3D navigation systems like the O-arm provide more accurate pedicle screw placement than 2D fluoroscopy or free-hand techniques. Conventional techniques have misplacement rates of 5-55% while 3D navigation achieves over 95% accuracy. The O-arm acquires multi-planar images with less radiation exposure. It also allows for intraoperative correction of misplaced screws. However, 3D navigation has a steep learning curve and can increase operative time. Based on experience with 20 patients, the author achieved no breaches or displacements using O-arm guidance.