The Child Brain Foundation aims to establish the first international research foundation focused on child neurosciences. It will consolidate current expertise at Hopital Robert Debre, one of the largest children's hospitals in France, and explore new areas of neuroscience research. The Foundation will fund a range of research activities, from basic to clinical studies, focusing on protection and development of the child's brain. It will take an innovative approach through the use of technologies like tablets, social networks, and a collaborative platform to share knowledge between medical professionals, families, and partners. The goal is to transform child healthcare by preventing and curing neurological diseases while also connecting medical care to educational development.

1. CHILD BRAIN FOUNDATION CHILDREN HOSPITAL ROBERT DEBRÉ, ASSISTANCE PUBLIQUE DE PARIS Professor Philippe EVRARD, Doctor Gérard NGUYEN Co-Founders

2. Introduction Robert Debré University Hospital - Assistance Publique Hôpitaux de Paris -, one of the biggest Children Hospital in France (83000 emergencies per year, 40 000 stays, 3000 births, 500 beds, target population of 2 Mio ). Its medical expertise focused on the child and the mother with significant research on childhood deseases . Neurosciences is one of the International Excellence Childcare and research organisation. The research Unit directed by Prof Pierre Gressens focuses on Neuroprotection of the child brain. Lots of Research Foundations develop projects on the file of Adult Neurosciences, but only very structures are on the filed of Child Brain

4. 2. Our Ambition Our ambition is to set up the first International Research Foundation on Child Neurosciences from Fundamental research to translational clinical research including child neurodevelopmental disabilities Our ambition is to set up the first International Research Foundation on Child Neurosciences : from Fundamental research to translational clinical research including child neurodevelopmental disabilities --------------- The benefits will be to transform the child hospitalisation by: 1. preventing/ curing child neurodevelopment deseases 2. creating therapeutica-educational exchange platform 3. defining new economic business model for healthcare

5. 3. Role of the Child Brain Foundation Our ambition is to set up the first International Research Foundation on Child Neurosciences from Fundamental research to translational clinical research including child neurodevelopmental disabilities Define, fund and promote Research activities, in the field of protection and repair of the brain of the child, because of its special vulnerability and its potential for plasticity. These research activities of normal and pathological development of the child's brain will be conducted with reference to fundamental studies in animals and humans, clinical or epidemiological, outcomes and medico-social and educational research They will be part of a cooperative research and multidisciplinary responding to the child-family centered approach. Family and parents associations will be an active partner.

7. ICE 4. How will be the framework ? It will ensure a collaborative 2.0 approach of all professionnals – medical, educational, patients/families involved and partners the Foundation acts as a facilitator between government, industry and private partners. In this perspective, it will ensure that research subjects do not overlap with those implemented or planned in other organisms

8. 4. What will it deliver ? Fund activities to disseminate research results and information campaigns Developing with corporations, private or public, all cooperation and initiatives within the corporate purpose of the Foundation Finance research papers or publications prizes or awards, holding conference and conducting training to ensure optimum effectiveness of its action, Finance tendering programs neuroscience research and prevention of childhood disability, Finance research programs on child and family outcomes and on ICT projects in the field of child neurodevelopmental issues

10. 5 . To summarize: Moving into the future of child care Our ambition is to set up the first International Research Foundation on Child Neurosciences from Fundamental research to translational clinical research including child neurodevelopmental disabilities The child Brain Foundation is a key innovative initiative Connected to the biggest Neuro-Child Hospital in France Hopital Robert Debre- APHP Consolidating all current child Neurosciences expertises and exploring new Neurosciences fields of investigation Going beyong traditionnal medical research = > by using ICT technologies (tablettes, visual, audio, data mining, social network) => by using a 2.0 collaborative platform to gather observations, results and share knowledge => by connecting medical–care to educational – learning development

11. Professor Philippe EVRARD mail : philippe.evrard@rdb.aphp.fr Doctor Gérard NGUYEN mail : [email_address] Hôpital Robert-Debré (Assistance Publique - Hôpitaux de Paris) Thank you