Tissue regeneration is an emerging and exciting biomedical field. As a scientist, choose either an adult stem cell population or embryonic stem cells as a model system to develop a technique for growing artificial limbs in culture. Be sure to explain why you chose your particular stem cell and the drawbacks associated with the one that you did not choose for your experiments. Solution In tissue regeneration scientists choose only embryonic stem cells as a models system to develop a technique for growing artificial limbs in culture. In case of salamanders have unusual and very desirable characteristics of being able replicate limb. When salamanders loses a limb does not form scab. Instead a wound epidermis forms it known as apical epithelial cells they form blastema. This knob of stem cells is then able completely regenerate the limb, these blastemata like MRL mice act as embryonic stem cells. Embryonic stem cells: 1. It is pluripotent i.e., differentiate into 3 of the primary germ layers (ectoderm, endoderm, mesoderm) this indicates that embryonic stem cells can potentially differentiate into adult human cell if stimulated right way Drawbacks of adult stem cells: 1.It is multipotent meaning that each can only produced limited cell type. 2. Unlike embryonic stem cells, they are much scarcer and harder to culture so its not choosen by scientist to develop for growing artificial limbs in culture..

1. Tissue regeneration is an emerging and exciting biomedical field. As a scientist, choose either an
adult stem cell population or embryonic stem cells as a model system to develop a technique for
growing artificial limbs in culture. Be sure to explain why you chose your particular stem cell
and the drawbacks associated with the one that you did not choose for your experiments.
Solution
In tissue regeneration scientists choose only embryonic stem cells as a models system to develop
a technique for growing artificial limbs in culture. In case of salamanders have unusual and very
desirable characteristics of being able replicate limb. When salamanders loses a limb does not
form scab. Instead a wound epidermis forms it known as apical epithelial cells they form
blastema. This knob of stem cells is then able completely regenerate the limb, these blastemata
like MRL mice act as embryonic stem cells.
Embryonic stem cells:
1. It is pluripotent i.e., differentiate into 3 of the primary germ layers (ectoderm, endoderm,
mesoderm) this indicates that embryonic stem cells can potentially differentiate into adult human
cell if stimulated right way
Drawbacks of adult stem cells:
1.It is multipotent meaning that each can only produced limited cell type.
2. Unlike embryonic stem cells, they are much scarcer and harder to culture
so its not choosen by scientist to develop for growing artificial limbs in culture.