedimientos quirúrgicos.
  6. Sólo se han identificado dos estudios comparativos LSC: colposacropexia laparoscópica / TVM: malla vaginal total 1º Estudio RANDOMIZADO con resultados a los 2 años, n= 53 / 55 2º Estudio retrospectivo Bicéntrico (francés), n= 61 / 61
  7. No existen grandes estudios randomizados comparativos entre la técnica abdominal y laparoscópica. Estudios no randomizados y series publicadas para el abordaje laparoscópico establecen tasas de éxito del 75 al 100% con un periodo de seguimiento de 6meses-5años.
  8. La presumible larga duración de la curva de aprendizaje y el temor a exponer a los pacientes a una excesiva morbilidad durante esta curva de aprendizaje contribuye a la lenta adopción de la colposacropexia laparoscópica entre las técnicas habituales para el tratamineto del prolapso genital. Fig. 2. The learning curve. The study population was divided into 8 equal groups of 6 interventions each, classed chronologically (abscissa). Mean duration of surgery for the 6 procedures is given in ordinates. El tiempo operatorio decreció significativamente tras 18-24 intervenciones.
  9. La cx laparoscópica para la reparación del POP puede ser dividida en compartimento ANT, APICAL y POST: Es muy importante reparar todas las relajaciones, aún cuando sean menores, pues si no se reconstruye el suelo pélvico globalmente, estos defectos menores se pueden convertir en mayores en el futuro. Habitualmente diversos procedimientos qx son requeridos en cada caso individual ya que es frecuente diagnosticar múltiples defectos del SP que pueden resultar en el prolapso de más de un órgano pélvico.
  10. Técnica qx: Se identifica la porción proximal del lig.úterosacro a nivel de la espina ciática y se sutura con material irreabsorvible hasta la porción distal del ligamento, cerca de su inserción en segmento uterino inf / cèrvix. Esta reaproximación del ligamento avulsionado restablece el soporte apical (Nivel I) de la vagina proximal en una posición horizontal sobre el plano del elevador. El uréter pélvico deberá ser localizado antes de suturar el lig.úterosacro.
  11. Existen estudios no randomizados y series de casos que han demostrado la eficacia en cuanto a mejoría de síntomas y resultados anatómicos para esta técnica realizada vía laparoscópica en el tratamiento de mujeres con prolapso uterino o de cúpula.
  12. El prolapso de cúpula puede ocurrir dsp de cualquier HT aunque aparece más frecuentemente en aquellas mujeres cuya HT se realizó por prolapso, quizás por una suspensión insuficiente del ápex vaginal tras la HT. En nuestro servicio realizamos de forma sistemática la fijación de cúpula vaginal a ligamentos úterosacros a todas aquellas mujeres sometidas a histerectomia total laparoscópica, independientemente de la indicación quirúrgica, con una intención profiláctica al considerar la cirugía pélvica como un factor de riesgo para un posible prolapso de cúpula.
  13. Aunque la cirugía robótica permite acelerar la curva de aprendizaje de cirujanos menos experimentados no parece ofrecer una clara ventaja en el caso de cirujanos experimentados en laparoscopia avanzada. Teniendo en cuenta los costes adicionales asociados a la robótica en comparación a la laparoscopia convencional se plantean como necesarias futuras investigaciones para discernir cuáles podrían ser las mejores aplicaciones para la robótica en el campo de la patología ginecológica benigna.
  14. Valoración preoperatoria: Es especialmente importante valorar el estado de continencia con la intención de minimizar la IOE de novo tras la cx. Considerar los riesgos individuales para la cx laparoscópica (IQ previas…) El abordaje laparoscópico ofrece una una mejor visión anatómica de la pelvis en comparación al abordaje laparotómico o vaginal. Los beneficios adicionales de la cx reconstructiva por vía laparoscópica incluye menor dolor postoperatorio y estancia hospitalaria con una más rápida reincorporación a las actividades habituales.