Pharmaceutical technology .pptx
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This document discusses pulmonary drug delivery systems. It describes the anatomy of the respiratory tract, including the conducting system and respiratory region. It also discusses factors that affect particle deposition in the lungs, including physiological factors like lung morphology, breathing patterns, and tidal volume as well as pharmaceutical factors like particle shape, density and size. The document also briefly outlines the mechanisms of drug absorption in the lungs, including diffusion, absorption, and phagocytosis. Finally, it lists some generic drug names used to treat respiratory diseases.
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ุตุญู ุฃุญุฑู ุงูุฎูุงู ูููุฑุงุก ุงูุนุดุฑุฉุฃุนุฏ ุฃุญุฑู ุงูุฎูุงู ุจุงูุชูููู ูุตูุง ุณู
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- 1. Pulmonary Drug Delivery System Kamal Uddin Rayhan Present by North South University Batch 151 Part-01
- 2. Pulmonary Drug Delivery Delivery drug to the respiratory system is performed for diagnostic and treatment of local disorder. Upper airways -nasal cavity, pharynx and larynx Lower airways -trachea, primary bronchi and bronchial tree. Its readily absorption site and gain systemic absorption. Old therapy that have first pass metabolism.
- 3. Anatomy of Respiratory Tract Two region respiratory tract- โข The conducting system โข Respiratory region The lungs are divided into lobes; The left lung is composed of the upper lobe, the lower lobe and the lingual (a small remnant next to the apex of the heart), the right lung is composed of the upper, the middle and the lower lobes
- 4. Anatomy of Respiratory Tract
- 6. Cell of Lung region
- 7. Factors effecting particle deposition in air There are two factors- 1.Physiological Factors. 2.Pharmaceutical Factors. ๏ฑ Lung morphology. ๏ฑ Oral vs Nasal breathing. ๏ฑ Inspiratory flow rate(IFR) ๏ฑ Co-ordination of aerosol generation with inspiration. ๏ฑ Tidal Volume. ๏ฑ Breath Holding. 01) Physiological Factor-
- 8. ๏ฑ Shape. ๏ฑ Density. ๏ฑ Size of particles. ๏ฑ Physical Stability. 02) Pharmaceutical Factors- Factors effecting particle deposition in air Mechanism of Drug Absorption o Diffusion o Absorption o Phagocytosis
- 9. Mechanism of Pulmonary Drug absorption-
- 10. Generic Names of Drugs for Treatment of Respiratory Diseases 1. Ambroxol 2. Aminophyllin 3. Amoxicillin 4. Calfactant etc