This document outlines a teaching manual for an 8th standard biology lesson on diseases that reduce agricultural yield. The lesson aims to develop students' knowledge, process skills, and attitudes on this topic through various teaching methods. Key points covered include common plant and animal diseases caused by bacteria, fungi and viruses; how diseases make agriculture unprofitable; and the importance of disease resistance in agriculture. Students participate in activities to identify disease symptoms, microorganisms that cause disease, and how diseases spread between animals and humans.