The appendix is a vestigial organ attached to the cecum. It varies in length from 7.5-10cm and is lined with colonic mucosa. The blood supply comes from the appendicular artery, a branch of the ileocolic artery. Appendicitis occurs due to obstruction of the appendix leading to bacterial overgrowth and inflammation. The most common presentation is migratory periumbilical pain that increases in the right lower quadrant with rebound tenderness. A CT scan can confirm the diagnosis but it is usually diagnosed clinically using Mantrel's criteria. Treatment involves antibiotics and bowel rest or an appendectomy if surgery is required.