The document discusses the rise of digital physician key opinion leaders (KOLs) as a new paradigm in healthcare. Digital KOLs are physician experts who are also leaders in social media and champions of patient engagement and digital tools. They serve as advisors to digital health companies, help design medical apps and mobile clinical trials, and disseminate health information via social media to both professionals and patients. The digital age requires a new approach from the pharmaceutical industry, and digital physician KOLs can help drive this transition by promoting digital interactions and partnerships.