KPL launching two renown dermatological products in Bangladesh pharma market named "Derson" containing Betamethasone USP 0.1% and "Derson-CL" containing combination of Betamethasone USP 0.1% with Clotrimazole 1%. Betamethasone is a potent topical corticosteroid with anti-inflammatory & antipruritic actions. Clotrimazole is a broad-spectrum antifungal agent.
What is eczema?
Eczema (Dermatitis)-
A particular type of inflammatory reaction of the skin in which there is erythema (reddening), edema (swelling), papules (bumps), and crusting of the skin followed, finally, by lichenification (thickening) and scaling of the skin.
Eczema characteristically causes itching and burning of the skin.
What Causes eczema?
Allergy- One of the commonest cause of Eczema. Triggers include Dust, detergents, rubber, nickel plated jewelry etc.
Environment- More likely in urban areas due to high pollution levels. Extremely dry or cold weather tends to make skin scratchy, resulting in eczema.
Obesity- Obese children are 3 times more likely to get eczema. Obesity results in inflammation of fat tissues that spills into other parts of the body. Excess fat also results in poor circulation and skin ailments.
Smoking- One of the leading causes, especially on the fingers that hold the cigarettes, as well as lips.
Stress- Physical or emotional stress has been known to cause enhanced sensitivity and inflammatory skin changes.
Diaper rash- In babies eczema occurs because of chemical effect of urine/faeces on sensitive skin.
Genetic influence- More likely in individuals with a family history of Eczema or other allergic conditions like Asthma, Hay fever, etc.
this ppt includes Minor ailments include common conditions such as dry skin, rashes, urticarial, skin trauma (cuts/scratches, scrapes, bruises), skin irritations (red, bumpy, scaly, itchy patches of skin, blisters).
What is eczema?
Eczema (Dermatitis)-
A particular type of inflammatory reaction of the skin in which there is erythema (reddening), edema (swelling), papules (bumps), and crusting of the skin followed, finally, by lichenification (thickening) and scaling of the skin.
Eczema characteristically causes itching and burning of the skin.
What Causes eczema?
Allergy- One of the commonest cause of Eczema. Triggers include Dust, detergents, rubber, nickel plated jewelry etc.
Environment- More likely in urban areas due to high pollution levels. Extremely dry or cold weather tends to make skin scratchy, resulting in eczema.
Obesity- Obese children are 3 times more likely to get eczema. Obesity results in inflammation of fat tissues that spills into other parts of the body. Excess fat also results in poor circulation and skin ailments.
Smoking- One of the leading causes, especially on the fingers that hold the cigarettes, as well as lips.
Stress- Physical or emotional stress has been known to cause enhanced sensitivity and inflammatory skin changes.
Diaper rash- In babies eczema occurs because of chemical effect of urine/faeces on sensitive skin.
Genetic influence- More likely in individuals with a family history of Eczema or other allergic conditions like Asthma, Hay fever, etc.
this ppt includes Minor ailments include common conditions such as dry skin, rashes, urticarial, skin trauma (cuts/scratches, scrapes, bruises), skin irritations (red, bumpy, scaly, itchy patches of skin, blisters).
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
2. SKIN
The largest organ of
the body, with a total
area of about 20
square feet.
Protects us from
microbes and the
elements
Helps regulate body
temperature &
permits the
sensations of touch,
heat, and cold.
3. Skin has 03 layers-
EPIDERMIS : Outermost layer of
skin, provides a waterproof barrier
& creates our skin tone.
DERMIS : Beneath the epidermis,
contains connective tissue, hair
follicles, and sweat glands.
HYPODERMIS : Deeper
subcutaneous tissue is made of fat
and connective tissue.
4. Common Skin Diseases
Eczema : Skin inflammation (dermatitis) causing an itchy rash.
Psoriasis : An autoimmune disease that causes raised, red, scaly patches to
appear on the skin.
Pruritus : severe itching of the skin, as a symptom of various ailments.
5. Athlete’s foot (tinea pedis) : Contagious fungal infection that affects the skin on
the feet and can spread to the toenails and sometimes the hands.
Jock itch (tinea cruris) : A fungal infection of the skin on the groin, upper inner
thighs, or buttocks.
Ringworm (tinea corporis) : A common and highly infectious skin infection that
causes a ring-like red rash on the skin.
Common Skin Diseases
8. Product Summary
COMPOSITION :
Derson Ointment (15 gm) = Betamethasone Valerate USP 0.1%
Derson-CL Ointment (10 gm) = Betamethasone Valerate USP 0.1% & Clotrimazole BP 1%
DESCRIPTION:
Betamethasone is a potent topical corticosteroid with anti-inflammatory & antipruritic
actions.
Clotrimazole is a broad-spectrum antifungal agent.
9. INDICATION :
Derson Ointment (15 gm)
Used to treat a variety of inflammatory, allergic or itchy skin disorders (such as – eczema, psoriasis,
pruritus, lichen simplex, lichen planus etc.) that have not responded to milder steroids or when
milder corticosteroids have not been effective. The formulation is specially suitable for dry and
scaly skin lesions.
Derson-CL Ointment (10 gm)
For the topical treatment of inflammatory dermal infections such as-
• Athlete’s foot (tinea pedis),
• Jock itch (tinea cruris)
• Ringworm (tinea corporis) and
• Candidial skin infection, etc.
Product Summary
10. Competitor Brand & Target Doctor’s
Competitor Brand
Sl. Derson Ointment Derson-CL Ointment
01. Betnovate Oint./Cream GSK Betnovate-CL Oint./Cream GSK
02. Diprobet Oint./Cream Square Oni Cream Square
03. Betson Oint./Cream Opsonin Betson-CL Oint./Cream Opsonin
04. Betaderm Oint. Incepta Betavate-CL Drug. Int.
05. Betaval Oint./Cream Healthcare Fungin-B Ibn Sina
Target Doctor’s : All Dermatologist ; Medicine Specialist ; Potential GP & RMP’s