2. Objectives
• At the end of this lecture, the students should be able
to
- know the history of spinal anaesthesia
- define spinal anaesthesia
- know the anatomy related to spinal anaesthesia
- know the indications and contraindications of SAB
- perform the technique of SAB
- identify the complications
- solve the complications
- know the factors affecting to the spread of spinal
anaesthesia
- differentiate between spinal and epidural anaesthesia
spinal anesthesia/anesthesiology/184-244 2
3. Advantages of spinal anesthesia
1. Cost. The costs associated with SPA are
minimal.
2. Patient satisfaction. the majority of patients are
very happy with this technique.
3. Respiratory disease. SPA produces few
adverse effects on the respiratory system as
long as unduly high blocks are avoided.
4. Patent airway. As control of the airway is not
compromised, there is a reduced risk of airway
obstruction or the aspiration of gastric
contents.
3
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4. 5. Diabetic patients. There is little risk of unrecognised
hypoglycaemia in an awake patient.
6. Muscle relaxation. SPA provides excellent muscle relaxation
for lower abdominal and lower limb surgery.
7. Bleeding. Blood loss during operation is less than when the
same operation is done under general anaesthesia.
4
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5. 5
8. Splanchnic blood flow. Because of its effect on increasing
blood flow to the gut, spinal anaesthesia reduces the
incidence of anastomotic dehiscence.
9. Visceral tone. The bowel is contracted by SPA and
sphincters relaxed although peristalsis continues. Normal
gut function rapidly returns following surgery.
10. Coagulation. Post-operative deep vein thromboses and
pulmonary emboli are less common following spinal
anaesthesia.
spinal anesthesia/anesthesiology/184-244
6. Spinal Anaesthesia
• Spinal, or sub-arachnoid block is a form of regional anaesthesia
involving the injection of local anaesthetic into the sub-
arachnoid using a fine needle. This produces surgical
anaesthesia to a part of the body.
spinal anesthesia/anesthesiology/184-244 6
7. SPINAL ANAESTHESIA
• Subarachnoid block
• Intrathecal block
• Central neural block
• Definition
Injection of local anesthetic agents into the subarachnoid
space to produce transient motor, sensory & autonomic block.
spinal anesthesia/anesthesiology/184-244 7
8. History
• 1885- Corning USA (dog)
• 1898- August Bier
• 6 patients for lower extremity surgery
• Nausea, vomiting & headache!!
• Received spinal from colleague, Dr Hildebrandt
• Headache!!!
spinal anesthesia/anesthesiology/184-244 8
11. Anatomy 3
• 3 membranes; pia, arachnoid & dura
• Dura outermost layer, to S2,
• Arachnoid also to S2 is middle. Subdural between.
• Sub arachnoid space contains spinal nerves and CSF
• Pia clings to surface of cord
spinal anesthesia/anesthesiology/184-244 11
20. Local Anaesthetics
• Block Na Channels in nerve membrane, thus preventing
progression of Action Potential
• Site of Action – nerve roots and spinal cord
• 4 factors in uptake of local anaesthetic
• Concentration of LA in CSF
• Surface area of nerve tissue exposed to CSF
• Lipid content of nerve tissue
• Blood flow
spinal anesthesia/anesthesiology/184-244 20
21. Local Anaesthetics
• Spinal cord and nerves are mixed nerves
• LA blocks smaller, unmyelinated first , larger myelinated last
• May see variable clinical picture
spinal anesthesia/anesthesiology/184-244 21
22. Nerve sizes
• Aα Motor neurone
• Aδ Sensory, touch & pressure
• C Nocioceptors, temperature
• B preganglionic autononic
• C postganglionic autonomic
spinal anesthesia/anesthesiology/184-244 22
23. Local Anaesthetics
• Cocaine
• Lignocaine (lidocaine) (5% heavy lignocaine )
• Bupivacaine ( 0.5 % heavy bupivacaine )
• Prilocaine
• Tetracaine
spinal anesthesia/anesthesiology/184-244 23
25. Physiological changes in spinal anaesthesia
• CNS
Order of blocking nerve fibres
(1) Autonomic preganglionic B fibre
(2) Temperature fibre (cold before warm)
(3) Pinprink fibre
(4) Fibre conveying pain greater than
pinprick
(5) Touch fibre
(6) Deep pressure fibre
(7) Somatic motor fibre
(8) Fibre conveying vibratory sense and
priopioceptive impulses
spinal anesthesia/anesthesiology/184-244 25
26. • CVS
- Vasodilatation of resistance & capacitance vessels
- Hypotension
- Bradycardia if block above T4
• Respiratory System
- Diaphragm remain uneffected
- Ascending block of intercostals muscle causes difficulty in
breathing
spinal anesthesia/anesthesiology/184-244 26
27. • Viscera
- Gut- small contracted gut with active peristalsis
- Bladder- atonic bladder
• Renal
- RBF& GFR remain uneffected except extreme
hypotension
• Neuroendocrine
- Block the complex neural & hormonal stress
response to surgery
spinal anesthesia/anesthesiology/184-244 27
28. Indications
• Lower limb surgery e.g. ORIF , amputation
• Lower abdominal surgery e.g. appendiectomy ,
hydrocele ,hernia
• Perianal region surgery e.g. pile, fistula , fissure
• Obstetric e.g. LSCS
• Gynecological surgery e.g: TAH ,VH , sterilization
• Urological surgery e.g. TURP ,TVP
spinal anesthesia/anesthesiology/184-244 28
29. Contraindications
• (A) Absolute contraindications
1.Patient refusal
2.Localized infection at the site of injection
3.Generalized infection or septicemia
4.Coagulopathy
5.Increased ICP
6.Severe hypovolemia or shock
7.Fixed cardiac output condition eg: severe
AS
8. Allergic to local anaesthetics
spinal anesthesia/anesthesiology/184-244 29
30. Contraindications
(B) Relative contraindications
1. Localized infection peripheral to the site of
injection
2. Backache
3. Patient taking platelet inhibitory drugs e.g.
aspirin
spinal anesthesia/anesthesiology/184-244 30
31. How to perform the spinal injection?
• Clean the patient’s back with antiseptic.
• Locate a suitable interspinous space.
• Raise an intradermal wheal of LA agent at
proposed puncture site.
31
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32. How to perform the spinal injection? continue
32
Insert the needle: the structures that will be passed skin ,
subcutaneous tissue, supraspinous ligament , interaspinous
ligament , lagementum flavum , epidural space, dura mater,
subdural space, arachnoid matter, and then subarachnoid
space.
When CSF appears then slowly inject the local anesthetic.
spinal anesthesia/anesthesiology/184-244
33. Complications
• Hypotension & bradycardia
- Hypotension - SBP < 90 mmHg or
reduction of BP > 20 % of preoperative
value
- Bradycardia - HR < 60 beats per minute
- Treatment - maintain intravascular volume with NS or RL
- HR < 60 BPM – iv atropine
- HR > 60 BPM – iv ephedrine
- 5 degree head down tilt.
spinal anesthesia/anesthesiology/184-244 33
34. Complications
Dyspnea - reassurance of the patient
- adequate ventilation must be ensured
Apnea - Immediate ventilatory support is
required
Paresthesias - Direct trauma to the spinal
nerve or intraneural injection
spinal anesthesia/anesthesiology/184-244 34
35. Complications
Blood tap - d/t puncture of epidural veins
Tx - needle s/b withdrawn & reinserted
Nausea & vomiting - d/t hypotension or
unopposed vagal
stimulation
Tx - restoration of BP
- administration of oxygen
- iv atropine
- antiemetic - care s/b taken
because it may cause hypotension
spinal anesthesia/anesthesiology/184-244 35
36. Complications
-Post dual puncture headache (PDPH)
- occipital headache
- worsened by patient sitting upright
- improved by lying down
- accompanied by tinitus, blurred vision,
diplopia
- onset is usually 24-48 hours postop
- d/t continuous leak of CSF through the
dura hole which reduce CSF pressure & produce
traction of meningeal vessel & nerve
spinal anesthesia/anesthesiology/184-244 36
37. Treatment of PDPH
- initial conservative treatment include bed rest
and iv fluids & analgesic
- caffeine (300 mg orally ) or caffeine benzoate
(500 mg in 500 ml of NS iv over 2 hours )
- epidural blood patch - placement of 10- 15 ml of
autologus blood into the epidural space if
headache is severe or persist > 24 hrs
- success rate 65%-- 95%
spinal anesthesia/anesthesiology/184-244 37
38. Complications
Backache
- d/t flattening of the normal lumber lordosis
during muscle relaxation with resultant
stretching of joint capsule ligament &
muscle.
- treatment with analgesic & reassurance
Infection - chemical and viral or bacterial
infection
spinal anesthesia/anesthesiology/184-244 38
39. Complications
• Neurological impairment
- m/b direct (e.g. needle trauma)
- toxic ( introduction of chemicals ,virus or bacteria)
- ischemic ( e.g. vascular compromise from compression
by an extra dual hematoma)
- transient radicular irritation (last 2-7 days)
spinal anesthesia/anesthesiology/184-244 39
41. Factors affecting spread of spinal Block
Local Anaesthetic
Baricity
Dose
Volume
Specific Gravity
Patient
Position
Height
Spinal column anatomy
Decreased CSF volume (pregnancy)
spinal anesthesia/anesthesiology/184-244 41
42. Factors affecting spread of spinal Block 2
• Technique
• Site of injection
• Speed
• Bevel direction
• Variability in CSF volume makes accurate prediction of the
level of spinal blockade difficult, even if BMI considered.
spinal anesthesia/anesthesiology/184-244 42
47. Differences between Spinal and Epidural
Anesthesia
47
Spinal anaesthesia Extradural Anaesthesia
Level: below L1/L2, where the spinal cord
ends
Level: at any level of the vertebral column.
Injection: subarachnoid space i.e punture
of the dura mater
Injection: epidural space (between
Ligamentum flavum and dura mater) i.e
without punture of the dura mater
Identification of the subarachnoid space:
When CSF appears
Identification of the Peridural space:
Using the Loss of Resistance technique.
Doses: 2.5- 3.5 ml bupivacaine 0.5%
heavy
Doses: 15- 20 ml bupivacaine 0.5%
Onset of action: rapid (2-5 min) Onset of action: slow (15-20 min)
Density of block: more dense Density of block: less dense
Hypotension: rapid Hypotension: slow
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