This document discusses microorganisms that can cause foodborne illness, known as pathogens. It identifies the main types of pathogens as viruses, bacteria, parasites, and fungi. Viruses are the leading cause of foodborne illness. Bacteria usually grow between 41-135°F, so keeping food out of this temperature danger zone is key to control. Parasites must live in other animals. Fungi sometimes make people sick or spoil food. Pathogens need food, proper acidity, temperature, time, oxygen, and moisture to grow. Controlling these factors (FAT TOM) is important to prevent illness. Certain fish and shellfish can contain natural toxins from what they eat.