Most prescriptions will have locking caps for safety, and non-locking caps require a signature each time from the patient. Brown bottles are used for light- and heat-sensitive medications. Compounding can be done by pharmacists for individual prescriptions without recipes, by pharmacy technicians following written protocols for single treatments, or by technicians in bulk manufacturing for multiple patients. Prescription labels contain important pharmacy and patient information as well as dosing instructions, while shelf bottles must be checked for expiration and accuracy before and after dispensing medications which may have additional instructions or require medication guides.