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SEX-LINKED
INHERITANCE
BY: MRS. PRECILLA C. STEPHEN
DEFINITION
◦ It is the inheritance of a trait(phenotype)
that is determined by a gene located on one
of the sex chromosome.
2
3
X-LINKED
DOMINANT
INHERITANCE
◦ Dominant gene is carried on the X-gene
◦ Male – get their X-chromosome from their
mother
◦ Females – get their X-chromosome from both of
their parents
◦ If the mother is a carrier of the mutated gene
◦ 50% of the son or/and daughter will be affected
◦ 50% of the son or/and daughter will be normal 4
5
6
X-LINKED
DOMINANT
INHERITANCE
◦ If the father is a carrier of the mutated
gene
◦ 100% of his daughter will have the
disorder
◦ 0% of his son will have the disorder
7
8
X-LINKED
DOMINANT
INHERITANCE
◦ If both parents are a carrier of the
mutated gene
◦ 100% of his daughter will have the
disorder
◦ 50% of his son will have the disorder
◦ 50% of his son will be unaffected or
normal 9
X-LINKED
RECESSIVE
INHERITANCE
◦ A mode of inheritance on the X-
Chromosome that causes the phenotype
to be expressed
◦ Female carriers have only copy of the
gene and usually don’t express the
phenotype.
◦ Ex: Color blindness, haemophilia 10
Y- LINKED
INHERITANCE
◦ Holandric Inheritance
◦ Y-chromosome is small and doesn’t
contain numerous genes
◦ Y-linked diseases or disorder are very
rare
◦ It occurs between fathers and his sons.
11
12
13

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Sex linked inheritance

  • 2. DEFINITION ◦ It is the inheritance of a trait(phenotype) that is determined by a gene located on one of the sex chromosome. 2
  • 3. 3
  • 4. X-LINKED DOMINANT INHERITANCE ◦ Dominant gene is carried on the X-gene ◦ Male – get their X-chromosome from their mother ◦ Females – get their X-chromosome from both of their parents ◦ If the mother is a carrier of the mutated gene ◦ 50% of the son or/and daughter will be affected ◦ 50% of the son or/and daughter will be normal 4
  • 5. 5
  • 6. 6
  • 7. X-LINKED DOMINANT INHERITANCE ◦ If the father is a carrier of the mutated gene ◦ 100% of his daughter will have the disorder ◦ 0% of his son will have the disorder 7
  • 8. 8
  • 9. X-LINKED DOMINANT INHERITANCE ◦ If both parents are a carrier of the mutated gene ◦ 100% of his daughter will have the disorder ◦ 50% of his son will have the disorder ◦ 50% of his son will be unaffected or normal 9
  • 10. X-LINKED RECESSIVE INHERITANCE ◦ A mode of inheritance on the X- Chromosome that causes the phenotype to be expressed ◦ Female carriers have only copy of the gene and usually don’t express the phenotype. ◦ Ex: Color blindness, haemophilia 10
  • 11. Y- LINKED INHERITANCE ◦ Holandric Inheritance ◦ Y-chromosome is small and doesn’t contain numerous genes ◦ Y-linked diseases or disorder are very rare ◦ It occurs between fathers and his sons. 11
  • 12. 12
  • 13. 13