This document summarizes a research paper that evaluated the use of micro-scale thermogravimetric analysis (μ-TGA) to determine nanoparticle surface coatings and purity. The μ-TGA technique allows analysis of small samples with high detection limits and is less time consuming than conventional TGA. Experimental results showed that μ-TGA can distinguish coating layers on nanoparticles and measure coating composition, agreeing with conventional TGA. μ-TGA also analyzed the purity of carbon nanotube and metal nanoparticle samples. The study demonstrates that μ-TGA is a reliable technique for nanoparticle surface and composition characterization using only small sample sizes.

1. Determination of Nanoparticle Surface Coatings and Nanoparticle
Purity Using Micro scale Thermo-gravimetric Analysis
Author’s Name : Elisabeth Mansfield, Katherine M. Tyner,
Christopher M. Poling, and Jenifer L. Blacklock
Name of the Journal : Analytical Chemistry
Volume-86, pages : 1478—1484, published year-2014
Presented by:
Md. Amzad hossain
M.Sc. Student
Roll-0417032702
Course Coordinator:
Dr. Md. Shafiul Azam
Assistant Professor

2. Why I have chosen this paper ?

3. • Small samples are needed for analysis
• High detection limit (less than nanogram)
• Less time consuming technique
• Reliable technique
Motivation

4. E
Experimental Section

5. Experimental Section
where A =the active area
ρq = the density of quartz
μq = the shear modulus of quartz
𝑓̥(MHz) = the resonant frequency of the
QCM, and
Δ𝑓 (Hz) = the frequency shift
correlating to the change in mass,Δm.
Sauerbrey equation

6. Results and Discussion
Figure . Mass percent versus temperature thermograms for μ-TGA (red) and conven-
tional TGA instruments (blue). (A) NIST SRM 2483 single-wall carbon nanotube soot
and (B) a high metal content nanoparticle sample.

7. Results and Discussion
Figure 2. (A) Mass % versus temperature thermogram of SiO2−PEG(n = 25) nanoparticle
samples evaluated using μ-TGA (red) as compared to a conventional TGA measure-
ment(blue). (B) Mass %versus temperature thermogram of SiO2(n = 8) nano-particle
samples evaluated using μ-TGA (red) as compared to a conventional TGA
measurement(blue).

8. Table-1 : Average Mass Percent for Twenty-Five SiO₂-PEG Nanoparticles
Samples
Temperature
20 100 200 250 300 400 500
Average 100 100.427 95.8517 88.3802 77.0359 63.7344 65.859
SD 0 1.00103 2.69323 1.59153 4.08187 2.27163 2.92982
%RSD 0 0.99677 2.81038 1.80077 5.29866 3.56421 4.44862
Results and Discussion

9. Results and Discussion
Figure 3. (A) μ-TGA mass % versus temperature thermograms of four layer-by-layer
coated Au nanoparticle samples. (B) DLS results for particle intensity versus diameter
for four layer-by-layer Au nanoparticle samples. In both, 30nm Au NPs + PLL (black),
30 nm Au NPs + PLL + DNA (red), 30 nm Au NPs + PLL + DNA + PLL (blue), and 30
nm Au NPs + PLL + DNA + PLL + DNA (green).

10. DNA content
(ng/μL)
Size(nm)mass percent
remaining (%)
Table 2. Mass Percent Remaining after Decomposition of All Layers, Size, and DNA
Content for Layer-by-Layer Coated Gold Nanoparticles
Results and Discussion
Coated Gold
Nanoparticles
Temperature
400˚C

11. • Simple technique for characterization of
nanoparticle
• No others techniques are needed here
• Did not clear in which particular case it can
determine purity as well as composition
My Opinion