Sara- a 35-year-old Hispanic woman- visited her family physician compl.pdf
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Sara, a 35-year-old Hispanic woman, visited her family physician complaining of a persistence fever. She states that she has been feverish for the past five days. The patient state that she could not remember any feverish episodes in the past. She was diagnosed with tuberculosis as a teenager. She is currently taking any medication and occasionally drinks alcohol. He had contracted tuberculosis when he was 17 , but he had no family history of TB. Sara tells her doctor that 2 days prior to her visit, she had suddenly developed chills, a sore throat, and a fever ( 39.40 C ). Blood tests were done which showed that his white blood cell (WBC) count was elevated ( 12 , 000 U / L ) along with other tests that indicated inflammation. Rapid antigen tests for influenza and pneumococcus negative. A sputum was also collected for culture. Sara was sent home, but her fever continued to rise. She went to the ER, was admitted to the hospital, and initially diagnosed with bronchopneumonia. Intravenous antibiotics were started. On the second day after admission, the patient's temperature began to subside and the sputum smear was negative for acid-fast bacilli. In addition to the lab results shown below, the organism isolated from the sputum and blood cultures was also PYR positive. 1. What is the diagnosis of this patient? a. Sepsis due to bacterial infection b. Bacterial bronchopneumonia and bacteremia c. Upper respiratory bacterial infection d. Generalized viral infection 2. What agent do you think is causing this problem? a. Streptococcus preumoniae b. Staphylococcus aureus c. Streptococcus pyogenes d. Streptococcus agalactiae 3. Which test allows to determine (differentiate) between the possible Streptococcal species which caused Sara's infection. a. bacitracin susceptibility test b. catalase test c. gram stain d. hemolytic pattern 4. List one other disease that this organism may cause 5. What is the major virulence factor of this organism?.
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In December 2009, a 45-year-old female presented to the emergency dep.pdf
In December 2009, a 45-year-old female presented to the emergency department (ED) 2 days
following abrupt onset of sore throat, nonproductive cough, chills, and mild fever. A chest
radiograph was performed, which was normal. She was diagnosed with bronchitis and asked to
follow up with her primary care physician, who subsequently started her on levofloxacin and
albuterol. Four days later she presented again to the ED with worsening cough, dispread, fever
(38.3 degree C; 101 degree F), and generalized lethargy. Additionally, she reported new
symptoms including a global headache, dizziness, myalgias, and arthralgias. She had no
abdominal pain, but reported nausea and anorexia. Her chest radiograph showed diffuse
reticulonodular opacities throughout the left lung, which were not present on her visit 4 days
previously. The patient was admitted for further evaluation. Questioning revealed the following:
she had a history of diabetes and hypertension. she smoked an average of a pack of cigarettes
daily, and she had received the seasonal influenza vaccine. Her husband was recently ill with
cough, but no order symptoms. On day 2 of hospitalization the patient\'s respiratory rate
increased from 22 to 46 and her oxygen saturation dropped while on oxygen administered by
nasal canola. She was transferred to an intensive care unit, where her respiratory status quickly
deteriorated, necessitating emergency intubation. A new chest radiograph showed bilateral
involvement, and she was begun on vancomycin, anreonam, and azithromycin. Blood cultures
drawn on her admission were negative, and an expectorated sputum sample taken at the same
time was not processed due to poor specimen quality. A PCR test performed on a
nasopharyngeal swab was positive for a viral agent, revealing the etiology of her infection (Fig.
10.1). What is the agent causing her infection? What are the key virulence factors of this agent?
How does this virus change over time? What made this virus unique in 2009?
Solution
Answer= 1] The agent causing her infection is influenza virus
Human influenza virus can evolve rapidly by 2 mechanisms
1] antigenic shift = genetic reassortment between a human & non human virus in non human
host
2] antigenic drift = accumulation of mutations that facilitate evasion of host immune response
New influenza viruses can be constantly emeges from environment
2] influenza constantly change by 2 different ways
antigenic drift = These are small changes in genes of influenza viruses that happen continuously
over time
as the virus replicates
Antigenic shift = is an abrupt major changes resulting in hemagglutinin & neuraminidase
proteins in influenza viruses that infect humans
Such a shift occured in 2009 when H1N1 virus with a new combination of genes emerged to
infect people & quickly spread causing a pandemic
when shift happens most people has no protection against H1N1.
Answer Clinical Application Questions 1-3 for Chapter 12 on page
Answer Clinical Application Questions 1-3 for Chapter 12 on page 368 and Clinical Application Question 1-3 for Chapter 13 on page 400. Answers should be submitted in a word document with any associated references used.?
Answer Clinical Application Questions 1-3 for Chapter 12 on page 368
a) A girl developed generalized seizures. A CT scan revealed a single brain lesion consistent with a tumor. Biopsy of the session showed cysticerus. The patient lived in South Carolina and had never traveled outside the state. What parasite caused her disease? How is this disease transmitted? How might it be prevented?
b) A California farmer developed a low-grade fever, myalgia, and cough. A chest X-ray exam revealed infiltrate in the lung. Microscopic exam of the sputum revealed round budding Cells. A sputum culture grew mycelia and arthroconidia. What organism is most likely the cause of the symptom? How is this disease transmitted? How might it be prevented.
c) A teeaged male in California complained of remittent fever, chills, and headaches. A blood smear revealed ring-shaped cells in his red blood cells. He was successfully treated with primaquine and chloroquine. The patient lives near the San Luis Rey River and has no history of foreign travel, blood transfusion, or intravenous drug use. What is the disease ? How was it
acquired?
and Clinical Application Question 1-3 for Chapter 13 on page 400.
A) A 40 year old man who was seropositive for HIV experienced abdominal pain, fatique, and low grade fever (38 degree C) for 2 weeks. A chest X-ray exam revealed lung infiltrates. Gram and acid fast stains were negative. A viral culture revealed the cause of his symptoms: a large , enveloped polyhedral virus with double-stranded DNA. What is the disease? Which virus causes it? Why was virus culture done after Gram and acid-fast stain results were obtained
B) A new born female developed extensive vesicular and ulcerative ; lesions over her face and chest. What is the most likely symptoms? How would you determine the viral cause of this disease without doing a viral culture?
C) By May 14, two people living in the same household had died with five days of each other. Their illnesses were characterized by abrupt onset of fever, muscle pain, headache , and cough, followed by rapid development of respiratory failure. By the end of the year, 36 cases of the disease, with a 50% mortality rate, had been confirmed. A member of the Orthomyxoviridae, Bunyaviridac, or Adenoviridac could cause this disease . Differentiate among these families by method of transmission, morphology, nucleic acid, and type of replication. The reservoir for this disease is mice. Name the disease .
...
A 65 year old man presents to the hospital with a one week history of.docx
A 65 year old man presents to the hospital with a one week history of malaise, headache, fever, and chils. He is admitted and over the next week his disease progressed with a worsening cough and shortness of breath. His physical exam was benign except for pulmonary compromise. The patient is current on all of their vaccinations and has no recent travel history. A chest radiograph showed multilobar infiltrates. Other significant laboratory findings include an elevated white blood cell count with increased polymorphonuclear neutrophils. Because the patient had a prior history of drug abuse and akcoholism, a toxicology screen and HIV serology were performed. Both were negative. A bronchoscopy was performed, with a bronchoalveolar lavage (BAL) showing many white blood cells, but no organisms. Calcofluor white stains for fungi and direct fluorescent-antibody stain (DFA) for Pneumocystis were also negative. Routine bacterial culture of the BAL was negative. An organism was recovered only on buffered charcoal yeast extract agar. Based on this information, what is the most likely pathogen? B. pertussis Lpneumophila H. influenzae Brucella spp.
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Fever Of Unknown Origin
Contains 17 clinical situations of prolonged fever and discussion of various differential diagnosis based on them. Also gives the key points in the diagnosis of a prototype diagnosis and the usefulness of a relevant investigation modality in identifying these conditions. This power point presentaion is based on the chapter in Harrison's Text Book on Internal Medicine chapter on Fever of Unknown Origin
A 65 vear oid man presents to the hospital with a one week history of.docx
A 65 vear oid man presents to the hospital with a one week history of malaise, headache, fever, and chilis. He is admitted and over the next week his disease progressed with a worsening cough and shortness of breath. His physical exam was benign except for pulmonary compromise. The patient is current on all of their vaccinations and has no recent travel history. A chestradiograph showed multilobar infiltrates. Other sighificant laboratory findings include an elevated white blood cell count with increased polymorphonuclearneutrophils. Because the patient had a prior history of drug abuse and alcoholism, a toxicology screen and HIV serology were performed. Both were negative. A bronchoscopy was performed, with a bronchoalveolar lavage (BAL) showing many white blood cell5, but no organisms. Calcofluor white stains for fungi and direct fluorescent-antibody stain (DFA) for Pneumocystis were aiso negative. Routine bacterial culture of the BAL was negative. Question 1 1 pts Wny was the BAL routine bacterial culture negative? The pasients condtion is not due to a microorganism The pathogen is not a bacteniuin The pothosen a not present in BAL. Poutine bacteriat culfure was not surhcient to recover the puthogen Question 2 1 pts Gased on the patient shistory and condition, what teating should be pertormed next? Bit, pultive for Legionella An organism was recovered only on buffered charcoal yeast extract agar. Based on this information, what is the most likely pathogen? B. pertussis Lpneumophila H. influenzae Brucella spp: Question 4 The organism was most likely transmitted by: Handing of inimul prodicts Reipiratory droblets from an infected persen. Inhulation of water droplets An arthropod vectar lexin- tick Question 5 1 pts What other testing can be performed to detect this organism in a patient? Uinury ankgen testing Elektain testing Culuie supplementation with cystiane. Wea bienati trest
.
MCQs & Case Discussion- 2
Discussion on clinical cases of respiratory infections along with MCQs to test theoretical knowledge.
Recommended
In December 2009, a 45-year-old female presented to the emergency dep.pdf
In December 2009, a 45-year-old female presented to the emergency department (ED) 2 days
following abrupt onset of sore throat, nonproductive cough, chills, and mild fever. A chest
radiograph was performed, which was normal. She was diagnosed with bronchitis and asked to
follow up with her primary care physician, who subsequently started her on levofloxacin and
albuterol. Four days later she presented again to the ED with worsening cough, dispread, fever
(38.3 degree C; 101 degree F), and generalized lethargy. Additionally, she reported new
symptoms including a global headache, dizziness, myalgias, and arthralgias. She had no
abdominal pain, but reported nausea and anorexia. Her chest radiograph showed diffuse
reticulonodular opacities throughout the left lung, which were not present on her visit 4 days
previously. The patient was admitted for further evaluation. Questioning revealed the following:
she had a history of diabetes and hypertension. she smoked an average of a pack of cigarettes
daily, and she had received the seasonal influenza vaccine. Her husband was recently ill with
cough, but no order symptoms. On day 2 of hospitalization the patient\'s respiratory rate
increased from 22 to 46 and her oxygen saturation dropped while on oxygen administered by
nasal canola. She was transferred to an intensive care unit, where her respiratory status quickly
deteriorated, necessitating emergency intubation. A new chest radiograph showed bilateral
involvement, and she was begun on vancomycin, anreonam, and azithromycin. Blood cultures
drawn on her admission were negative, and an expectorated sputum sample taken at the same
time was not processed due to poor specimen quality. A PCR test performed on a
nasopharyngeal swab was positive for a viral agent, revealing the etiology of her infection (Fig.
10.1). What is the agent causing her infection? What are the key virulence factors of this agent?
How does this virus change over time? What made this virus unique in 2009?
Solution
Answer= 1] The agent causing her infection is influenza virus
Human influenza virus can evolve rapidly by 2 mechanisms
1] antigenic shift = genetic reassortment between a human & non human virus in non human
host
2] antigenic drift = accumulation of mutations that facilitate evasion of host immune response
New influenza viruses can be constantly emeges from environment
2] influenza constantly change by 2 different ways
antigenic drift = These are small changes in genes of influenza viruses that happen continuously
over time
as the virus replicates
Antigenic shift = is an abrupt major changes resulting in hemagglutinin & neuraminidase
proteins in influenza viruses that infect humans
Such a shift occured in 2009 when H1N1 virus with a new combination of genes emerged to
infect people & quickly spread causing a pandemic
when shift happens most people has no protection against H1N1.
Answer Clinical Application Questions 1-3 for Chapter 12 on page
Answer Clinical Application Questions 1-3 for Chapter 12 on page 368 and Clinical Application Question 1-3 for Chapter 13 on page 400. Answers should be submitted in a word document with any associated references used.?
Answer Clinical Application Questions 1-3 for Chapter 12 on page 368
a) A girl developed generalized seizures. A CT scan revealed a single brain lesion consistent with a tumor. Biopsy of the session showed cysticerus. The patient lived in South Carolina and had never traveled outside the state. What parasite caused her disease? How is this disease transmitted? How might it be prevented?
b) A California farmer developed a low-grade fever, myalgia, and cough. A chest X-ray exam revealed infiltrate in the lung. Microscopic exam of the sputum revealed round budding Cells. A sputum culture grew mycelia and arthroconidia. What organism is most likely the cause of the symptom? How is this disease transmitted? How might it be prevented.
c) A teeaged male in California complained of remittent fever, chills, and headaches. A blood smear revealed ring-shaped cells in his red blood cells. He was successfully treated with primaquine and chloroquine. The patient lives near the San Luis Rey River and has no history of foreign travel, blood transfusion, or intravenous drug use. What is the disease ? How was it
acquired?
and Clinical Application Question 1-3 for Chapter 13 on page 400.
A) A 40 year old man who was seropositive for HIV experienced abdominal pain, fatique, and low grade fever (38 degree C) for 2 weeks. A chest X-ray exam revealed lung infiltrates. Gram and acid fast stains were negative. A viral culture revealed the cause of his symptoms: a large , enveloped polyhedral virus with double-stranded DNA. What is the disease? Which virus causes it? Why was virus culture done after Gram and acid-fast stain results were obtained
B) A new born female developed extensive vesicular and ulcerative ; lesions over her face and chest. What is the most likely symptoms? How would you determine the viral cause of this disease without doing a viral culture?
C) By May 14, two people living in the same household had died with five days of each other. Their illnesses were characterized by abrupt onset of fever, muscle pain, headache , and cough, followed by rapid development of respiratory failure. By the end of the year, 36 cases of the disease, with a 50% mortality rate, had been confirmed. A member of the Orthomyxoviridae, Bunyaviridac, or Adenoviridac could cause this disease . Differentiate among these families by method of transmission, morphology, nucleic acid, and type of replication. The reservoir for this disease is mice. Name the disease .
...
A 65 year old man presents to the hospital with a one week history of.docx
A 65 year old man presents to the hospital with a one week history of malaise, headache, fever, and chils. He is admitted and over the next week his disease progressed with a worsening cough and shortness of breath. His physical exam was benign except for pulmonary compromise. The patient is current on all of their vaccinations and has no recent travel history. A chest radiograph showed multilobar infiltrates. Other significant laboratory findings include an elevated white blood cell count with increased polymorphonuclear neutrophils. Because the patient had a prior history of drug abuse and akcoholism, a toxicology screen and HIV serology were performed. Both were negative. A bronchoscopy was performed, with a bronchoalveolar lavage (BAL) showing many white blood cells, but no organisms. Calcofluor white stains for fungi and direct fluorescent-antibody stain (DFA) for Pneumocystis were also negative. Routine bacterial culture of the BAL was negative. An organism was recovered only on buffered charcoal yeast extract agar. Based on this information, what is the most likely pathogen? B. pertussis Lpneumophila H. influenzae Brucella spp.
.
Fever Of Unknown Origin
Contains 17 clinical situations of prolonged fever and discussion of various differential diagnosis based on them. Also gives the key points in the diagnosis of a prototype diagnosis and the usefulness of a relevant investigation modality in identifying these conditions. This power point presentaion is based on the chapter in Harrison's Text Book on Internal Medicine chapter on Fever of Unknown Origin
A 65 vear oid man presents to the hospital with a one week history of.docx
A 65 vear oid man presents to the hospital with a one week history of malaise, headache, fever, and chilis. He is admitted and over the next week his disease progressed with a worsening cough and shortness of breath. His physical exam was benign except for pulmonary compromise. The patient is current on all of their vaccinations and has no recent travel history. A chestradiograph showed multilobar infiltrates. Other sighificant laboratory findings include an elevated white blood cell count with increased polymorphonuclearneutrophils. Because the patient had a prior history of drug abuse and alcoholism, a toxicology screen and HIV serology were performed. Both were negative. A bronchoscopy was performed, with a bronchoalveolar lavage (BAL) showing many white blood cell5, but no organisms. Calcofluor white stains for fungi and direct fluorescent-antibody stain (DFA) for Pneumocystis were aiso negative. Routine bacterial culture of the BAL was negative. Question 1 1 pts Wny was the BAL routine bacterial culture negative? The pasients condtion is not due to a microorganism The pathogen is not a bacteniuin The pothosen a not present in BAL. Poutine bacteriat culfure was not surhcient to recover the puthogen Question 2 1 pts Gased on the patient shistory and condition, what teating should be pertormed next? Bit, pultive for Legionella An organism was recovered only on buffered charcoal yeast extract agar. Based on this information, what is the most likely pathogen? B. pertussis Lpneumophila H. influenzae Brucella spp: Question 4 The organism was most likely transmitted by: Handing of inimul prodicts Reipiratory droblets from an infected persen. Inhulation of water droplets An arthropod vectar lexin- tick Question 5 1 pts What other testing can be performed to detect this organism in a patient? Uinury ankgen testing Elektain testing Culuie supplementation with cystiane. Wea bienati trest
.
MCQs & Case Discussion- 2
Discussion on clinical cases of respiratory infections along with MCQs to test theoretical knowledge.
Coronavirus Disease-19 and Reinfections: A Review of Cases
Since first surfacing in Wuhan, China, in December 2019, the novel coronavirus disease-2019 (COVID-19) has led to a global pandemic with confirmed cases and death bells tolling in the millions with new cases still emerging daily. Despite sharing genetic similarities to the severe acute respiratory syndrome (SARS) virus, the specific viral proteins found on the novel SARS coronavirus 2 and its structure seems to make this strain much more elusive and destructive. Based on peer-reviewed cases, there seems to be an increase in patient reinfection, but due to current testing and treatment limitations, it is yet to be determined if the new trend of reinfection is due to a persistent COVID-19 infection that involves a latent period, a recurrent infection due to the same strain of COVID-19, or a mutated strain of COVID-19. The purpose of this study is to discuss the recent reports of the development of reinfection in previously confirmed COVID-19 cases in an attempt to gain a further understanding of the mechanisms of virulence, the effects on the human immune system, and how current testing and treatment modalities are faring. While the virus seems to have a penchant for patients with existing comorbidities, newer data indicate that everyone may be susceptible to possible infection and that not all patients will present with typical respiratory symptoms, making it imperative to examine established cases of reinfection in an attempt to further help with developing drugs for treatment, vaccines, and protocols for prevention.
Covid-19 and time 10 7-2020
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Timetable
Relapse
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treatment
transmission
infectivity
viral shedding
clinical picture
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pathogenesis
radiology
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Check a few updates about the covid19 diagnosis by Dr. gurbilas. He is a famous gastroenterologist in Chandigarh.
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COVID-19/ Coronavirus Disease 2019 General Information
Compiled by: Belachew Weldegebriel (bellachew@gmail.com)
Jimma University, Jimma, Ethiopia
Subclinical thyroiditis related to COVID-19: A case report and literature review
COVID-19 can cause different clinical manifestation by affecting
different organs in the body. Involvement of thyroid gland is very
rare in COVID-19 infection than any other systems of the body.
We described a 41-year-old female with subclinical thyroiditis
most likely related to corona virus infection and reviewed literatures regarding cases of thyroiditis due to COVID-19 have been
reported. The objective of this article is to create awareness regarding this novel entity and the association with thyroid dysfunction
Answer Clinical Application Questions 1-3 for Chapter 21 on page
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Answer Clinical Application Questions 1-3 for Chapter 21 on page 614
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2) A 12-year old diabetic girl using continuous subcutaneous insulin infusion to manager her diabetic developed a fever (39.4 degree C), low blood, abdominal pain, and erythroderma. She was supposed to change the needle-insertion site every 3 days after cleaning the skin with an iodine solution. Frequently she did not change the insertion site more often than every 10 days. Blood culture was negative, and abscesses at insertion sites were not cultured. What is the probable cause of her symptoms?
3)
A teenage male with confirmed influenza was hospitalized when he developed respiratory distress, He had a fever, rash, and low blood pressure. S. aureus was isolated from his respiratory secretions. Discuss the relationship between his symptoms and the etiological agent
Clinical Application Question 1-3 for Chapter 22 on page 642.
1)
A 1-year-0ld infant was lethargic and had a fever. When admitted to the hospital , he had multiple brain abscesses with gram-negative coccobacilli. Identify the disease, etiology, and treatment.
2)
A 40-year-old bird handler was admitted to the hospital with soreness over his upper jaw, progressive vision loss, and bladder dysfunction. He had been well 2 months earlier. Within weeks he lost reflexes in his lower extremities and subsequently died. Examination of CSF showed lymphocytes. What etiology do you suspect? What further information do you need?
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...
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Other cost factors such as extra managerial time may also have to be factored in.
Speed: Measured as time from when the shipment is released at the supplier's facility to the time
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Reliability: Sometimes described as fill rate. Refers to the ability to deliver on time. Can be
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The measure is thus the percentage of deliveries made within the specified window.
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rare in COVID-19 infection than any other systems of the body.
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Answer Clinical Application Questions 1-3 for Chapter 21 on page
Answer Clinical Application Questions 1-3 for Chapter 21 on page 614 and Clinical Application Question 1-3 for Chapter 22 on page 642. Answers should be submitted in a word document with any associated references used.
Answer Clinical Application Questions 1-3 for Chapter 21 on page 614
1) A hospitalized patient recovering from surgery develops an infection that has blue-green pus and a grapelike odor. What is the probable etiology? How might the patient have acquired this infection?
2) A 12-year old diabetic girl using continuous subcutaneous insulin infusion to manager her diabetic developed a fever (39.4 degree C), low blood, abdominal pain, and erythroderma. She was supposed to change the needle-insertion site every 3 days after cleaning the skin with an iodine solution. Frequently she did not change the insertion site more often than every 10 days. Blood culture was negative, and abscesses at insertion sites were not cultured. What is the probable cause of her symptoms?
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2)
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degree C. Examination of CSF revealed Gram-negative coccobacilli. Identify the disease and treatment
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Pan-Africanism
King Leopold.
Select a characleristic that is normally associated with Carrier grade.pdf
Select a characleristic that is normally associated with Carrier grade Answers: a, Low speech
quality Interoperability b. Average reliability (better that 80% ) c. Average call setup time d..
See figure 18-14- which summarizes hypotheses for why species richness.pdf
See figure 18.14 , which summarizes hypotheses for why species richness is higher in the tropics.
Panel B has an error that has confused students in previous years. What is the error? The blue
temperate line should be above the red tropical line. There is no problem with this panel If only
time available for diversification differs, both temperate and tropical species diversity should be
plotted on the same curve. Tropical should be plotted on the curve at younger times. If only time
available for diversification differs, both temperate and tropical curves should have the same
asymptote (reach the same level of species richness). FIGURE 18.14 Hypotheses Proposed to
Explain the Latitudinal Gradient in Species Richness (A) The tropics have a higher
diversification rate (speciation rate - extinction rate) than temperate areas do, so they have
accumulated species faster. (B) The tropics have had more time for diversification than
temperate areas have, so they have accumulated more species. (C) Because their productivity is
higher, the tropics have a higher carrying capacity than temperate areas, so more species can
coexist there. (After G. G. Mittelbach et al. 2007. Ecol Lett 10: 315-331.) Most lineages (species,
genera, and broader clades) in North and South America have very different evolutionary
histories since North America (Nearctic region) was once part of the supercontinent Laurasia.
Laurasia was separated from Gondowana (the supercontinent that contained South America
(Neotropic region) for more than 100 million years. Choose is the best explanation for this
pattern. The long separation limited dispersal until 60 million years ago. Different lineages
evolved on each continent. North and South America were separated until 6 million years ago,
limiting dispersal. Different lineages evolved on each continent. North and South America have
different abiotic conditions (different biomes), so different lineages have evolved on each
continent. Most species in North and South America have very similar evolutionary histories, but
North America has experienced a higher extinction rate due to habitat fragmentation and thus has
fewer species than South America. Terrestrial (on land) biodiversity is higher in tropical (near
the equator) than in temperate (midlatitude) regions. Which of the following best explains the
reason for this pattern? (Check all statements that you think apply.) Tropical regions have had a
longer evolutionary history than the northern and the southern hemispheres since the tropics
worked as a refuge during several ice ages. A longer evolutionary history means that species
have been able to diversify over a longer time. The annual average temperature in tropical
regions is more variable than in the northern and the southern hemispheres. Higher temperature
variability is likely to generate a wider variety of species. Tropical regions are more pristine,
with less human development and thus less species extinction. Tropical regions.
Security- One of the most appealing features of Linux systems are the.pdf
Security:
One of the most appealing features of Linux systems are the security features it possesses. Go
online and see if you can find any instance of a Linux-based system being hacked or otherwise
compromised. If you can find one, explain how the security features were circumvented..
Section 3- Ancient languages Question 13 0pts You will answer all the.pdf
Section 3: Ancient languages Question 13 0 pts You will answer all the questions in this section
about the same ancient witing system choose one of the following Oid Persian cuneiform Linear
B Egyptian heroglyphics Mayan hieroglyphics Question 14 10 pts What kind(s) of writing
system was it? (Alphabet, sydabary, logographic, etc) What was the crib used in the decipherfent
of that text? Deschbe in o word orphrase p (4) 0 worts / > Question 16 What was one other clie,
pattern of reasoning, or sol that you thik was persculdety important to the dedphement? Descrbe
in ane sentence:.
section 9 is highlighted- 3- Focus on Section 9- How can researchers.pdf
section 9 is highlighted.
3. Focus on Section 9. How can researchers and conservationists test for the presence of the
prion associated with CWD? Why is testing difficult? What is the treatment? Do your answers to
these questions make sense given your knowledge of protein structure and folding? for CWD
transmission to humans, one report rectal mucos, and brain in CWD positive elk. indicates
nonhuman primate susceptibility to alhough one of seven elk with early CWD CWD.
Intracerebral inoculation of squirrel was tonsil positive, but rectal mucosa negamonkeys (Saimini
sciureus) demonstrated a tive [82]. positive CWD transmission [49]. Among non- PrP detection
in CWD-infected deer human primates, however, the Pmp sequence: blood has been a challenge
to develop as an anof the new world monkeys are the most dis- temortem diagnostic tool. Prptic
was recently tant from humans [72], and therefore may not reported as detectable in deer blood
using an indicate that human prion protein conversion antibody ELISA with signal amplification
of would be induced by CWD PrP S c . antibody conjugated DNA catalyzed by T7 RNA
polymerase [15]. 1. CWD DIAGNOSTICS Protein misfolding cyclic amplification (PMCA) can
be used to amplify PrPir from Clinical kigns of CWD in deer and elk CWD-infected deer, and
should be valuable are unspecific and-subtle in cariy disease and for Prpes detection from tissues
and body flucommonly include weight loss and behav- ids containing low levels of infectivity.
for foral changes such as isolation from the herd improved understanding of CWD pathogeneand
depression. Other signs may include hy: improved understanding of CWD palso to detect
animals in early stages persalivation, polydipsia/polyuria, ataxia, and of infection [43]. Atarashi
et al. [3] developed occisionally increased regurgitation and/or of infection [43]. Atarashi ct al.
[3/ developed esophageal distension. Therefore sensitive, nique whereby recombinant, natively
folded specific, and rapid ante-mortem CWD ascays Pique whereby recombinant, natively folded
are eritical for accurafe diagnosis. Removal PrP monomers is used to amp 50 ag of PrPs was
detectable. Therefore of infected animals from a berd, pairticularly methods for sensitive
detection of Prpe are in US National Parks where culling of only subatantially improvingl known
infected individuals is often the preferred method of management ( M . Wild, personal
communication). To survey and man- 10. TOOLS FOR CWD RESEARCH: CELL. age CWD in
Rocky Mountain National Park IINES AND CERVID PrP EXPRESSING and adjacent Estes
Park in Colondo.male TRANSGENIC MICE deer were anesthetized, radiocollared, and ton-
Until recently, few techniques were availsil biopsies collected and tected (M. Wild, able to detect
CWD prion infectivity, or to personal communication: [941) Any prion: test compounds to
disrupt prion conversion. A infected animals were then located by ra- CWD-susceptible cell line
derived from cervid diotelemetry and euthani.
section 5-4 Suppose that there are 27 sophomores and 14 juniors in a P.pdf
section 5.4
Suppose that there are 27 sophomores and 14 juniors in a Physiology class. Two students are
chosen at random to participate in a class demonstration. What is the probability of choosing two
students at random and the first is a junior and the second one is a sophomore? Round your
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Section 1- DNA Technology - 30 marks Definitions- 1-1 A collection of.pdf
Section 1: DNA Technology - 30 marks Definitions: 1.1 A collection of clones that contain a
variety of DNA copies of mRNAs expressed in a particular cell type or tissue type. 1.2 An
enzyme that can cleave a DNA molecule at any site where a specific short sequence of
nucleotides occurs. 1.3 A clone of a DNA copy of an mRNA molecule. 1.4 The process whereby
two complementary nucleic acid strands form a double helix. 1.5 Small, circular DNA molecule
that replicates independently of the genome and can be used for DNA cloning. 1.6 A relative
molecular mass size marker used to identify the approximate size of a DNA molecule run on a
gel during electrophoresis..
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Search for a single, specific current issue associated with tropical coral reefs within the last year.
It should not be difficult to locate an issue, there are numerous publications and organizations
that are dedicated to the marine environment and will provide no shortage of current issues. 1)
Write a one paragraph summary of the current issue and include the complete reference in APA
format at the end..
Screen 1 -- display index page Once user clicks on List students.pdf
Screen 1 -> display index page
Once user clicks on List students
Takes you to screen 2
Clicking on details takes user to screen 3
Instructions :
Use JDBC to retrieve information from the database
Use Java POJO to map to correct object.
Use best practices for naming conventions, packaging structure and code style.
I have done with 2 webpages , only the third one is not giving the id information when i click on
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permision such a way that "others" can tead and execute the flile. Screen shot+ Explanition
+with time stamp. 4. Provide your Ie address, gateway, DtiCP server and DNS servee Are you
uking Dynamic or static iP address? Screen naot + Expluation + with time stanp. 5. Generate a
SstA key IN THE. ARST VM then distribute it to the second VM. Try to 5SH from first VM to
the second VM without entering pastword. Scroen shot +isplanation + with time yamp. 6.
Contigut ane VM as NFS Server and another VM as Nis client: Show that it is working, Serecui
shot + Explaration + with rime stamp.
Scores on a standard IQ test for the population has a mean of 100 and.pdf
Scores on a standard IQ test for the population has a mean of 100 and a standard deviation of 15.
John is convinced that her statistics class is way smarter than average. When she gives her class
(n=25) an IQ test, their average is 105. What is the probability that John's future class next
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Scope creep is a tool for risk assessment- Select one- True False If t.pdf
Scope creep is a tool for risk assessment. Select one: True False If the value of an asset is 400
OMR and exposure factor is 0.7 , what is SLE? Answer: What is NOT a benefit of a quantitative
RA? a. This is an Objective method b. Uses expert opinions. c. Uses simple mathematical
formulas. d. Can perform cost benefit analysis.
Scenario 2- Medical Records Release Form Patient is checking out and h.pdf
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for a consult. June, her MA scheduled an appointment for me already, but they told me to fill
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Scientists believe the earliest forms of life did not have both DNA an.pdf
Scientists believe the earliest forms of life did not have both DNA and RNA. Yet they were
still able to make proteins. Based on the processes described here, which do you think
evolved first- DNA or RNA? Please justify your answer. In other words, which molecule
could you more easily imagine a cell living without and still being able to make protein?.
Scenario 1- Suppose a population has a trait controlled by a gene with.pdf
Scenario 1: Suppose a population has a trait controlled by a gene with two alleles T and t, where
T is dominant to t (typical dominant/recessive genotype/phenotype relationship). The population
is in Hardy-Weinberg equilibrium and the frequency of the T allele is 0.39
1) How many individuals out of 364 total do you predict have the "tt" genotype?
2) How many individuals do you predict have the "T" phenotype?
3) How many heterozygotes do you predict there to be?
Scenario 2: Suppose a population has a trait controlled by a gene with two alleles B and b,
where B is dominant to b (typical dominant/recessive genotype/phenotype relationship). The
population is in Hardy-Weinberg equilibrium and there are 24 out of 256 with the "B"
phenotype.
4) What do you predict the frequency of the "b" allele to be?
5) How many of those 24 "B" phenotype individuals do you predict to be heterozygotes?.
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Saved Visitors to a Humane Society were asked how many snakes they have owned in their
lifetime. The mean was 0.3, the median was 2, and the skewness statistic was -2.75. Which best
describes this distribution? It is _______________________ Question 10 options: a normal
(Bell) curve a negatively skewed distribution a bimodal distribution a positively skewed
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Scenario -#2 Mike's boss is Tom- who as manager of the physician group.pdf
Scenario \#2 Mike's boss is Tom, who as manager of the physician group reports to one of the
four Division managers. Each of Mike's direct reports (Administrative Assistants) oversee 6
physician practices located within TruBlu Care. Directions: Create an Organizational Chart for
TruBlu Care beginning with the Division Manager to show the span of control. Be sure to
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Manager B. ? C. ? D. ? E. ?.
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