This document provides a summary of key events from 1787 to 1861 that led to the outbreak of the American Civil War, including the adoption of the 3/5 compromise and the Fugitive Slave Act in the Constitution, the Missouri Compromise of 1820, the Kansas-Nebraska Act of 1854, the Dred Scott decision of 1857, John Brown's raid in 1859, secession by Southern states after Lincoln's election in 1860, and the firing on Fort Sumter in April 1861 that marked the beginning of the war. These events show the increasing tensions around the issue of slavery and states' rights that could not be resolved through political compromises.