The .NET Service Bus is a core part of Microsoft's .NET Services offering that aims to implement the enterprise service bus (ESB) pattern at an internet scale on Azure. It provides features like identity and access control, naming, service registry, and messaging capabilities designed to operate globally at large scale. The .NET Service Bus addresses the challenge of bidirectional communication between on-premise and cloud applications by creating secure channels between them. It also supports publish/subscribe architectures for loose coupling of services.