Topical corticosteroids and their uses , applications , contraindications.pptx
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Corticosteroids can be divided into 7 classes based on potency. Topical corticosteroids are used to treat inflammatory skin conditions and their potency depends on the condition. Potential local side effects include atrophy, acneiform reactions, and infections. Systemic side effects may include HPA axis suppression, diabetes, and growth retardation in children. Intralesional steroid injections bypass the skin barrier for better delivery and less atrophy. Conditions treated include alopecia areata, keloids, and resistant psoriasis.
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This document provides information about group members studying psoriasis and summarizes key points about the disease. It discusses the etiology, pathogenesis, clinical manifestations, types, diagnosis and first-line and second-line treatment options for psoriasis. Psoriasis is characterized by thickened, scaly skin plaques and is caused by an immune system problem involving T cells. Common types include plaque, guttate and pustular psoriasis. Treatment involves topical corticosteroids, vitamin D analogs and systemic drugs like methotrexate, cyclosporine and biologics that target T cells and inflammation.
Topical agents
This document summarizes topical treatments for dermatological conditions. It discusses the principles of topical therapy, including how vehicles like creams and ointments affect drug penetration. Common topical agents are then described, such as corticosteroids which are classified based on potency. Other agents covered include emollients, retinoids, vitamin D derivatives, and calcineurin inhibitors. Specific drugs are mentioned for conditions like psoriasis, eczema, and acne. Side effects and guidelines for application are provided.
Skin care medical
This document provides information about topical skin care treatments. It discusses how topical medications can achieve a high concentration of drugs in the skin while exposing other organs minimally. It describes the process of percutaneous drug delivery and absorption through the skin. It also outlines different types of topical formulations like powders, ointments, emulsions, gels and their characteristics and use for various skin conditions. It provides details about topical anti-infectives like antifungals and antivirals. It explains PUVA therapy, how it works to treat severe skin diseases using psoralens and UVA light, and its advantages and potential side effects.
Transdermal drug delivery systems
This document discusses transdermal drug delivery systems (TDDS). TDDS deliver drugs through the skin at a controlled rate. Key points:
1. TDDS have advantages like delivering drugs over an extended period with less fluctuations compared to oral dosing. However, only small lipophilic drugs can currently be delivered.
2. The skin is the rate-limiting barrier, with the stratum corneum restricting drug entry and exit. Drugs must penetrate this layer to be absorbed systemically.
3. Factors like skin conditions, age, temperature, and drug properties affect transdermal permeation. Ideal TDDS components include potent drugs, polymers to control release, permeation enhancers,
Momef.pptx m
Mometasone furoate 0.1% w/w cream is used to treat plaque psoriasis, atopic eczema, allergic dermatitis, and seborrheic dermatitis. It works by inhibiting inflammatory mediators like prostaglandins and reducing swelling, itching, and redness. Mometasone furoate has minimal systemic absorption and is generally well-tolerated, though long term use or use on sensitive areas can cause skin thinning and irritation in some patients. It should be used with caution in pediatric patients, pregnant/nursing women, and those with viral skin infections or rosacea.
TDDS
The document summarizes a new transdermal delivery system containing sumatriptan that is being developed. Due to production problems with sumatriptan tablets, the company is switching to sumatriptan capsules and developing the new transdermal system. As the new section head, the reader is responsible for ensuring the two new products meet standards of safety, quality and efficacy.
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PowerPoint_merge.ppt.pptx
Corticosteroids can be divided into 7 classes based on potency. Topical corticosteroids are used to treat inflammatory skin conditions and their potency depends on the condition. Potential local side effects include atrophy, acneiform reactions, and infections. Systemic side effects may include HPA axis suppression, diabetes, and growth retardation in children. Intralesional steroid injections bypass the skin barrier for better delivery and less atrophy. Conditions treated include alopecia areata, keloids, and resistant psoriasis.
GROUP NO 3 PPT.pptx
This document provides information about group members studying psoriasis and summarizes key points about the disease. It discusses the etiology, pathogenesis, clinical manifestations, types, diagnosis and first-line and second-line treatment options for psoriasis. Psoriasis is characterized by thickened, scaly skin plaques and is caused by an immune system problem involving T cells. Common types include plaque, guttate and pustular psoriasis. Treatment involves topical corticosteroids, vitamin D analogs and systemic drugs like methotrexate, cyclosporine and biologics that target T cells and inflammation.
Topical agents
This document summarizes topical treatments for dermatological conditions. It discusses the principles of topical therapy, including how vehicles like creams and ointments affect drug penetration. Common topical agents are then described, such as corticosteroids which are classified based on potency. Other agents covered include emollients, retinoids, vitamin D derivatives, and calcineurin inhibitors. Specific drugs are mentioned for conditions like psoriasis, eczema, and acne. Side effects and guidelines for application are provided.
Skin care medical
This document provides information about topical skin care treatments. It discusses how topical medications can achieve a high concentration of drugs in the skin while exposing other organs minimally. It describes the process of percutaneous drug delivery and absorption through the skin. It also outlines different types of topical formulations like powders, ointments, emulsions, gels and their characteristics and use for various skin conditions. It provides details about topical anti-infectives like antifungals and antivirals. It explains PUVA therapy, how it works to treat severe skin diseases using psoralens and UVA light, and its advantages and potential side effects.
Transdermal drug delivery systems
This document discusses transdermal drug delivery systems (TDDS). TDDS deliver drugs through the skin at a controlled rate. Key points:
1. TDDS have advantages like delivering drugs over an extended period with less fluctuations compared to oral dosing. However, only small lipophilic drugs can currently be delivered.
2. The skin is the rate-limiting barrier, with the stratum corneum restricting drug entry and exit. Drugs must penetrate this layer to be absorbed systemically.
3. Factors like skin conditions, age, temperature, and drug properties affect transdermal permeation. Ideal TDDS components include potent drugs, polymers to control release, permeation enhancers,
Momef.pptx m
Mometasone furoate 0.1% w/w cream is used to treat plaque psoriasis, atopic eczema, allergic dermatitis, and seborrheic dermatitis. It works by inhibiting inflammatory mediators like prostaglandins and reducing swelling, itching, and redness. Mometasone furoate has minimal systemic absorption and is generally well-tolerated, though long term use or use on sensitive areas can cause skin thinning and irritation in some patients. It should be used with caution in pediatric patients, pregnant/nursing women, and those with viral skin infections or rosacea.
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The document summarizes a new transdermal delivery system containing sumatriptan that is being developed. Due to production problems with sumatriptan tablets, the company is switching to sumatriptan capsules and developing the new transdermal system. As the new section head, the reader is responsible for ensuring the two new products meet standards of safety, quality and efficacy.
Psoriasis part2
This document discusses various treatment options for psoriasis, including topical therapies. It provides details on topical vitamin D analogues like calcipotriene, which are first-line treatments and have efficacy without reduced effects from long-term use. Topical corticosteroids are also discussed as first-line options for mild cases, though they carry risks of tachyphylaxis and rebound with prolonged use. Other topical treatments covered include anthralin, retinoids, salicylic acid, coal tar, and calcineurin inhibitors.
Transdermal Drug Delivery system by Muskan
This document discusses transdermal drug delivery systems (TDDS). It covers the advantages like avoidance of first-pass metabolism and ease of termination of drug action. Limitations include skin irritation and limited permeability. The structure of skin and components of transdermal patches are described. Penetration enhancers and the classification of TDDS into membrane permeation-controlled, matrix diffusion-controlled, adhesive diffusion/dispersion controlled, and micro reservoir dissolution-controlled systems are summarized. Suitable drug candidates and enhancement of skin permeability are also outlined.
Trasndermal Drug Delivery System
This document discusses transdermal drug delivery systems. It provides information on:
1. Transdermal drug delivery involves administering therapeutic agents through intact skin for systemic effects. Only a small number of drug products are currently available via this route.
2. The first transdermal patch was approved in 1981 to prevent nausea and vomiting from motion sickness. By 2003, the FDA had approved over 20 transdermal patch products containing 13 different drug molecules.
3. Successful transdermal delivery depends on a drug's physicochemical properties like molecular size and polarity. The skin provides a selective penetration barrier primarily through the epidermis.
psoriasis pdf n.docx
Psoriasis is a chronic skin condition that causes patches of thick, red skin and silvery scales, most commonly occurring on the elbows, knees, scalp, lower back, face and nails. It is caused by a combination of genetic and environmental factors that lead to an overactive immune response and rapid skin cell growth. Treatment involves topical corticosteroids, vitamin D analogues, coal tar, retinoids and phototherapy with ultraviolet light to help control skin cell growth and reduce inflammation and scaling.
Drugs used in skin disorders- Mr. Panneh
This document discusses drugs used to treat various skin disorders. It begins by defining common skin lesions and conditions like macules, papules, and eczema. It then describes several categories of drugs used to treat skin disorders, including topical preparations, antihistamines for pruritus, corticosteroids for inflammation, antifungals for mycosis, and antibiotics for acne. Specific drugs are provided as examples for each category. Common drug treatments are outlined for conditions like warts, minor cuts, and fungal infections affecting different body sites. The document concludes by listing several references.
Semisolids
This document provides information about semisolid dosage forms such as ointments, pastes, creams, and gels. It defines these terms and discusses the anatomy of skin, factors affecting drug penetration through skin, and formulation and evaluation of semisolid dosage forms. The document covers the stratum corneum as the major barrier to drug penetration, routes of penetration, and biological and physicochemical factors influencing penetration. It also describes various ointment bases including oleaginous, absorption, emulsion, and water soluble bases and provides examples of each.
Semisolid dosage forms
This document provides an overview of semisolid dosage forms such as ointments, pastes, creams, and gels. It discusses the anatomy of the skin, factors that influence drug penetration through the skin, and formulation and evaluation of semisolid dosage forms. The skin consists of the epidermis, dermis and hypodermis layers. Drugs can penetrate the skin through the transepidermal, transappendageal and epidermal routes. Biological factors like skin condition and age and physicochemical factors like the drug, vehicle and their interactions influence skin penetration. Ointments are semisolid preparations meant for external application and are classified based on penetration depth and therapeutic use.
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The document discusses the structure and function of human skin and its microflora. It describes the two main ecological areas on the skin dominated by different bacterial species. The resident skin microflora is usually non-pathogenic and provides benefits like preventing pathogenic colonization. Topical preparations can target different skin layers, from the surface to the systemic circulation. Common topical dosage forms include liquids, solids, and semi-solids like lotions, creams, ointments, gels and pastes. Key considerations in formulation include viscosity and ease of application.
SEMI-SOLID DOSAGE FORM
Introduction, structure of skin, mechanism & penetration of drug through skin, ointments, cream, paste, gels, evaluation test for semisolid
Seminar principles of topical therapy
topical therapy, factors that affect absorption, frequency of applicatoin, preparations, creams, ointments, lotions, gels
Transdermal Drug Delivery System
This document provides an overview of transdermal drug delivery systems (TDDS). It discusses key topics such as the structure of the skin and its role in percutaneous absorption, penetration enhancers that increase drug absorption, common TDDS types (single layer, multi-layer, reservoir, and matrix systems), criteria for drugs suitable for TDDS, advantages and disadvantages of TDDS, basic TDDS components, and methods for evaluating and ensuring TDDS stability. The document serves as an introduction to TDDS for students.
Topical corticosteroids
This document discusses topical corticosteroids (TCS). It begins by describing the discovery and structure of corticosteroids. It then covers the pharmacokinetics of TCS, noting they are distributed in the skin and absorbed systemically before being metabolized in the liver. The potency of a TCS preparation depends on its structure, vehicle, and skin condition. The document outlines the anti-inflammatory, antiproliferative, and atrophogenic mechanisms of action of TCS. It concludes by listing common indications and side effects of TCS.
Transdermal drug delivery system
This document provides an overview of transdermal drug delivery systems. Key points include:
- Transdermal drug delivery administers therapeutic agents through the skin for systemic effects. Only a small number of drug products are available via this route.
- The first transdermal patch was approved in 1981. By 2003, the FDA had approved over 20 transdermal patch products delivering 13 drug molecules.
- Advantages of transdermal delivery include avoiding first-pass hepatic metabolism, maintaining constant blood levels, reducing dosing, and increasing compliance. Challenges include limiting the types of drugs that can be delivered and achieving high blood or plasma levels.
Psoriasis
Psoriasis is a chronic, inflammatory skin condition characterized by thickened patches of red skin covered by silvery scales. It occurs when the immune system causes skin cells to grow too quickly. The document defines psoriasis and describes the main types, risk factors, diagnosis, and treatment options including topical therapies, phototherapy, and systemic medications that target the immune system. Treatment aims to reduce inflammation and scaling based on the severity and location of symptoms.
Topical route_Dr. Mansij Biswas
This document discusses topical routes of drug administration and dosage forms. It defines topical administration as applying a drug formulation to the skin or mucous membranes to treat local disorders. There are two types - external applications spread on the skin, and internal applications to body openings. Dosage forms include solids, liquids, and semi-solids like ointments, creams, gels, and lotions. Factors like drug properties and vehicle composition affect skin absorption rates. Topical formulations provide localized treatment while avoiding first-pass metabolism and other issues of oral medications.
topical therapy in dermatology
This document provides information on topical drug delivery and formulations. It defines a topical medication as one applied to the skin or mucous membranes, allowing high drug concentration locally with minimal systemic exposure. Topical absorption is influenced by stratum corneum thickness and is highest in mucous membranes and lowest in skin areas like the soles and dorsa of hands/feet. Proper dosing of a topical medication considers factors like concentration, application frequency, site, and occlusion. Occlusion can increase drug delivery by 10-100 times by hydrating the skin. The document then discusses various topical formulations like solutions, suspensions, emulsions, gels, ointments, creams, powders and their characteristics.
Psoriasis
Psoriasis is a chronic skin disease that causes thick, red patches covered with silvery scales, most often occurring on the elbows, knees, scalp, lower back, and face. It results from the rapid buildup of skin cells. Treatment includes topical corticosteroids, vitamin D analogues, phototherapy, and systemic drugs like methotrexate. Nursing care focuses on skin care, managing symptoms, health education, and addressing psychological impacts on self-concept and quality of life.
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Side effects of steroids include both local and systemic effects. Local side effects involve changes to the skin like atrophy, easy bruising, acneiform reactions, hypertrichosis, and pigmentary changes. Prolonged use can also worsen or disguise cutaneous infections. Systemic side effects involve suppression of the HPA axis, metabolic changes like hyperglycemia, and iatrogenic Cushing's syndrome. Intralesional steroid injections provide direct delivery of steroids to lesions while reducing risk of epidermal atrophy compared to topical steroids. Conditions commonly treated with intralesional steroids include alopecia areata, keloids, hypertrophic scars, and resistant plaque
Discover the Perfect Way to Relax - Malayali Kerala Spa Ajman
Malayali Kerala Spa in Ajman, one among the top rated massage centre in ajman, welcomes you to experience high quality massage services from massage staffs from all ove rthe world! Being the best spa massage service providers, we take pride in offering traditional massage services of different countries, like
Indian Massage, Kerala Massage, Thai Massage, Pakistani Massage, Russian Massage etc
If you are seeking relaxation, pain relief, or wellness experience, our ajman spa is here for your unique needs and concerns. The services of our experienced therapists, and personalized attention will ensure that each visit will be memorable for you.
Book your appointment today and let us take you to a world of serenity and self-care. Because you deserves the best.
Health Tech Market Intelligence Prelim Questions -
The Ultimate Guide to Setting up Market Research in Health Tech part -1
How to effectively start market research in the health tech industry by defining objectives, crafting problem statements, selecting methods, identifying data collection sources, and setting clear timelines. This guide covers all the preliminary steps needed to lay a strong foundation for your research.
This lays foundation of scoping research project what are the
Before embarking on a research project, especially one aimed at scoping and defining parameters like the one described for health tech IT, several crucial considerations should be addressed. Here’s a comprehensive guide covering key aspects to ensure a well-structured and successful research initiative:
1. Define Research Objectives and Scope
Clear Objectives: Define specific goals such as understanding market needs, identifying new opportunities, assessing risks, or refining pricing strategies.
Scope Definition: Clearly outline the boundaries of the research in terms of geographical focus, target demographics (e.g., age, socio-economic status), and industry sectors (e.g., healthcare IT).
3. Review Existing Literature and Resources
Literature Review: Conduct a thorough review of existing research, market reports, and relevant literature to build foundational knowledge.
Gap Analysis: Identify gaps in existing knowledge or areas where further exploration is needed.
4. Select Research Methodology and Tools
Methodological Approach: Choose appropriate research methods such as surveys, interviews, focus groups, or data analytics.
Tools and Resources: Select tools like Google Forms for surveys, analytics platforms (e.g., SimilarWeb, Statista), and expert consultations.
5. Ethical Considerations and Compliance
Ethical Approval: Ensure compliance with ethical guidelines for research involving human subjects.
Data Privacy: Implement measures to protect participant confidentiality and adhere to data protection regulations (e.g., GDPR, HIPAA).
6. Budget and Resource Allocation
Resource Planning: Allocate resources including time, budget, and personnel required for each phase of the research.
Contingency Planning: Anticipate and plan for unforeseen challenges or adjustments to the research plan.
7. Develop Research Instruments
Survey Design: Create well-structured surveys using tools like Google Forms to gather quantitative data.
Interview and Focus Group Guides: Prepare detailed scripts and discussion points for qualitative data collection.
8. Sampling Strategy
Sampling Design: Define the sampling frame, size, and method (e.g., random sampling, stratified sampling) to ensure representation of target demographics.
Participant Recruitment: Plan recruitment strategies to reach and engage the intended participant groups effectively.
9. Data Collection and Analysis Plan
Data Collection: Implement methods for data gathering, ensuring consistency and validity.
Analysis Techniques: Decide on analytical approaches (e.g., statistical
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This document discusses various treatment options for psoriasis, including topical therapies. It provides details on topical vitamin D analogues like calcipotriene, which are first-line treatments and have efficacy without reduced effects from long-term use. Topical corticosteroids are also discussed as first-line options for mild cases, though they carry risks of tachyphylaxis and rebound with prolonged use. Other topical treatments covered include anthralin, retinoids, salicylic acid, coal tar, and calcineurin inhibitors.
Transdermal Drug Delivery system by Muskan
This document discusses transdermal drug delivery systems (TDDS). It covers the advantages like avoidance of first-pass metabolism and ease of termination of drug action. Limitations include skin irritation and limited permeability. The structure of skin and components of transdermal patches are described. Penetration enhancers and the classification of TDDS into membrane permeation-controlled, matrix diffusion-controlled, adhesive diffusion/dispersion controlled, and micro reservoir dissolution-controlled systems are summarized. Suitable drug candidates and enhancement of skin permeability are also outlined.
Trasndermal Drug Delivery System
This document discusses transdermal drug delivery systems. It provides information on:
1. Transdermal drug delivery involves administering therapeutic agents through intact skin for systemic effects. Only a small number of drug products are currently available via this route.
2. The first transdermal patch was approved in 1981 to prevent nausea and vomiting from motion sickness. By 2003, the FDA had approved over 20 transdermal patch products containing 13 different drug molecules.
3. Successful transdermal delivery depends on a drug's physicochemical properties like molecular size and polarity. The skin provides a selective penetration barrier primarily through the epidermis.
psoriasis pdf n.docx
Psoriasis is a chronic skin condition that causes patches of thick, red skin and silvery scales, most commonly occurring on the elbows, knees, scalp, lower back, face and nails. It is caused by a combination of genetic and environmental factors that lead to an overactive immune response and rapid skin cell growth. Treatment involves topical corticosteroids, vitamin D analogues, coal tar, retinoids and phototherapy with ultraviolet light to help control skin cell growth and reduce inflammation and scaling.
Drugs used in skin disorders- Mr. Panneh
This document discusses drugs used to treat various skin disorders. It begins by defining common skin lesions and conditions like macules, papules, and eczema. It then describes several categories of drugs used to treat skin disorders, including topical preparations, antihistamines for pruritus, corticosteroids for inflammation, antifungals for mycosis, and antibiotics for acne. Specific drugs are provided as examples for each category. Common drug treatments are outlined for conditions like warts, minor cuts, and fungal infections affecting different body sites. The document concludes by listing several references.
Semisolids
This document provides information about semisolid dosage forms such as ointments, pastes, creams, and gels. It defines these terms and discusses the anatomy of skin, factors affecting drug penetration through skin, and formulation and evaluation of semisolid dosage forms. The document covers the stratum corneum as the major barrier to drug penetration, routes of penetration, and biological and physicochemical factors influencing penetration. It also describes various ointment bases including oleaginous, absorption, emulsion, and water soluble bases and provides examples of each.
Semisolid dosage forms
This document provides an overview of semisolid dosage forms such as ointments, pastes, creams, and gels. It discusses the anatomy of the skin, factors that influence drug penetration through the skin, and formulation and evaluation of semisolid dosage forms. The skin consists of the epidermis, dermis and hypodermis layers. Drugs can penetrate the skin through the transepidermal, transappendageal and epidermal routes. Biological factors like skin condition and age and physicochemical factors like the drug, vehicle and their interactions influence skin penetration. Ointments are semisolid preparations meant for external application and are classified based on penetration depth and therapeutic use.
lecture 2.ppt
The document discusses the structure and function of human skin and its microflora. It describes the two main ecological areas on the skin dominated by different bacterial species. The resident skin microflora is usually non-pathogenic and provides benefits like preventing pathogenic colonization. Topical preparations can target different skin layers, from the surface to the systemic circulation. Common topical dosage forms include liquids, solids, and semi-solids like lotions, creams, ointments, gels and pastes. Key considerations in formulation include viscosity and ease of application.
SEMI-SOLID DOSAGE FORM
Introduction, structure of skin, mechanism & penetration of drug through skin, ointments, cream, paste, gels, evaluation test for semisolid
Seminar principles of topical therapy
topical therapy, factors that affect absorption, frequency of applicatoin, preparations, creams, ointments, lotions, gels
Transdermal Drug Delivery System
This document provides an overview of transdermal drug delivery systems (TDDS). It discusses key topics such as the structure of the skin and its role in percutaneous absorption, penetration enhancers that increase drug absorption, common TDDS types (single layer, multi-layer, reservoir, and matrix systems), criteria for drugs suitable for TDDS, advantages and disadvantages of TDDS, basic TDDS components, and methods for evaluating and ensuring TDDS stability. The document serves as an introduction to TDDS for students.
Topical corticosteroids
This document discusses topical corticosteroids (TCS). It begins by describing the discovery and structure of corticosteroids. It then covers the pharmacokinetics of TCS, noting they are distributed in the skin and absorbed systemically before being metabolized in the liver. The potency of a TCS preparation depends on its structure, vehicle, and skin condition. The document outlines the anti-inflammatory, antiproliferative, and atrophogenic mechanisms of action of TCS. It concludes by listing common indications and side effects of TCS.
Transdermal drug delivery system
This document provides an overview of transdermal drug delivery systems. Key points include:
- Transdermal drug delivery administers therapeutic agents through the skin for systemic effects. Only a small number of drug products are available via this route.
- The first transdermal patch was approved in 1981. By 2003, the FDA had approved over 20 transdermal patch products delivering 13 drug molecules.
- Advantages of transdermal delivery include avoiding first-pass hepatic metabolism, maintaining constant blood levels, reducing dosing, and increasing compliance. Challenges include limiting the types of drugs that can be delivered and achieving high blood or plasma levels.
Psoriasis
Psoriasis is a chronic, inflammatory skin condition characterized by thickened patches of red skin covered by silvery scales. It occurs when the immune system causes skin cells to grow too quickly. The document defines psoriasis and describes the main types, risk factors, diagnosis, and treatment options including topical therapies, phototherapy, and systemic medications that target the immune system. Treatment aims to reduce inflammation and scaling based on the severity and location of symptoms.
Topical route_Dr. Mansij Biswas
This document discusses topical routes of drug administration and dosage forms. It defines topical administration as applying a drug formulation to the skin or mucous membranes to treat local disorders. There are two types - external applications spread on the skin, and internal applications to body openings. Dosage forms include solids, liquids, and semi-solids like ointments, creams, gels, and lotions. Factors like drug properties and vehicle composition affect skin absorption rates. Topical formulations provide localized treatment while avoiding first-pass metabolism and other issues of oral medications.
topical therapy in dermatology
This document provides information on topical drug delivery and formulations. It defines a topical medication as one applied to the skin or mucous membranes, allowing high drug concentration locally with minimal systemic exposure. Topical absorption is influenced by stratum corneum thickness and is highest in mucous membranes and lowest in skin areas like the soles and dorsa of hands/feet. Proper dosing of a topical medication considers factors like concentration, application frequency, site, and occlusion. Occlusion can increase drug delivery by 10-100 times by hydrating the skin. The document then discusses various topical formulations like solutions, suspensions, emulsions, gels, ointments, creams, powders and their characteristics.
Psoriasis
Psoriasis is a chronic skin disease that causes thick, red patches covered with silvery scales, most often occurring on the elbows, knees, scalp, lower back, and face. It results from the rapid buildup of skin cells. Treatment includes topical corticosteroids, vitamin D analogues, phototherapy, and systemic drugs like methotrexate. Nursing care focuses on skin care, managing symptoms, health education, and addressing psychological impacts on self-concept and quality of life.
Combination gel of DICLOFENAC, METHYL SALICYLATE, LINSEED OIL AND MENTHOL
Indication of topical pain relief gel consisting DICLOFENAC, METHYL SALICYLATE, LINSEED OIL AND MENTHOL AS KEY INGREDIENTS
derma.pptx
Side effects of steroids include both local and systemic effects. Local side effects involve changes to the skin like atrophy, easy bruising, acneiform reactions, hypertrichosis, and pigmentary changes. Prolonged use can also worsen or disguise cutaneous infections. Systemic side effects involve suppression of the HPA axis, metabolic changes like hyperglycemia, and iatrogenic Cushing's syndrome. Intralesional steroid injections provide direct delivery of steroids to lesions while reducing risk of epidermal atrophy compared to topical steroids. Conditions commonly treated with intralesional steroids include alopecia areata, keloids, hypertrophic scars, and resistant plaque
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Discover the Perfect Way to Relax - Malayali Kerala Spa Ajman
Malayali Kerala Spa in Ajman, one among the top rated massage centre in ajman, welcomes you to experience high quality massage services from massage staffs from all ove rthe world! Being the best spa massage service providers, we take pride in offering traditional massage services of different countries, like
Indian Massage, Kerala Massage, Thai Massage, Pakistani Massage, Russian Massage etc
If you are seeking relaxation, pain relief, or wellness experience, our ajman spa is here for your unique needs and concerns. The services of our experienced therapists, and personalized attention will ensure that each visit will be memorable for you.
Book your appointment today and let us take you to a world of serenity and self-care. Because you deserves the best.
Health Tech Market Intelligence Prelim Questions -
The Ultimate Guide to Setting up Market Research in Health Tech part -1
How to effectively start market research in the health tech industry by defining objectives, crafting problem statements, selecting methods, identifying data collection sources, and setting clear timelines. This guide covers all the preliminary steps needed to lay a strong foundation for your research.
This lays foundation of scoping research project what are the
Before embarking on a research project, especially one aimed at scoping and defining parameters like the one described for health tech IT, several crucial considerations should be addressed. Here’s a comprehensive guide covering key aspects to ensure a well-structured and successful research initiative:
1. Define Research Objectives and Scope
Clear Objectives: Define specific goals such as understanding market needs, identifying new opportunities, assessing risks, or refining pricing strategies.
Scope Definition: Clearly outline the boundaries of the research in terms of geographical focus, target demographics (e.g., age, socio-economic status), and industry sectors (e.g., healthcare IT).
3. Review Existing Literature and Resources
Literature Review: Conduct a thorough review of existing research, market reports, and relevant literature to build foundational knowledge.
Gap Analysis: Identify gaps in existing knowledge or areas where further exploration is needed.
4. Select Research Methodology and Tools
Methodological Approach: Choose appropriate research methods such as surveys, interviews, focus groups, or data analytics.
Tools and Resources: Select tools like Google Forms for surveys, analytics platforms (e.g., SimilarWeb, Statista), and expert consultations.
5. Ethical Considerations and Compliance
Ethical Approval: Ensure compliance with ethical guidelines for research involving human subjects.
Data Privacy: Implement measures to protect participant confidentiality and adhere to data protection regulations (e.g., GDPR, HIPAA).
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Contingency Planning: Anticipate and plan for unforeseen challenges or adjustments to the research plan.
7. Develop Research Instruments
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Interview and Focus Group Guides: Prepare detailed scripts and discussion points for qualitative data collection.
8. Sampling Strategy
Sampling Design: Define the sampling frame, size, and method (e.g., random sampling, stratified sampling) to ensure representation of target demographics.
Participant Recruitment: Plan recruitment strategies to reach and engage the intended participant groups effectively.
9. Data Collection and Analysis Plan
Data Collection: Implement methods for data gathering, ensuring consistency and validity.
Analysis Techniques: Decide on analytical approaches (e.g., statistical
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The Ultimate Guide in Setting Up Market Research System in Health-Tech
How to effectively start market research in the health tech industry by defining objectives, crafting problem statements, selecting methods, identifying data collection sources, and setting clear timelines. This guide covers all the preliminary steps needed to lay a strong foundation for your research.
"Market Research it too text-booky, I am in the market for a decade, I am living research book" this is what the founder I met on the event claimed, few of my colleagues rolled their eyes. Its true that one cannot over look the real life experience, but one cannot out beat structured gold mine of market research.
Many 0 to 1 startup founders often overlook market research, but this critical step can make or break a venture, especially in health tech.
But Why do they skip it?
Limited resources—time, money, and manpower—are common culprits.
"In fact, a survey by CB Insights found that 42% of startups fail due to no market need, which is like building a spaceship to Mars only to realise you forgot the fuel."
Sudharsan Srinivasan
Operational Partner Pitchworks VC Studio
Overconfidence in their product’s success leads founders to assume it will naturally find its market, especially in health tech where patient needs, entire system issues and regulatory requirements are as complex as trying to perform brain surgery with a butter knife. Additionally, the pressure to launch quickly and the belief in their own intuition further contribute to this oversight. Yet, thorough market research in health tech could be the key to transforming a startup's vision into a life-saving reality, instead of a medical mishap waiting to happen.
Example of Market Research working
Innovaccer, founded by Abhinav Shashank in 2014, focuses on improving healthcare delivery through data-driven insights and interoperability solutions. Before launching their platform, Innovaccer conducted extensive market research to understand the challenges faced by healthcare organizations and the potential for innovation in healthcare IT.
Identifying Pain Points: Innovaccer surveyed healthcare providers to understand their difficulties with data integration, care coordination, and patient engagement. They found widespread frustration with siloed systems and inefficient workflows.
Competitive Analysis: Analyzed competitors offering similar solutions in healthcare analytics and interoperability. Identified gaps in comprehensive data aggregation, real-time analytics, and actionable insights.
Regulatory Compliance: Ensured their platform complied with HIPAA and other healthcare data privacy regulations. This compliance was crucial to gaining trust from healthcare providers wary of data security issues.
Customer Validation: Conducted pilot programs with several healthcare organizations to validate the platform's effectiveness in improving care outcomes and operational efficiency. Gathered feedback to refine features and user interface.
THE SPECIAL SENCES- Unlocking the Wonders of the Special Senses: Sight, Sound...
Title: Unlocking the Wonders of the Special Senses: Sight, Sound, Smell, Taste, and Balance
Introduction:
Welcome to our captivating SlideShare presentation on the Special Senses, where we delve into the extraordinary capabilities that allow us to perceive and interact with the world around us. Join us on a sensory journey as we explore the intricate structures and functions of sight, sound, smell, taste, and balance.
The special senses are our primary means of experiencing and interpreting the environment, each sense providing unique and vital information that shapes our perceptions and responses. These senses are facilitated by highly specialized organs and complex neural pathways, enabling us to see a vibrant sunset, hear a symphony, savor a delicious meal, detect a fragrant flower, and maintain our equilibrium.
In this presentation, we will:
Visual System (Sight): Dive into the anatomy and physiology of the eye, exploring how light is converted into electrical signals and processed by the brain to create the images we see. Understand common vision disorders and the mechanisms behind corrective measures like glasses and contact lenses.
Auditory System (Hearing): Examine the structures of the ear and the process of sound wave transduction, from the outer ear to the cochlea and auditory nerve. Learn about hearing loss, auditory processing, and the advances in hearing aid technology.
Olfactory System (Smell): Discover the olfactory receptors and pathways that enable the detection of thousands of different odors. Explore the connection between smell and memory and the impact of olfactory disorders on quality of life.
Gustatory System (Taste): Uncover the taste buds and the five basic tastes – sweet, salty, sour, bitter, and umami. Delve into the interplay between taste and smell and the factors influencing our food preferences and eating habits.
Vestibular System (Balance): Investigate the inner ear structures responsible for balance and spatial orientation. Understand how the vestibular system helps maintain posture and coordination, and explore common vestibular disorders and their effects.
Through engaging visuals, interactive diagrams, and insightful explanations, we aim to illuminate the complexities of the special senses and their profound impact on our daily lives. Whether you're a student, educator, or simply curious about how we perceive the world, this presentation will provide valuable insights into the remarkable capabilities of the human sensory system.
Join us as we unlock the wonders of the special senses and gain a deeper appreciation for the intricate mechanisms that allow us to experience the richness of our environment.
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Ensure the highest quality care for your patients with Cardiac Registry Support's cancer registry services. We support accreditation efforts and quality improvement initiatives, allowing you to benchmark performance and demonstrate adherence to best practices. Confidence starts with data. Partner with Cardiac Registry Support. For more details visit https://cardiacregistrysupport.com/cancer-registry-services/
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As Mumbai's premier kidney transplant and donation center, L H Hiranandani Hospital Powai is not just a medical facility; it's a beacon of hope where cutting-edge science meets compassionate care, transforming lives and redefining the standards of kidney health in India.
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6快递给客户（国内顺丰国外DHLUPS等快读邮寄）。头贼脑的倒也逗人喜爱日上三竿时山娃总爱窜进自家瓜棚里跟小伙伴们坐着聊天聊着聊着便忍不住往瓜田里逡巡一番抱起一只硕大的西瓜用石刀劈开抑或用拳头砸开每人抱起一大块就啃啃得满嘴满脸猴屁股般的红艳大家一个劲地指着对方吃吃地笑瓜裂得古怪奇形怪状却丝毫不影响瓜味甜丝丝的满嘴生津遍地都是瓜横七竖八的活像掷满了一地的大石块摘走二三只爷爷是断然发现不了的即便发现爷爷也不恼反而教山娃辨认孰熟孰嫩孰甜孰淡名义上是护瓜吃
FACIAL NERVE
The facial nerve, also known as cranial nerve VII, is one of the 12 cranial nerves originating from the brain. It's a mixed nerve, meaning it contains both sensory and motor fibres, and it plays a crucial role in controlling various facial muscles, as well as conveying sensory information from the taste buds on the anterior two-thirds of the tongue.
Electrocardiogram_20240614_173859_0000.pdf
Basics of Electrocardiogram
CONTENTS
●Conduction System of the Heart
●What is ECG or EKG?
●ECG Leads
●Normal waves of ECG.
●Dimensions of ECG.
● Abnormalities of ECG
CONDUCTION SYSTEM OF THE HEART
ECG:
●ECG is a graphic record of the electrical activity of the heart.
●Electrical activity precedes the mechanical activity of the heart.
●Electrical activity has two phases:
Depolarization- contraction of muscle
Repolarization- relaxation of muscle
ECG Leads:
●6 Chest leads
●6 Limb leads
1. Bipolar Limb Leads:
Lead 1- Between right arm(-ve) and left arm(+ve)
Lead 2- Between right arm(-ve) and left leg(+ve)
Lead 3- Between left arm(-ve)
and left leg(+ve)
2. Augmented unipolar Limb Leads:
AvR- Right arm
AvL- Left arm
AvF- Left leg
3.Chest Leads:
V1 : Over 4th intercostal
space near right sternal margin
V2: Over 4th intercostal space near left sternal margin
V3:In between V2 and V4
V4:Over left 5th intercostal space on the mid
clavicular line
V5:Over left 5th intercostal space on the anterior
axillary line
V6:Over left 5th intercostal space on the mid
axillary line.
Normal ECG:
Waves of ECG:
P Wave
•P Wave is a positive wave and the first wave in ECG.
•It is also called as atrial complex.
Cause: Atrial depolarisation
Duration: 0.1 sec
QRS Complex:
•QRS’ complex is also called the initial ventricular complex.
•‘Q’ wave is a small negative wave. It is continued as the tall ‘R’ wave, which is a positive wave.
‘R’ wave is followed by a small negative wave, the ‘S’ wave.
Cause:Ventricular depolarization and atrial repolarization
Duration: 0.08- 0.10 sec
T Wave:
•‘T’ wave is the final ventricular complex and is a positive wave.
Cause:Ventricular repolarization Duration: 0.2 sec
Intervals and Segments of ECG:
P-R Interval:
•‘P-R’ interval is the interval
between the onset of ‘P’wave and onset of ‘Q’ wave.
•‘P-R’ interval cause atrial depolarization and conduction of impulses through AV node.
Duration:0.18 (0.12 to 0.2) sec
Q-T Interval:
•‘Q-T’ interval is the interval between the onset of ‘Q’
wave and the end of ‘T’ wave.
•‘Q-T’ interval indicates the ventricular depolarization
and ventricular repolarization,
i.e. it signifies the
electrical activity in ventricles.
Duration:0.4-0.42sec
S-T Segment:
•‘S-T’ segment is the time interval between the end of ‘S’ wave and the onset of ‘T’ wave.
Duration: 0.08 sec
R-R Interval:
•‘R-R’ interval is the time interval between two consecutive ‘R’ waves.
•It signifies the duration of one cardiac cycle.
Duration: 0.8 sec
Dimension of ECG:
How to find heart rhytm of the heart?
Regular rhytm:
Irregular rhytm:
More than or less than 4
How to find heart rate using ECG?
If heart Rhytm is Regular :
Heart rate =
300/No.of large b/w 2 QRS complex
= 300/4
=75 beats/mins
How to find heart rate using ECG?
If heart Rhytm is irregular:
Heart rate = 10×No.of QRS complex in 6 sec 5large box = 1sec
5×6=30
10×7 = 70 Beats/min
Abnormalities of ECG:
Cardiac Arrythmias:
1.Tachycardia
Heart Rate more than 100 beats/min
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Satisfying Spa Massage Experience at Just 99 AED - Malayali Kerala Spa Ajman
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Our Spa in Ajman stands out for its effectiveness in enhancing wellness. Our therapists focus on treating the root cause of issues, providing tailored treatments for each client. We take pride in offering the most satisfying Pakistani Spa service, adjusting treatment plans based on client feedback.
For the most result-oriented Russian Spa treatment in Ajman, visit our Massage Center. Our Russian therapists are skilled in various techniques to address health concerns. Our body-to-body massage is efficient due to individualized care and high-grade massage oils.The Importance of Black Women Understanding the Chemicals in Their Personal C...
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Topical corticosteroids and their uses , applications , contraindications.pptx
- 1. TOPICAL CORTICOSTEROIDS Made by – Aarushi Sood Group – La3-201(2)
- 2. INTRODUCTION- • Topical corticosteroids are medications applied to the skin to reduce inflammation, itching, and redness associated with various dermatological conditions. They belong to a class of drugs called corticosteroids or steroids, which mimic the effects of hormones produced by the adrenal glands. These medications are available in various forms, including creams, ointments, lotions, gels, solutions, and foams. • These medications are classified based on their potency, ranging from low potency (mild) to high potency (very strong). The potency of a topical corticosteroid determines its strength and the severity of conditions it can effectively treat. • Topical corticosteroids work by penetrating the skin, binding to glucocorticoid receptors, and forming a complex that regulates gene transcription. This leads to the suppression of inflammatory genes and immune responses, resulting in reduced inflammation and symptom relief in skin conditions.
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