1) The document discusses implementing new technology trials within a large pharmaceutical company and improving the current framework for technology trials. 2) It proposes a new framework that includes improvements like context-driven trial selection, concerted effort across teams, and sharing results. 3) One example of new technology presented is Deep Search 9, a web data extraction service, and how it could provide benefits like customized search and regulatory monitoring capabilities for the pharmaceutical company.

1. Implementation of new technology within a big pharma
company: Finding a way amidst an ever- changing and
data-driven environment
Natalie Pilote / Patent Analyst, Innovative Medicines
Barbara Roggo / Customer Liason Manager, Novartis Knowledge Center
AI-SDV 2020

2. Trial Problematic
Business Use Only2
Current Model
 Trial offer/request
 Short demo/training session (1-2 hours)
 Free trial period (2-3 weeks)
 Testing (quick and dirty)
 Short discussion (colleagues and provider)
Current Framework
 Too many tools / Too little time / Too little money
 Most of the tools we need we already have
 Disconnect between related disciplines

3. Trial Basis
Business Use Only3
Corporate Obligation
 Allow and create the space needed for exploring new technologies
 Early adopters to support change and shape those new emerging
technologies
Three Fundamental Pilars
 Current Unfulfilled Need(s) => Justification of Expense
 Unique and “Must Have” Feature => Competitive Advantage
 Competitive Pricing => License Negotiation

4. New Framework
Business Use Only4
Improvements
Trial selection
Support and funding
Trial Implementation
Documentation and Sharing of Results
Current Framework New Framework
Random Selection Context Driven Selection
Independent Effort Concerted Effort
Short Time Frame Integration Into Work Flows
and Processes
Results Archived Results Shared

5. Deep SEARCH 9 (DS9)
Business Use Only5
Web data extraction services enabling access to information not available elsewhere
 Systematic and automated approach to crawling specific websites and
targeted information
 Data extraction from any type of unstructured sources
 Building a search corpus from multiple data source
 Enhanced data (post-processing)
 Annotation of natural language text sources
 Application of dictionaries and semantic tools
 Customized search platform
 Hosted, supported and maintained (by DS9)
 DS9 Standard Solutions (examples)
 Corporate News Tracker
 Clinical Trials Tracker
 Conference Search

6. Regulatory Intelligence Monitoring
Business Use Only6
Background Project’s objectives
 The identification and processing of regulatory
documents and is done manually.
 A manual workflow is in place for the dissemination
of regulatory documents.
 Achieve efficiency and optimization by utilizing the
tools and applications available from the Novartis
Knowledge Center.
 Deliver a media monitoring product to support the
RI Monitor Service.
 Develop a dedicated module to compliment the
monitoring service and produce an E2E workflow
 Introduce a compliant process for inpections.
Key questions
 Apply IT framework to support the monitoring and
processing of key documents in the existing
Regulatory Intelligence and Regulatory Policy
workflows which are manually operated today.
 The goal is to streamline and achieve operational
efficiency, improved reporting and notification
service.

7. NKC Media Monitoring Service
Business Use Only7
 Monitoring of business-
relevant information
 Content management in
administrative interface
 Data curation based on
customer needs
 Timely delivery in a
customized format
Automated data
collection from
multiple sources
NKC
consultancy/
license
management
Administrative
interface for
content
management
Ability to
upload files,
pdfs, emails
Data curation
manual or
automated
Distribution of
selected data in
customized
format
Analytical
reports/
subscription
management

8. Newsletter Creation - Process
Business Use Only8
Publishing
(Novartis brand compliant)
Content
(published information)
Filtering
(automated/search engine)
Curation
(manual selection)
Review
(Customer)
Clinical
trials
Articles
Patents
Conferen
ces
Regulato
ry
Business
News
Social
Media
Newsletter
Monitoring Specialist
Expert Searches

9. Regulatory Intelligence Monitor Service
Business Use Only9
Central Tool Requirements - scan, filter and communicate RI info
Monitor and
Gather
Regulatory
News
Analyze
Information &
Assess
Impact
Publish Archive
Automated data
collection
• Aggregation of
RSS feeds
• Web scraping
• Content
structured by
Topics
• Add content
manually
• Manual curation
by SMEs
• Region-specific
newsletters
(US, EU..)
• Subscriber
management
• RSS feeds of
Newsletters
• Newsletter
archive
(searchable)
• Article archive
(searchable)

10. Monitoring Health Authority Websites
Business Use Only10
Automated Data Collection
- RSS Feed Technology available for few HA websites
- Web-Crawling of HA websites in Asia, Latin America..

11. Benefits
Business Use Only11
Flexibility in use of publically available sources
Effficient and streamlined end-to-end process
Best practice sharing across companies
Simple customer interface
Partnering and solving challenges together
Pragmatic and time-saving approach

12. 12
Thank you