This document announces a request for pilot project proposals focused on analyzing the genomics and transcriptomics of rare tumor subtypes and exceptional responders using already available human tissue samples. Funding of $25,000-$50,000 will be provided for around 5-6 projects to analyze available samples and answer clinically relevant questions. The goal is to encourage collaboration and application of genomic technologies at Fox Chase Cancer Center to classify tumors, identify drivers of cancer, and understand treatment response and resistance in order to advance clinical protocols. Proposals are due June 1, 2015 and must not exceed 5 pages excluding references and budgets.