2. 2
12 F
Daughter of an anesthetist
Referred for “recurrent abdominal pain” for past 2
years
History mainly given by mother and
when allowed (!) by father; the child
mainly kept fiddling with her “mobile”
On examination:
Medium built,
No anemia, cyanosis, jaundice, lymphnodes
P/A
4. 4
Should we accept the diagnosis of RAP
made elsewhere, or investigate this case
further? Why?
5. 5
Let us see what
different kinds
of abdominal
pains this
young lady
could have……
Acute
Organic
Inorganic/ Idiopathic/
functional
Chronic
Organic
Inorganic/ Idiopathic/
functional
Here again there may be
many variations
6. 6
One has to be careful.
Goo......d history
Attention to body
language
Thorough physical
Meticulous follow-up
7. Pain distant from the
umbilicus
Pain that awakens the
child
Significant vomiting or
diarrhea
Associated fever
7
Organic pain
8. 8
• Family history of
organic diseases
• Involuntary weight
loss, slowed linear
growth, or delayed
puberty
• Systemic
involvement Organic pain
9. Localized fullness
or mass effect
Organomegaly
Localized
tenderness
Perianal
abnormalities
9
Organic pain
12. 12
Functional abdominal pain will have none
of these.
Different types of idiopathic/ inorganic
pains
•Recurrent abdominal pain
•Chronic abdominal pain
•Functional abdominal pain
13. Common understanding of Recurrent
abdominal Pain
History of at least three episodes of pain
Pain sufficiently severe to affect activities
Episodes occur over a period of three months
No known organic cause
Hyams et.al 1996.
13
15. 15
Functional abdominal pain
For practical purpose .....
it is a type of pain which affects a particular
GI function but there is no organic cause
that could be found.
16. 16
So.. Functional pain could be..
Functional dyspepsia (Rome III criteria, 2006)
•Epigastric Localization
•Persistent or recurrent
•Associated with eating;
•Nausea, vomiting, heartburn, oral
regurgitation,
•Early satiety, excessive hiccups and
belching.
No evidence of underlying organic problem
17. Functional Abdominal Pain
Irritable bowel syndrome
Functional abdominal pain associated
with alteration in bowel movements
Symptoms of altered bowel pattern
include:
diarrhea, constipation, or a sense of
incomplete evacuation.
17
19. 19
Functional abdominal pain syndrome
•Functional abdominal pain without
the characteristics of dyspepsia,
irritable bowel syndrome, or
abdominal migraine.
• Have at least 25% of the time one or
more of the following.
• Some loss of daily function.
• Additional somatic symptoms such as
headache, limb pain, or difficulty
sleeping
20. •"recurrent abdominal pain"
should not be used as a
synonym for functional,
psychological, or stress-
related abdominal pain .
American Academy of Paed.2005
20
22. EPIDEMIOLOGY
Chronic abdominal pain affecting 9-15% of
children.
13% of middle school and 17% of high
school children have weekly complaints
of abdominal pain.
In a study of 1,000 school-age children,
RAP affected males & females equally up
to 9 yrs. of age, the incidence in females
increased such that between 9 & 12 yrs.,
the female-to-male ratio was 1.5:1.
22
23. EVALUATION
AAP and NASPGHAN guidelines:
History, physical examination, and stool
testing for occult blood to identify
potential indications of an organic
etiology.
Thorough physical examination
.....” USG, endoscopy, or esophageal pH
monitoring not helpful in the absence of
"alarm findings”.
23
24. Management of functional abdominal
pains
Reassurance and education of the child
and family.
Symptomatic treatment.
24
25. Outcome
After 5 years,
1/3 of children with RAP will have
resolution of their pain,
1/3 continue to complain of the same
symptoms, and
1/3 will have a different recurrent pain
complaint.
25
26. 26
Coming back to our case..
Since the pain was located in epigastrium
Vomiting, and with
Epigastric tenderness
This was taken as a case of APD.
Dietary history was remarkable.
For past three months, she had
eaten only and only junk food!
Diet was changed,
PPI were given, and
The patient counselled
Now she is free from here all complaints.
27. 27
Summary
Of various types of abdominal pains, a large
minority have pain without identifiable cause or
significant consequences.
To sit on them, you must satisfy yourself by way
of meticulous history, physical and follow-up
Detailed investigations are not necessary for
these “functional pain”
30. SUMMARY AND CONCLUSIONS
Chronic abdominal pain is defined by pain of at least
three months' duration, although some clinicians
consider pain of more than one to two months'
duration to be chronic.
Recurrent abdominal pain is defined by more than
three episodes of pain that are sufficiently severe to
affect activity and that occur over the course of at
least three months.
30
Editor's Notes
If you see a child like this, by her body language you surmise that she can’t be harboring serious illness.
The look is quite characteristic, worried patient looks worried and the child may also look sick. Dismayed patient has the appearance of questioning, as to…..”after all what is going on doc. You read big books…but can’t find out why my child has recurrent pain..”
My suggestion to you is you never accept anything anyone has said. It should make sense to you. Otherwise question anything and everything if it defies your logic. This child has pain localized in epigastrium and that is why we will not accept the diagnosis of RAP. Investigations does not necessarily mean tests, but further inquiries and if required tests to find a specific cause which when treated will give relief from pain.
Let us consider different types of pain a pediatric or adolescent could have.
Acute pain by definition is of shorter duration, few hours to a day or so. There is a sub-type of this what we call “abrupt” pain; one minute everything is fine and next patient in agony. This abrupt pain could be because of perforation or mesenteric embolization or torsion. Chronic pain is one which has much longer duration, says months or years.
Some acute pains are recurrent so one may call it chronic and some chronic pain have acute exacerbations. So while evaluating any pain these things needs keeping in mind.
Acute and chronic are differentiated by definition most of the time. It is more important to differentiate between organic and functional pain. Once you have diagnosed functional pain, follow-up is mandatory. It is during the follow-up that you reassess your diagnosis and look for any slip ups.
Organic pain has altogether different look about it; the child and thier care takers both look unwell
These investigations, if abnormal, will tell you that something is wrong and further probing is needed
Various terminologies used here is confusing enough. There is lot of overlap, so for simplicity we will take for granted that all types of pain mentioned are chronic anyway therefore we take out “chronic pain” category here.
Some argue that “three” episodes may not be necessary.
This pain usually is around tummy button, can come on suddenly and may disappear equally suddenly after a variable period. It may come with any frequency and for any length of time. Apart from pain, obviously there are no other features.
Another category is “functional abdominal pain”.
Of course evidence or no evidence of organic pain depends upon how good is your history and physical examnation.
Another variety related to intestines is called IBS
This entity is vehemently denied by gastroenterology community
A sub-category of functional abdominal pain is “functional abdominal pain syndrome”. Here apart from pain in abdomen, there are many systemic symptoms
Recurrent abdominal pain is a category in itself and not synonymous with functional abdominal pain
- The overall incidence appears to peak @ 10 to 12 years. RAP is rare among children younger than 5 years of age, & an organic cause must be -considered even more carefully in this younger age group.
- Apley observed that males and females are affected equally in early childhood up until the age of 9.
- Between 9 and 12 years of age the female-to-male ratio approaches 1.5 to 1.
- Onset of chronic pain in a child younger than 4 years old requires a more in-depth organic evaluation, particularly for structural abnormalities.
Again need for investigations depend upon how good is your history and physical examination. Having said that parenteral pressure sometimes is so overbearing that you may end up doing blood tests and stool tests and USG. Or even worse, parents themselves get USG done before coming to us!
Management of organic pain will of course be correction of underlying condition.
Factors that seem to be related to worse prognosis are:
positive family history of abdominal symptoms
male sex
age of onset younger than 3 years
a period of more than 6 months before seeking treatment
low educational level and family poverty
One important question here is that is it appropriate to consider this as functional pain? We think not. Because even if there are no structural changes on endoscopy, still patient could have acid-peptic disease. So for us this is a straight forward case of APD.
With the exception of the gallbladder and ascending and descending colon, most digestive tract pain is perceived in the midline
Pain that clearly is lateralized most likely arises from the ipsilateral kidney, ureter, ovary, or somatically innervated structures.
Visceral pain is perceived in the spinal segment at which the visceral afferent nerves enter the spinal cord.