This document summarizes Constantijn van Oranje-Nassau's presentation on startups and innovation in the US and EU. It discusses trends in government, corporations, and universities and how they interact. It then provides lessons learned from the US experience, including the importance of clusters and networks. It outlines strengths and challenges for the Netherlands, and proposes actions for StartupDelta to strengthen the Dutch ecosystem, connect it internationally, and advocate for the future. The goal is to make the Netherlands the best ecosystem in Europe for starting and growing businesses.