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Epimorphic
regeneration
    By: Mafer Manrique
From researches people have found a way of
regenerating fingers, I read this article about the
topic:
http://science.howstuffworks.com/environmental/life/human
-biology/extracellular-matrix.htm
This article is about a man who lost a
fingertip with a airplane model, and his
brother gave him a powder that helped to
regrow fingers. After some months the
finger was exactly the same as it was
before he flew it off.
After I read this I got very interested in the
topic and I wanted to research more about
it.
is the restoration of lost tissues and structures
  from a cell known as a blastema.




Epimorphic Regeneration
 Blastema is a mass of cells capable
 of growing and regenerating into
 organs or body parts.




Blastema
 Historically
             blastema have been
 thought to be made of
 undifferentiated pluripotent cells, but
 recent research show that in some
 organisms blastema may retain
 memory of tissue origin.



Blastema
   Blastemata is typically found in the early
    stages of an organism's development such
    as in embryos, and in the regeneration of
    tissues, organs and bones.




Blastema
 The epidermal cells from the edges
 of the wound migrate and spread
 over the exposed surface. This is
 known as wound healing.




Description
A few days later, undifferentiated
 cells accumulate inside the
 epidermis, becoming a bulge. This is
 known as regeneration bud or
 blastema.




Blastema formation
 Theblastema develops the missing
 parts of the lost organ, like the digits
 which grow into new digits.




Description
 Theregenerated limb grows until it
 reaches the size of a normal limb.




Growth
Step by step Animated
                         regeneration

Lizard limb Epimorphic
regeneration




Examples
After several researches scientists have
 found a way humans can regenerate
 fingers.

   Human fetuses can regenerate almost all
    body parts wile they are in the womb. As
    soon as they are born they lost that
    ability.


Epimorphic regenerations in
Humans
   According to regeneration researcher Dr.
    Stephen Badylak of the University of
    Pittsburgh, children up to the age of two
    have been known to regrow fingertips
    with no outside help.
   The extract, called extracellular matrix,
    lays the framework that cells use to
    generate any given body part.
   It holds the signals that tell cells to divide,
    differentiate and build themselves into a
    specific form. This extract can be use by
    humans to regrow fingertips.
   Let's take the case of a person who loses
    the tip of a finger. When the finger is cut
    off, the cells die, and their contents seep
    into the surrounding tissue.




Examples
   This alerts the immune system to a
    problem. The immune system's response
    to cell death is inflammation and scar
    tissue. The formation of scar tissue
    prevents any future cellular development
    in the area.
   When scars appear the cells can’t work,
    and can’t repair the damage in top of that
    skin.

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Epimorphic regeneration science project

  • 1. Epimorphic regeneration By: Mafer Manrique
  • 2. From researches people have found a way of regenerating fingers, I read this article about the topic: http://science.howstuffworks.com/environmental/life/human -biology/extracellular-matrix.htm This article is about a man who lost a fingertip with a airplane model, and his brother gave him a powder that helped to regrow fingers. After some months the finger was exactly the same as it was before he flew it off. After I read this I got very interested in the topic and I wanted to research more about it.
  • 3. is the restoration of lost tissues and structures from a cell known as a blastema. Epimorphic Regeneration
  • 4.  Blastema is a mass of cells capable of growing and regenerating into organs or body parts. Blastema
  • 5.  Historically blastema have been thought to be made of undifferentiated pluripotent cells, but recent research show that in some organisms blastema may retain memory of tissue origin. Blastema
  • 6. Blastemata is typically found in the early stages of an organism's development such as in embryos, and in the regeneration of tissues, organs and bones. Blastema
  • 7.  The epidermal cells from the edges of the wound migrate and spread over the exposed surface. This is known as wound healing. Description
  • 8. A few days later, undifferentiated cells accumulate inside the epidermis, becoming a bulge. This is known as regeneration bud or blastema. Blastema formation
  • 9.  Theblastema develops the missing parts of the lost organ, like the digits which grow into new digits. Description
  • 10.  Theregenerated limb grows until it reaches the size of a normal limb. Growth
  • 11. Step by step Animated regeneration Lizard limb Epimorphic regeneration Examples
  • 12. After several researches scientists have found a way humans can regenerate fingers.  Human fetuses can regenerate almost all body parts wile they are in the womb. As soon as they are born they lost that ability. Epimorphic regenerations in Humans
  • 13. According to regeneration researcher Dr. Stephen Badylak of the University of Pittsburgh, children up to the age of two have been known to regrow fingertips with no outside help.
  • 14. The extract, called extracellular matrix, lays the framework that cells use to generate any given body part.
  • 15. It holds the signals that tell cells to divide, differentiate and build themselves into a specific form. This extract can be use by humans to regrow fingertips.
  • 16. Let's take the case of a person who loses the tip of a finger. When the finger is cut off, the cells die, and their contents seep into the surrounding tissue. Examples
  • 17. This alerts the immune system to a problem. The immune system's response to cell death is inflammation and scar tissue. The formation of scar tissue prevents any future cellular development in the area.
  • 18. When scars appear the cells can’t work, and can’t repair the damage in top of that skin.