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Sclera and Cornea
Group members
Abenezer Bogale
Arsema Beshewa
Bamlak Cherinet
Introduction
• Both of them make up the outer covering of the
eye
• They are connective tissues containing collagen
fibrils embedded in proteoglycan rich extra-
fibrilar matrix
• Strong structures because of the deposition of
collagen in lamellar structure
• The both protect the eye from increased pressure
within and mechanical insult from outside
Cornea
• It is uniquely transparent
• The transparency is because of the coneal
collagen fibrils' arrangement in which they are
positioned in uniform diameter with respect to
eachother in a lateral fashion
• The main refractive element of the eye
• It is the part of the eye anterior to the aqueous
humor
"Cornu", Latin, horn
Cornea cont.
• No blood supply- gets metabolites by diffusion
• 5 layers
– Epithelium
– Bowman's layer
– Stroma
– Descmet's membrane
– Endothelium
Cont…
Epithelium
It is a protective layer against foreign material and
gives some mechanical support
It consist upto 10 cell layer with non stratified
squamous non kerstinized morphology
Bowmans layer
It has a dense accumulation of collagen fibrils that are
tightly interwoven
It is only 10 micrometers thick
Cont...
Stroma
It is about 800 micrometers thick
It is composed of distinct lamellae composed of
parallel arranged tightly packed and very regularly spaced
collagen fibrils
Descment membrane
It is 10 upto 20 micrometer thick
It increases during life time
It is composed of collagen type IV and glycoprotein
Cont...
Endothelium
It prevents uncontrolled entrance of foreign
substances including water
It dehydrates water from stroma through water
pumps
Sclera
It comes from Greek word hard
It is opaque and it is whitish from outside
It is covered by translucent membrane of
conjunctiva
It is 1 millimeter
Thank you

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Sclera and cornea

  • 1. Sclera and Cornea Group members Abenezer Bogale Arsema Beshewa Bamlak Cherinet
  • 2. Introduction • Both of them make up the outer covering of the eye • They are connective tissues containing collagen fibrils embedded in proteoglycan rich extra- fibrilar matrix • Strong structures because of the deposition of collagen in lamellar structure • The both protect the eye from increased pressure within and mechanical insult from outside
  • 3.
  • 4. Cornea • It is uniquely transparent • The transparency is because of the coneal collagen fibrils' arrangement in which they are positioned in uniform diameter with respect to eachother in a lateral fashion • The main refractive element of the eye • It is the part of the eye anterior to the aqueous humor "Cornu", Latin, horn
  • 5. Cornea cont. • No blood supply- gets metabolites by diffusion • 5 layers – Epithelium – Bowman's layer – Stroma – Descmet's membrane – Endothelium
  • 6. Cont… Epithelium It is a protective layer against foreign material and gives some mechanical support It consist upto 10 cell layer with non stratified squamous non kerstinized morphology Bowmans layer It has a dense accumulation of collagen fibrils that are tightly interwoven It is only 10 micrometers thick
  • 7. Cont... Stroma It is about 800 micrometers thick It is composed of distinct lamellae composed of parallel arranged tightly packed and very regularly spaced collagen fibrils Descment membrane It is 10 upto 20 micrometer thick It increases during life time It is composed of collagen type IV and glycoprotein
  • 8. Cont... Endothelium It prevents uncontrolled entrance of foreign substances including water It dehydrates water from stroma through water pumps
  • 9.
  • 10. Sclera It comes from Greek word hard It is opaque and it is whitish from outside It is covered by translucent membrane of conjunctiva It is 1 millimeter