Oral presentation by Lars Ramström at Workshop on tobacco ingredients, National Institute for Public Health and the Environment, Bilthoven, The Netherlands, 30 and 31 October 2003
Meaningful public education by labelling on tobacco packages: Some elements o...TobaccoFindings
Information provided on tobacco packages should clarify that:
1. A smoker's nicotine intake from cigarettes varies widely based on how they smoke and depends on their personal nicotine needs, not machine-measured yields.
2. Intake of other harmful substances depends on the brand-specific ratio of each substance to nicotine.
3. Health risk information should make clear that nicotine itself poses little risk, while combustion products in smoked tobacco are highly dangerous, and nicotine replacement therapies and smokeless tobacco are much less risky than smoking.
E-Cigarette Summit Speaker: Dr Lynne DawkinsLindsay Fox
Slides from Dr Lynne Dawkins' presentation at the E-Cigarette Summit, London November 12, 2013. Electronic Cigarettes: What are they, and are they effective?
Full summary of the E-Cigarette Summit: http://ecigarettereviewed.com/e-cigarette-summit-london-summary
Research on Tobacco Products Taxation for Global Tobacco ControlUCT ICO
This document summarizes research on tobacco taxation policies in the European Union. It identifies two main problems that prevent further reductions in combustible tobacco use: 1) a lack of convergence in cigarette and roll-your-own (RYO) tobacco prices across EU countries, which undermines domestic public health policies; and 2) a persistent price gap between cigarettes and cheaper RYO tobacco that has led consumers to shift toward RYO use. The document recommends reforms to the upcoming EU Tobacco Tax Directive to set minimum taxes per unit of product at levels that equalize taxes between cigarettes and RYO and encourage convergence of prices across countries.
The document discusses the European Tobacco Products Directive. Some key points:
- The Directive provides stronger regulation of tobacco products, ingredients, additives, and disclosure requirements. It aims to improve public health protection across the EU.
- Products like cigarettes, smokeless tobacco, e-cigarettes, and novel products will be regulated. Ingredients giving flavors or health impressions will be restricted. Misleading packaging and labeling will be prohibited.
- Implementation and monitoring plans include collecting industry data, tracking products, and evaluating the Directive's public health impact over 5 years using cohort and survey studies across 6 EU member states.
E-Cigarette Summit Speaker: Professor Robert WestLindsay Fox
Trends in electronic cigarette use in England
Slides from Prof Robert West's presentation at the E-Cigarette Summit, London November 12, 2013.
Full summary of the E-Cigarette Summit: http://ecigarettereviewed.com/e-cigarette-summit-london-summary
Research on Safety of Electronic Cigarettes - Dr. Konstantinos FarsalinosLindsay Fox
Research on Safety of Electronic Cigarettes
Slides from Dr. Konstantinos Farsalinos' presentation at the E-Cigarette Summit, London November 12, 2013.
Full summary of the E-Cigarette Summit: http://ecigarettereviewed.com/e-cigarette-summit-london-summary
Professor Robert West - E-Cigarette Summit 2014Neil Mclaren
- The document analyzes trends in electronic cigarette use in England based on monthly household surveys conducted by Robert West and colleagues at University College London.
- It finds that prevalence of e-cigarette use increased rapidly until late 2013 but has remained stable since, with 20% of smokers and 30% of recent ex-smokers now using e-cigarettes.
- E-cigarettes have become the most popular aid for quit attempts, and their increased use has been accompanied by rises in quit attempts and success rates at the population level.
Meaningful public education by labelling on tobacco packages: Some elements o...TobaccoFindings
Information provided on tobacco packages should clarify that:
1. A smoker's nicotine intake from cigarettes varies widely based on how they smoke and depends on their personal nicotine needs, not machine-measured yields.
2. Intake of other harmful substances depends on the brand-specific ratio of each substance to nicotine.
3. Health risk information should make clear that nicotine itself poses little risk, while combustion products in smoked tobacco are highly dangerous, and nicotine replacement therapies and smokeless tobacco are much less risky than smoking.
E-Cigarette Summit Speaker: Dr Lynne DawkinsLindsay Fox
Slides from Dr Lynne Dawkins' presentation at the E-Cigarette Summit, London November 12, 2013. Electronic Cigarettes: What are they, and are they effective?
Full summary of the E-Cigarette Summit: http://ecigarettereviewed.com/e-cigarette-summit-london-summary
Research on Tobacco Products Taxation for Global Tobacco ControlUCT ICO
This document summarizes research on tobacco taxation policies in the European Union. It identifies two main problems that prevent further reductions in combustible tobacco use: 1) a lack of convergence in cigarette and roll-your-own (RYO) tobacco prices across EU countries, which undermines domestic public health policies; and 2) a persistent price gap between cigarettes and cheaper RYO tobacco that has led consumers to shift toward RYO use. The document recommends reforms to the upcoming EU Tobacco Tax Directive to set minimum taxes per unit of product at levels that equalize taxes between cigarettes and RYO and encourage convergence of prices across countries.
The document discusses the European Tobacco Products Directive. Some key points:
- The Directive provides stronger regulation of tobacco products, ingredients, additives, and disclosure requirements. It aims to improve public health protection across the EU.
- Products like cigarettes, smokeless tobacco, e-cigarettes, and novel products will be regulated. Ingredients giving flavors or health impressions will be restricted. Misleading packaging and labeling will be prohibited.
- Implementation and monitoring plans include collecting industry data, tracking products, and evaluating the Directive's public health impact over 5 years using cohort and survey studies across 6 EU member states.
E-Cigarette Summit Speaker: Professor Robert WestLindsay Fox
Trends in electronic cigarette use in England
Slides from Prof Robert West's presentation at the E-Cigarette Summit, London November 12, 2013.
Full summary of the E-Cigarette Summit: http://ecigarettereviewed.com/e-cigarette-summit-london-summary
Research on Safety of Electronic Cigarettes - Dr. Konstantinos FarsalinosLindsay Fox
Research on Safety of Electronic Cigarettes
Slides from Dr. Konstantinos Farsalinos' presentation at the E-Cigarette Summit, London November 12, 2013.
Full summary of the E-Cigarette Summit: http://ecigarettereviewed.com/e-cigarette-summit-london-summary
Professor Robert West - E-Cigarette Summit 2014Neil Mclaren
- The document analyzes trends in electronic cigarette use in England based on monthly household surveys conducted by Robert West and colleagues at University College London.
- It finds that prevalence of e-cigarette use increased rapidly until late 2013 but has remained stable since, with 20% of smokers and 30% of recent ex-smokers now using e-cigarettes.
- E-cigarettes have become the most popular aid for quit attempts, and their increased use has been accompanied by rises in quit attempts and success rates at the population level.
The document discusses statistics on tobacco-related deaths from various WHO regions in 1998. It then discusses the percentage of total deaths attributable to tobacco use in different regions in 1990 and projections for 2020. The document also discusses why people smoke and maintain smoking habits, signs of nicotine addiction, classification of tobacco use disorders, and different intervention strategies to reduce tobacco-related harm including decreasing uptake, increasing cessation, and exploring potentially less harmful tobacco products.
The document discusses the dangers of drinking and driving according to various statistics. It states that over 10,000 people die from alcohol-related crashes each year in the US. Various organizations like MADD and CDC provide data showing that 1 in 3 people will be in an alcohol-related crash in their lifetime and that drunk driving costs each US adult around $500 per year. Prevention efforts through increased awareness have helped reduce drinking and driving incidents by 30% in the past 5 years.
Gamifying National Blood Service of Latvia - Gamification CertificationNatalija Knaidele
Gamification Certification Level 2 Project for the Engagement Alliance
The key motivation for blood donors is intrinsic – people want to help others. Qualifying potential donors who are not intrinsically motivated, can be, to a degree, motivated extrinsically. Gamification can help with that by targeting potential donors with the use of appropriate game mechanics.
The document outlines Stetson University's anti-hazing education plan and policies. It discusses (1) how hazing is strictly prohibited and defined, (2) relevant Florida state laws criminalizing hazing, and (3) Stetson's values of personal growth, intellectual development, and global citizenship that the anti-hazing plan supports. The plan aims to educate the university community on the dangers of hazing through facts, myths, self-reflection questions, and suggestions for alternative non-hazing activities.
This document outlines anti-hazing laws and penalties in the Philippines. It defines hazing as initiation practices that embarrass, humiliate or cause physical or psychological harm to recruits. Organizations must provide 7 days notice before any initiation. Representatives must supervise and ensure no physical harm occurs. Those who cause injury or death through hazing face penalties from life imprisonment to lesser jail time depending on the consequences. School officials and parents can be accomplices if they enable or fail to prevent hazing.
This document defines key terms related to dangerous drugs and outlines the Comprehensive Dangerous Drugs Act of 2002 in the Philippines. It defines drugs, recreational drugs, and provides a list of the top 10 most dangerous drugs. It then outlines the unlawful acts, penalties, agencies responsible for enforcement, and programs for treatment and rehabilitation of drug dependence.
The DOH approves some medical techniques that are not commonly accepted in the field, and these are called traditional and alternative.
Disclaimer: No types of traditional and alternative medicine specified. But there is the RA 8423 of Traditional and Alternative Medicine Act of 1997 :3
Republic Act 8504: Philippine AIDS Prevention and Control Act of 1998Frenz Delgado
The document discusses Republic Act 8504, also known as the Philippine AIDS Prevention and Control Act of 1998. The law aims to strengthen the Philippines' response to HIV/AIDS through comprehensive provisions covering prevention, education, monitoring, protection of human rights, and strengthening the Philippine National AIDS Council. It also mandates implementing rules and regulations. However, lawmakers now seek to amend the law as it is outdated given the rising rate of new HIV infections in the Philippines.
The Reproductive Health Bills, popularly known as the RH Bills, are legislative bills aiming to guarantee universal access to reproductive health care services, supplies and information in the Philippines. There are presently six bills with the same goals, the most prominent of which is House Bill 96 but they are all referred to in the country as "the RH Bill" as they have the common purpose of promoting reproductive health, responsible parenthood and informed choice in conformity with internationally recognized human rights standards. The contentious aspect of the bill which has spawned a national debate is its key proposal that the government funds and undertakes widespread distribution of family planning devices such as oral contraceptive pills (OCPs) and IUDs, dissemination of information on their use, and enforcement of their provision in all health care centers and private companies, as a way of controlling the population of the Philippines. The bill is based on the premise that present population growth impedes economic development and exacerbates poverty.
The document outlines the Republic Act 9775 or the "Anti-Child Pornography Act of 2009" in the Philippines. It defines child pornography and lists various prohibited acts related to child pornography along with corresponding penalties. These include hiring a child for pornography, producing/distributing child pornography, and knowingly providing venues for child pornography. The document also outlines responsibilities of internet service providers, internet content hosts, mall owners, and others in reporting instances of child pornography.
The document discusses consumer protection laws and policies. It defines key terms like consumer and consumer protection. The objectives of consumer protection laws are to protect consumers' health, safety, rights and interests from unfair business practices. These laws regulate food, drugs, cosmetics and other consumer products to ensure they meet quality, safety and labeling standards. Government agencies implement and enforce these consumer protection laws.
- The document discusses nicotine testing methods and their use in various contexts like insurance, employment, schools, and research. It also covers nicotine metabolism and the differences between nicotine and its metabolite cotinine.
- The Nano-Check Rapid Nicotine Test is described as an immunoassay that detects cotinine in urine at cutoff levels of 200ng/ml or 500ng/ml to determine tobacco use. It provides results in 5-10 minutes and is intended for professional use.
- The test works by detecting cotinine in a urine sample via monoclonal antibodies on a test strip, with positive or negative results depending on whether or not a test line appears within the timeframe.
Tobacco is a plant grown for its leaves, which contain the addictive drug nicotine. Nicotine causes the release of endorphins that make people feel good in the short term but is highly addictive. Tobacco use leads to serious health issues like cancer, heart disease, and death. The WHO Framework Convention on Tobacco Control aims to address the global tobacco epidemic. In India, the National Tobacco Control Programme was launched in 2007 to increase awareness, reduce tobacco use and production, and enforce tobacco control laws. It operates at national, state, and district levels to implement strategies like public education campaigns, enforcement of advertising bans, and increasing access to cessation resources.
The document discusses tobacco taxation in India. It analyzes data from the Global Adult Tobacco Survey from 2009-2010 which shows that 34.6% of Indian adults consume tobacco in some form. Tobacco consumption prevalence is higher in rural areas compared to urban areas. The document estimates the number of adults who currently smoke cigarettes, bidis, and use smokeless tobacco. It also provides estimates of own-price elasticities of demand for different tobacco products. Using these elasticities, it analyzes how a 10% increase in tobacco prices resulting from taxation would impact tobacco consumption levels and government revenues.
The document discusses tobacco taxation in India. It analyzes data from the Global Adult Tobacco Survey from 2009-2010 which shows that 34.6% of Indian adults consume tobacco in some form. Tobacco consumption prevalence is higher in rural areas compared to urban areas. The document estimates the number of smokers of different tobacco products and finds that there are over 274 million tobacco users in India. It analyzes own-price elasticities of tobacco products estimated in previous studies. A 10% price increase resulting from taxes is estimated to decrease bidi consumption more than cigarette consumption based on the relative elasticities of demand. Higher taxes could thus potentially reduce tobacco use and related health impacts while also increasing government revenue.
The UK government will regulate e-cigarettes and other nicotine containing products as medicines beginning in 2016 to ensure safety and quality. This decision aligns with proposed European regulation and manufacturers will have until 2016 to obtain licenses for their products, though they can seek licenses earlier. Regulating these products as medicines means high quality products can support smokers to reduce and quit smoking. Licensed products will be available over the counter or by prescription through the NHS and can be advertised like other medicines.
Chemistry and Effect of Nicotine, Smoking Pollution and Stopping it under Sec...ijtsrd
“Chemistry,” includes a brief description of technologies used by cigarette manufacturers in a limited number of cigarette brands marketed as “reduced exposure” or “lower yield” products. These commercial products have not been met with widespread consumer acceptance. The following section, “Biomarkers,” focuses on the manufactured tobacco burning cigarette consumed by the majority of smokers in the United States and elsewhere. The review on “Chemistry” describes the chemical components of cigarette smoke and addresses aspects of product design that alter the components of cigarette smoke and factors affecting delivery of smoke to the smoker. In most cases, the data reported for chemical levels in mainstream smoke were derived under standard smoking conditions described by the U.S. Federal Trade Commission FTC and the International Organization for Standardization ISO . These standard conditions are puff volume of 35 milliliters mL , two second puff duration, one minute puff frequency, and butt length defined as either 23 millimeters mm for nonfilter cigarettes or the length of the filter overwrap paper plus 3 mm. When alternative smoking regimens are used, levels of potentially harmful substances in smoke emissions usually differ from those measured under standard conditions. For more details, see “Delivery of Chemical Constituents into Tobacco Smoke” later in this chapter. When people smoke, they do not use the puff volume and puff frequency programmed into smoking machines, and smoking habits vary significantly from person to person and cigarette to cigarette. Consequently, actual exposures to and doses of components of smoke cannot be derived from values obtained with machine smoking. Cigarette smoke is a complex mixture of chemical compounds that are bound to aerosol particles or are free in the gas phase. Chemical compounds in tobacco can be distilled into smoke or can react to form other constituents that are then distilled to smoke. Researchers have estimated that cigarette smoke has 7,357 chemical compounds from many different classes .In assessing the nature of tobacco smoke, scientists must consider chemical composition, concentrations of components, particle size, and particle charge. These characteristics vary with the cigarette design and the chemical nature of the product.Scientists suggested an approach to identify the chemical components in tobacco smoke with the greatest potential for toxic effects. They considered the risk for cancer, cardiovascular disease, and heart disease. Using this approach, these investigators found that 1,3 butadiene presented by far the most significant cancer risk acrolein and acetaldehyde had the greatest potential to be respiratory irritants and cyanide, arsenic, and the cresols were the primary sources of cardiovascular risk. Other chemical classes of concern include other metals, N nitrosamines, and polycyclic aromatic hydrocarbons PAHs . This evaluation, along with the Hoffmann list of biol
ELECTRONIC CIGARETTES IN THE EU TOBACCO PRODUCTS DIRECTIVEUCT ICO
The Directive regulates electronic cigarettes and herbal smoking products in the EU. It sets limits on nicotine content, liquid volume, and additives. Products must be child-resistant, tamper-proof, and include warnings and a list of ingredients. Advertising of e-cigarettes is prohibited except between industry professionals. Member States must monitor for adverse health effects and share information.
This report discusses tobacco pricing and taxation in the United States. It finds that tobacco taxes have not kept pace with inflation since 1964, making cigarettes more affordable over time. As a result, cigarettes account for a smaller percentage of retail price today compared to 1964. The report examines studies on the price elasticity of tobacco, which suggest that higher taxes can effectively reduce tobacco consumption, though estimates vary. It argues that increasing tobacco taxes is a potent policy tool for tobacco control.
The document discusses statistics on tobacco-related deaths from various WHO regions in 1998. It then discusses the percentage of total deaths attributable to tobacco use in different regions in 1990 and projections for 2020. The document also discusses why people smoke and maintain smoking habits, signs of nicotine addiction, classification of tobacco use disorders, and different intervention strategies to reduce tobacco-related harm including decreasing uptake, increasing cessation, and exploring potentially less harmful tobacco products.
The document discusses the dangers of drinking and driving according to various statistics. It states that over 10,000 people die from alcohol-related crashes each year in the US. Various organizations like MADD and CDC provide data showing that 1 in 3 people will be in an alcohol-related crash in their lifetime and that drunk driving costs each US adult around $500 per year. Prevention efforts through increased awareness have helped reduce drinking and driving incidents by 30% in the past 5 years.
Gamifying National Blood Service of Latvia - Gamification CertificationNatalija Knaidele
Gamification Certification Level 2 Project for the Engagement Alliance
The key motivation for blood donors is intrinsic – people want to help others. Qualifying potential donors who are not intrinsically motivated, can be, to a degree, motivated extrinsically. Gamification can help with that by targeting potential donors with the use of appropriate game mechanics.
The document outlines Stetson University's anti-hazing education plan and policies. It discusses (1) how hazing is strictly prohibited and defined, (2) relevant Florida state laws criminalizing hazing, and (3) Stetson's values of personal growth, intellectual development, and global citizenship that the anti-hazing plan supports. The plan aims to educate the university community on the dangers of hazing through facts, myths, self-reflection questions, and suggestions for alternative non-hazing activities.
This document outlines anti-hazing laws and penalties in the Philippines. It defines hazing as initiation practices that embarrass, humiliate or cause physical or psychological harm to recruits. Organizations must provide 7 days notice before any initiation. Representatives must supervise and ensure no physical harm occurs. Those who cause injury or death through hazing face penalties from life imprisonment to lesser jail time depending on the consequences. School officials and parents can be accomplices if they enable or fail to prevent hazing.
This document defines key terms related to dangerous drugs and outlines the Comprehensive Dangerous Drugs Act of 2002 in the Philippines. It defines drugs, recreational drugs, and provides a list of the top 10 most dangerous drugs. It then outlines the unlawful acts, penalties, agencies responsible for enforcement, and programs for treatment and rehabilitation of drug dependence.
The DOH approves some medical techniques that are not commonly accepted in the field, and these are called traditional and alternative.
Disclaimer: No types of traditional and alternative medicine specified. But there is the RA 8423 of Traditional and Alternative Medicine Act of 1997 :3
Republic Act 8504: Philippine AIDS Prevention and Control Act of 1998Frenz Delgado
The document discusses Republic Act 8504, also known as the Philippine AIDS Prevention and Control Act of 1998. The law aims to strengthen the Philippines' response to HIV/AIDS through comprehensive provisions covering prevention, education, monitoring, protection of human rights, and strengthening the Philippine National AIDS Council. It also mandates implementing rules and regulations. However, lawmakers now seek to amend the law as it is outdated given the rising rate of new HIV infections in the Philippines.
The Reproductive Health Bills, popularly known as the RH Bills, are legislative bills aiming to guarantee universal access to reproductive health care services, supplies and information in the Philippines. There are presently six bills with the same goals, the most prominent of which is House Bill 96 but they are all referred to in the country as "the RH Bill" as they have the common purpose of promoting reproductive health, responsible parenthood and informed choice in conformity with internationally recognized human rights standards. The contentious aspect of the bill which has spawned a national debate is its key proposal that the government funds and undertakes widespread distribution of family planning devices such as oral contraceptive pills (OCPs) and IUDs, dissemination of information on their use, and enforcement of their provision in all health care centers and private companies, as a way of controlling the population of the Philippines. The bill is based on the premise that present population growth impedes economic development and exacerbates poverty.
The document outlines the Republic Act 9775 or the "Anti-Child Pornography Act of 2009" in the Philippines. It defines child pornography and lists various prohibited acts related to child pornography along with corresponding penalties. These include hiring a child for pornography, producing/distributing child pornography, and knowingly providing venues for child pornography. The document also outlines responsibilities of internet service providers, internet content hosts, mall owners, and others in reporting instances of child pornography.
The document discusses consumer protection laws and policies. It defines key terms like consumer and consumer protection. The objectives of consumer protection laws are to protect consumers' health, safety, rights and interests from unfair business practices. These laws regulate food, drugs, cosmetics and other consumer products to ensure they meet quality, safety and labeling standards. Government agencies implement and enforce these consumer protection laws.
- The document discusses nicotine testing methods and their use in various contexts like insurance, employment, schools, and research. It also covers nicotine metabolism and the differences between nicotine and its metabolite cotinine.
- The Nano-Check Rapid Nicotine Test is described as an immunoassay that detects cotinine in urine at cutoff levels of 200ng/ml or 500ng/ml to determine tobacco use. It provides results in 5-10 minutes and is intended for professional use.
- The test works by detecting cotinine in a urine sample via monoclonal antibodies on a test strip, with positive or negative results depending on whether or not a test line appears within the timeframe.
Tobacco is a plant grown for its leaves, which contain the addictive drug nicotine. Nicotine causes the release of endorphins that make people feel good in the short term but is highly addictive. Tobacco use leads to serious health issues like cancer, heart disease, and death. The WHO Framework Convention on Tobacco Control aims to address the global tobacco epidemic. In India, the National Tobacco Control Programme was launched in 2007 to increase awareness, reduce tobacco use and production, and enforce tobacco control laws. It operates at national, state, and district levels to implement strategies like public education campaigns, enforcement of advertising bans, and increasing access to cessation resources.
The document discusses tobacco taxation in India. It analyzes data from the Global Adult Tobacco Survey from 2009-2010 which shows that 34.6% of Indian adults consume tobacco in some form. Tobacco consumption prevalence is higher in rural areas compared to urban areas. The document estimates the number of adults who currently smoke cigarettes, bidis, and use smokeless tobacco. It also provides estimates of own-price elasticities of demand for different tobacco products. Using these elasticities, it analyzes how a 10% increase in tobacco prices resulting from taxation would impact tobacco consumption levels and government revenues.
The document discusses tobacco taxation in India. It analyzes data from the Global Adult Tobacco Survey from 2009-2010 which shows that 34.6% of Indian adults consume tobacco in some form. Tobacco consumption prevalence is higher in rural areas compared to urban areas. The document estimates the number of smokers of different tobacco products and finds that there are over 274 million tobacco users in India. It analyzes own-price elasticities of tobacco products estimated in previous studies. A 10% price increase resulting from taxes is estimated to decrease bidi consumption more than cigarette consumption based on the relative elasticities of demand. Higher taxes could thus potentially reduce tobacco use and related health impacts while also increasing government revenue.
The UK government will regulate e-cigarettes and other nicotine containing products as medicines beginning in 2016 to ensure safety and quality. This decision aligns with proposed European regulation and manufacturers will have until 2016 to obtain licenses for their products, though they can seek licenses earlier. Regulating these products as medicines means high quality products can support smokers to reduce and quit smoking. Licensed products will be available over the counter or by prescription through the NHS and can be advertised like other medicines.
Chemistry and Effect of Nicotine, Smoking Pollution and Stopping it under Sec...ijtsrd
“Chemistry,” includes a brief description of technologies used by cigarette manufacturers in a limited number of cigarette brands marketed as “reduced exposure” or “lower yield” products. These commercial products have not been met with widespread consumer acceptance. The following section, “Biomarkers,” focuses on the manufactured tobacco burning cigarette consumed by the majority of smokers in the United States and elsewhere. The review on “Chemistry” describes the chemical components of cigarette smoke and addresses aspects of product design that alter the components of cigarette smoke and factors affecting delivery of smoke to the smoker. In most cases, the data reported for chemical levels in mainstream smoke were derived under standard smoking conditions described by the U.S. Federal Trade Commission FTC and the International Organization for Standardization ISO . These standard conditions are puff volume of 35 milliliters mL , two second puff duration, one minute puff frequency, and butt length defined as either 23 millimeters mm for nonfilter cigarettes or the length of the filter overwrap paper plus 3 mm. When alternative smoking regimens are used, levels of potentially harmful substances in smoke emissions usually differ from those measured under standard conditions. For more details, see “Delivery of Chemical Constituents into Tobacco Smoke” later in this chapter. When people smoke, they do not use the puff volume and puff frequency programmed into smoking machines, and smoking habits vary significantly from person to person and cigarette to cigarette. Consequently, actual exposures to and doses of components of smoke cannot be derived from values obtained with machine smoking. Cigarette smoke is a complex mixture of chemical compounds that are bound to aerosol particles or are free in the gas phase. Chemical compounds in tobacco can be distilled into smoke or can react to form other constituents that are then distilled to smoke. Researchers have estimated that cigarette smoke has 7,357 chemical compounds from many different classes .In assessing the nature of tobacco smoke, scientists must consider chemical composition, concentrations of components, particle size, and particle charge. These characteristics vary with the cigarette design and the chemical nature of the product.Scientists suggested an approach to identify the chemical components in tobacco smoke with the greatest potential for toxic effects. They considered the risk for cancer, cardiovascular disease, and heart disease. Using this approach, these investigators found that 1,3 butadiene presented by far the most significant cancer risk acrolein and acetaldehyde had the greatest potential to be respiratory irritants and cyanide, arsenic, and the cresols were the primary sources of cardiovascular risk. Other chemical classes of concern include other metals, N nitrosamines, and polycyclic aromatic hydrocarbons PAHs . This evaluation, along with the Hoffmann list of biol
ELECTRONIC CIGARETTES IN THE EU TOBACCO PRODUCTS DIRECTIVEUCT ICO
The Directive regulates electronic cigarettes and herbal smoking products in the EU. It sets limits on nicotine content, liquid volume, and additives. Products must be child-resistant, tamper-proof, and include warnings and a list of ingredients. Advertising of e-cigarettes is prohibited except between industry professionals. Member States must monitor for adverse health effects and share information.
This report discusses tobacco pricing and taxation in the United States. It finds that tobacco taxes have not kept pace with inflation since 1964, making cigarettes more affordable over time. As a result, cigarettes account for a smaller percentage of retail price today compared to 1964. The report examines studies on the price elasticity of tobacco, which suggest that higher taxes can effectively reduce tobacco consumption, though estimates vary. It argues that increasing tobacco taxes is a potent policy tool for tobacco control.
Professor J.F. Etter - E-Cigarette Summit 2014Neil Mclaren
Professor Jean-François Etter discusses the evolving e-cigarette and vaporizer market. He notes that major tobacco companies like Philip Morris and British American Tobacco are now major players in the e-cigarette industry through brands like iQos and Voke. Independent research on these new products is needed, as the tobacco industry's past shows a history of deception. Frameworks for managing conflicts of interest are crucial to preserve the integrity of research and public trust. Academia must thoughtfully rethink interactions with industries producing nicotine and tobacco vaporizers.
An Experimental Method to Determine the Concentration of Nicotine in Exhaled ...Fontem Ventures
- An experimental method was presented to determine the concentration of nicotine in exhaled breath after using e-cigarettes and the nicotine retention rate.
- Three experienced e-cigarette users vaped e-cigarettes containing different nicotine concentrations while a smoking topography analyzer recorded puff volume and duration. This allowed determining the nicotine concentration inhaled per puff.
- A PTR-MS instrument then measured nicotine in exhaled breath, allowing calculation of the retention rate by comparing to the inhaled nicotine concentration. Over 99% of nicotine was retained when inhaled and 86% when held in the mouth. Exhaled nicotine concentrations were low (1.8-1786 ppb
This document summarizes information about tobacco and cancer. It covers the history of tobacco use, prevalence in India, carcinogens in tobacco smoke, how tobacco leads to cancer development, biomarkers, treatment risks for cancer patients who smoke or use smokeless tobacco, nicotine replacement therapy, and anti-tobacco campaigns in India. The document discusses the various types of tobacco products, evolution of cigarettes to reduce tar but increase other carcinogens, and campaigns to control tobacco labeling and marketing.
This document summarizes research on electronic nicotine delivery systems (ENDS) in the United States and implications for further research and policy. It defines ENDS and reviews available data on their components, vaporization process, use, and refilling. Testing of devices found variability in nicotine levels delivered and presence of contaminants. Research is needed to understand health effects, maximum safe doses, and impacts on smoking behaviors. Policy debates center around how to regulate ENDS and what constitutes a tobacco product.
The document discusses how e-cigarettes should be regulated. It presents evidence that e-cigarettes are safer than cigarettes and are used mostly by smokers to help quit smoking. It analyzes the current regulations in the US, UK, and EU and argues that regulating e-cigarettes as tobacco products or medicines would be disproportionate and could negatively impact public health goals. Instead, it advocates for regulating e-cigarettes as consumer products, with additional product standards and restrictions on youth access, similar to other consumer goods. The goal of regulation should be to balance public health benefits with limiting risks, without making e-cigarettes less competitive than cigarettes.
How E-Cigarettes Should be Regulated - Professor Jean-François ETTER - E-Ciga...Lindsay Fox
1) E-cigarettes are mostly used by smokers and help some quit or reduce smoking. Regular use by non-smokers has not been documented. E-cigarettes are less toxic than cigarettes.
2) Regulations of e-cigarettes vary by country and are currently evolving. The document discusses potential regulations as tobacco products, medications, or consumer products.
3) Regulating e-cigarettes as medications poses several problems and may stifle innovation, give the market to big tobacco, and result in fewer smokers quitting. Consumer product regulation with additional safety standards may better balance public health and individual freedom.
Heated Tobacco Products Create Side-Stream Emissions: Implications for Regula...Fontem Ventures
The document summarizes a study that investigated whether a heated tobacco product produced side-stream emissions. The study found that when the heated tobacco product was activated and during use, it released a large number of chemical compounds into the surrounding air, indicating the presence of side-stream emissions. In contrast, a nicotine inhaler and e-cigarette did not release similar emissions. As public health authorities state that any level of exposure to tobacco emissions is unsafe, the findings suggest that heated tobacco products should be subject to the same regulations as cigarettes regarding indoor use.
India has a significant tobacco problem, with 16% of smokers globally living in India. Tobacco use causes over 2,500 deaths per day in India. Several laws and policies have been implemented to reduce tobacco use. The Cigarettes and Other Tobacco Products Act of 2003 expanded regulations to include all tobacco products and required larger health warnings. Executive orders have also targeted tobacco, such as banning scenes depicting tobacco use in films. Other measures include prohibiting indoor smoking in public places and imposing taxes on tobacco. However, myths still exist around the economic and health impacts of tobacco that require addressing to curb its widespread use in India.
Similar to Regulation of tobacco ingredients for largest possible reduction of health risks (20)
Perception of health status among different groups of tobacco users in SwedenTobaccoFindings
This document summarizes a study comparing self-reported health perceptions among different groups of tobacco users in Sweden. The study found that:
1) Current daily smokers reported poorer satisfaction with their health, life, and higher numbers of sick days than other groups.
2) Daily snus users, both with and without a history of smoking, reported health perceptions similar to non-users and better than current smokers.
3) Former smokers who now use snus daily reported better mental health and life satisfaction than current smokers.
The results suggest that smoking impairs perceived health while switching from smoking to snus may improve it.
Snus as a Substitution for Smoking: The Swedish ExperienceTobaccoFindings
The document summarizes a study on tobacco use in Sweden. It finds that among males, use of snus (a form of smokeless tobacco) is more common than smoking, but less common among females. Snus seems to reduce smoking initiation and increase smoking cessation rates. The study shows snus is an effective smoking cessation aid commonly used by males in Sweden.
The role of harm reduction in tobacco controlTobaccoFindings
The document discusses the role of harm reduction in tobacco control. It argues that for current tobacco users who cannot quit, switching to a nicotine product that is markedly less harmful than cigarettes, such as nicotine replacement therapy or low-nitrosamine smokeless tobacco, can significantly reduce health risks compared to continuing smoking. While prevention and smoking cessation efforts are important, harm reduction strategies are also needed to help smokers unable or unwilling to quit nicotine use altogether. Regulating alternative nicotine products to ensure they are much safer than cigarettes can achieve public health benefits as part of a comprehensive approach to tobacco control.
The rationale for establishing low-toxicity smokeless nicotine product polici...TobaccoFindings
The document discusses tobacco harm reduction through the use of low-toxicity smokeless tobacco products like Swedish snus. It summarizes evidence from Swedish population studies that finds little risk of snus leading to smoking, strengthening nicotine addiction, or weakening smokers' efforts to quit. The evidence suggests that snus use can substantially reduce tobacco-related disease risk and that some smokers who switch to snus do subsequently quit nicotine altogether. There is little scientific evidence to support arguments against tobacco harm reduction and good evidence to reject such arguments.
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
Applications of NMR in Protein Structure Prediction.pptxAnagha R Anil
This presentation explores the pivotal role of Nuclear Magnetic Resonance (NMR) spectroscopy in predicting protein structures. It delves into the methodologies, advancements, and applications of NMR in determining the three-dimensional configurations of proteins, which is crucial for understanding their function and interactions.
The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14...Donc Test
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
Receptor Discordance in Breast Carcinoma During the Course of Life
Definition:
Receptor discordance refers to changes in the status of hormone receptors (estrogen receptor ERα, progesterone receptor PgR, and HER2) in breast cancer tumors over time or between primary and metastatic sites.
Causes:
Tumor Evolution:
Genetic and epigenetic changes during tumor progression can lead to alterations in receptor status.
Treatment Effects:
Therapies, especially endocrine and targeted therapies, can selectively pressure tumor cells, causing shifts in receptor expression.
Heterogeneity:
Inherent heterogeneity within the tumor can result in subpopulations of cells with different receptor statuses.
Impact on Treatment:
Therapeutic Resistance:
Loss of ERα or PgR can lead to resistance to endocrine therapies.
HER2 discordance affects the efficacy of HER2-targeted treatments.
Treatment Adjustment:
Regular reassessment of receptor status may be necessary to adjust treatment strategies appropriately.
Clinical Implications:
Prognosis:
Receptor discordance is often associated with a poorer prognosis.
Biopsies:
Obtaining biopsies from metastatic sites is crucial for accurate receptor status assessment and effective treatment planning.
Monitoring:
Continuous monitoring of receptor status throughout the disease course can guide personalized therapy adjustments.
Understanding and managing receptor discordance is essential for optimizing treatment outcomes and improving the prognosis for breast cancer patients.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
Nutritional deficiency Disorder are problems in india.
It is very important to learn about Indian child's nutritional parameters as well the Disease related to alteration in their Nutrition.
Can Traditional Chinese Medicine Treat Blocked Fallopian Tubes.pptxFFragrant
There are many traditional Chinese medicine therapies to treat blocked fallopian tubes. And herbal medicine Fuyan Pill is one of the more effective choices.
Allopurinol, a uric acid synthesis inhibitor acts by inhibiting Xanthine oxidase competitively as well as non- competitively, Whereas Oxypurinol is a non-competitive inhibitor of xanthine oxidase.
Storyboard on Acne-Innovative Learning-M. pharm. (2nd sem.) CosmeticsMuskanShingari
Acne is a common skin condition that occurs when hair follicles become clogged with oil and dead skin cells. It typically manifests as pimples, blackheads, or whiteheads, often on the face, chest, shoulders, or back. Acne can range from mild to severe and may cause emotional distress and scarring in some cases.
**Causes:**
1. **Excess Oil Production:** Hormonal changes during adolescence or certain times in adulthood can increase sebum (oil) production, leading to clogged pores.
2. **Clogged Pores:** When dead skin cells and oil block hair follicles, bacteria (usually Propionibacterium acnes) can thrive, causing inflammation and acne lesions.
3. **Hormonal Factors:** Fluctuations in hormone levels, such as during puberty, menstrual cycles, pregnancy, or certain medical conditions, can contribute to acne.
4. **Genetics:** A family history of acne can increase the likelihood of developing the condition.
**Types of Acne:**
- **Whiteheads:** Closed plugged pores.
- **Blackheads:** Open plugged pores with a dark surface.
- **Papules:** Small red, tender bumps.
- **Pustules:** Pimples with pus at their tips.
- **Nodules:** Large, solid, painful lumps beneath the surface.
- **Cysts:** Painful, pus-filled lumps beneath the surface that can cause scarring.
**Treatment:**
Treatment depends on the severity and type of acne but may include:
- **Topical Treatments:** Such as benzoyl peroxide, salicylic acid, or retinoids to reduce bacteria and unclog pores.
- **Oral Medications:** Antibiotics or oral contraceptives for hormonal acne.
- **Procedures:** Such as chemical peels, extraction of comedones, or light therapy for more severe cases.
**Prevention and Management:**
- **Cleanse:** Regularly wash skin with a gentle cleanser.
- **Moisturize:** Use non-comedogenic moisturizers to keep skin hydrated without clogging pores.
- **Avoid Irritants:** Such as harsh cosmetics or excessive scrubbing.
- **Sun Protection:** Use sunscreen to prevent exacerbation of acne scars and inflammation.
Acne treatment can take time, and consistency in skincare routines and treatments is crucial. Consulting a dermatologist can help tailor a treatment plan that suits individual needs and reduces the risk of scarring or long-term skin damage.
This presentation gives information on the pharmacology of Prostaglandins, Thromboxanes and Leukotrienes i.e. Eicosanoids. Eicosanoids are signaling molecules derived from polyunsaturated fatty acids like arachidonic acid. They are involved in complex control over inflammation, immunity, and the central nervous system. Eicosanoids are synthesized through the enzymatic oxidation of fatty acids by cyclooxygenase and lipoxygenase enzymes. They have short half-lives and act locally through autocrine and paracrine signaling.
Pharmacology of Prostaglandins, Thromboxanes and Leukotrienes
Regulation of tobacco ingredients for largest possible reduction of health risks
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2. Regulation of: - amounts of various constituents in cigarette smoke - information on packages regarding smoke constituents - smokefree tobacco products
3. To be meaningful from health point of view, regulation of smoke constituents should relate, not to machine yield , but to smokers’ intake, taking into account the interaction between the smoker and the product.
4. Jarvis MJ, Boreham R, Primatesta P, Feyerabend C, Bryant A. N icotine yield from machine-smoked cigarettes and nicotine intakes in smokers: evidence from a representative population survey. J Natl Cancer Inst. 2001 Jan 17;93(2):134-8 .
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8. In I 2001, the U.S. National Cancer Institute (NCI) published Monograph 13
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12. A smoker’s intake of substance A = machine yield of A (his nicotine intake) × machine yield of nicotine Amount of nicotine RATIO substance A / nicotine determined by determined by the smoker cigarette properties
15. Example of rule in an ”intake-related” regulation of cigarette smoke constituents . T/N ratio <10 (and, optionally Machine yield of tar <12 mg Machine yield of nicotine <1.4 mg)
17. Regulation of: - amounts of various constituents in cigarette smoke - information on packages regarding smoke constituents - smokefree tobacco products
18. Health-related purpose of consumer info on cigarette packages: To help the smoker minimize his intake of harmful smoke constituents. Therefore, info should be related to potential INTAKE. Consequently, machine yield figures are meaningless.
19. Machine yield figures on packages are even MISLEADING, since their appearence gives the false impression that: - nicotine intake were determined by cigarette properties and differing widely between different brands but independent of how you smoke. - low figures for a substance, e.g. tar, would indicate low intake of that substance i.e. ”This is a mild cigarette”.
20. Instead, smokers should be aware... - that they are themselves influencing their intake by the way they smoke - that the self-determined intake of nicotine is about the same from all cigarettes - that the intake of other substances is influenced also by cigarette properties (yield ratio to nicotine)
21. Possible model for a meaningful and truthful info box on packages : Nicotine delivery from one of these cigarettes - to a smoking machine (ISO standard): 0.6 mg - to a smoker: 0.1 – 2.0 mg depending on how it is smoked Every milligram of nicotine is accompanied by: Tar: 8 mg Carbon monoxide: 9 mg
22. Regulation of: - amounts of various constituents in cigarette smoke - information on packages regarding smoke constituents - smokefree tobacco products