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Dr. Shubhanshu
Guide - Dr John Mukhopadhaya
History
Introduction
 Osteonecrosis of the femoral head (ONFH) is the
final common pathway of a series of derangements
 Decrease in blood flow
I. cellular death
II. Fracture
III. collapse of the articular surface
 in young
 60% B/L
 Spontaneous regression is rare
 Untreated patients :collapse 67% in asymptomatic
and 85% of symptomatic.
Etiology
 Idiopathic
 Genetic
 Metabolic factors
 Local factors
Anterolateral Sequestrum
Cresent Sign
Sclerosis
Cystic changes
Loss of spherical weight
bearing dome Partial collapse of head
Lytic lesion
Algorithm for the management and treatment of patients with osteonecrosis of
the femoral head. ONFH: Osteonecrosis of the femoral head; FHCD: Femoral head core
decompression; NVBG: Non vascularized bone graft; BA: Biologic agents; VBG:
Vascularized bone graft;
AIM Of Treatment
 Early intervation
 Preserve rather than replacing femoral head and
cartilage
Medical Management
 For small, asymptomatic lesion
 When surgery is contraindicated or declined
Medical Management
 Anabolic androgenic steriod
 Motomura et al found incidence of steroid induced
osteonecrosis using combination of warfarin,
probucol.
 Enoxaparin- 12wks prevent progression of stage 1 & 2
ONFN on 2 year followup
 Ilioprost- in bone marrow syndrome and ON
Medical Management
 Alendronate: Agrawala et al reported that
improvement in pain
 Bisphosphonates for pain invovement
 Pulsed Electromagnetic field stimulation
 Wang et al compared harris hip scores showed
effective result in 79% Extracorporeal shockwave
therapy and 29% non vacularised fibular graft.
 Hyperbaric oxygen: Reis et al, 13/16 patient with stage 1
appeared normal MRI after 100 days therapy
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx
Seminar on Osteonecrosis of femoral head.pptx

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Seminar on Osteonecrosis of femoral head.pptx

  • 1. Dr. Shubhanshu Guide - Dr John Mukhopadhaya
  • 3. Introduction  Osteonecrosis of the femoral head (ONFH) is the final common pathway of a series of derangements  Decrease in blood flow I. cellular death II. Fracture III. collapse of the articular surface
  • 4.  in young  60% B/L  Spontaneous regression is rare  Untreated patients :collapse 67% in asymptomatic and 85% of symptomatic.
  • 5.
  • 6.
  • 7. Etiology  Idiopathic  Genetic  Metabolic factors  Local factors
  • 8.
  • 9.
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  • 17. Cresent Sign Sclerosis Cystic changes Loss of spherical weight bearing dome Partial collapse of head Lytic lesion
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  • 28. Algorithm for the management and treatment of patients with osteonecrosis of the femoral head. ONFH: Osteonecrosis of the femoral head; FHCD: Femoral head core decompression; NVBG: Non vascularized bone graft; BA: Biologic agents; VBG: Vascularized bone graft;
  • 29. AIM Of Treatment  Early intervation  Preserve rather than replacing femoral head and cartilage
  • 30. Medical Management  For small, asymptomatic lesion  When surgery is contraindicated or declined
  • 31. Medical Management  Anabolic androgenic steriod  Motomura et al found incidence of steroid induced osteonecrosis using combination of warfarin, probucol.  Enoxaparin- 12wks prevent progression of stage 1 & 2 ONFN on 2 year followup  Ilioprost- in bone marrow syndrome and ON
  • 32. Medical Management  Alendronate: Agrawala et al reported that improvement in pain  Bisphosphonates for pain invovement  Pulsed Electromagnetic field stimulation
  • 33.  Wang et al compared harris hip scores showed effective result in 79% Extracorporeal shockwave therapy and 29% non vacularised fibular graft.  Hyperbaric oxygen: Reis et al, 13/16 patient with stage 1 appeared normal MRI after 100 days therapy