Scabies is a skin infection caused by mites that burrow into the skin. It is transmitted through direct skin-to-skin contact with an infected person. Symptoms include an itchy rash. Diagnosis is usually made based on symptoms and history of contact with infected individuals. Treatment involves applying prescription topical creams or lotions to kill the mites. Proper treatment of all infected individuals and environmental cleaning is important to prevent outbreaks. Treatment may need to be repeated if symptoms persist or new burrows appear.