This document discusses the formulation, production, packaging, and sterilization of parenteral products. It covers various parenteral dosage forms including solutions, suspensions, emulsions, and dry powders. Production methods like sterile filtering, freeze-drying, spray drying and aseptic crystallization are described. Considerations for packaging, sterility validation, and ensuring quality are also summarized.
This document discusses pharmaceutical emulsions. It defines an emulsion as consisting of two immiscible liquids, one dispersed as droplets in the other. Emulsions are stabilized by emulsifying agents. Pharmaceutical applications of emulsions include oral, rectal, topical, and intramuscular administration. Different types of emulsions like O/W and W/O are described. Factors affecting emulsion stability and types of instabilities are outlined. Methods for emulsification, preservation, and packaging are also summarized.
This document discusses parenteral suspensions and emulsions. It covers formulation considerations like choice of excipients, manufacturing methods, and evaluation. Suspensions require stabilization to prevent settling and caking. Emulsions are oil-water or water-oil dispersions used for total parenteral nutrition. Both require sterilization and maintenance of physical and chemical stability over shelf life.
Ophthalmic products are specialized dosage forms designed for administration to or around the eye. Common types include eye drops, ointments, gels and contact lens solutions. Plastic bottles made of materials like LDPE are widely used for packaging as they are easy to use and reduce spillage compared to older glass bottles. Parenteral products must be exceptionally pure and free from contamination due to direct injection. Common containers include glass vials, syringes and plastic bags or bottles. Rubber stoppers and seals are often used for closures. Proper packaging and container selection is important to prevent issues like permeation, leaching or sorption which could impact drug stability or purity. A variety of tests exist to check package
Emulsion ppt prepared by yasir yaqoob !!! Lahore School of Pharmacy, PakistanMuhammad Yasir
The document provides an overview of emulsions, including:
- Definitions of emulsions and the internal/external phases
- Types of emulsions such as oil-in-water and water-in-oil
- Advantages and disadvantages of emulsions
- Tests to identify emulsion types
- Emulsifying agents and theories of emulsification
- Methods for preparing emulsions such as dry gum and wet gum methods
The document discusses emulsions, which are mixtures of two or more liquids that do not normally mix. It defines the key types of emulsions as oil-in-water (O/W), water-in-oil (W/O), and multiple emulsions. It also explains the differences between O/W and W/O emulsions and describes detection tests that can identify the emulsion type. Finally, it provides examples of common emulsifying agents like lecithin, soap, and gum and discusses their properties and uses in emulsions.
Las emulsiones son dispersiones de un líquido en otro líquido inmiscible. Constan de dos fases, una interna dispersa y otra externa continua. Los componentes principales son la fase acuosa, la fase oleosa y el emulsificante. Las emulsiones pueden ser de tipo aceite en agua (O/W) o agua en aceite (W/O), y en ocasiones múltiples (W/O/W u O/W/O). La elección del tipo depende de la vía de administración. Los emulsificantes forman una película alre
Emulsions are suspensions of small liquid droplets of one liquid dispersed in another liquid in which it is not soluble. They are classified based on the dispersed and continuous phases as oil-in-water (O/W) or water-in-oil (W/O) emulsions. Emulsions are kinetically stable systems due to the presence of emulsifying agents such as surfactants that form protective interfacial films around droplets and prevent coalescence. The type of emulsion formed depends on the hydrophilic-lipophilic balance (HLB) of the surfactant based on Bancroft's rule, with more water-soluble surfactants producing O/W emulsions
This document discusses the formulation, production, packaging, and sterilization of parenteral products. It covers various parenteral dosage forms including solutions, suspensions, emulsions, and dry powders. Production methods like sterile filtering, freeze-drying, spray drying and aseptic crystallization are described. Considerations for packaging, sterility validation, and ensuring quality are also summarized.
This document discusses pharmaceutical emulsions. It defines an emulsion as consisting of two immiscible liquids, one dispersed as droplets in the other. Emulsions are stabilized by emulsifying agents. Pharmaceutical applications of emulsions include oral, rectal, topical, and intramuscular administration. Different types of emulsions like O/W and W/O are described. Factors affecting emulsion stability and types of instabilities are outlined. Methods for emulsification, preservation, and packaging are also summarized.
This document discusses parenteral suspensions and emulsions. It covers formulation considerations like choice of excipients, manufacturing methods, and evaluation. Suspensions require stabilization to prevent settling and caking. Emulsions are oil-water or water-oil dispersions used for total parenteral nutrition. Both require sterilization and maintenance of physical and chemical stability over shelf life.
Ophthalmic products are specialized dosage forms designed for administration to or around the eye. Common types include eye drops, ointments, gels and contact lens solutions. Plastic bottles made of materials like LDPE are widely used for packaging as they are easy to use and reduce spillage compared to older glass bottles. Parenteral products must be exceptionally pure and free from contamination due to direct injection. Common containers include glass vials, syringes and plastic bags or bottles. Rubber stoppers and seals are often used for closures. Proper packaging and container selection is important to prevent issues like permeation, leaching or sorption which could impact drug stability or purity. A variety of tests exist to check package
Emulsion ppt prepared by yasir yaqoob !!! Lahore School of Pharmacy, PakistanMuhammad Yasir
The document provides an overview of emulsions, including:
- Definitions of emulsions and the internal/external phases
- Types of emulsions such as oil-in-water and water-in-oil
- Advantages and disadvantages of emulsions
- Tests to identify emulsion types
- Emulsifying agents and theories of emulsification
- Methods for preparing emulsions such as dry gum and wet gum methods
The document discusses emulsions, which are mixtures of two or more liquids that do not normally mix. It defines the key types of emulsions as oil-in-water (O/W), water-in-oil (W/O), and multiple emulsions. It also explains the differences between O/W and W/O emulsions and describes detection tests that can identify the emulsion type. Finally, it provides examples of common emulsifying agents like lecithin, soap, and gum and discusses their properties and uses in emulsions.
Las emulsiones son dispersiones de un líquido en otro líquido inmiscible. Constan de dos fases, una interna dispersa y otra externa continua. Los componentes principales son la fase acuosa, la fase oleosa y el emulsificante. Las emulsiones pueden ser de tipo aceite en agua (O/W) o agua en aceite (W/O), y en ocasiones múltiples (W/O/W u O/W/O). La elección del tipo depende de la vía de administración. Los emulsificantes forman una película alre
Emulsions are suspensions of small liquid droplets of one liquid dispersed in another liquid in which it is not soluble. They are classified based on the dispersed and continuous phases as oil-in-water (O/W) or water-in-oil (W/O) emulsions. Emulsions are kinetically stable systems due to the presence of emulsifying agents such as surfactants that form protective interfacial films around droplets and prevent coalescence. The type of emulsion formed depends on the hydrophilic-lipophilic balance (HLB) of the surfactant based on Bancroft's rule, with more water-soluble surfactants producing O/W emulsions
Drug dosage forms can be liquid, solid, or semisolid. Common solid dosage forms include capsules, tablets, and powders. Capsules contain medications inside a gelatin shell while tablets are compressed powders. Powders can be divided into individual doses or bulk. Liquid dosage forms include solutions, suspensions, drops, emulsions, and injections. Semisolid forms such as ointments, creams, gels, and pastes are applied topically to the skin or mucous membranes.
dosage forms and route of drug administrationAbubakar Fago
The document discusses different dosage forms and routes of drug administration. It describes how drugs are formulated with excipients into various dosage forms for efficacious delivery. The main dosage forms covered are solid forms like powders, granules, tablets, capsules; semi-solid forms like ointments, creams; and liquid forms like syrups, suspensions, emulsions. Each dosage form has unique characteristics depending on factors like physical appearance, how it is administered, and frequency of dosing. Common routes of administration include oral, topical, and injectable forms.
An emulsion is an unstable mixture of two immiscible liquids stabilized by an emulsifying agent. Emulsions have various pharmaceutical applications including oral and topical drug delivery. The type of emulsion (e.g. oil-in-water, water-in-oil) depends on the relative solubility of the emulsifying agent. Emulsions can be prepared using different methods such as the dry gum, wet gum, or bottle methods. Drugs can be incorporated into emulsions during or after emulsion formation.
This document provides an overview of pharmaceutical emulsions. It defines emulsions as dispersions of one liquid in another immiscible liquid, stabilized by an emulsifying agent. The key topics covered include the classification of emulsions as oil-in-water or water-in-oil, theories of emulsification, common emulsifying agents like surfactants and hydrocolloids, and factors affecting the stability of emulsions such as flocculation and creaming. Pharmaceutical applications of emulsions include lotions, creams, and ointments.
This document discusses mechanisms of emulsion instability and strategies for emulsion stabilization. It describes five mechanisms by which emulsions can break down: creaming, sedimentation, flocculation, coalescence, and phase inversion. It also explains the electrostatic and van der Waals forces that affect emulsion stability, including the electrical double layer and DLVO theory. Finally, it outlines various methods to stabilize emulsions, such as using emulsifiers, matching densities, reducing droplet size, modifying viscosity, and testing stability over time.
This ppt is for pharmacology students of MBBS UG&PG and other healthcare persons who needs basic science like BDS, Nursing Ayurveda unani homeopathy etc.
It will provide you a complete journey through the routes of drug administration, with all the basics covered I hope this presentation will make your fundamentals crystal clear.
types and classification of dental implantsDesa Ghanavi
This document discusses types and classifications of dental implants. It describes 5 main classifications: 1) based on implant design, which includes blade, root form, subperiosteal, transosteal, and intramucosal implants; 2) based on attachment mechanism, which includes fibrointegration and osseointegration; 3) based on body design, including cylindrical, threaded, plateau, perforated, solid, and hollow implants; 4) based on surface, such as smooth, machined, textured, and coated surfaces; and 5) based on material, including metallic, ceramic, polymeric, and carbon implants. Key advantages of implants include maintaining bone height/width and improved stability, retention, and esthetics
STATATHON: Unleashing the Power of Statistics in a 48-Hour Knowledge Extravag...sameer shah
"Join us for STATATHON, a dynamic 2-day event dedicated to exploring statistical knowledge and its real-world applications. From theory to practice, participants engage in intensive learning sessions, workshops, and challenges, fostering a deeper understanding of statistical methodologies and their significance in various fields."
The Building Blocks of QuestDB, a Time Series Databasejavier ramirez
Talk Delivered at Valencia Codes Meetup 2024-06.
Traditionally, databases have treated timestamps just as another data type. However, when performing real-time analytics, timestamps should be first class citizens and we need rich time semantics to get the most out of our data. We also need to deal with ever growing datasets while keeping performant, which is as fun as it sounds.
It is no wonder time-series databases are now more popular than ever before. Join me in this session to learn about the internal architecture and building blocks of QuestDB, an open source time-series database designed for speed. We will also review a history of some of the changes we have gone over the past two years to deal with late and unordered data, non-blocking writes, read-replicas, or faster batch ingestion.
Learn SQL from basic queries to Advance queriesmanishkhaire30
Dive into the world of data analysis with our comprehensive guide on mastering SQL! This presentation offers a practical approach to learning SQL, focusing on real-world applications and hands-on practice. Whether you're a beginner or looking to sharpen your skills, this guide provides the tools you need to extract, analyze, and interpret data effectively.
Key Highlights:
Foundations of SQL: Understand the basics of SQL, including data retrieval, filtering, and aggregation.
Advanced Queries: Learn to craft complex queries to uncover deep insights from your data.
Data Trends and Patterns: Discover how to identify and interpret trends and patterns in your datasets.
Practical Examples: Follow step-by-step examples to apply SQL techniques in real-world scenarios.
Actionable Insights: Gain the skills to derive actionable insights that drive informed decision-making.
Join us on this journey to enhance your data analysis capabilities and unlock the full potential of SQL. Perfect for data enthusiasts, analysts, and anyone eager to harness the power of data!
#DataAnalysis #SQL #LearningSQL #DataInsights #DataScience #Analytics
The Ipsos - AI - Monitor 2024 Report.pdfSocial Samosa
According to Ipsos AI Monitor's 2024 report, 65% Indians said that products and services using AI have profoundly changed their daily life in the past 3-5 years.
Drug dosage forms can be liquid, solid, or semisolid. Common solid dosage forms include capsules, tablets, and powders. Capsules contain medications inside a gelatin shell while tablets are compressed powders. Powders can be divided into individual doses or bulk. Liquid dosage forms include solutions, suspensions, drops, emulsions, and injections. Semisolid forms such as ointments, creams, gels, and pastes are applied topically to the skin or mucous membranes.
dosage forms and route of drug administrationAbubakar Fago
The document discusses different dosage forms and routes of drug administration. It describes how drugs are formulated with excipients into various dosage forms for efficacious delivery. The main dosage forms covered are solid forms like powders, granules, tablets, capsules; semi-solid forms like ointments, creams; and liquid forms like syrups, suspensions, emulsions. Each dosage form has unique characteristics depending on factors like physical appearance, how it is administered, and frequency of dosing. Common routes of administration include oral, topical, and injectable forms.
An emulsion is an unstable mixture of two immiscible liquids stabilized by an emulsifying agent. Emulsions have various pharmaceutical applications including oral and topical drug delivery. The type of emulsion (e.g. oil-in-water, water-in-oil) depends on the relative solubility of the emulsifying agent. Emulsions can be prepared using different methods such as the dry gum, wet gum, or bottle methods. Drugs can be incorporated into emulsions during or after emulsion formation.
This document provides an overview of pharmaceutical emulsions. It defines emulsions as dispersions of one liquid in another immiscible liquid, stabilized by an emulsifying agent. The key topics covered include the classification of emulsions as oil-in-water or water-in-oil, theories of emulsification, common emulsifying agents like surfactants and hydrocolloids, and factors affecting the stability of emulsions such as flocculation and creaming. Pharmaceutical applications of emulsions include lotions, creams, and ointments.
This document discusses mechanisms of emulsion instability and strategies for emulsion stabilization. It describes five mechanisms by which emulsions can break down: creaming, sedimentation, flocculation, coalescence, and phase inversion. It also explains the electrostatic and van der Waals forces that affect emulsion stability, including the electrical double layer and DLVO theory. Finally, it outlines various methods to stabilize emulsions, such as using emulsifiers, matching densities, reducing droplet size, modifying viscosity, and testing stability over time.
This ppt is for pharmacology students of MBBS UG&PG and other healthcare persons who needs basic science like BDS, Nursing Ayurveda unani homeopathy etc.
It will provide you a complete journey through the routes of drug administration, with all the basics covered I hope this presentation will make your fundamentals crystal clear.
types and classification of dental implantsDesa Ghanavi
This document discusses types and classifications of dental implants. It describes 5 main classifications: 1) based on implant design, which includes blade, root form, subperiosteal, transosteal, and intramucosal implants; 2) based on attachment mechanism, which includes fibrointegration and osseointegration; 3) based on body design, including cylindrical, threaded, plateau, perforated, solid, and hollow implants; 4) based on surface, such as smooth, machined, textured, and coated surfaces; and 5) based on material, including metallic, ceramic, polymeric, and carbon implants. Key advantages of implants include maintaining bone height/width and improved stability, retention, and esthetics
STATATHON: Unleashing the Power of Statistics in a 48-Hour Knowledge Extravag...sameer shah
"Join us for STATATHON, a dynamic 2-day event dedicated to exploring statistical knowledge and its real-world applications. From theory to practice, participants engage in intensive learning sessions, workshops, and challenges, fostering a deeper understanding of statistical methodologies and their significance in various fields."
The Building Blocks of QuestDB, a Time Series Databasejavier ramirez
Talk Delivered at Valencia Codes Meetup 2024-06.
Traditionally, databases have treated timestamps just as another data type. However, when performing real-time analytics, timestamps should be first class citizens and we need rich time semantics to get the most out of our data. We also need to deal with ever growing datasets while keeping performant, which is as fun as it sounds.
It is no wonder time-series databases are now more popular than ever before. Join me in this session to learn about the internal architecture and building blocks of QuestDB, an open source time-series database designed for speed. We will also review a history of some of the changes we have gone over the past two years to deal with late and unordered data, non-blocking writes, read-replicas, or faster batch ingestion.
Learn SQL from basic queries to Advance queriesmanishkhaire30
Dive into the world of data analysis with our comprehensive guide on mastering SQL! This presentation offers a practical approach to learning SQL, focusing on real-world applications and hands-on practice. Whether you're a beginner or looking to sharpen your skills, this guide provides the tools you need to extract, analyze, and interpret data effectively.
Key Highlights:
Foundations of SQL: Understand the basics of SQL, including data retrieval, filtering, and aggregation.
Advanced Queries: Learn to craft complex queries to uncover deep insights from your data.
Data Trends and Patterns: Discover how to identify and interpret trends and patterns in your datasets.
Practical Examples: Follow step-by-step examples to apply SQL techniques in real-world scenarios.
Actionable Insights: Gain the skills to derive actionable insights that drive informed decision-making.
Join us on this journey to enhance your data analysis capabilities and unlock the full potential of SQL. Perfect for data enthusiasts, analysts, and anyone eager to harness the power of data!
#DataAnalysis #SQL #LearningSQL #DataInsights #DataScience #Analytics
The Ipsos - AI - Monitor 2024 Report.pdfSocial Samosa
According to Ipsos AI Monitor's 2024 report, 65% Indians said that products and services using AI have profoundly changed their daily life in the past 3-5 years.
ViewShift: Hassle-free Dynamic Policy Enforcement for Every Data LakeWalaa Eldin Moustafa
Dynamic policy enforcement is becoming an increasingly important topic in today’s world where data privacy and compliance is a top priority for companies, individuals, and regulators alike. In these slides, we discuss how LinkedIn implements a powerful dynamic policy enforcement engine, called ViewShift, and integrates it within its data lake. We show the query engine architecture and how catalog implementations can automatically route table resolutions to compliance-enforcing SQL views. Such views have a set of very interesting properties: (1) They are auto-generated from declarative data annotations. (2) They respect user-level consent and preferences (3) They are context-aware, encoding a different set of transformations for different use cases (4) They are portable; while the SQL logic is only implemented in one SQL dialect, it is accessible in all engines.
#SQL #Views #Privacy #Compliance #DataLake
Predictably Improve Your B2B Tech Company's Performance by Leveraging DataKiwi Creative
Harness the power of AI-backed reports, benchmarking and data analysis to predict trends and detect anomalies in your marketing efforts.
Peter Caputa, CEO at Databox, reveals how you can discover the strategies and tools to increase your growth rate (and margins!).
From metrics to track to data habits to pick up, enhance your reporting for powerful insights to improve your B2B tech company's marketing.
- - -
This is the webinar recording from the June 2024 HubSpot User Group (HUG) for B2B Technology USA.
Watch the video recording at https://youtu.be/5vjwGfPN9lw
Sign up for future HUG events at https://events.hubspot.com/b2b-technology-usa/
Beyond the Basics of A/B Tests: Highly Innovative Experimentation Tactics You...Aggregage
This webinar will explore cutting-edge, less familiar but powerful experimentation methodologies which address well-known limitations of standard A/B Testing. Designed for data and product leaders, this session aims to inspire the embrace of innovative approaches and provide insights into the frontiers of experimentation!
End-to-end pipeline agility - Berlin Buzzwords 2024Lars Albertsson
We describe how we achieve high change agility in data engineering by eliminating the fear of breaking downstream data pipelines through end-to-end pipeline testing, and by using schema metaprogramming to safely eliminate boilerplate involved in changes that affect whole pipelines.
A quick poll on agility in changing pipelines from end to end indicated a huge span in capabilities. For the question "How long time does it take for all downstream pipelines to be adapted to an upstream change," the median response was 6 months, but some respondents could do it in less than a day. When quantitative data engineering differences between the best and worst are measured, the span is often 100x-1000x, sometimes even more.
A long time ago, we suffered at Spotify from fear of changing pipelines due to not knowing what the impact might be downstream. We made plans for a technical solution to test pipelines end-to-end to mitigate that fear, but the effort failed for cultural reasons. We eventually solved this challenge, but in a different context. In this presentation we will describe how we test full pipelines effectively by manipulating workflow orchestration, which enables us to make changes in pipelines without fear of breaking downstream.
Making schema changes that affect many jobs also involves a lot of toil and boilerplate. Using schema-on-read mitigates some of it, but has drawbacks since it makes it more difficult to detect errors early. We will describe how we have rejected this tradeoff by applying schema metaprogramming, eliminating boilerplate but keeping the protection of static typing, thereby further improving agility to quickly modify data pipelines without fear.