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SPDS
DEFINICIÓN
Péptidos
natriuréticos
Lesión cerebral
Conseciencia de la liberacion masiva …
Causa infrecuente de
hiponatremia hipoosmolar
CONSISTE:
Deshidratación y
pérdida de sodio
Estado de la volemia del paciente
SIADH
SPDS
CUASAS
0
1
0
2
0
4
0
3
Aumento de los péptidos natriuréticos que
desencadenarían una natriuresis masiva y,
como consecuencia, la pérdida neta de agua
(hipovolemia y deshidratación) y mayor pérdida
de sodio (hiponatremia).
Entidad infrecuente y no del todo bien
definida
Lesión cerebral:
Isquémica
Hemorrágica
Postraumática
Posneuroquirúrgica
Infecciosa
FISIOPATOLOGÍA
QUANILINA
Regulan el trasporte de
agua y sal en la mucosa
intestinal
PÉPTIDO NATRIURÉTIO ATRIAL
(PNA)
ATRIO CARDÍACO
Endotelina
Vasopresina
Catecolaminas
PÉPTIDO NATRIURÉTIO C
(PNA)
SISTEMA NERVIOSO
CENTRAL
Pituitaria anterior
Riñón
Endotelio vascular
CEREBRO PORCINO
Insufciencia cardiaca
Hipertrofia ventricular
PÉPTIDO NATRIURÉTIO
CEREBRAL (PNB)
UROQUANILINA
15 Y 16 AMINOÁCIDOS
Bloqueo de los canales de
sodio sensibles a amilorida
Natriuresis
Filtracion glomerular
Inhibicion de la reabsorcion
en el tubulo conterneado
distal y colector
Conbtraresta los efectos
de la HAD
Disminucionnde la
secrecion de renina y
aldosterona
INTRACELULAR
Actua en el segundo
mensajero del GMP ciclico
PÉPTIDO NATRIURÉTIO ATRIAL (PNA)
02
04
06
01
03
05
PÉPTIDO NATRIURÉTIO ATRIAL (PNA)
Natriuréticas y vasorelajantes
Distención de la auriculas ----- músculo liso
Vasodilatación HAD Secreción de sodio y orina
Renina-angiotensina II
Hipovolemia
Natriuresis
DIAGNOSTICO
TODOS LOS CAMBIOS ELECTROLITICOS OBSERVADOS EN EL
SSIHAD HAN SIDO DESCRITOS EN EL SCPS
Signos de depleción
de volumen:
 Hipotensión
 Disminución de
Turgor cutáneo
 Baja PVC
Perdida de sal
Laboratorios:
 Hemoconcent
ración
 Renina
plasmatica
 Niveles de
aldosterona
 FNA
 PVC
disminuida
SCPS
TRATAMIENTO
CORRECCION:
0.7-1-3 MEQ/L/HORA
NO MAYOR A 10 MEQ/L EN 24 HRS
CONTROL:
CADA 6 HRS X 24 HRS
CADA 12 HRS HASTA NORMALIZAR
SODIO
BALANCE HÍDRICO
SÍNTOMA
NA HIPERTÓNICA 3%
25-50 CC/ HORA
TABLETAS DE SAL 325 MG
Confususión
Disartria
Cuadriplejia
Paralisis pseudobulbar
MIELONÍSIS PONTINA CEREBRAL
OBJETIVOS:
 CORRECCIÓN DE LA VOLEMIA
 NORMALIZAR NATREMIA
TRASFUSIÓN
HTO: < 33% CON
PATOLOGIA CARDIACA
ASOCIADA
Se desarrolla: 1 semana post lesión cerebral
Resolución: espontanea 2-4 semanas o meses
Brain Infographics
Saturn
Saturn is composed of
hydrogen and helium
03
Earth
Earth is the third planet
from the Sun
01
Neptune
Neptune is the farthest
planet from the Sun
02
Planet Mercury is the
closest object to the Sun
Mercury
04
Mars
Despite being red,
Mars is a cold place
05
Jupiter
Jupiter is a gas giant
and the biggest planet
06
DIAGNOSTICO
Saturn
Saturn is composed of
hydrogen and helium
Earth
Earth is the third planet
from the Sun
Neptune
Neptune is the farthest
planet from the Sun
Mercury is the closest
object to the Sun
Mercury
0
1
0
2
0
3
0
4
Brain Infographics
Earth
Earth is the third
planet from the Sun
01
It’s the farthest
planet from the Sun
02
Mars
Despite being red,
Mars is a cold place
03
It’s the closest object
to the Sun
Mercury
04
Neptune
Brain Infographics
Earth
Earth is the third
planet from the Sun
Neptune
It’s the farthest
planet from the Sun
Mars
Despite being red,
Mars is a cold place
It’s the closest object
to the Sun
Mercury
Brain Infographics
Mercury is the
closest planet to the
Sun and the
smallest one
Jupiter is a gas
giant and the
biggest object in the
Solar System
It is the ringed planet.
It is composed of
hydrogen and helium
Despite being red,
Planet Mars is a
very cold place
Saturn
Mercury
Mars
Jupiter
Brain Infographics
01 02 03 04
Neptune Mercury
Earth Mars
Earth is the third
planet from the Sun
It’s the farthest
planet from the Sun
Despite being red,
Mars is a cold place
It’s the closest
object to the Sun
Brain Infographics
Neptune Mercury
Earth Mars
Earth is the third
planet from the Sun
It’s the farthest
planet from the Sun
Despite being red,
Mars is a cold place
It’s the closest object
to the Sun
Brain Infographics
Earth
Earth is the
third planet
from the Sun
Neptune
It’s the farthest
planet from the
Sun
Mars
Despite being
red, Mars is a
cold place
Mercury is the
closest object
to the Sun
Mercury
Brain Infographics
Mercury is the
closest planet to the
Sun and the
smallest one
Jupiter is a gas
giant and the
biggest object in the
Solar System
It is the ringed planet.
It is composed of
hydrogen and helium
Despite being red,
Planet Mars is a
very cold place
Saturn Mercury
Mars Jupiter
Brain Infographics
01
02
03
04
Saturn is composed of
hydrogen and helium
Earth is the third planet
from the Sun
Neptune is the farthest
planet from the Sun
Planet Mercury is the
closest object to the Sun
Brain Infographics
02
04
01
03
Earth
Earth is the third
planet from the Sun
It’s the farthest
planet from the Sun
Mars
Despite being red,
Mars is a cold place
It’s the closest object
to the Sun
Mercury Neptune
Brain Infographics
Mercury is the
closest planet to the
Sun and the
smallest one
Jupiter is a gas
giant and the
biggest object in the
Solar System
It is the ringed planet.
It is composed of
hydrogen and helium
Despite being red,
Planet Mars is a
very cold place
Saturn Mercury
Mars Jupiter
Brain Infographics
It’s the farthest
planet from the Sun
Mars
Despite being red,
Mars is a cold place
It’s the closest object
to the Sun
Mercury Neptune
PÉPTIDO NATRIURÉTIO ATRIAL (PNA)
Saturn
It’s composed of
hydrogen and
helium
Earth
Earth is the third
planet from the
Sun
Neptune
Neptune is the
farthest planet
from the Sun
Planet Mercury is
the closest object
to the Sun
Mercury Mars
Despite being red,
But Mars is a cold
place
Jupiter
Jupiter is a gas
giant and the
biggest planet
Brain Infographics
Saturn
Saturn is composed of
hydrogen and helium
Earth
Earth is the third planet
from the Sun
Neptune
Neptune is the farthest
planet from the Sun
Planet Mercury is the
closest object to the Sun
Mercury
Mars
Despite being red,
Mars is a cold place
Jupiter
Jupiter is a gas giant
and the biggest planet
Brain Infographics
Earth
Earth is the
third planet
from the Sun
Neptune
It’s the farthest
planet from the
Sun
Mars
Despite being
red, Mars is a
cold place
Mercury is the
closest object
to the Sun
Mercury
03
01
02
04
Brain Infographics
Earth is the third
planet from the Sun
Venus has a
beautiful name
Despite being red,
Mars is a cold place
Mercury is a small
planet
Brain Infographics
Mercury is the
closest planet to the
Sun and the
smallest one
Jupiter is a gas
giant and the
biggest object in the
Solar System
Saturn is the ringed
planet. It is composed
of hydrogen and
helium
Despite being red,
Planet Mars is a
very cold place
Saturn Mercury
Mars Jupiter
50% 90%
25% 75%
Brain Infographics
Earth
Earth is the third
planet from the Sun
It’s the farthest
planet from the Sun
Mars
Despite being red,
Mars is a cold place
It’s the closest object
to the Sun
Mercury Neptune
Brain Infographics
Saturn
It’s composed
of hydrogen
and helium
Earth
Earth is the
third planet
from the Sun
Neptune
Neptune is the
farthest planet
from the Sun
Mercury is the
closest object
to the Sun
Mercury
Mars
Despite being
red, Mars is a
cold place
Brain Infographics
Saturn
Saturn is composed of
hydrogen and helium
Earth
Earth is the third planet
from the Sun
Neptune
Neptune is the farthest
planet from the Sun
Planet Mercury is the
closest object to the Sun
Mercury
Mars
Despite being red,
Mars is a cold place
Jupiter
Jupiter is a gas giant
and the biggest planet
03
01 02
04 05 06
Brain Infographics
01 02
03 04
Planet Mercury is the
closest object to the Sun
Mercury
Mars
Despite being red,
Mars is a cold place
Earth
Earth is the third planet
from the Sun
Neptune
Neptune is the farthest
planet from the Sun
Brain Infographics
Mars
Jupiter
Saturn
03
01
02
Despite being red, Planet Mars is a
very cold place full of iron oxide dust
Planet Jupiter is a gas giant and the
biggest object in the Solar System
Saturn is the ringed planet. It is
composed of hydrogen and helium
Infographics
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SINDROME PERDEDOR DE SAL 2022.pptx

  • 2. DEFINICIÓN Péptidos natriuréticos Lesión cerebral Conseciencia de la liberacion masiva … Causa infrecuente de hiponatremia hipoosmolar CONSISTE: Deshidratación y pérdida de sodio Estado de la volemia del paciente SIADH SPDS
  • 3. CUASAS 0 1 0 2 0 4 0 3 Aumento de los péptidos natriuréticos que desencadenarían una natriuresis masiva y, como consecuencia, la pérdida neta de agua (hipovolemia y deshidratación) y mayor pérdida de sodio (hiponatremia). Entidad infrecuente y no del todo bien definida Lesión cerebral: Isquémica Hemorrágica Postraumática Posneuroquirúrgica Infecciosa
  • 4. FISIOPATOLOGÍA QUANILINA Regulan el trasporte de agua y sal en la mucosa intestinal PÉPTIDO NATRIURÉTIO ATRIAL (PNA) ATRIO CARDÍACO Endotelina Vasopresina Catecolaminas PÉPTIDO NATRIURÉTIO C (PNA) SISTEMA NERVIOSO CENTRAL Pituitaria anterior Riñón Endotelio vascular CEREBRO PORCINO Insufciencia cardiaca Hipertrofia ventricular PÉPTIDO NATRIURÉTIO CEREBRAL (PNB) UROQUANILINA 15 Y 16 AMINOÁCIDOS
  • 5. Bloqueo de los canales de sodio sensibles a amilorida Natriuresis Filtracion glomerular Inhibicion de la reabsorcion en el tubulo conterneado distal y colector Conbtraresta los efectos de la HAD Disminucionnde la secrecion de renina y aldosterona INTRACELULAR Actua en el segundo mensajero del GMP ciclico PÉPTIDO NATRIURÉTIO ATRIAL (PNA) 02 04 06 01 03 05
  • 6. PÉPTIDO NATRIURÉTIO ATRIAL (PNA) Natriuréticas y vasorelajantes Distención de la auriculas ----- músculo liso Vasodilatación HAD Secreción de sodio y orina Renina-angiotensina II Hipovolemia Natriuresis
  • 7. DIAGNOSTICO TODOS LOS CAMBIOS ELECTROLITICOS OBSERVADOS EN EL SSIHAD HAN SIDO DESCRITOS EN EL SCPS Signos de depleción de volumen:  Hipotensión  Disminución de Turgor cutáneo  Baja PVC Perdida de sal Laboratorios:  Hemoconcent ración  Renina plasmatica  Niveles de aldosterona  FNA  PVC disminuida SCPS
  • 8. TRATAMIENTO CORRECCION: 0.7-1-3 MEQ/L/HORA NO MAYOR A 10 MEQ/L EN 24 HRS CONTROL: CADA 6 HRS X 24 HRS CADA 12 HRS HASTA NORMALIZAR SODIO BALANCE HÍDRICO SÍNTOMA NA HIPERTÓNICA 3% 25-50 CC/ HORA TABLETAS DE SAL 325 MG Confususión Disartria Cuadriplejia Paralisis pseudobulbar MIELONÍSIS PONTINA CEREBRAL OBJETIVOS:  CORRECCIÓN DE LA VOLEMIA  NORMALIZAR NATREMIA TRASFUSIÓN HTO: < 33% CON PATOLOGIA CARDIACA ASOCIADA Se desarrolla: 1 semana post lesión cerebral Resolución: espontanea 2-4 semanas o meses
  • 9.
  • 10. Brain Infographics Saturn Saturn is composed of hydrogen and helium 03 Earth Earth is the third planet from the Sun 01 Neptune Neptune is the farthest planet from the Sun 02 Planet Mercury is the closest object to the Sun Mercury 04 Mars Despite being red, Mars is a cold place 05 Jupiter Jupiter is a gas giant and the biggest planet 06
  • 11. DIAGNOSTICO Saturn Saturn is composed of hydrogen and helium Earth Earth is the third planet from the Sun Neptune Neptune is the farthest planet from the Sun Mercury is the closest object to the Sun Mercury 0 1 0 2 0 3 0 4
  • 12. Brain Infographics Earth Earth is the third planet from the Sun 01 It’s the farthest planet from the Sun 02 Mars Despite being red, Mars is a cold place 03 It’s the closest object to the Sun Mercury 04 Neptune
  • 13. Brain Infographics Earth Earth is the third planet from the Sun Neptune It’s the farthest planet from the Sun Mars Despite being red, Mars is a cold place It’s the closest object to the Sun Mercury
  • 14. Brain Infographics Mercury is the closest planet to the Sun and the smallest one Jupiter is a gas giant and the biggest object in the Solar System It is the ringed planet. It is composed of hydrogen and helium Despite being red, Planet Mars is a very cold place Saturn Mercury Mars Jupiter
  • 15. Brain Infographics 01 02 03 04 Neptune Mercury Earth Mars Earth is the third planet from the Sun It’s the farthest planet from the Sun Despite being red, Mars is a cold place It’s the closest object to the Sun
  • 16. Brain Infographics Neptune Mercury Earth Mars Earth is the third planet from the Sun It’s the farthest planet from the Sun Despite being red, Mars is a cold place It’s the closest object to the Sun
  • 17. Brain Infographics Earth Earth is the third planet from the Sun Neptune It’s the farthest planet from the Sun Mars Despite being red, Mars is a cold place Mercury is the closest object to the Sun Mercury
  • 18. Brain Infographics Mercury is the closest planet to the Sun and the smallest one Jupiter is a gas giant and the biggest object in the Solar System It is the ringed planet. It is composed of hydrogen and helium Despite being red, Planet Mars is a very cold place Saturn Mercury Mars Jupiter
  • 19. Brain Infographics 01 02 03 04 Saturn is composed of hydrogen and helium Earth is the third planet from the Sun Neptune is the farthest planet from the Sun Planet Mercury is the closest object to the Sun
  • 20. Brain Infographics 02 04 01 03 Earth Earth is the third planet from the Sun It’s the farthest planet from the Sun Mars Despite being red, Mars is a cold place It’s the closest object to the Sun Mercury Neptune
  • 21. Brain Infographics Mercury is the closest planet to the Sun and the smallest one Jupiter is a gas giant and the biggest object in the Solar System It is the ringed planet. It is composed of hydrogen and helium Despite being red, Planet Mars is a very cold place Saturn Mercury Mars Jupiter
  • 22. Brain Infographics It’s the farthest planet from the Sun Mars Despite being red, Mars is a cold place It’s the closest object to the Sun Mercury Neptune
  • 23. PÉPTIDO NATRIURÉTIO ATRIAL (PNA) Saturn It’s composed of hydrogen and helium Earth Earth is the third planet from the Sun Neptune Neptune is the farthest planet from the Sun Planet Mercury is the closest object to the Sun Mercury Mars Despite being red, But Mars is a cold place Jupiter Jupiter is a gas giant and the biggest planet
  • 24. Brain Infographics Saturn Saturn is composed of hydrogen and helium Earth Earth is the third planet from the Sun Neptune Neptune is the farthest planet from the Sun Planet Mercury is the closest object to the Sun Mercury Mars Despite being red, Mars is a cold place Jupiter Jupiter is a gas giant and the biggest planet
  • 25. Brain Infographics Earth Earth is the third planet from the Sun Neptune It’s the farthest planet from the Sun Mars Despite being red, Mars is a cold place Mercury is the closest object to the Sun Mercury
  • 26. 03 01 02 04 Brain Infographics Earth is the third planet from the Sun Venus has a beautiful name Despite being red, Mars is a cold place Mercury is a small planet
  • 27. Brain Infographics Mercury is the closest planet to the Sun and the smallest one Jupiter is a gas giant and the biggest object in the Solar System Saturn is the ringed planet. It is composed of hydrogen and helium Despite being red, Planet Mars is a very cold place Saturn Mercury Mars Jupiter 50% 90% 25% 75%
  • 28. Brain Infographics Earth Earth is the third planet from the Sun It’s the farthest planet from the Sun Mars Despite being red, Mars is a cold place It’s the closest object to the Sun Mercury Neptune
  • 29. Brain Infographics Saturn It’s composed of hydrogen and helium Earth Earth is the third planet from the Sun Neptune Neptune is the farthest planet from the Sun Mercury is the closest object to the Sun Mercury Mars Despite being red, Mars is a cold place
  • 30. Brain Infographics Saturn Saturn is composed of hydrogen and helium Earth Earth is the third planet from the Sun Neptune Neptune is the farthest planet from the Sun Planet Mercury is the closest object to the Sun Mercury Mars Despite being red, Mars is a cold place Jupiter Jupiter is a gas giant and the biggest planet 03 01 02 04 05 06
  • 31. Brain Infographics 01 02 03 04 Planet Mercury is the closest object to the Sun Mercury Mars Despite being red, Mars is a cold place Earth Earth is the third planet from the Sun Neptune Neptune is the farthest planet from the Sun
  • 32. Brain Infographics Mars Jupiter Saturn 03 01 02 Despite being red, Planet Mars is a very cold place full of iron oxide dust Planet Jupiter is a gas giant and the biggest object in the Solar System Saturn is the ringed planet. It is composed of hydrogen and helium
  • 33. Infographics You can add and edit some infographics to your presentation to show your data in a visual way. ● Choose your favourite infographic and insert it in your presentation using Ctrl C + Ctrl V or Cmd C + Cmd V in Mac. ● Select one of the parts and ungroup it by right-clicking and choosing “Ungroup”. ● Change the color by clicking on the paint bucket. ● Then resize the element by clicking and dragging one of the square-shaped points of its bounding box (the cursor should look like a double-headed arrow). Remember to hold Shift while dragging to keep the proportions. ● Group the elements again by selecting them, right-clicking and choosing “Group”. ● Repeat the steps above with the other parts and when you’re done editing, copy the end result and paste it into your presentation. ● Remember to choose the “Keep source formatting” option so that it keeps the design. For more info, please visit Slidesgo School.