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Regulation of:  - amounts of various constituents    in cigarette smoke  - information on packages    regarding smoke constituents - smokefree tobacco products
To be meaningful from health point of view, regulation of smoke constituents should relate,  not to machine yield ,  but to  smokers’ intake,   taking into account the interaction between the smoker and the product.
Jarvis MJ, Boreham R, Primatesta P, Feyerabend C, Bryant A.   N icotine yield from machine-smoked cigarettes and nicotine intakes in smokers: evidence from a representative population survey. J Natl Cancer Inst. 2001 Jan 17;93(2):134-8 .
 
 
 
In I 2001, the U.S. National Cancer Institute (NCI) published Monograph 13
Monograph 13 concluded:  “Measurements of tar and nicotine yields using the FTC method do not offer smokers meaningful information on the amount of tar and nicotine they will receive from a cigarette.” ,[object Object]
But,   there is no such thing as  ” the (one and only) way smokers actually consume cigarettes”   because: ,[object Object],[object Object]
What is it that determines an individual smoker’s intake ? ,[object Object],[object Object]
A smoker’s intake of substance A  =    machine yield of A  (his nicotine intake)  ×    machine yield of nicotine   Amount of nicotine  RATIO   substance A / nicotine   determined by   determined by     the smoker  cigarette   properties
 
Example of brand comparison
Example of rule in an  ”intake-related” regulation of cigarette smoke constituents . T/N ratio <10  (and, optionally  Machine yield of tar <12 mg Machine yield of nicotine <1.4 mg)
Example of brand comparison
Regulation of:  - amounts of various constituents    in cigarette smoke  - information on packages    regarding smoke constituents - smokefree tobacco products
Health-related purpose of consumer info on cigarette packages:   To help the smoker minimize his intake of harmful smoke constituents. Therefore, info should be related to potential INTAKE.  Consequently,  machine yield figures are meaningless.
Machine yield figures on packages are even MISLEADING, since their appearence gives the false impression that: - nicotine intake were determined by   cigarette properties and differing widely    between different brands but independent   of how you smoke. - low figures for a substance, e.g. tar, would    indicate low intake of that substance   i.e. ”This is a mild cigarette”.
Instead, smokers should be aware... - that they are themselves    influencing their intake by the way    they smoke - that the self-determined intake of    nicotine  is about the same from all   cigarettes - that the intake of  other substances     is influenced also by cigarette    properties  (yield ratio to nicotine)
Possible model for a meaningful and truthful info box on packages :   Nicotine delivery from one of these cigarettes   -  to a smoking machine (ISO standard):  0.6 mg    -  to a smoker: 0.1 – 2.0 mg depending on    how it is smoked   Every milligram of nicotine is accompanied by:   Tar:  8 mg  Carbon monoxide: 9 mg
Regulation of:  - amounts of various constituents    in cigarette smoke  - information on packages    regarding smoke constituents - smokefree tobacco products
Mean nitrosamine content of moist snuff products from various sources based on dry weight
 
 
 
 
Summary (1) Regulation of amounts of smoke constituents ,[object Object],[object Object]
Summary (2) Regulation of information on packages ,[object Object],[object Object]
Summary (3) Regulation of smokefree products ,[object Object],[object Object]

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Regulation of tobacco ingredients for largest possible reduction of health risks

  • 1.  
  • 2. Regulation of: - amounts of various constituents in cigarette smoke - information on packages regarding smoke constituents - smokefree tobacco products
  • 3. To be meaningful from health point of view, regulation of smoke constituents should relate, not to machine yield , but to smokers’ intake, taking into account the interaction between the smoker and the product.
  • 4. Jarvis MJ, Boreham R, Primatesta P, Feyerabend C, Bryant A.   N icotine yield from machine-smoked cigarettes and nicotine intakes in smokers: evidence from a representative population survey. J Natl Cancer Inst. 2001 Jan 17;93(2):134-8 .
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  • 8. In I 2001, the U.S. National Cancer Institute (NCI) published Monograph 13
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  • 12. A smoker’s intake of substance A = machine yield of A (his nicotine intake) × machine yield of nicotine Amount of nicotine RATIO substance A / nicotine determined by determined by the smoker cigarette properties
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  • 14. Example of brand comparison
  • 15. Example of rule in an ”intake-related” regulation of cigarette smoke constituents . T/N ratio <10 (and, optionally Machine yield of tar <12 mg Machine yield of nicotine <1.4 mg)
  • 16. Example of brand comparison
  • 17. Regulation of: - amounts of various constituents in cigarette smoke - information on packages regarding smoke constituents - smokefree tobacco products
  • 18. Health-related purpose of consumer info on cigarette packages: To help the smoker minimize his intake of harmful smoke constituents. Therefore, info should be related to potential INTAKE. Consequently, machine yield figures are meaningless.
  • 19. Machine yield figures on packages are even MISLEADING, since their appearence gives the false impression that: - nicotine intake were determined by cigarette properties and differing widely between different brands but independent of how you smoke. - low figures for a substance, e.g. tar, would indicate low intake of that substance i.e. ”This is a mild cigarette”.
  • 20. Instead, smokers should be aware... - that they are themselves influencing their intake by the way they smoke - that the self-determined intake of nicotine is about the same from all cigarettes - that the intake of other substances is influenced also by cigarette properties (yield ratio to nicotine)
  • 21. Possible model for a meaningful and truthful info box on packages : Nicotine delivery from one of these cigarettes - to a smoking machine (ISO standard): 0.6 mg - to a smoker: 0.1 – 2.0 mg depending on how it is smoked Every milligram of nicotine is accompanied by: Tar: 8 mg Carbon monoxide: 9 mg
  • 22. Regulation of: - amounts of various constituents in cigarette smoke - information on packages regarding smoke constituents - smokefree tobacco products
  • 23. Mean nitrosamine content of moist snuff products from various sources based on dry weight
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