QualiPSo is a four-year project, co-funded by the EU Commission, whose objective is to foster and promote the adoption of Open Source in Industries, SMES, and Public administrations by means of new software, methods, mortars and bricks. In particular, the objective will be achieved by means of different research activities, ranging from the legal issues to the definition of quality measurements mechanisms, all integrated into next generation Factories. These results will be then used within QualiPSo Competence Centre, widespread all over the world.