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The Future of IPRs &
Bio-Pharmaceutical Innovation from
The Global South
Chirantan Chatterjee
IIMA & Hoover Institution, Stanford University
www.chirantanchatterjee.com
Changing Nature of Innovation Conference
Ahmedabad University and CTIER
May 2021
Of a previous pathogenic outbreak discovery in 2010
India a hotbed of AMR, yet Carbapenem sales go up!
Why Is it that We are Not generating New Antibiotics?
Some Answers from a Field Trip in Summer 2007-2008
- Agglomeration Economies.
- Where is the Scientist-Entrepreneur? (Bayh
Dole Act & Pasteur’s Quadrant).
- Even pre-Covid no Patient Venture Capital.
- Human Capital Issues.
- An extinct taste for biology while focusing on
chemistry in the last 5 decades.
- Regulatory flipflops & flight of entrepreneurs
to locations like Singapore.
- Other locations rising (S-Korea, Bangladesh
among others).
- India and perhaps global south, more and more
an incrementally innovative society (than a
radically innovative society).
- Services & tech innovation takes precedence
over a life-science economy.
Where to Next for the Industry?
- Biosimilars (requires science, clinical trials,
regulation)
- Preventive Innovation than Therapeutic
Innovation (Medical Devices startups like
Janacare, Xcyton Diagnostics, Achira et al.)
- Drug Repurposing (Beyond Lopinavir).
- R&D versus non R&D Alliances (the Roche-Cipla
efforts).
- Structural Shifts in Innovation Ecosystem
Required
- Taking advantage of the mRNA Disruption as
other countries catch up.
- Forming R&D Consortiums ala the Japanese?
- Differding, E. (2017). The Drug Discovery and
Development Industry in India—Two Decades of
Proprietary Small‐Molecule R&D.
ChemMedChem, 12(11), 786-818.
Global R&D Situation 2021 - India appears, more expected
Global R&D Situation 2021 - The Molnupiravir Effect
Global R&D Situation 2021 - Oncology Dominates
Global R&D Situation 2021 - Changing Nature of Innovation
Global R&D Situation 2021
Role of Global South/India in Flourishing Markets for Technology?
Global R&D Situation 2021
Role of Global South/India in Flourishing Markets for Technology?
Push & Pull Regulatory Shifts - Local & Global
Covid-19 Patent Waiver, RCEP, LDC TRIPS transition, Geo-Politics et al.
Thank You - Health & Wealth - Tough New World & Trade-offs Ahead..
■ “There is nothing I fear more than
waking up without a program that will
help me bring a little happiness to
those with no resources, those who are
poor, illiterate, and ridden with
terminal disease.” - Nelson Mandela.

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The Future of IPRs & Bio-Pharmaceutical Innovation from The Global South

  • 1. The Future of IPRs & Bio-Pharmaceutical Innovation from The Global South Chirantan Chatterjee IIMA & Hoover Institution, Stanford University www.chirantanchatterjee.com Changing Nature of Innovation Conference Ahmedabad University and CTIER May 2021
  • 2. Of a previous pathogenic outbreak discovery in 2010
  • 3. India a hotbed of AMR, yet Carbapenem sales go up!
  • 4. Why Is it that We are Not generating New Antibiotics?
  • 5. Some Answers from a Field Trip in Summer 2007-2008 - Agglomeration Economies. - Where is the Scientist-Entrepreneur? (Bayh Dole Act & Pasteur’s Quadrant). - Even pre-Covid no Patient Venture Capital. - Human Capital Issues. - An extinct taste for biology while focusing on chemistry in the last 5 decades. - Regulatory flipflops & flight of entrepreneurs to locations like Singapore. - Other locations rising (S-Korea, Bangladesh among others). - India and perhaps global south, more and more an incrementally innovative society (than a radically innovative society). - Services & tech innovation takes precedence over a life-science economy.
  • 6. Where to Next for the Industry? - Biosimilars (requires science, clinical trials, regulation) - Preventive Innovation than Therapeutic Innovation (Medical Devices startups like Janacare, Xcyton Diagnostics, Achira et al.) - Drug Repurposing (Beyond Lopinavir). - R&D versus non R&D Alliances (the Roche-Cipla efforts). - Structural Shifts in Innovation Ecosystem Required - Taking advantage of the mRNA Disruption as other countries catch up. - Forming R&D Consortiums ala the Japanese? - Differding, E. (2017). The Drug Discovery and Development Industry in India—Two Decades of Proprietary Small‐Molecule R&D. ChemMedChem, 12(11), 786-818.
  • 7. Global R&D Situation 2021 - India appears, more expected
  • 8. Global R&D Situation 2021 - The Molnupiravir Effect
  • 9. Global R&D Situation 2021 - Oncology Dominates
  • 10. Global R&D Situation 2021 - Changing Nature of Innovation
  • 11. Global R&D Situation 2021 Role of Global South/India in Flourishing Markets for Technology?
  • 12. Global R&D Situation 2021 Role of Global South/India in Flourishing Markets for Technology?
  • 13. Push & Pull Regulatory Shifts - Local & Global
  • 14. Covid-19 Patent Waiver, RCEP, LDC TRIPS transition, Geo-Politics et al.
  • 15. Thank You - Health & Wealth - Tough New World & Trade-offs Ahead.. ■ “There is nothing I fear more than waking up without a program that will help me bring a little happiness to those with no resources, those who are poor, illiterate, and ridden with terminal disease.” - Nelson Mandela.