- The patient is a 63-year-old woman who fell and injured her right hip one month ago. She felt pain in her right groin that worsened with movement. X-rays showed a Garden type 3 fracture of the right femoral neck.
- The patient was treated with IV fluids, analgesics, skin traction with a 3kg load, and was referred to an orthopedic surgeon. She was diagnosed with a closed, displaced fracture of the right femoral neck.
- Surgical treatment options for femoral neck fractures include closed or open reduction with internal fixation for younger patients or hemiarthroplasty or total hip arthroplasty for elderly patients. Complications can include nonunion, avascular necrosis, and hip
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- Non-Displaced Radial and Ulnar Fractures
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- Monteggia Fracture
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263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
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Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
1. Neck Femur Fracture
Resident :
Dr. Putu Acarya Nugraha
Dr. Ardian Mario
Dr. Timothy Alexander
Dr. Zulkifli
Supervisor :
Dr. Fadlyansah Farid, MARS, Sp.OT
2. Name : Mrs. H
Age : 63 years old
Registration : 0001959
Identity
3. Chief Complain : Pain at right groin
Suffered since 1 month ago before being admitted to Wahidin
Sudirohusodo General Hospital. The patient fell while walking on a
slippery floor with the right hip hitting the floor first. The pain is felt
continuously and worsens when the leg is moved and relieved with
rest. After the accident, the patient was unable to stand and walk.
Before the incident, the patient can walk normally without
assistance. The patient then taken to Hasanudin University Hospital
1 week after the accident. A radiological examination was carried
out, and analgesic was given. The surgery was planned but the
patient and family refused. The patient then come to Wahidin
Sudirohusodo General Hospital for further treatment and agree to
do the surgery
History Taking
4. There was no history of loss of consciousness
There was no history of going to bone setter
There was no history of diabetes mellitus and hypertension
History Taking
6. Clinical Findings
Look : Deformity (+), Swelling (-), Hematoma (-), Wound (-)
Feel : Tenderness (+)
Move : Active and passive movement of hip joint can not be
evaluated due to pain
NVD : Sensory is good
Pulsation of dorsalis pedis and posterior tibialis arteries
are palpable. Capillary refill time < 2 seconds.
13. CREDITS: This presentation template was created by Slidesgo, including
icons by Flaticon and infographics & images by Freepik
DISCUSSION
14. Introduction
Stress fractures of the femoral neck are uncommon injuries.
In general, these injuries occur in 2 distinct populations:
• (1) young, active individuals with unaccustomed
strenuous activity or changes in activity, such as runners
or endurance athletes, and
• (2) elderly individuals with osteoporosis. Elderly
individuals may also sustain femoral neck stress fractures
15. Epidemiology
Ref:1. Coon MS, Best BJ. Distal Femur Fractures. [Updated 2022 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan.
250.000 hip
fractures
50% involve
the femoral
neck
80% in women
(esp. age>30y)
Young patients : very low
(high-energy trauma)
Elderly (72 years) : majority
(low-energy falls)
16. Risk Factors
Ref:1. Coon MS, Best BJ. Distal Femur Fractures. [Updated 2022 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan.
female sex white race
increasing
age
poor health tobacco alcohol use
fall history
low
estrogen
level
previous
fracture
17. Anatomy
Egol KA, Koval KJ, Zuckerman JD. Handbook of fractures. Sixth edition. Philadelphia: Wolters Kluwer; 2020. 1 p
Thompson JC, Netter FH. Netter’s concise orthopaedic anatomy. 2nd ed. Philadelphia, PA: Saunders Elsevier; 2010. 404 p.
18. Anatomy
Egol KA, Koval KJ, Zuckerman JD. Handbook of fractures. Sixth edition. Philadelphia: Wolters Kluwer; 2020. 1 p
Thompson JC, Netter FH. Netter’s concise orthopaedic anatomy. 2nd ed. Philadelphia, PA: Saunders Elsevier; 2010. 404 p.
19. MECHANISM OF
INJURY/BIOMECHANICS
Egol KA, Koval KJ, Zuckerman JD. Handbook of fractures. Sixth edition. Philadelphia: Wolters Kluwer; 2020. 1 p
• Most common in older patients.
• Direct : A fall onto the greater trochanter or forced
external rotation of the lower extremity.
• Indirect : Muscle forces overwhelm the strength of the
femoral neck.
Low-energy
trauma
• Accounts for femoral neck fractures in both younger and
older patients, such as motor vehicle accident or fall from
a significant height.
High-energy
trauma
• These are seen in athletes, military recruits, and ballet
dancers.
Cyclical
loading-stress
fractures
• Patients with osteoporosis and osteopenia are at
particular risk.
Insufficiency
fractures
20. CLASSIFICATION
Garden Fracture Classification
• Garden grade I : incomplete femoral neck
fracture, with valgus impaction
• Garden grade II : complete but non-displaced
fracture
• Garden grade III : complete and partially
displaced fracture with alignment of the femoral
neck relative to the neck in varus deformity
• Garden grade IV : complete fracture with
complete displacement.
21. CLASSIFICATION
Pauwel Classification
This is based on the angle of
fracture from the horizontal
• Type I:<30 degrees
• Type II: 31 to 70 degrees
• Type III: >70 degrees
Increasing shear forces with
increasing angle leads to more
fracture instability.
22. DIAGNOSIS
HISTORY
SYMPTOMS
Egol, K dkk. Femoral Neck Fractures; Handbook of Fractures, 5th Ed. Lippincott Williams & Wilkins, 2015. Hal: 349.
Solomon, L dkk. Fractures of the Femoral Neck; Apley’s System of Orthopaedic and Fractures, 9th Ed. Arnold, 2010. Hal: 847.
acute onset of
hip pain
inability to
ambulate
Mechanism of injury
• low-energy
• higher-energy
Antecedent hip pain
• presence of OA or pathological fracture
23. Physical Examination
DIAGNOSIS
• LOOK : deformities, swelling, hematoma, shortening, wound
• FEEL: Pressure sores, examination of the skin and overlying soft
tissues, neurovascular distal
• MOVE: may find it difficult to move and a fracture should be
suspected it here is pain that creates limitations.
Measurement
Leg Length Discrepancy
- True leg length
- Apparent leg length
Rex, C. Examination of Patient withBone and Joint Injuries; Clinical Assessment and Examination in Orthopedics, 2nd Ed. Jaypee Brothers Medical, 2012. Hal: 17-21.
24. DIAGNOSIS
X-RAY: Anteroposterior
(AP) pelvic x-ray and
proximal femoral x-ray in
AP and lateral.
CT scan
Magnetic resonance
imaging (MRI)
Egol, K dkk. Femoral Neck Fractures; Handbook of Fractures, 5th Ed. Lippincott Williams & Wilkins, 2015. Hal: 349.
Solomon, L dkk. Fractures of the Femoral Neck; Apley’s System of Orthopaedic and Fractures, 9th Ed. Arnold, 2010. Hal: 847.
IMAGING
25. TREATMENT
Fracture management
01
Recognition
Know and asses the
fracture
02
03
04
Rehabilitation
Aims to restore
functional activities
as much as possible
Retention
Immobilize the
Fracture
Reduction
Closed reduction &
Open reduction
Rasjad, C. 2015. "Pengantar Ilmu Bedah Orthopedi ed.4 ". PT. Yarsif Watampone, Jakarta. Pp: 340-349
26. TREATMENT
NON - OPERATIVE
Indication :
• extreme medical risk for surgery
• demented non-ambulators who have minimal hip pain.
Early bed to chair mobilization is essential to avoid increased risks and complications
of prolonged recumbency, including :
• poor pulmonary toilet,
• atelectasis,
• venous stasis, and
• pressure ulceration
Egol KA, Koval KJ, Zuckerman JD. Handbook of fractures. Sixth edition. Philadelphia: Wolters Kluwer; 2020. 1 p
Ref:1. Coon MS, Best BJ. Distal Femur Fractures. [Updated 2022 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan.
27. TREATMENT
OPERATIVE
Young patients : emergent open reduction internal
fixation.
Non-displaced fractures : percutaneous cannulated
screws or a sliding hip screw.
Ref:1. Coon MS, Best BJ. Distal Femur Fractures. [Updated 2022 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan.
Displaced fractures in elderly patients :
• Less active individuals may receive a hemiarthroplasty.
• More active individuals are treated with total hip
arthroplasty.
28. COMPLICATION
• Avascular Necrosis
• Non-Union
1."Femoral Neck Fractures: A Review of Current Management" by Robert V. O'Toole, MD, and Michael J. Archdeacon, MD, JBJS Reviews, 2015.
2."Hip Fractures in Adults" by Jeffrey N. Katz, MD, and Jonathan D. Adachi, MD, New England Journal of Medicine, 2021.
29. PROGNOSIS
• The prognosis of a femoral neck fracture depends on several factors,
• In general, femoral neck fractures have a high risk of complications such as
• non-union
• avascular necrosis
• and hip arthritis.
• Studies have shown that the overall success rate of femoral neck fracture surgery is
approximately 80-90%.
• However, some patients may experience complications or require additional surgeries or
interventions.
1."Femoral Neck Fractures: Epidemiology, Classification, Management, and Outcomes" by Robert V. O'Toole, MD, and Michael J. Archdeacon, MD, Journal of Orthopaedic
Trauma, 2014.
2."Hip Fractures in Older Adults: A Clinical Review" by Sarah D. Berry, MD, MPH, and Douglas P. Kiel, MD, MPH, JAMA, 2019.
3.Karim L, Heard S, Maynard M, Rossiter N. The effectiveness of a multidisciplinary hip fracture care model in reducing the incidence of second hip fractures in the elderly.
30. CREDITS: This presentation template was created by Slidesgo, including
icons by Flaticon and infographics & images by Freepik
Thank You
Editor's Notes
■ More than 250,000 hip fractures occur globally each year, 50% involve the femoral neck
■ Eighty percent occur in women, especially age >30 years.
The incidence in younger patients is very low and is associated mainly with high-energy trauma.
The majority occur in the elderly (average age of 72 years) as a result of low-energy falls.
■ Risk factors include female sex, white race, increasing age, poor health, tobacco and alcohol use, previous fracture, fall history, and low estrogen level.
■ More than 250,000 hip fractures occur globally each year, 50% involve the femoral neck
■ Eighty percent occur in women, especially age >30 years.
The incidence in younger patients is very low and is associated mainly with high-energy trauma.
The majority occur in the elderly (average age of 72 years) as a result of low-energy falls.
■ Risk factors include female sex, white race, increasing age, poor health, tobacco and alcohol use, previous fracture, fall history, and low estrogen level.
Ref:Thompson, Jon C. Netter's Concise Atlas of Orthopaedic Anatomy. Teterboro, NJ :Icon Learning Systems, 2002. APA. Thompson, Jon C. (2002)
Ref:Thompson, Jon C. Netter's Concise Atlas of Orthopaedic Anatomy. Teterboro, NJ :Icon Learning Systems, 2002. APA. Thompson, Jon C. (2002)
Non-operative treatment for traumatic fractures is indicated only for patients who are at extreme medical risk for surgery; it may also be considered for demented non-ambulators who have minimal hip pain.
Early bed to chair mobilization is essential to avoid increased risks and complications of prolonged recumbency, including poor pulmonary toilet, atelectasis, venous stasis, and pressure ulceration
Young patients with femoral neck fractures will require treatment with emergent open reduction internal fixation.
Non-displaced fractures are treated typically with percutaneous cannulated screws or a sliding hip screw.
With displaced fractures of the femoral neck in elderly patients, the treatment depends on the patient's baseline activity level and age.
Less active individuals may receive a hemiarthroplasty.
More active individuals are treated with total hip arthroplasty. Total hip arthroplasty is a more resilient procedure, but it also carries an increased risk of dislocation when compared to a hemiarthroplasty.
The prognosis of a femoral neck fracture depends on several factors, including the age and overall health of the patient, the severity of the fracture, and the type of treatment received.
In general, femoral neck fractures have a high risk of complications such as non-union (failure of the bone to heal), avascular necrosis (death of bone tissue due to a lack of blood supply), and hip arthritis. These complications can lead to long-term disability and reduced quality of life.
However, with timely and appropriate treatment, such as surgery to repair the fracture or replace the hip joint, the prognosis can be improved. Physical therapy and rehabilitation are also important for restoring mobility and function after a femoral neck fracture.
Studies have shown that the overall success rate of femoral neck fracture surgery is approximately 80-90%, with the majority of patients experiencing significant improvement in pain, mobility, and quality of life. However, some patients may experience complications or require additional surgeries or interventions.
The prognosis after femoral neck fracture surgery can vary depending on several factors, including the patient's age and overall health, the severity and type of the fracture, the type of surgery performed, and the postoperative rehabilitation program.
Generally, surgery for femoral neck fractures aims to realign and stabilize the broken bones to promote healing and restore normal function. However, there is a risk of complications such as infection, blood clots, and implant failure.
Studies have shown that the overall success rate of femoral neck fracture surgery is approximately 80-90%, with the majority of patients experiencing significant improvement in pain, mobility, and quality of life. However, some patients may experience complications or require additional surgeries or interventions.
The long-term prognosis after femoral neck fracture surgery can also be influenced by factors such as the development of osteoarthritis or avascular necrosis of the femoral head, which can lead to chronic pain and disability.
Rehabilitation after surgery is crucial for optimizing outcomes and preventing complications. Physical therapy and exercise programs can help patients regain strength, flexibility, and mobility, and reduce the risk of falls and future fractures