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Dietary protein at
breakfast in
enhancing satiety
and reducing energy
intake at lunch in
overweight
premenopausal
women
Menopause
Menopause and weight gain tend to go hand in hand,
because of low estrogen production, slower metabolism, and
poor diet and lack of exercise
Decrease in hormone production of estrogen and
progesterone by the Ovaries
No vaginal bleeding for a year
A Natural change
Menopause
Pre Menopause
Post Menopause
3 Stages
Symptoms
Hot Flashes
Back Pain
Night
Sweats
Vaginal
Dryness
Insomnia
Joint
Stiffness
Heart
Palpitations
www.flaticon.com
Osteoporosis
Diabetes
CVD
Urinary Problems
Obesity
Risk
www.flaticon.com
Dietary Modifications
http://www.eatthis.com/menopause
Vitamin D Protein
Calcium
Fluids
Vegetables
Omega 3
Egg Nutrients
Dietary Iron
www.flaticon.com
What Is Protein?
Macromolecules
One or more long chain amino acid residues
Joined by peptide linkages
Breakfast
A breakfast high in protein helps curb hunger throughout the
day
Breakfast high in protein can help promote greater weight
loss than a carbohydrate-based breakfast that contains the
same number of calories
Breakfast = better diet quality and greater
nutrient intake
http://www.aeb.org/images/PDFs/FoodManufacturers/AEB_WP_Protein.pdf
Fallaize R, Wilson L, Gray J, Morgan LM, Griffin BA. Variation in the effects of three different breakfast meals on subjective
satiety and subsequent intake of energy at lunch and evening meal. Eur J Nutr. 2013;52:1353–9
https://www.ncbi.nlm.nih.gov/pubmed/25686619
Satiety and hunger management are key components to
control weight
Protein increases and maintains weight loss
resulting from appetite regulations and energy
expenditure
Appetitive and Metabolic effects of
Sausage and egg based
convenience breakfast meals in
overweight premenopausal women
Nutrition Journal (2015) 14:17
DOI 10.1186/s12937-015-0002-7
Authors-Tia M Rains, Heather J Leidy, Kristen D Sanoshy, Andrea L Lawless and Kevin C Maki
1
Biofortis Clinical
Research
Published on
10/2/2105
Aim
To evaluate the effects of consuming two higher-protein
breakfast meals, compared with a lower-protein, higher
carbohydrate breakfast meal and breakfast skipping, on
appetite ratings, postprandial glycemic and insulinemic
responses, and ad libitum energy intake at a lunch meal in
overweight, premenopausal women
2
3
1 screening visit 4 test visits
separated by at least 5 days
N=34
Test visits were scheduled during the
follicular phase of each woman’s
menstrual cycle
Participants
Regular consumers of breakfast and
lunch (≥5 days/week)were recruited to
participate
18-55 Year old old Premenopausal
Women
3
Inclusion
Body mass index (BMI) 18.5
to 29.9 kg/m2
Regular consumers of
breakfast and lunch (≥5
days/week)
Exclusion
Self-defined smokers
Weight change of ±2.7 kg
History of cardiac, renal, hepatic,
endocrine, pulmonary, biliary,
pancreatic, GI or neurologic
disorders or cancer (in the last 2
years)
3
Avoidance of vigorous physical activity
No Consumption of alcoholic beverages
And maintenance of habitual caffeine intake within 24 hours
of each test visit
Study Instructions
To replicate the same food and beverage intakes in the Food
record made, prior to their first test visit
4
Procedures
Overnight fast (10–12 hour)
Collection of venous blood
t = −60 min- water, a caffeinated, non-caloric cola, caffeinated coffee, or
tea with non-caloric sweetener
t = −12 Study products given with 175 g of water or water only
Actual water intake was recorded
Visual Analog Scale (VAS) ratings for appetite sensations were
completed prior to study product intake (t = −25 and −15 min) and at 30
min intervals until 240 min.
4
Visual Analog Scale (VAS) ratings
4
Test Products
Two commercially-prepared, frozen
breakfast meals at two different protein levels [30 g
and 39 g/serving]
A low protein (LP) meal
No breakfast
4
Egg white
Poultry
Sausage
Cheese
Potatoes
Syrup
Mini
Pancakes
Butter
4
Water
4
30g 39g
Energy(Kcal)
Carbohydrate(g)
Protein(g)
Total Fat(g)
Fiber(g)
Palatability(au)
2
0
0
0
0
0
-
288
3
44
11
1
7
280
30
13
12
0
7
294
39
13
14
0
6
Test Meal
Features
Palatability was assessed by a 9-point scale with 1 = “dislike extremely” and 9 = “like extremely.”
4
Tortellini Sauce
Ad libitum Lunch was provided
(According to pleasure)
4
Statistical Analysis
5
-30 0 60 120 180 240
Time
(min)
Test Product Consumption
(t = -12 min)
Ad libitum Lunch
= VAS Rating
5
NB 30g PLP 39g P
0
5000
10000
-5000
15000
Fullness in AUC(mm x min) p < 0.001 for all
5
NB 30g PLP 39g P
Hunger in AUC(mm x min) p < 0.01 for all
0
-10000
-5000
5000
5
120
110
100
90
80
70
60
-25 0 30 60 90 120 150 180 210 240
Time (min)
Glucose(mg/dl.)
NB LP 30g P 39g P
5
(p < 0.001)
5
39 g protein condition led to a smaller postprandial change
in glucose (p < 0.05) compared to the NB condition
30 g protein condition led to a smaller postprandial glucose
change (p < 0.001) vs. the LP condition
NB
96 ± 1 mg/dl
LP
112 ± 3 mg/dl
30 g P
101 ± 2 mg/dl
39 g P
96 ± 1 mg/dl
45
40
35
30
25
20
15
10
5
-25 0 30 60 90 120 150 180 210 240
Time (min)
Insulin(pg/ml)
NB LP 30g P 39g P
5
5
30 g and 39 g protein conditions led to lower insulin AUC (p <
0.05 for both) vs. the LP
NB
7 ± 1 pg/mL;
LP
37 ± 3 pg/mL
30 g P
20 ± 2 pg/mL
39 g P
16±2 pg/mL
p < 0.001 for all
NB 30g PLP 39g P
0
600
1000
800
1200
5
Lunch energy intake following each condition (t = 240 min)
(p < 0.05, note - energy intake at lunch for the 30 g Pro breakfast vs. LP breakfast p = 0.053)
Pairwise comparisons between conditions were conducted using Tukey’s adjustment for multiple
comparisons
400
200
Lunch(Kcal)
692 kcal
789 LP and 810 kcal NB
NB LP
30g P 39g P
+15% Reduction in Energy Intake
p<0.03
5
6
Discussion
Consumption of protein-rich convenience breakfast meals led to reductions in
perceived hunger, increased satiety, and reductions in postprandial glucose and insulin
excursions compared to a low-protein meal in normal to overweight, premenopausal
women
Reduced energy intake at the ad libitum lunch meal, although results only reached
significance for the 39 g protein meal
Two levels of protein served
Both protein levels were sufficient to elicit a greater satiety response and to
reduce postprandial glycemic and insulinemic excursions
Conclusion
7
The results of the present investigation suggest that
sausage/egg convenience meals produce-
greater appetite control
reduce postprandial glycemic and insulinemic
Responses
lowers energy intake at lunch
Conclusion
7
The results of the present investigation suggest that
sausage/egg convenience meals produce-
greater appetite control
reduce postprandial glycemic and insulinemic
Responses
lowers energy intake at lunch
References
8
http://www.todaysdietitian.com/pdf/courses/WellandHighProtein.pdf
http://users.atw.hu/blp6/BLP6/HTML/C0299780323045827.htm
https://www.ncbi.nlm.nih.gov/pubmed/25686619
http://www.aeb.org/images/PDFs/FoodManufacturers/AEB_WP_Protein.pdf
Topic
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334852/
https://www.womens-health-concern.org/help-and-advice/factsheets/focus-series/diet-
nutrition-menopause/
http://www.atlastnaturals.com/pages/Risk-Factors-of-Menopause.html
www.flaticon.com
Icons from-
Protein helps in weight loss

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