Depression affects millions of people each year across all ages and demographics. Some of the top 10 signs of depression include persistent feelings of sadness, lack of energy, changes in sleep patterns such as insomnia or sleeping too much, changes in appetite, chronic aches and pains, difficulty concentrating, social withdrawal, irritability, and lack of interest in activities that were previously enjoyable. If someone is experiencing several of these signs, it could indicate depression and they should seek treatment from a mental health professional.