This document provides a user guide for the Primal Pictures Human Anatomy Systemic Edition 3D anatomy software. It outlines how to navigate between the 27 chapters organized within 15 sections on the home page. It describes how to view and control 3D models within chapters, view accompanying text for highlighted structures, and use chapter quizzes. It also explains how to search by keyword, browse indexes and contents, print/save images, and access a video tutorial.