Depression affects millions of people each year across all ages and demographics. Some of the top 10 signs of depression include persistent feelings of sadness, lack of energy, changes in sleep patterns such as insomnia or sleeping too much, changes in appetite, chronic aches and pains, difficulty concentrating, social withdrawal, irritability, and lack of interest in activities that were previously enjoyable. If someone is experiencing several of these signs, it could indicate depression and they should seek treatment from a mental health professional.
Depression manifests in many ways beyond common symptoms like crying and low energy. This document outlines 5 less common signs of depression: rapid weight changes from loss of appetite or binging; short temper and irritability; increased boredom where activities are no longer enjoyable; unexplained aches and pains when no medical cause is found; and trouble making simple decisions due to feeling overwhelmed. Recognizing these less obvious signs can help identify depression in oneself or a loved one.
6 signs you’re unhealthy that you probably shouldn’t ignorekirti betai
The document outlines 6 common signs that your body gives to indicate you may be unhealthy:
1. The color of your urine can indicate dehydration or issues with vital organs like your kidneys.
2. Irregular bowel movements and difficulty having daily bowel movements can mean your body is not properly removing toxins.
3. Frequent chapped lips can be a sign of dehydration rather than just dry conditions.
4. Chronic fatigue even after adequate sleep could mean issues with your diet, thyroid, or other health problems.
5. Recurrent skin breakouts could reflect an impaired immune system aggravated by stress.
6. Easily catching seasonal illnesses like colds or flu each year may indicate
Chronic Fatigue Syndrome (CFS) is a condition characterized by severe chronic fatigue lasting over six months along with symptoms like sore throat, muscle pain, and impaired memory or concentration. The cause is unknown but CFS is often accompanied by depression. Exercise can help CFS patients feel more energized if started moderately to avoid increased fatigue, and yoga has proven benefits for relieving pain and fatigue as well as improving psychological well-being. Risks of exercise for CFS patients include feeling more fatigued, so a personal trainer would need to modify workouts appropriately.
Chronic Fatigue Syndrome (CFS) is a condition characterized by severe chronic fatigue lasting over six months along with symptoms like sore throat, muscle pain, and impaired memory or concentration. The cause is unknown but CFS is often accompanied by depression. Exercise can help CFS patients feel more energized if started moderately to avoid increased fatigue, and yoga has benefits for both physical and mental recovery. Risks of exercise include feeling more fatigued, so a personal trainer would need to modify workouts for any CFS clients.
The document discusses the health benefits of exercise. It states that exercise can boost energy, improve mood, manage weight, increase self-confidence, promote better sleep, and decrease the risk of chronic conditions like type 2 diabetes. Regular physical activity delivers nutrients to tissues, makes the cardiovascular system more efficient, and makes muscles more sensitive to insulin, helping to prevent diabetes and its complications. The conclusion emphasizes that exercise is good for both physical and mental health.
This document discusses signs and symptoms of stress and methods for managing stress. It begins by outlining major physical signs of stress like aches, pains, headaches and digestive issues that can result from long-term chronic stress. It then notes mental and emotional signs like insomnia, excessive sleeping, and difficulties with responsibilities and decision making. Finally, it recommends several methods for managing stress, including exercise, eating well, spending time with friends, getting enough sleep, avoiding substances like alcohol, and making time each day to relax and reflect.
Depression affects millions of people each year across all ages and demographics. Some of the top 10 signs of depression include persistent feelings of sadness, lack of energy, changes in sleep patterns such as insomnia or sleeping too much, changes in appetite, chronic aches and pains, difficulty concentrating, social withdrawal, irritability, and lack of interest in activities that were previously enjoyable. If someone is experiencing several of these signs, it could indicate depression and they should seek treatment from a mental health professional.
Depression manifests in many ways beyond common symptoms like crying and low energy. This document outlines 5 less common signs of depression: rapid weight changes from loss of appetite or binging; short temper and irritability; increased boredom where activities are no longer enjoyable; unexplained aches and pains when no medical cause is found; and trouble making simple decisions due to feeling overwhelmed. Recognizing these less obvious signs can help identify depression in oneself or a loved one.
6 signs you’re unhealthy that you probably shouldn’t ignorekirti betai
The document outlines 6 common signs that your body gives to indicate you may be unhealthy:
1. The color of your urine can indicate dehydration or issues with vital organs like your kidneys.
2. Irregular bowel movements and difficulty having daily bowel movements can mean your body is not properly removing toxins.
3. Frequent chapped lips can be a sign of dehydration rather than just dry conditions.
4. Chronic fatigue even after adequate sleep could mean issues with your diet, thyroid, or other health problems.
5. Recurrent skin breakouts could reflect an impaired immune system aggravated by stress.
6. Easily catching seasonal illnesses like colds or flu each year may indicate
Chronic Fatigue Syndrome (CFS) is a condition characterized by severe chronic fatigue lasting over six months along with symptoms like sore throat, muscle pain, and impaired memory or concentration. The cause is unknown but CFS is often accompanied by depression. Exercise can help CFS patients feel more energized if started moderately to avoid increased fatigue, and yoga has proven benefits for relieving pain and fatigue as well as improving psychological well-being. Risks of exercise for CFS patients include feeling more fatigued, so a personal trainer would need to modify workouts appropriately.
Chronic Fatigue Syndrome (CFS) is a condition characterized by severe chronic fatigue lasting over six months along with symptoms like sore throat, muscle pain, and impaired memory or concentration. The cause is unknown but CFS is often accompanied by depression. Exercise can help CFS patients feel more energized if started moderately to avoid increased fatigue, and yoga has benefits for both physical and mental recovery. Risks of exercise include feeling more fatigued, so a personal trainer would need to modify workouts for any CFS clients.
The document discusses the health benefits of exercise. It states that exercise can boost energy, improve mood, manage weight, increase self-confidence, promote better sleep, and decrease the risk of chronic conditions like type 2 diabetes. Regular physical activity delivers nutrients to tissues, makes the cardiovascular system more efficient, and makes muscles more sensitive to insulin, helping to prevent diabetes and its complications. The conclusion emphasizes that exercise is good for both physical and mental health.
This document discusses signs and symptoms of stress and methods for managing stress. It begins by outlining major physical signs of stress like aches, pains, headaches and digestive issues that can result from long-term chronic stress. It then notes mental and emotional signs like insomnia, excessive sleeping, and difficulties with responsibilities and decision making. Finally, it recommends several methods for managing stress, including exercise, eating well, spending time with friends, getting enough sleep, avoiding substances like alcohol, and making time each day to relax and reflect.
Stress comes in many forms and can affect people differently. It is caused by stressors like work, relationships, life changes, the environment, and self-generated pressures. Acute stress occurs due to recent pressures while chronic stress is long-term and grinds people down over time. While small amounts of stress can boost performance, too much stress takes a negative toll by weakening the immune system and potentially leading to health issues like heart disease, fatigue, and depression. Managing stress is important for students to maintain a healthy lifestyle and avoid its dangers.
This document discusses how stress and depression affect the immune system. It defines stress and depression, describes their symptoms and common treatment options. Stress and depression can weaken the immune system by impacting cardiovascular health and making it harder to maintain a healthy lifestyle. Over the long-term, an impaired immune system due to prolonged stress or depression can damage the body. The document emphasizes the importance of recognizing signs of stress or depression and seeking help through lifestyle changes or medical treatment.
Forty Ways to Kill Stress Before it Kills YouRay Gebauer
This document summarizes and promotes the book "How to Cure and Prevent Any Disease" by Ray Gebauer. It includes endorsements from several doctors praising the book. The document then discusses stress, describing it as both good and harmful depending on the situation. Too much unresolved stress without recovery time is presented as the single cause of all health problems. Various stress-reducing techniques are proposed to help manage stress levels.
This document discusses anxiety disorders, their causes, symptoms, and treatments. It defines anxiety as a normal part of life but distinguishes anxiety disorders as different from everyday worries. It lists several common anxiety disorders including generalized anxiety disorder, obsessive compulsive disorder, panic disorder, post-traumatic stress disorder, and social anxiety disorder. It discusses brain chemistry, life experiences, genetics, and learned behaviors/thinking patterns as potential causes. It provides details on symptoms for each disorder and explains how anxiety manifests physically through breathing issues, tight muscles, rapid heart rate, sweating/cold extremities, stomach issues, and muscle pain/stiffness. It recommends identifying triggers, cognitive behavioral therapy, meditation, supplements/diet changes, exercise
Magnesium Breakthrough is an all-natural dietary supplement from BioOptimizers designed to improve your nervous system and stress levels. Magnesium Breakthrough is an incredible value, considering it’s one of the most transformative supplements any human being can take. May support digestion and promote a more restful sleep.
Forty Ways to Kill Stress Before it Kills YouRay Gebauer
This document summarizes a book about stress and its effects on health. It discusses that stress itself is not inherently harmful, but excessive unresolved stress over time, known as "stress overload", can accelerate aging and lead to disease. It identifies five main sources of stress: physical, chemical, electromagnetic, deficiency-based, and psychological stress. The document advocates reducing stress through various techniques in order to build health and prevent disease.
Stress isn’t always bad.
In small doses, it can help you perform under pressure and motivate you to do your best. But when you’re constantly running in emergency mode, your mind and body pay the price.
If you frequently find yourself feeling frazzled and overwhelmed, it’s time to take action to bring your nervous system back into balance.
You can protect yourself and improve how you think and feel by learning how to recognize the signs and symptoms of chronic stress and taking steps to reduce its harmful effects.
Stress is your body’s way of responding to any kind of demand or threat.
Eustress – Kind of stress that results from something good and we react positive.
Distress – Kind of stress that results from something bad and we react negative.
Stressors are things that cause stress. Almost everything is a stressor depending on the individual.
Past Present and Future "Tense" - Feeling Tensed? You're not AloneDeepak Menon
This presentation is aimed as an awareness for students on how they can cope with tension and stress. The presentation also gives few steps that can be taken to minimize the effects of these on students and in general.
Modern life has become a strain on millions of Americans. It seems that stress is everywhere we go whether it be work, school, on the road and even at home. For many people it seems nearly impossible to get away from the stress. It seems to be everywhere we turn. Stress can also be a motivator and an encourager for change. Stress is a part of life, this means that we must manage our stress rather than run from it.
The document discusses stress management and burnout prevention. It begins by describing how stress can slowly boil like a frog in water until a person reaches exhaustion and burnout. It then provides definitions of stress, stress management, and burnout. The document outlines 14 facts about stress and its health impacts and provides 7 tips for managing stress, such as understanding stress triggers and prioritizing self-care. It aims to equip readers with tools to better manage stress and find a healthier work-life balance.
This document summarizes effective stress management techniques. It discusses that stress is perceived differently by each individual based on their inner perspective. Changing one's perspective can help manage stress. It also suggests relaxing techniques like deep breathing to reduce stress levels. Overall it emphasizes the importance of perspective in stress management and provides visual examples to demonstrate how stress can alter one's perceptions.
Depression is a serious medical illness that involves changes in the brain and can cause constant feelings of sadness, irritability, loss of energy, changes in appetite and sleep, feelings of worthlessness, difficulty concentrating, and thoughts of death or suicide. It affects about 16% of Americans at some point in their lives and is more common in women. While it can be caused by factors like family history, trauma, stress or other psychological disorders, seeking treatment through psychotherapy or medication can help manage symptoms and improve mood.
Forty Ways to Kill Stress Before it Kills YouRay Gebauer
This document summarizes and promotes the book "How to Cure and Prevent Any Disease" by Ray Gebauer. It contains endorsements from medical doctors praising the book. It then discusses the key concepts in the book around stress being the single cause of disease. It identifies five sources of stress: physical, chemical, electromagnetic, deficiency-based, and psychological. It provides examples of each type of stress and argues that excess stress overload leads to health problems.
Anxiety is a major problem in society that stems from life becoming too complex and demanding. Physical symptoms of anxiety include increased heart rate, sweating, and shortness of breath as the body prepares for a perceived threat. Panic attacks are also common and cause feelings of impending doom. While anxiety affects people differently, it is often related to individual circumstances and can lead to depression if left untreated. Developing endorphins through meditation can help reduce anxiety by cultivating a calm mind and letting go of unhealthy mental states, though professional help is also usually needed.
The document discusses managing stress during the COVID-19 lockdown period. It defines stress and its types such as acute stress, episodic acute stress, and chronic stress. It lists physical, emotional, and mental symptoms of stress. It explains how stress arises due to external factors like fear of the pandemic and internal factors like negative emotions. It discusses how hormones like cortisol and adrenaline are released in the body during stress and their negative health impacts if levels remain high for long periods. Finally, it provides several ways to manage stress like getting sufficient sleep, exercising, spending time with family, practicing relaxation techniques, and maintaining a healthy lifestyle.
Depression is more than simply feeling sad, guilty, or a feeling of blue once in a while. Being depressed can make you feel vulnerable. But you're definitely not. Depression can have an impact on one's day to day activities, emotions, thoughts and one's health. It can have an impact on one's family life, social life and work life. That said, depression is also not an indication of weakness or a deficiency. Just like any physical health problem, depression is treatable with a high rate of success. Antidepressants are one of the ways to deal with treating symptoms of significant depressions and myths regarding the same needs to be addressed.
The document provides information about stress, sources of stress for teens, and effective stress management techniques. It defines stress as mental or emotional tension resulting from demanding circumstances. Common sources of stress for teens include school demands, peer and family problems, and physical changes during puberty. The document recommends several stress management techniques for teens such as exercise, relaxation exercises, assertiveness training, and spending time with supportive friends. It also provides examples of effective stress management tools like reframing negative thoughts and lists emergency stress stoppers and stress-busting activities.
The document discusses several topics related to mental health including causes, symptoms, and treatment. It defines mental health as maintaining successful mental activity including daily activities and relationships. Mental illness is described as abnormal brain functioning that can be caused by both genetics and environment interacting, rather than just stress. Common mental health challenges are mentioned such as depression, anxiety, and schizophrenia. The document emphasizes that mental illness is treatable and those with mental illness can live productive lives with treatment. It encourages seeking help from others if experiencing feelings of sadness, stress, or worry.
Depression is a common and serious medical illness that negatively impacts mood, thinking, and behavior. It causes feelings of sadness and loss of interest in activities. Depression episodes last at least two weeks and can be ongoing or chronic in nature. Conditions like arthritis, asthma, cardiovascular disease, cancer, diabetes and obesity can worsen due to depression. Signs of depression include feelings of sadness, emptiness, hopelessness, crying, loss of interest in hobbies, fatigue, difficulty concentrating, changes in appetite or sleep, and thoughts of death or self-harm. Depression is caused by changes in brain chemistry, hormones, family history, early childhood trauma, brain structure, medical conditions, substance use, and chronic pain. Teachers can
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Stress comes in many forms and can affect people differently. It is caused by stressors like work, relationships, life changes, the environment, and self-generated pressures. Acute stress occurs due to recent pressures while chronic stress is long-term and grinds people down over time. While small amounts of stress can boost performance, too much stress takes a negative toll by weakening the immune system and potentially leading to health issues like heart disease, fatigue, and depression. Managing stress is important for students to maintain a healthy lifestyle and avoid its dangers.
This document discusses how stress and depression affect the immune system. It defines stress and depression, describes their symptoms and common treatment options. Stress and depression can weaken the immune system by impacting cardiovascular health and making it harder to maintain a healthy lifestyle. Over the long-term, an impaired immune system due to prolonged stress or depression can damage the body. The document emphasizes the importance of recognizing signs of stress or depression and seeking help through lifestyle changes or medical treatment.
Forty Ways to Kill Stress Before it Kills YouRay Gebauer
This document summarizes and promotes the book "How to Cure and Prevent Any Disease" by Ray Gebauer. It includes endorsements from several doctors praising the book. The document then discusses stress, describing it as both good and harmful depending on the situation. Too much unresolved stress without recovery time is presented as the single cause of all health problems. Various stress-reducing techniques are proposed to help manage stress levels.
This document discusses anxiety disorders, their causes, symptoms, and treatments. It defines anxiety as a normal part of life but distinguishes anxiety disorders as different from everyday worries. It lists several common anxiety disorders including generalized anxiety disorder, obsessive compulsive disorder, panic disorder, post-traumatic stress disorder, and social anxiety disorder. It discusses brain chemistry, life experiences, genetics, and learned behaviors/thinking patterns as potential causes. It provides details on symptoms for each disorder and explains how anxiety manifests physically through breathing issues, tight muscles, rapid heart rate, sweating/cold extremities, stomach issues, and muscle pain/stiffness. It recommends identifying triggers, cognitive behavioral therapy, meditation, supplements/diet changes, exercise
Magnesium Breakthrough is an all-natural dietary supplement from BioOptimizers designed to improve your nervous system and stress levels. Magnesium Breakthrough is an incredible value, considering it’s one of the most transformative supplements any human being can take. May support digestion and promote a more restful sleep.
Forty Ways to Kill Stress Before it Kills YouRay Gebauer
This document summarizes a book about stress and its effects on health. It discusses that stress itself is not inherently harmful, but excessive unresolved stress over time, known as "stress overload", can accelerate aging and lead to disease. It identifies five main sources of stress: physical, chemical, electromagnetic, deficiency-based, and psychological stress. The document advocates reducing stress through various techniques in order to build health and prevent disease.
Stress isn’t always bad.
In small doses, it can help you perform under pressure and motivate you to do your best. But when you’re constantly running in emergency mode, your mind and body pay the price.
If you frequently find yourself feeling frazzled and overwhelmed, it’s time to take action to bring your nervous system back into balance.
You can protect yourself and improve how you think and feel by learning how to recognize the signs and symptoms of chronic stress and taking steps to reduce its harmful effects.
Stress is your body’s way of responding to any kind of demand or threat.
Eustress – Kind of stress that results from something good and we react positive.
Distress – Kind of stress that results from something bad and we react negative.
Stressors are things that cause stress. Almost everything is a stressor depending on the individual.
Past Present and Future "Tense" - Feeling Tensed? You're not AloneDeepak Menon
This presentation is aimed as an awareness for students on how they can cope with tension and stress. The presentation also gives few steps that can be taken to minimize the effects of these on students and in general.
Modern life has become a strain on millions of Americans. It seems that stress is everywhere we go whether it be work, school, on the road and even at home. For many people it seems nearly impossible to get away from the stress. It seems to be everywhere we turn. Stress can also be a motivator and an encourager for change. Stress is a part of life, this means that we must manage our stress rather than run from it.
The document discusses stress management and burnout prevention. It begins by describing how stress can slowly boil like a frog in water until a person reaches exhaustion and burnout. It then provides definitions of stress, stress management, and burnout. The document outlines 14 facts about stress and its health impacts and provides 7 tips for managing stress, such as understanding stress triggers and prioritizing self-care. It aims to equip readers with tools to better manage stress and find a healthier work-life balance.
This document summarizes effective stress management techniques. It discusses that stress is perceived differently by each individual based on their inner perspective. Changing one's perspective can help manage stress. It also suggests relaxing techniques like deep breathing to reduce stress levels. Overall it emphasizes the importance of perspective in stress management and provides visual examples to demonstrate how stress can alter one's perceptions.
Depression is a serious medical illness that involves changes in the brain and can cause constant feelings of sadness, irritability, loss of energy, changes in appetite and sleep, feelings of worthlessness, difficulty concentrating, and thoughts of death or suicide. It affects about 16% of Americans at some point in their lives and is more common in women. While it can be caused by factors like family history, trauma, stress or other psychological disorders, seeking treatment through psychotherapy or medication can help manage symptoms and improve mood.
Forty Ways to Kill Stress Before it Kills YouRay Gebauer
This document summarizes and promotes the book "How to Cure and Prevent Any Disease" by Ray Gebauer. It contains endorsements from medical doctors praising the book. It then discusses the key concepts in the book around stress being the single cause of disease. It identifies five sources of stress: physical, chemical, electromagnetic, deficiency-based, and psychological. It provides examples of each type of stress and argues that excess stress overload leads to health problems.
Anxiety is a major problem in society that stems from life becoming too complex and demanding. Physical symptoms of anxiety include increased heart rate, sweating, and shortness of breath as the body prepares for a perceived threat. Panic attacks are also common and cause feelings of impending doom. While anxiety affects people differently, it is often related to individual circumstances and can lead to depression if left untreated. Developing endorphins through meditation can help reduce anxiety by cultivating a calm mind and letting go of unhealthy mental states, though professional help is also usually needed.
The document discusses managing stress during the COVID-19 lockdown period. It defines stress and its types such as acute stress, episodic acute stress, and chronic stress. It lists physical, emotional, and mental symptoms of stress. It explains how stress arises due to external factors like fear of the pandemic and internal factors like negative emotions. It discusses how hormones like cortisol and adrenaline are released in the body during stress and their negative health impacts if levels remain high for long periods. Finally, it provides several ways to manage stress like getting sufficient sleep, exercising, spending time with family, practicing relaxation techniques, and maintaining a healthy lifestyle.
Depression is more than simply feeling sad, guilty, or a feeling of blue once in a while. Being depressed can make you feel vulnerable. But you're definitely not. Depression can have an impact on one's day to day activities, emotions, thoughts and one's health. It can have an impact on one's family life, social life and work life. That said, depression is also not an indication of weakness or a deficiency. Just like any physical health problem, depression is treatable with a high rate of success. Antidepressants are one of the ways to deal with treating symptoms of significant depressions and myths regarding the same needs to be addressed.
The document provides information about stress, sources of stress for teens, and effective stress management techniques. It defines stress as mental or emotional tension resulting from demanding circumstances. Common sources of stress for teens include school demands, peer and family problems, and physical changes during puberty. The document recommends several stress management techniques for teens such as exercise, relaxation exercises, assertiveness training, and spending time with supportive friends. It also provides examples of effective stress management tools like reframing negative thoughts and lists emergency stress stoppers and stress-busting activities.
The document discusses several topics related to mental health including causes, symptoms, and treatment. It defines mental health as maintaining successful mental activity including daily activities and relationships. Mental illness is described as abnormal brain functioning that can be caused by both genetics and environment interacting, rather than just stress. Common mental health challenges are mentioned such as depression, anxiety, and schizophrenia. The document emphasizes that mental illness is treatable and those with mental illness can live productive lives with treatment. It encourages seeking help from others if experiencing feelings of sadness, stress, or worry.
Depression is a common and serious medical illness that negatively impacts mood, thinking, and behavior. It causes feelings of sadness and loss of interest in activities. Depression episodes last at least two weeks and can be ongoing or chronic in nature. Conditions like arthritis, asthma, cardiovascular disease, cancer, diabetes and obesity can worsen due to depression. Signs of depression include feelings of sadness, emptiness, hopelessness, crying, loss of interest in hobbies, fatigue, difficulty concentrating, changes in appetite or sleep, and thoughts of death or self-harm. Depression is caused by changes in brain chemistry, hormones, family history, early childhood trauma, brain structure, medical conditions, substance use, and chronic pain. Teachers can
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
4. How much stress is too much?
Because of the widespread damage stress can cause, it’s
important to know your own limit. But just how much stress
is “too much” differs from person to person. Some people
seem to be able to roll with life’s punches, while others tend
to crumble in the face of small obstacles or frustrations.
Some people even thrive on the excitement of a high-stress
lifestyle.
5.
6. Here's a 2017 award winning short film
"This Is What Depression Feels Like"
explore what is depression mean to a adult person!