The capstone project involved designing an improved perfusion pump system for trauma team training using cadavers. The team determined requirements, iteratively designed and tested prototypes, and delivered a final system featuring pressure sensors, a diaphragm pump, and user-friendly control display. The functional system can generate physiologic blood pressures and flow rates to enhance surgical training opportunities.

1. GRADUATE DEPARTMENT OF BIOENGINEERING
University of Illinois at Urbana-Champaign
BioInstrumentation Capstone Summer 2016
Cadaveric Perfusion Pump for Improving Trauma Team Training
Collaboration Sponsors
OSFHealthCare and University of Illinois College of Medicine
Ankush Gakhar B.S. Electrical Engineering
Ryan Migalla B.S. Engineering Physics
William Lupetini Ross B.S. Electrical Engineering
Jessica Su B.S. Material Science and Engineering

2. Accomplishments
Designed logical iteration testing flow
Determined optimal pump for system
Integrated sensors
Created user-friendly display
Improved software adaptability and readability
Consolidated all aspects into one solid design
Fully documented all hardware and software components
Delivered a functional system that is ready for continuous refinements as
the technology evolves.

3. “The senior author has developed and refined the "Live Cadaver" methodology since 2009 for trauma
surgical training. We are recent adopters and have validated this platform. However, we plan to improve
the method with the design of a new pump that will allow for physiologic parameters to be adjusted during
the utilization of this training platform.”
Upper extremity simulation
Lower extremity simulation

4. Improve upon our partner’s artificial perfusion system by
making it safer, streamlined and able to accurately generate
and measure rapid modulations in fluid pressure.

5. Initial Meetings
Determined focus areas
Defined engineering specifications
Iteration 1
Original pump system reproducibility
Research parts
Iteration 2
Add sensors, new pump, protoboard shield
Iteration 2
Process Iteration 1
Iteration 3

6. Final Design
Front View Side View

7. Solution
Honeywell PX3 pressure sensors
Accurate, Durable, Economical
FloJet Diaphragm Pump
Fast modulation, Smooth operation, Safe

8. Solution
Control & Display Improvements
Easy to adjust and obtain information from
Software Improvements
More robust, easier to understand and modify

9. The Sensor of Choice
Honeywell PX3 pressure sensors
Electrical Connector
Pressure Port
Engineering Specification
Response Time < 2ms
Relative Gauge Measures with respect
to atmosphere
Efficient 5 Vdc
3.5 mA max
Fluid
Compatibility
Oils, brake fluids, air,
water, etc.
Durable > 10 million pressure
cycles
Water-proof IP 67

10. Using a pressure loss model the sensor is able to determine the output of the system
accurately without needing to be near the point of insertion
Pressure drop is modeled using:
Bernoulli’s Equation:
The Hagen - Poiseuille Law:
Sudden area change model:
Calibrating Sensors

11. The Pump of Choice
FloJet Diaphragm Pump
Engineering Specification
Max Flow Rate 2.9 gpm, 11.6 lpm
Max Pressure 50 psi
Efficient and
Powerful
12 Vdc
7.5 A @ 50 psi
Cleanable Run dry with air
Portable 2.6 lbs
Vertical draw Self-prime up to 8 ft.● Reservoir
● Accumulator
● Sensor
● Cadaver
Inlet Outlet
Pump Controller
● Microcontroller
● Display

12. Pump Verification
Able to run for long periods of time
Able to create pulsatile flow
Able to replicate three physiological
blood pressures

13. User-Friendly Display
Switch for 4 Pressure Modes
● Healthy
● Hypertension
● Hypotension
● Prime
LEDs represent ON/OFF mode
Display reads
● Heart Rate
● Sensor Pressure
Main Power ON/OFF Switch Heart Rate Knob

14. Creating the Display
Utilized 3-D printer at Carle to create a quick and custom faceplate

15. Robust Software
Maintains 60+ Hz data capture of
motor power and sensor pressures
Live LCD user output plus USB data
output for historic data
Fast autodetection for sensor type plus
transmission line correction
Emergency shutoff due to electrical
fault or system blockage

16. Flexible Software
Calibration mode for pipe and
motor changes
Code checks for improper changes
Ready to support a dual motor
system

17. Future Recommendations
Test with blood mimicking fluid
Test the effect of flow reduction when attaching system to cadaver
Integration of a PC power supply

18. In Summary
Accomplishments
Designed logical iteration testing flow
Determined optimal pump for system
Integrated sensors
Created user-friendly display
Improved software adaptability and readability
Consolidated all aspects into one solid design
Delivered a functional system that is ready to continue being improved