This document discusses research conducted to develop effective messaging around social determinants of health. Through focus groups and surveys of over 3,000 Americans, researchers tested various messages and identified best practices. The most persuasive message discussed how, despite U.S. leadership in healthcare, Americans do not have as long life expectancies as other countries, but framing it in a way that doesn't trigger political biases. The research showed the importance of priming audiences, offering potential solutions, incorporating personal responsibility, and focusing on shared experiences rather than specific disparities.