SlideShare a Scribd company logo
1 of 3
Download to read offline
Heart Risk Assessment for Mining Workers in
Papua New Guinea. Summary Paper for Heart
Assessment and Stratification
Arnold Waine*
Division of Surgery, Papua New Guinea
Background/Introduction
Papua New Guinea has about seven active mining and exploration activities for minerals
like gold, copper, and other minor minerals. Each is managed by different company and
together employs about ten thousand workers. A fifth of this would be foreign workers. Most
of the Mine workers that are screened at the Employees Health and Wellness clinics tend to
have similar compounding health risks. As a result, the common diseases that are prevalent
are Hypertension, Diabetic Mellitus, High Cholesterol, general Obesity (BMI>25m2
/Kg) with
minimal to zero level of physical exercise. Despite advice to religiously take the medications,
there is noticeable lack of medication compliance, and a handful are usually under dosages.
While this provides a perfect niche for a cardiovascular disease of varying magnitude,
there is grave concern for those who already developed severe hypertension and insidious
progression to Ischemic Heart Diseases. Sudden myocardial infarction and/or heart attack,
and cerebral vascular accident or stroke. These conditions do not usually provide preceding
alarms, nor does it give you time to prepare, yet the end result is usually a permanent
disability or worse, fatality. Therefore, the overall aim and objective of the Health and Wellness
clinic established by each Mine sites is first to identify those people who are at high risk of
developing heart diseases and initiate early treatment and lifestyle adjustment programs.
Second aim of the clinic is to identify those who already are diagnosed with hypertensive or
other vascular related medical conditions and require ongoing support and treatment. Thirdly
for those with other medical conditions. The majority of the screening are for pre-work health
and or routine follow up. However, for those that are in the second category, special health
programs are initiated and continuous assessment about their condition is measured on a
regular interval. Furthermore, a handful are referred to other major hospitals for specialist
investigations and treatments.
Employee Medical Assessment
The Health and wellness clinic has a standard algorithm that consist of mostly
objective parameters to measure all the compounding factors. Each categorical variable is
given a nominal value to which a summative score is done, and health risk score is given.
The category on the assessment includes age, gender, previous cardiac events, Body Mass
Index BMI, Waist measurement, Blood cholesterol, lipids and glucose levels. Systolic Blood
Pressure (SBP) and Diastolic Blood Pressure (DBP) and mean Arterial Pressure (MAP) are
separately calculated. Physical exercise using Chester scoring system is also incorporated
into the assessment form. Finally, the lifestyle habits like frequency of alcohol intake, smoke
and Betel nut chewing (an area nut known as a stimulate and is used among local people)
makes the final and important list for a major Cardiovascular event. A total score is given, and
the Risk is calculated accordingly. While this medical assessment scoring system provides
guide and assist in decision making on the management of the cases, it lacks specificity on
its measurement on cardiovascular events. The reason is simply because of the dynamic flow
of the blood, contents of the blood, the vascular wall integrity, and specific flow dynamics of
Crimson Publishers
Wings to the Research
Commentary
*Corresponding author: Arnold Waine,
Division of Surgery, Papua New Guinea
Submission: February 24, 2020
Published: August 18, 2020
Volume 3 - Issue 4
How to cite this article: Arnold
Waine. Heart Risk Assessment for
Mining Workers in Papua New Guinea.
Summary Paper for Heart Assessment
and Stratification. Surg Med Open
Acc J.3(4). SMOAJ.000568.2020.
DOI: 10.31031/SMOAJ.2020.03.000568
Copyright@ Arnold Waine, This article is
distributed under the terms of the Creative
Commons Attribution 4.0 International
License, which permits unrestricted use
and redistribution provided that the
original author and source are credited.
ISSN: 2578-0379
1
Surgical Medicine Open Access Journal
2
Surg Med Open Acc J Copyright © Arnold Waine
SMOAJ.MS.ID.000568. 3(4).2020
coronary microvascular during diastole and overall strain on the
myocardium. The Employee Health and Wellness clinics hereby
propose to undertake further cardiovascular screening on high risk
patients to yield increasing sensitivity and specificity on the subject
and furthermore provides equivocal stratification. The combine
algorithm extends to cover areas of bias and chances of hawthorn.
It is the believe of this team that an objective measurable outcome
is truly evaluated. Measurement that are reliable, reproducible and
is easily performed without the need for expensive equipment. The
following are the proposed methods specifically design to focus on
the cardiovascular system of the mine workers in the country.
Measurement
Endothelial glycocalyx
The endothelium cell lining the vascular wall is covered with the
protective glycocalyx. Composed of glycoproteins, proteoglycans,
glycolipids and glycosaminoglycans of hyaluronic acid. The
integrity of this substance plays a vital role in vascular permeability,
inflammation, and elasticity [1,2]. Loss of glycocalyx has been
shown to associate with hyperglycemia, hyperlipidemia, smoking,
high blood pressure, and high sodium [3,4]. Damaged glycocalyx
cumulatively causes impaired vascular elasticity, impaired
coronary flow reserve, and myocardium deformation. Side stream
Dark Field imaging is used to measure the perfused boundary
region (PBR) of the sublingual arterial micro vessels. The thickness
of the Glycocalyx is measured by this imaging using an instrument
called the GlycoCheck. GlycoCheck is being formally adapted as a
method to assess endothelial integrity by the European Society of
Cardiology Working Group on Peripheral Circulation [4,5].
Echocardiography
Echocardiography (Using a Vivid 7 ultrasound system) is
used to measure Left Ventricular myocardial deformation and the
coronary flow reserve. Each of them is described according to the
test done as below.
Left Ventricular myocardial deformation
Longitudinal systolic strain can be measured from standard
2-dimensional acquisition with the use of a dedicated software
application and its Global Longitudinal strain can be measured
from the apical chambers [6].
Coronary flow reserve
Coronary blood flow velocity profiles are usually done solely
by color-guided pulse wave Doppler. And the coronary flow reserve
is calculated as the ratio of peak diastolic velocity to resting peak
diastolic velocity. The average measurement from 3 cardiac cycles
is recorded [7,8].
Arterial stiffness
Arterial Stiffness is measured by Pulse wave velocity (PWV)
using tonometry by Compiler. Two noninvasive pressure sensors
are normally used to record the carotids and femoral waveforms.
The distance between the two is measured using a tape measure.
PWV is calculated as the distance between carotid to femoral site
divided by transit time between waves [9-11]. The evidence from
many studies have clearly demonstrated that, reduced endothelial
glycocalyxthicknessasassessedbythePBR,thereisacorresponding
increase of systolic blood pressure, and an increase Pulse Wave
Velocity which denotes for arterial stiffness. Decrease glycocalyx
is also associated with decreasing coronary flow reserve (CFR). In
one study, multivariable regression analysis of the association of
decreased glycocalyx thickness shows increased PBR, decreased
CFR, and decrease PWV. It remains significant after readjustment of
age, gender, BMI, Smoke, LV Mass, heart rate, hyperlipidemia [12].
Conclusion
This summary paper highlights the need for further assessment
of Mine workers of Papua New Guinea with higher risk of
cardiovascular events with specific screening modalities. This is
to ascertain the myocardial strain and its overall function. To avoid
catastrophic outcomes to the person, family and overall companies’
establishment.
Declaration
Thank you to Dr Turhurus and team for the opportunity given
to me to experience corporate health services and its dynamics
during this time and my former visits. My travels and stay were
all sponsored by the OK Tedi Mining Ltd through its Occupational
Health and Safety division.
References
1.	 Noble MI, Drake HAJ, Vink H (2008) Hypothesis: Arterial glycocalyx
dysfunction is the first step in the atherothrombotic process. QJM 101:
513-518.
2.	 Weinbaum S, Tarbell JM, Damiano ER (2007) The structure and function
of the endothelial glycocalyx layer. Annu Rev Biomed Eng 9: 121-167.
3.	 Max N, Haeften TW, Gouverneur MC, Hans L Mooij, Miriam HPL, et al.
(2006) Loss of endothelial glycocalyx during acute hyperglycemia
coincides with endothelial dysfunction and coagulation activation in
vivo. Diabetes 55(2): 480-486.
4.	 Lekakis J, Abraham P, Balbarini A, Andrew B, Chantal MB, et al. (2011)
Methods for evaluating endothelial function: A position statement
from the European society of cardiology working group on peripheral
circulation. Eur J Cardiovasc Prev Rehabil 18(16): 775-789.
5.	 Mancia G, Fagard R, Narkiewicz K, Michel A, Michel B, et al. (2013) ESH/
ESC Guidelines for the management of arterial hypertension: ESH/ESC
Guidelines for the management of arterial hypertension. Eur Heart J
39(33): 2159-2221.
6.	 Reisner SA, Lysyansky P, Agmon Y, Mutlak D, Lessick J, et al. (2004) Global
longitudinal strain: A novel index of left ventricular systolic function. J
Am Soc Echocardiogr 17(6): 630-633.
7.	 Ikonomidis I, Tzortzis S, Triantafyllidi H, John P, Costas P, et al. (2015)
Association of Impaired left ventricular twisting-untwisting with
vascular dysfunction, nuerohumoral activation and impaired exercise
capacity in hypertensive heart disease. Eur J Heart Fail 17(12): 1240-
1251.
8.	 Ikonomidis I, Lekakis J, Papadopoulos C, Helen T, Ioannis P, et al. (2008)
Incremental value of pulse wave velocity in the determination of
coronary microcirculatory dysfunction in never-treated patients with
essential hypertension. Am J Hypertens 21(7): 806-813.
3
Surg Med Open Acc J Copyright © Arnold Waine
SMOAJ.MS.ID.000568. 3(4).2020
9.	 Ikonomidis I, Ntai K, Kadoglou NP, John P, Ioannis P, et al. (2013) The
evaluation of pulse wave velocity using arteriograph and complior
apparatus across multiple cohorts of cardiovascular-related diseases.
Int J Cardiol 168(5): 4890-4892.
10.	Ikonomidis I, Makavos G, Lekakis J (2015) Arterial stiffness and coronary
artery diseases. Curr Opin Cardiol 30(4): 422-431.
11.	Tritakis V, Tzortzis S, Ikonomidis I, Kleanthi D, Georgios P, et al.
(2016) Asociation of arterial stiffness with coronary flow reserve in
revascularized coronary artery diseases patients. World J Cardiol 8(2):
231-239.
12.	Ignatios I, Astrinos V, Geroge M, George Pavlidis, Dimitris Benas, et al.
(2018) Association of impaired endothelial glycocalyx with arterial
stiffness, coronary microcirculatory dysfunction, and abnormal
myocardial deformation in untreated hypertensives. The Journal of
clinical hypertension 20(4): 672-679.
For possible submissions Click below:
Submit Article

More Related Content

What's hot

Scandinavian Simvastatin Survival Study (4S)
Scandinavian Simvastatin Survival Study (4S)Scandinavian Simvastatin Survival Study (4S)
Scandinavian Simvastatin Survival Study (4S)Zerva
 
Samir rafla a-new-score-of-positivity-in-thallium-studies-of-ischemic-patients
Samir rafla a-new-score-of-positivity-in-thallium-studies-of-ischemic-patientsSamir rafla a-new-score-of-positivity-in-thallium-studies-of-ischemic-patients
Samir rafla a-new-score-of-positivity-in-thallium-studies-of-ischemic-patientsAlexandria University, Egypt
 
The Coagulopathy of Trauma: A Review of Mechanisms
The Coagulopathy of Trauma: A Review of MechanismsThe Coagulopathy of Trauma: A Review of Mechanisms
The Coagulopathy of Trauma: A Review of MechanismsEmergency Live
 
Does Serum Lactate and Central Venous Saturation Predict Perioperative Outcom...
Does Serum Lactate and Central Venous Saturation Predict Perioperative Outcom...Does Serum Lactate and Central Venous Saturation Predict Perioperative Outcom...
Does Serum Lactate and Central Venous Saturation Predict Perioperative Outcom...crimsonpublishersOJCHD
 
Predictor Cardiaco
Predictor CardiacoPredictor Cardiaco
Predictor CardiacoJavier Vidal
 
MI FAQs
MI FAQsMI FAQs
MI FAQsJ Kim
 
Advancing dialysis: Recasting kidney failure as cardiovascular disease
Advancing dialysis: Recasting kidney failure as cardiovascular diseaseAdvancing dialysis: Recasting kidney failure as cardiovascular disease
Advancing dialysis: Recasting kidney failure as cardiovascular diseaseAdvancingDialysis.org
 
accurate monitoring of intravascular fluid volume
accurate monitoring of intravascular fluid volumeaccurate monitoring of intravascular fluid volume
accurate monitoring of intravascular fluid volumePhilip Binkley MD, MPH
 
Pericardial Blood as a Trigger for POAF Affter Cardiac Surgery ~ Annals of Th...
Pericardial Blood as a Trigger for POAF Affter Cardiac Surgery ~ Annals of Th...Pericardial Blood as a Trigger for POAF Affter Cardiac Surgery ~ Annals of Th...
Pericardial Blood as a Trigger for POAF Affter Cardiac Surgery ~ Annals of Th...Paul Molloy
 
Advancing Dialysis Hypertension in Dialysis Patients
Advancing Dialysis Hypertension in Dialysis PatientsAdvancing Dialysis Hypertension in Dialysis Patients
Advancing Dialysis Hypertension in Dialysis PatientsAdvancingDialysis.org
 
12471_2015_Article_733
12471_2015_Article_73312471_2015_Article_733
12471_2015_Article_733Brian Vendel
 
Journal of diabetes research
Journal of diabetes researchJournal of diabetes research
Journal of diabetes researchScidoc Publishers
 
Cardiology: Treatment of Heart Failure
Cardiology: Treatment of Heart FailureCardiology: Treatment of Heart Failure
Cardiology: Treatment of Heart FailureVedica Sethi
 
Lipids and cerebrovascular diseases
Lipids and cerebrovascular diseasesLipids and cerebrovascular diseases
Lipids and cerebrovascular diseasesNeurologyKota
 
Management of severe heart failure in japan heart transplantation and lvad
Management of severe heart failure in japan heart transplantation and lvadManagement of severe heart failure in japan heart transplantation and lvad
Management of severe heart failure in japan heart transplantation and lvaddrucsamal
 
EVALUATING RISK OF HEART FAILURE WITH ERYTHROPOIETIN IN CHRONIC ANEMIA
EVALUATING RISK OF HEART FAILURE WITH ERYTHROPOIETIN IN CHRONIC ANEMIAEVALUATING RISK OF HEART FAILURE WITH ERYTHROPOIETIN IN CHRONIC ANEMIA
EVALUATING RISK OF HEART FAILURE WITH ERYTHROPOIETIN IN CHRONIC ANEMIAPARUL UNIVERSITY
 

What's hot (20)

Scandinavian Simvastatin Survival Study (4S)
Scandinavian Simvastatin Survival Study (4S)Scandinavian Simvastatin Survival Study (4S)
Scandinavian Simvastatin Survival Study (4S)
 
Samir rafla a-new-score-of-positivity-in-thallium-studies-of-ischemic-patients
Samir rafla a-new-score-of-positivity-in-thallium-studies-of-ischemic-patientsSamir rafla a-new-score-of-positivity-in-thallium-studies-of-ischemic-patients
Samir rafla a-new-score-of-positivity-in-thallium-studies-of-ischemic-patients
 
The Coagulopathy of Trauma: A Review of Mechanisms
The Coagulopathy of Trauma: A Review of MechanismsThe Coagulopathy of Trauma: A Review of Mechanisms
The Coagulopathy of Trauma: A Review of Mechanisms
 
Does Serum Lactate and Central Venous Saturation Predict Perioperative Outcom...
Does Serum Lactate and Central Venous Saturation Predict Perioperative Outcom...Does Serum Lactate and Central Venous Saturation Predict Perioperative Outcom...
Does Serum Lactate and Central Venous Saturation Predict Perioperative Outcom...
 
Predictor Cardiaco
Predictor CardiacoPredictor Cardiaco
Predictor Cardiaco
 
MI FAQs
MI FAQsMI FAQs
MI FAQs
 
Advancing dialysis: Recasting kidney failure as cardiovascular disease
Advancing dialysis: Recasting kidney failure as cardiovascular diseaseAdvancing dialysis: Recasting kidney failure as cardiovascular disease
Advancing dialysis: Recasting kidney failure as cardiovascular disease
 
accurate monitoring of intravascular fluid volume
accurate monitoring of intravascular fluid volumeaccurate monitoring of intravascular fluid volume
accurate monitoring of intravascular fluid volume
 
Pericardial Blood as a Trigger for POAF Affter Cardiac Surgery ~ Annals of Th...
Pericardial Blood as a Trigger for POAF Affter Cardiac Surgery ~ Annals of Th...Pericardial Blood as a Trigger for POAF Affter Cardiac Surgery ~ Annals of Th...
Pericardial Blood as a Trigger for POAF Affter Cardiac Surgery ~ Annals of Th...
 
Advancing Dialysis Hypertension in Dialysis Patients
Advancing Dialysis Hypertension in Dialysis PatientsAdvancing Dialysis Hypertension in Dialysis Patients
Advancing Dialysis Hypertension in Dialysis Patients
 
12471_2015_Article_733
12471_2015_Article_73312471_2015_Article_733
12471_2015_Article_733
 
International Journal of Cardiovascular Diseases & Diagnosis
International Journal of Cardiovascular Diseases & DiagnosisInternational Journal of Cardiovascular Diseases & Diagnosis
International Journal of Cardiovascular Diseases & Diagnosis
 
Journal of diabetes research
Journal of diabetes researchJournal of diabetes research
Journal of diabetes research
 
Diabetes journal
Diabetes journalDiabetes journal
Diabetes journal
 
Cardiology: Treatment of Heart Failure
Cardiology: Treatment of Heart FailureCardiology: Treatment of Heart Failure
Cardiology: Treatment of Heart Failure
 
Lipids and cerebrovascular diseases
Lipids and cerebrovascular diseasesLipids and cerebrovascular diseases
Lipids and cerebrovascular diseases
 
e12705.full
e12705.fulle12705.full
e12705.full
 
Management of severe heart failure in japan heart transplantation and lvad
Management of severe heart failure in japan heart transplantation and lvadManagement of severe heart failure in japan heart transplantation and lvad
Management of severe heart failure in japan heart transplantation and lvad
 
EVALUATING RISK OF HEART FAILURE WITH ERYTHROPOIETIN IN CHRONIC ANEMIA
EVALUATING RISK OF HEART FAILURE WITH ERYTHROPOIETIN IN CHRONIC ANEMIAEVALUATING RISK OF HEART FAILURE WITH ERYTHROPOIETIN IN CHRONIC ANEMIA
EVALUATING RISK OF HEART FAILURE WITH ERYTHROPOIETIN IN CHRONIC ANEMIA
 
H1898.full
H1898.fullH1898.full
H1898.full
 

Similar to Smoaj.000568

PREVENTION OF HEART PROBLEM USING ARTIFICIAL INTELLIGENCE
PREVENTION OF HEART PROBLEM USING ARTIFICIAL INTELLIGENCEPREVENTION OF HEART PROBLEM USING ARTIFICIAL INTELLIGENCE
PREVENTION OF HEART PROBLEM USING ARTIFICIAL INTELLIGENCEijaia
 
HPPS : Heart Problem Prediction System using Machine Learning
HPPS : Heart Problem Prediction System using Machine LearningHPPS : Heart Problem Prediction System using Machine Learning
HPPS : Heart Problem Prediction System using Machine LearningNimai Chand Das Adhikari
 
Red blood cell and at this effect of diabetes mil lute
Red blood cell and at this effect of diabetes mil lute Red blood cell and at this effect of diabetes mil lute
Red blood cell and at this effect of diabetes mil lute ScSyed
 
Assessment of the Risk of Myocardial Infarction among Undergraduate Students ...
Assessment of the Risk of Myocardial Infarction among Undergraduate Students ...Assessment of the Risk of Myocardial Infarction among Undergraduate Students ...
Assessment of the Risk of Myocardial Infarction among Undergraduate Students ...Healthcare and Medical Sciences
 
00003246 201506000-00015
00003246 201506000-0001500003246 201506000-00015
00003246 201506000-00015thawasit
 
Luisetto m, luca c, farhan a, ghulam r. sudden death heart pathology a new ...
Luisetto m, luca c, farhan a, ghulam r. sudden death heart pathology   a new ...Luisetto m, luca c, farhan a, ghulam r. sudden death heart pathology   a new ...
Luisetto m, luca c, farhan a, ghulam r. sudden death heart pathology a new ...M. Luisetto Pharm.D.Spec. Pharmacology
 
Thermal Imaging for the Diagnosis of Early Vascular Dysfunctions: A Case Report
Thermal Imaging for the Diagnosis of Early Vascular Dysfunctions: A Case ReportThermal Imaging for the Diagnosis of Early Vascular Dysfunctions: A Case Report
Thermal Imaging for the Diagnosis of Early Vascular Dysfunctions: A Case Reportasclepiuspdfs
 
Mangement of chronic heart failure
Mangement of chronic heart failure Mangement of chronic heart failure
Mangement of chronic heart failure Irfan iftekhar
 
Mangement of chronic heart failure 93432-rephrased
Mangement of chronic heart failure 93432-rephrasedMangement of chronic heart failure 93432-rephrased
Mangement of chronic heart failure 93432-rephrasedIrfan iftekhar
 
Diagnosis of Early Risks, Management of Risks, and Reduction of Vascular Dise...
Diagnosis of Early Risks, Management of Risks, and Reduction of Vascular Dise...Diagnosis of Early Risks, Management of Risks, and Reduction of Vascular Dise...
Diagnosis of Early Risks, Management of Risks, and Reduction of Vascular Dise...asclepiuspdfs
 
1-s2.0-S0002914913019292-main
1-s2.0-S0002914913019292-main1-s2.0-S0002914913019292-main
1-s2.0-S0002914913019292-mainBrian Vendel
 
Interdisciplinary care plan7 class nur3400
Interdisciplinary care plan7 class nur3400Interdisciplinary care plan7 class nur3400
Interdisciplinary care plan7 class nur3400ssuserd93c47
 
Assessment of the Prevalence of Some Cardiovascular Risk Factors among the O...
Assessment of the Prevalence of Some Cardiovascular Risk  Factors among the O...Assessment of the Prevalence of Some Cardiovascular Risk  Factors among the O...
Assessment of the Prevalence of Some Cardiovascular Risk Factors among the O...Scientific Review SR
 
Approach to Peripheral Arterial Disease (PAD)
Approach to Peripheral Arterial Disease (PAD)Approach to Peripheral Arterial Disease (PAD)
Approach to Peripheral Arterial Disease (PAD)DrKetanVagholkar
 
Luisetto m, khan fa, mashori gr (2017) sudden heart pathology a new researc...
Luisetto m, khan fa, mashori gr (2017) sudden heart pathology   a new researc...Luisetto m, khan fa, mashori gr (2017) sudden heart pathology   a new researc...
Luisetto m, khan fa, mashori gr (2017) sudden heart pathology a new researc...M. Luisetto Pharm.D.Spec. Pharmacology
 

Similar to Smoaj.000568 (20)

International Journal of Clinical & Experimental Hypertension
International Journal of Clinical & Experimental HypertensionInternational Journal of Clinical & Experimental Hypertension
International Journal of Clinical & Experimental Hypertension
 
PREVENTION OF HEART PROBLEM USING ARTIFICIAL INTELLIGENCE
PREVENTION OF HEART PROBLEM USING ARTIFICIAL INTELLIGENCEPREVENTION OF HEART PROBLEM USING ARTIFICIAL INTELLIGENCE
PREVENTION OF HEART PROBLEM USING ARTIFICIAL INTELLIGENCE
 
HPPS : Heart Problem Prediction System using Machine Learning
HPPS : Heart Problem Prediction System using Machine LearningHPPS : Heart Problem Prediction System using Machine Learning
HPPS : Heart Problem Prediction System using Machine Learning
 
Prevalence and Risk Factors of Microalbuminuria in Hypertensive Patients of T...
Prevalence and Risk Factors of Microalbuminuria in Hypertensive Patients of T...Prevalence and Risk Factors of Microalbuminuria in Hypertensive Patients of T...
Prevalence and Risk Factors of Microalbuminuria in Hypertensive Patients of T...
 
Red blood cell and at this effect of diabetes mil lute
Red blood cell and at this effect of diabetes mil lute Red blood cell and at this effect of diabetes mil lute
Red blood cell and at this effect of diabetes mil lute
 
Assessment of the Risk of Myocardial Infarction among Undergraduate Students ...
Assessment of the Risk of Myocardial Infarction among Undergraduate Students ...Assessment of the Risk of Myocardial Infarction among Undergraduate Students ...
Assessment of the Risk of Myocardial Infarction among Undergraduate Students ...
 
00003246 201506000-00015
00003246 201506000-0001500003246 201506000-00015
00003246 201506000-00015
 
Luisetto m, luca c, farhan a, ghulam r. sudden death heart pathology a new ...
Luisetto m, luca c, farhan a, ghulam r. sudden death heart pathology   a new ...Luisetto m, luca c, farhan a, ghulam r. sudden death heart pathology   a new ...
Luisetto m, luca c, farhan a, ghulam r. sudden death heart pathology a new ...
 
Sprint 2015 nejm
Sprint 2015 nejmSprint 2015 nejm
Sprint 2015 nejm
 
Thermal Imaging for the Diagnosis of Early Vascular Dysfunctions: A Case Report
Thermal Imaging for the Diagnosis of Early Vascular Dysfunctions: A Case ReportThermal Imaging for the Diagnosis of Early Vascular Dysfunctions: A Case Report
Thermal Imaging for the Diagnosis of Early Vascular Dysfunctions: A Case Report
 
CARDIO docx
CARDIO docxCARDIO docx
CARDIO docx
 
Mangement of chronic heart failure
Mangement of chronic heart failure Mangement of chronic heart failure
Mangement of chronic heart failure
 
Mangement of chronic heart failure 93432-rephrased
Mangement of chronic heart failure 93432-rephrasedMangement of chronic heart failure 93432-rephrased
Mangement of chronic heart failure 93432-rephrased
 
Diagnosis of Early Risks, Management of Risks, and Reduction of Vascular Dise...
Diagnosis of Early Risks, Management of Risks, and Reduction of Vascular Dise...Diagnosis of Early Risks, Management of Risks, and Reduction of Vascular Dise...
Diagnosis of Early Risks, Management of Risks, and Reduction of Vascular Dise...
 
1-s2.0-S0002914913019292-main
1-s2.0-S0002914913019292-main1-s2.0-S0002914913019292-main
1-s2.0-S0002914913019292-main
 
Correlation study between total lipid profile and glycosylated hemoglobin amo...
Correlation study between total lipid profile and glycosylated hemoglobin amo...Correlation study between total lipid profile and glycosylated hemoglobin amo...
Correlation study between total lipid profile and glycosylated hemoglobin amo...
 
Interdisciplinary care plan7 class nur3400
Interdisciplinary care plan7 class nur3400Interdisciplinary care plan7 class nur3400
Interdisciplinary care plan7 class nur3400
 
Assessment of the Prevalence of Some Cardiovascular Risk Factors among the O...
Assessment of the Prevalence of Some Cardiovascular Risk  Factors among the O...Assessment of the Prevalence of Some Cardiovascular Risk  Factors among the O...
Assessment of the Prevalence of Some Cardiovascular Risk Factors among the O...
 
Approach to Peripheral Arterial Disease (PAD)
Approach to Peripheral Arterial Disease (PAD)Approach to Peripheral Arterial Disease (PAD)
Approach to Peripheral Arterial Disease (PAD)
 
Luisetto m, khan fa, mashori gr (2017) sudden heart pathology a new researc...
Luisetto m, khan fa, mashori gr (2017) sudden heart pathology   a new researc...Luisetto m, khan fa, mashori gr (2017) sudden heart pathology   a new researc...
Luisetto m, khan fa, mashori gr (2017) sudden heart pathology a new researc...
 

More from Crimsonpublisherssmoaj (20)

Smoaj.000583
Smoaj.000583Smoaj.000583
Smoaj.000583
 
Smoaj.000582
Smoaj.000582Smoaj.000582
Smoaj.000582
 
Smoaj.000581
Smoaj.000581Smoaj.000581
Smoaj.000581
 
Smoaj.000580
Smoaj.000580Smoaj.000580
Smoaj.000580
 
Smoaj.000579
Smoaj.000579Smoaj.000579
Smoaj.000579
 
Smoaj.000578
Smoaj.000578Smoaj.000578
Smoaj.000578
 
Smoaj.000577
Smoaj.000577Smoaj.000577
Smoaj.000577
 
Smoaj.000573
Smoaj.000573Smoaj.000573
Smoaj.000573
 
Smoaj.000572
Smoaj.000572Smoaj.000572
Smoaj.000572
 
Smoaj.000571
Smoaj.000571Smoaj.000571
Smoaj.000571
 
Smoaj.000570
Smoaj.000570Smoaj.000570
Smoaj.000570
 
Smoaj.000569
Smoaj.000569Smoaj.000569
Smoaj.000569
 
Smoaj.000567
Smoaj.000567Smoaj.000567
Smoaj.000567
 
Smoaj.000566
Smoaj.000566Smoaj.000566
Smoaj.000566
 
Smoaj.000565
Smoaj.000565Smoaj.000565
Smoaj.000565
 
Smoaj.000564
Smoaj.000564Smoaj.000564
Smoaj.000564
 
Smoaj.000563
Smoaj.000563Smoaj.000563
Smoaj.000563
 
Smoaj.000562
Smoaj.000562Smoaj.000562
Smoaj.000562
 
Smoaj.000561
Smoaj.000561Smoaj.000561
Smoaj.000561
 
Smoaj.000560
Smoaj.000560Smoaj.000560
Smoaj.000560
 

Recently uploaded

Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...Call Girls in Nagpur High Profile
 
VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore EscortsVIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escortsaditipandeya
 
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service Kochi
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service KochiLow Rate Call Girls Kochi Anika 8250192130 Independent Escort Service Kochi
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service KochiSuhani Kapoor
 
High Profile Call Girls Coimbatore Saanvi☎️ 8250192130 Independent Escort Se...
High Profile Call Girls Coimbatore Saanvi☎️  8250192130 Independent Escort Se...High Profile Call Girls Coimbatore Saanvi☎️  8250192130 Independent Escort Se...
High Profile Call Girls Coimbatore Saanvi☎️ 8250192130 Independent Escort Se...narwatsonia7
 
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...Taniya Sharma
 
Call Girls Service Navi Mumbai Samaira 8617697112 Independent Escort Service ...
Call Girls Service Navi Mumbai Samaira 8617697112 Independent Escort Service ...Call Girls Service Navi Mumbai Samaira 8617697112 Independent Escort Service ...
Call Girls Service Navi Mumbai Samaira 8617697112 Independent Escort Service ...Call girls in Ahmedabad High profile
 
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...Arohi Goyal
 
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...astropune
 
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...Dipal Arora
 
Call Girls Nagpur Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Nagpur Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Nagpur Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Nagpur Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...indiancallgirl4rent
 
Call Girl Number in Panvel Mumbai📲 9833363713 💞 Full Night Enjoy
Call Girl Number in Panvel Mumbai📲 9833363713 💞 Full Night EnjoyCall Girl Number in Panvel Mumbai📲 9833363713 💞 Full Night Enjoy
Call Girl Number in Panvel Mumbai📲 9833363713 💞 Full Night Enjoybabeytanya
 
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...CALL GIRLS
 
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...narwatsonia7
 
Premium Call Girls Cottonpet Whatsapp 7001035870 Independent Escort Service
Premium Call Girls Cottonpet Whatsapp 7001035870 Independent Escort ServicePremium Call Girls Cottonpet Whatsapp 7001035870 Independent Escort Service
Premium Call Girls Cottonpet Whatsapp 7001035870 Independent Escort Servicevidya singh
 
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 

Recently uploaded (20)

Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
 
VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore EscortsVIP Call Girls Indore Kirti 💚😋  9256729539 🚀 Indore Escorts
VIP Call Girls Indore Kirti 💚😋 9256729539 🚀 Indore Escorts
 
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service Kochi
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service KochiLow Rate Call Girls Kochi Anika 8250192130 Independent Escort Service Kochi
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service Kochi
 
High Profile Call Girls Coimbatore Saanvi☎️ 8250192130 Independent Escort Se...
High Profile Call Girls Coimbatore Saanvi☎️  8250192130 Independent Escort Se...High Profile Call Girls Coimbatore Saanvi☎️  8250192130 Independent Escort Se...
High Profile Call Girls Coimbatore Saanvi☎️ 8250192130 Independent Escort Se...
 
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...
 
Call Girls Service Navi Mumbai Samaira 8617697112 Independent Escort Service ...
Call Girls Service Navi Mumbai Samaira 8617697112 Independent Escort Service ...Call Girls Service Navi Mumbai Samaira 8617697112 Independent Escort Service ...
Call Girls Service Navi Mumbai Samaira 8617697112 Independent Escort Service ...
 
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
 
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
 
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
 
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
 
Call Girls Nagpur Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Nagpur Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Nagpur Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Nagpur Just Call 9907093804 Top Class Call Girl Service Available
 
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...
(Rocky) Jaipur Call Girl - 9521753030 Escorts Service 50% Off with Cash ON De...
 
Call Girl Number in Panvel Mumbai📲 9833363713 💞 Full Night Enjoy
Call Girl Number in Panvel Mumbai📲 9833363713 💞 Full Night EnjoyCall Girl Number in Panvel Mumbai📲 9833363713 💞 Full Night Enjoy
Call Girl Number in Panvel Mumbai📲 9833363713 💞 Full Night Enjoy
 
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...
Call Girls Service Surat Samaira ❤️🍑 8250192130 👄 Independent Escort Service ...
 
Russian Call Girls in Delhi Tanvi ➡️ 9711199012 💋📞 Independent Escort Service...
Russian Call Girls in Delhi Tanvi ➡️ 9711199012 💋📞 Independent Escort Service...Russian Call Girls in Delhi Tanvi ➡️ 9711199012 💋📞 Independent Escort Service...
Russian Call Girls in Delhi Tanvi ➡️ 9711199012 💋📞 Independent Escort Service...
 
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...
 
Premium Call Girls Cottonpet Whatsapp 7001035870 Independent Escort Service
Premium Call Girls Cottonpet Whatsapp 7001035870 Independent Escort ServicePremium Call Girls Cottonpet Whatsapp 7001035870 Independent Escort Service
Premium Call Girls Cottonpet Whatsapp 7001035870 Independent Escort Service
 
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available
 

Smoaj.000568

  • 1. Heart Risk Assessment for Mining Workers in Papua New Guinea. Summary Paper for Heart Assessment and Stratification Arnold Waine* Division of Surgery, Papua New Guinea Background/Introduction Papua New Guinea has about seven active mining and exploration activities for minerals like gold, copper, and other minor minerals. Each is managed by different company and together employs about ten thousand workers. A fifth of this would be foreign workers. Most of the Mine workers that are screened at the Employees Health and Wellness clinics tend to have similar compounding health risks. As a result, the common diseases that are prevalent are Hypertension, Diabetic Mellitus, High Cholesterol, general Obesity (BMI>25m2 /Kg) with minimal to zero level of physical exercise. Despite advice to religiously take the medications, there is noticeable lack of medication compliance, and a handful are usually under dosages. While this provides a perfect niche for a cardiovascular disease of varying magnitude, there is grave concern for those who already developed severe hypertension and insidious progression to Ischemic Heart Diseases. Sudden myocardial infarction and/or heart attack, and cerebral vascular accident or stroke. These conditions do not usually provide preceding alarms, nor does it give you time to prepare, yet the end result is usually a permanent disability or worse, fatality. Therefore, the overall aim and objective of the Health and Wellness clinic established by each Mine sites is first to identify those people who are at high risk of developing heart diseases and initiate early treatment and lifestyle adjustment programs. Second aim of the clinic is to identify those who already are diagnosed with hypertensive or other vascular related medical conditions and require ongoing support and treatment. Thirdly for those with other medical conditions. The majority of the screening are for pre-work health and or routine follow up. However, for those that are in the second category, special health programs are initiated and continuous assessment about their condition is measured on a regular interval. Furthermore, a handful are referred to other major hospitals for specialist investigations and treatments. Employee Medical Assessment The Health and wellness clinic has a standard algorithm that consist of mostly objective parameters to measure all the compounding factors. Each categorical variable is given a nominal value to which a summative score is done, and health risk score is given. The category on the assessment includes age, gender, previous cardiac events, Body Mass Index BMI, Waist measurement, Blood cholesterol, lipids and glucose levels. Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) and mean Arterial Pressure (MAP) are separately calculated. Physical exercise using Chester scoring system is also incorporated into the assessment form. Finally, the lifestyle habits like frequency of alcohol intake, smoke and Betel nut chewing (an area nut known as a stimulate and is used among local people) makes the final and important list for a major Cardiovascular event. A total score is given, and the Risk is calculated accordingly. While this medical assessment scoring system provides guide and assist in decision making on the management of the cases, it lacks specificity on its measurement on cardiovascular events. The reason is simply because of the dynamic flow of the blood, contents of the blood, the vascular wall integrity, and specific flow dynamics of Crimson Publishers Wings to the Research Commentary *Corresponding author: Arnold Waine, Division of Surgery, Papua New Guinea Submission: February 24, 2020 Published: August 18, 2020 Volume 3 - Issue 4 How to cite this article: Arnold Waine. Heart Risk Assessment for Mining Workers in Papua New Guinea. Summary Paper for Heart Assessment and Stratification. Surg Med Open Acc J.3(4). SMOAJ.000568.2020. DOI: 10.31031/SMOAJ.2020.03.000568 Copyright@ Arnold Waine, This article is distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use and redistribution provided that the original author and source are credited. ISSN: 2578-0379 1 Surgical Medicine Open Access Journal
  • 2. 2 Surg Med Open Acc J Copyright © Arnold Waine SMOAJ.MS.ID.000568. 3(4).2020 coronary microvascular during diastole and overall strain on the myocardium. The Employee Health and Wellness clinics hereby propose to undertake further cardiovascular screening on high risk patients to yield increasing sensitivity and specificity on the subject and furthermore provides equivocal stratification. The combine algorithm extends to cover areas of bias and chances of hawthorn. It is the believe of this team that an objective measurable outcome is truly evaluated. Measurement that are reliable, reproducible and is easily performed without the need for expensive equipment. The following are the proposed methods specifically design to focus on the cardiovascular system of the mine workers in the country. Measurement Endothelial glycocalyx The endothelium cell lining the vascular wall is covered with the protective glycocalyx. Composed of glycoproteins, proteoglycans, glycolipids and glycosaminoglycans of hyaluronic acid. The integrity of this substance plays a vital role in vascular permeability, inflammation, and elasticity [1,2]. Loss of glycocalyx has been shown to associate with hyperglycemia, hyperlipidemia, smoking, high blood pressure, and high sodium [3,4]. Damaged glycocalyx cumulatively causes impaired vascular elasticity, impaired coronary flow reserve, and myocardium deformation. Side stream Dark Field imaging is used to measure the perfused boundary region (PBR) of the sublingual arterial micro vessels. The thickness of the Glycocalyx is measured by this imaging using an instrument called the GlycoCheck. GlycoCheck is being formally adapted as a method to assess endothelial integrity by the European Society of Cardiology Working Group on Peripheral Circulation [4,5]. Echocardiography Echocardiography (Using a Vivid 7 ultrasound system) is used to measure Left Ventricular myocardial deformation and the coronary flow reserve. Each of them is described according to the test done as below. Left Ventricular myocardial deformation Longitudinal systolic strain can be measured from standard 2-dimensional acquisition with the use of a dedicated software application and its Global Longitudinal strain can be measured from the apical chambers [6]. Coronary flow reserve Coronary blood flow velocity profiles are usually done solely by color-guided pulse wave Doppler. And the coronary flow reserve is calculated as the ratio of peak diastolic velocity to resting peak diastolic velocity. The average measurement from 3 cardiac cycles is recorded [7,8]. Arterial stiffness Arterial Stiffness is measured by Pulse wave velocity (PWV) using tonometry by Compiler. Two noninvasive pressure sensors are normally used to record the carotids and femoral waveforms. The distance between the two is measured using a tape measure. PWV is calculated as the distance between carotid to femoral site divided by transit time between waves [9-11]. The evidence from many studies have clearly demonstrated that, reduced endothelial glycocalyxthicknessasassessedbythePBR,thereisacorresponding increase of systolic blood pressure, and an increase Pulse Wave Velocity which denotes for arterial stiffness. Decrease glycocalyx is also associated with decreasing coronary flow reserve (CFR). In one study, multivariable regression analysis of the association of decreased glycocalyx thickness shows increased PBR, decreased CFR, and decrease PWV. It remains significant after readjustment of age, gender, BMI, Smoke, LV Mass, heart rate, hyperlipidemia [12]. Conclusion This summary paper highlights the need for further assessment of Mine workers of Papua New Guinea with higher risk of cardiovascular events with specific screening modalities. This is to ascertain the myocardial strain and its overall function. To avoid catastrophic outcomes to the person, family and overall companies’ establishment. Declaration Thank you to Dr Turhurus and team for the opportunity given to me to experience corporate health services and its dynamics during this time and my former visits. My travels and stay were all sponsored by the OK Tedi Mining Ltd through its Occupational Health and Safety division. References 1. Noble MI, Drake HAJ, Vink H (2008) Hypothesis: Arterial glycocalyx dysfunction is the first step in the atherothrombotic process. QJM 101: 513-518. 2. Weinbaum S, Tarbell JM, Damiano ER (2007) The structure and function of the endothelial glycocalyx layer. Annu Rev Biomed Eng 9: 121-167. 3. Max N, Haeften TW, Gouverneur MC, Hans L Mooij, Miriam HPL, et al. (2006) Loss of endothelial glycocalyx during acute hyperglycemia coincides with endothelial dysfunction and coagulation activation in vivo. Diabetes 55(2): 480-486. 4. Lekakis J, Abraham P, Balbarini A, Andrew B, Chantal MB, et al. (2011) Methods for evaluating endothelial function: A position statement from the European society of cardiology working group on peripheral circulation. Eur J Cardiovasc Prev Rehabil 18(16): 775-789. 5. Mancia G, Fagard R, Narkiewicz K, Michel A, Michel B, et al. (2013) ESH/ ESC Guidelines for the management of arterial hypertension: ESH/ESC Guidelines for the management of arterial hypertension. Eur Heart J 39(33): 2159-2221. 6. Reisner SA, Lysyansky P, Agmon Y, Mutlak D, Lessick J, et al. (2004) Global longitudinal strain: A novel index of left ventricular systolic function. J Am Soc Echocardiogr 17(6): 630-633. 7. Ikonomidis I, Tzortzis S, Triantafyllidi H, John P, Costas P, et al. (2015) Association of Impaired left ventricular twisting-untwisting with vascular dysfunction, nuerohumoral activation and impaired exercise capacity in hypertensive heart disease. Eur J Heart Fail 17(12): 1240- 1251. 8. Ikonomidis I, Lekakis J, Papadopoulos C, Helen T, Ioannis P, et al. (2008) Incremental value of pulse wave velocity in the determination of coronary microcirculatory dysfunction in never-treated patients with essential hypertension. Am J Hypertens 21(7): 806-813.
  • 3. 3 Surg Med Open Acc J Copyright © Arnold Waine SMOAJ.MS.ID.000568. 3(4).2020 9. Ikonomidis I, Ntai K, Kadoglou NP, John P, Ioannis P, et al. (2013) The evaluation of pulse wave velocity using arteriograph and complior apparatus across multiple cohorts of cardiovascular-related diseases. Int J Cardiol 168(5): 4890-4892. 10. Ikonomidis I, Makavos G, Lekakis J (2015) Arterial stiffness and coronary artery diseases. Curr Opin Cardiol 30(4): 422-431. 11. Tritakis V, Tzortzis S, Ikonomidis I, Kleanthi D, Georgios P, et al. (2016) Asociation of arterial stiffness with coronary flow reserve in revascularized coronary artery diseases patients. World J Cardiol 8(2): 231-239. 12. Ignatios I, Astrinos V, Geroge M, George Pavlidis, Dimitris Benas, et al. (2018) Association of impaired endothelial glycocalyx with arterial stiffness, coronary microcirculatory dysfunction, and abnormal myocardial deformation in untreated hypertensives. The Journal of clinical hypertension 20(4): 672-679. For possible submissions Click below: Submit Article