The document summarizes key aspects of Chapter 12 from the IPCC's Sixth Assessment Report on Central and South America. It discusses climatic impact drivers, such as heat, cold, wet, dry and wind conditions, and projected changes in these drivers across the region by 2050. Figures are presented on increasing hot days exceeding 35°C and heat index thresholds exceeding 41°C, as well as changes in climatic impact driver indices like heavy precipitation and drought. The chapter examines impacts on sectors like health, water resources, agriculture, ecosystems and more.