Presentation for "Solutions for Open Science" (SOS) 2017-10-12 at the Institut Pasteur https://research.pasteur.fr/fr/event/solutions-for-open-science/

1. Socio-cognitive rehabilitation
in autism spectrum disorders
via human-machine interaction
Guillaume Dumas (gdumas@pasteur.fr)
Human Genetics & Cognitive Functions, Neuroscience Department, Institut Pasteur
SoNeTAA, Child & Adolescent Psychiatry Department, Hôpital Robert-Debré, AP-HP
Solutions for Open Science (SOS) — Institut Pasteur, Paris 2017-10-12

2. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
A long time ago in a journal far,
far away …

3. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
The Haken-Kelso-Bunz model (1985)
3
A theoretical model of phase transitions in human hand movements. Biological Cybernetics, 51, 347 356.

4. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
The Haken-Kelso-Bunz model (1985)
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Phase
Transition

5. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
The Haken-Kelso-Bunz model (1985)
5

6. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
30 years later …

7. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
The Virtual Partner Interaction (Kelso et al. PLoS ONE 2009)
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8. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
The Virtual Partner Interaction (Kelso et al. PLoS ONE 2009)
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9. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
The Virtual Partner Interaction (Kelso et al. PLoS ONE 2009)
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10. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
3 developers later …

11. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
The Virtual Partner Interaction (Kelso et al. PLoS ONE 2009)
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12. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Two-body Neuroscience (Dumas, CIB 2011)
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13. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Human Dynamic Clamp (Dumas et al. PNAS 2014)
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14. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Human Dynamic Clamp (Dumas et al. PNAS 2014)
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15. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Human Dynamic Clamp (Dumas et al. PNAS 2014)
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16. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Human Dynamic Clamp (Dumas et al. PNAS 2014)
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17. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Web-VPI
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18. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Virtual Teacher Interaction (Kostrubiec et al. PLoS ONE 2015)
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19. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Social Neuroscience for Therapeutic Approaches in Autism (SoNeTAA)
19
Comorbidities
intellectual disability
epilepsy
motor control problems
ADHD
Tics
Anxiety
sleep disorders
gastrointestinal problems
Epidemiology
0.7–1.1% of the
population
4/1 male/female ratio

20. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Social Neuroscience for Therapeutic Approaches in Autism (SoNeTAA)
19
Comorbidities
intellectual disability
epilepsy
motor control problems
ADHD
Tics
Anxiety
sleep disorders
gastrointestinal problems
Epidemiology
0.7–1.1% of the
population
4/1 male/female ratio

21. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Social Neuroscience for Therapeutic Approaches in Autism (SoNeTAA)
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~10000
patients/year
>2000 patients with autism/year

22. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Social Neuroscience for Therapeutic Approaches in Autism (SoNeTAA)
20
~10000
patients/year
>2000 patients with autism/year

23. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Social Neuroscience for Therapeutic Approaches in Autism (SoNeTAA)
21

24. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Projet Enjeu Biotech de l’ECP (2015/16)
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25. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Projet Enjeu Biotech de l’ECP (2015/16)
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26. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Projet Enjeu Biotech de l’ECP (2016/17)
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27. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Projet Enjeu Biotech de l’ECP (2016/17)
25

28. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Projet Enjeu Biotech de l’ECP (2016/17)
26

29. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
KATE
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30. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Perspectives
28
Scores
Fixed
product
Game
or
Robot
Commercial
Relationship
Limited
User
Feedback
Game
Design
No
Validation

31. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Perspectives
28
Scores
Fixed
product
Game
or
Robot
Commercial
Relationship
Limited
User
Feedback
Game
Design
No
Validation
Measures
Open
Source
KATE
Sharing Users
feedbacks
Gather Scientific
validation

32. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Perspectives
29
Credit: Louis Pelosse

33. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Perspectives
29
Accessibility Credit: Louis Pelosse

34. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Perspectives
29
Accessibility
Sustainability
Credit: Louis Pelosse

35. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Perspectives
29
Accessibility
Sustainability
Inclusivity
Credit: Louis Pelosse

36. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Perspectives
29
Accessibility
Sustainability
Inclusivity
Credit: Louis Pelosse

37. Socio-Cognitive Rehabilitation in Autism Spectrum Disorders via Human-Machine Interaction
Acknowledgement
30
Old-Paris Team
Jacqueline Nadel
Jacques Martinerie
Robert Soussignan
Mario Chavez
Emeline Mercier
Boca Raton Team
New-Paris Team
Collaborators
Leonhard Schilbach
Eva Loth
Benno Schwikowski
Merle Fairhurst
Danilo Bzdok
Denis Engemann
Benoît Theuil
Thomas Bourgeron
Richard Delorme
Aline Lefebvre
Yang-Min Kim
Roberto Toro
Thomas Rolland
Freddy Cliquet
Anita Beggiato
Alexandre Mathieu
Hany Goubran-BotrosJ.A. Scott Kelso
Emmanuelle Tognoli
Gonzalo DeGuzman
Armin Fuchs
Mengsen Zhang
Viviane Kostrubiec
Alexandre Lehmann
Asaf Bachrach
Julien Laroche
Elvis Dohmatob
Erik Maronde
Albane Imbert