This document summarizes a presentation about regional governance and leadership models in three Dutch regions: Brainport Twente, Amsterdam Metropolitan Area, and Brainport Eindhoven. It finds that the regions have different network models for governance based on their history and resources: Brainport Twente uses separate "silos", Brainport Eindhoven a dense "beehive" structure, and Amsterdam a looser "flocks" model. Leadership is sometimes lacking but can be effective if connective, and balance is needed between bottom-up and top-down approaches. Further research on multiple helix strategic networks and their effectiveness is warranted.