1. Draft Pharma Policy: The Good, The Bad and The Ugly...............................................1
Interview with Sunil Attavar
2. Career Brand Plan: A Career Stepping
Stone..........................................................9
Soham Wagh
3. Succeeding as Country GM at GSK: A Whitepaper..............................................12
Sundar Ramachandran
4. Role of Digital in the Customer Journey ....................................................................21
Salil Kallianpur
5. Executive Function Disorder .................24
Vivek Hattangadi
How Can Pharma Sales Leaders Create A Winning Sales Organisation?Anup Soans
Inside this Issue
1. Interview with Salil Kallianpur – with Anup Soans, Editor – MedicinMan
“There is much work to be done and a unified pharma industry can prove to be a valuable ally to the government.”
2. Patient-centricity: How Pharma Can Move from Intention to Action by Hanno Wolfram
Patient-centricity begins with moving from talking about the patient to talking to the patient
3. The Corporate Halo Effect by Vivek Hattangadi
How a great corporate brand elevates a company’s products in the minds of doctors and patients
4. For a Positive Attitude, Clean Your Mind’s Windows by Asheesh Kumar Patel
A bad attitude is a learned behavior and can be unlearned when we discover it’s source
5. The Three Transformations for Leadership by Srinivasan Athmanathan
Three key professional traits that every successful leader must possess
6. Book Review: Feather in a C.A.P. by Kamalesh Subramanian
A corporate saga with valuable lessons for professionals of all backgrounds
MedicinMan August 2017 - Role of 2nd Line Manager in PharmaAnup Soans
1. Incentivizing a Patient-First Approach in Indian Pharma – interview with Annaswamy Vaidheesh
A conversation with Annaswamy Vaidheesh, Vice President, OPPI, VP, South Asia & Managing Director, India, GSK on GSKs initiatives to meet the demands of Indian pharma in the digital age while putting the patient first
2. The Indian Pharma Brand Story: From Independence to Now by Vivek Hattangadi
Vivek Hattangadi traces the story of Indian pharma branding from Independence till today through his personal and professional experiences
3. The Second-line Manager as Both Actor and Architect by Sunder Ramachandran
Operational effectiveness and strategic alignment are the two KPIs for every successful second-line manager
4. To SWOT or not to SWOT by K. Hariram
Understanding the strategic intent behind SWOT analysis
Is the Modi Govt Aware of the Damage being Inflicted on Modern Healthcare?Anup Soans
In a brilliant editorial, Dr. Sumit Ghosal lays bare the terrible damage being done to modern medicine through policies and actions that will push India backwards. while developed nations will experience the unprecedented benefits of modern healthcare.
“SWOT ANALYSIS OF NEW PHARMACEUTICAL COMPANY”Dharmik Bhatt
Main Objective
To find the Strength, weakness, Opportunities and threat of the company and all new pharmaceutical companies.
To find out the perception and expectation of doctors and retailers towards the new pharmaceutical company.
Sub Objectives
To find out the big player of the market (Tough Competitor).
To find the way for new pharmaceutical company from tough competition.
To create strategy for company with the help of research detail.
To analyze Vadodara market for company.
To create good communication bridge between new company to doctors and retailers, that full feel all require expectation of both.
How Can Pharma Sales Leaders Create A Winning Sales Organisation?Anup Soans
Inside this Issue
1. Interview with Salil Kallianpur – with Anup Soans, Editor – MedicinMan
“There is much work to be done and a unified pharma industry can prove to be a valuable ally to the government.”
2. Patient-centricity: How Pharma Can Move from Intention to Action by Hanno Wolfram
Patient-centricity begins with moving from talking about the patient to talking to the patient
3. The Corporate Halo Effect by Vivek Hattangadi
How a great corporate brand elevates a company’s products in the minds of doctors and patients
4. For a Positive Attitude, Clean Your Mind’s Windows by Asheesh Kumar Patel
A bad attitude is a learned behavior and can be unlearned when we discover it’s source
5. The Three Transformations for Leadership by Srinivasan Athmanathan
Three key professional traits that every successful leader must possess
6. Book Review: Feather in a C.A.P. by Kamalesh Subramanian
A corporate saga with valuable lessons for professionals of all backgrounds
MedicinMan August 2017 - Role of 2nd Line Manager in PharmaAnup Soans
1. Incentivizing a Patient-First Approach in Indian Pharma – interview with Annaswamy Vaidheesh
A conversation with Annaswamy Vaidheesh, Vice President, OPPI, VP, South Asia & Managing Director, India, GSK on GSKs initiatives to meet the demands of Indian pharma in the digital age while putting the patient first
2. The Indian Pharma Brand Story: From Independence to Now by Vivek Hattangadi
Vivek Hattangadi traces the story of Indian pharma branding from Independence till today through his personal and professional experiences
3. The Second-line Manager as Both Actor and Architect by Sunder Ramachandran
Operational effectiveness and strategic alignment are the two KPIs for every successful second-line manager
4. To SWOT or not to SWOT by K. Hariram
Understanding the strategic intent behind SWOT analysis
Is the Modi Govt Aware of the Damage being Inflicted on Modern Healthcare?Anup Soans
In a brilliant editorial, Dr. Sumit Ghosal lays bare the terrible damage being done to modern medicine through policies and actions that will push India backwards. while developed nations will experience the unprecedented benefits of modern healthcare.
“SWOT ANALYSIS OF NEW PHARMACEUTICAL COMPANY”Dharmik Bhatt
Main Objective
To find the Strength, weakness, Opportunities and threat of the company and all new pharmaceutical companies.
To find out the perception and expectation of doctors and retailers towards the new pharmaceutical company.
Sub Objectives
To find out the big player of the market (Tough Competitor).
To find the way for new pharmaceutical company from tough competition.
To create strategy for company with the help of research detail.
To analyze Vadodara market for company.
To create good communication bridge between new company to doctors and retailers, that full feel all require expectation of both.
an assignment on business level strategies and its impact on the performance of an industrial company in bangladesh: a case study on square pharmaceuticals limited
MedicinMan is the first-of-its-kind effort to foster a culture of excellence among the of field sales professionals in Pharma, Medical Devices, Diagnostics, Disposables and Surgicals.
an assignment on business level strategies and its impact on the performance of an industrial company in bangladesh: a case study on square pharmaceuticals limited
MedicinMan is the first-of-its-kind effort to foster a culture of excellence among the of field sales professionals in Pharma, Medical Devices, Diagnostics, Disposables and Surgicals.
5th Biosimilars Congregation 2014
10th September 2014, Kohinoor Continental Hotel, Mumbai, India
“Uniting industry leaders to analyse advanced commercial developments & to identify successful management strategies of Biosimilars”
Evolution of the healthcare industry in India and the potential impact of the...Harshit Jain
2014 looks to be a positive but challenging year for the Indian health care sector; one in which many historic business models and operating processes will no longer suffice amid rising demand, continued cost pressures, lack of or inadequate care facilities, and rapidly evolving market conditions. India, likely will be dominated by the “Modi-care” –Health assurance for all.
New Indian pharma policy and its impact on Pharmaceutical Industry, Benefits to people, Impact on Imports, employment, skill development, marketing practices and impact of policy in ease of doing business.
Writekraft Research and Publications LLP was initially formed, informally, in 2006 by a group of scholars to help fellow students. Gradually, with several dissertations, thesis and assignments receiving acclaim and a good grade, Writekraft was officially founded in 2011 . Since its establishment, Writekraft Research & Publications LLP is Guiding and Mentoring PhD Scholars.
Our Mission
“To provide breakthrough research works to our clients through Perseverant efforts towards creativity and innovation”.
Vision
Writekraft endeavours to be the leading global research and publications company that will fulfil all research needs of our clients. We will achieve this vision through:
Analyzing every customer’s aims, objectives and purpose of research
Using advanced and latest tools and technique of research and analysis
Coordinating and including their own ideas and knowledge
Providing the desired inferences and results of the research
In the past decade, we have successfully assisted students from various universities in India and globally. We at Writekraft Research & Publications LLP head office in Kanpur, India are most trusted and professional Research, Writing, Guidance and Publication Service Provider for PhD. Our services meet all your PhD Admissions, Thesis Preparation and Research Paper Publication needs with highest regards for the quality you prefer.
Our Achievements
NATIONAL AWARD FOR BEST RESEARCH PROJECT (By Hon. President APJ Abdul Kalam)
GOLD MEDAL FOR RESEARCH ON DISABILITY (By Disabled’s Club of India)
NOMINATED FOR BEST MSME AWARDS 2017
5 STAR RATING ON GOOGLE
We have PhD experts from reputed institutions/ organizations like Indian Institute of Technology (IIT), Indian Institute of Management (IIM) and many more apex education institutions in India. Our works are tailored and drafted as per your requirements and are totally unique.
From past years our core advisory members, research team assisted research scholars from various universities from all corners of world.
Writekraft Research and Publications LLP was initially formed, informally, in 2006 by a group of scholars to help fellow students. Gradually, with several dissertations, thesis and assignments receiving acclaim and a good grade, Writekraft was officially founded in 2011 . Since its establishment, Writekraft Research & Publications LLP is Guiding and Mentoring PhD Scholars.
Our Mission
“To provide breakthrough research works to our clients through Perseverant efforts towards creativity and innovation”.
Vision
Writekraft endeavours to be the leading global research and publications company that will fulfil all research needs of our clients. We will achieve this vision through:
Analyzing every customer’s aims, objectives and purpose of research
Using advanced and latest tools and technique of research and analysis
Coordinating and including their own ideas and knowledge
Providing the desired inferences and results of the research
In the past decade, we have successfully assisted students from various universities in India and globally. We at Writekraft Research & Publications LLP head office in Kanpur, India are most trusted and professional Research, Writing, Guidance and Publication Service Provider for PhD. Our services meet all your PhD Admissions, Thesis Preparation and Research Paper Publication needs with highest regards for the quality you prefer.
Our Achievements
NATIONAL AWARD FOR BEST RESEARCH PROJECT (By Hon. President APJ Abdul Kalam)
GOLD MEDAL FOR RESEARCH ON DISABILITY (By Disabled’s Club of India)
NOMINATED FOR BEST MSME AWARDS 2017
5 STAR RATING ON GOOGLE
We have PhD experts from reputed institutions/ organizations like Indian Institute of Technology (IIT), Indian Institute of Management (IIM) and many more apex education institutions in India. Our works are tailored and drafted as per your requirements and are totally unique.
From past years our core advisory members, research team assisted research scholars from various universities from all corners of world
Subjects/Areas We Cover
Management, Commerce, Finance, Marketing, Psychology, Education, Sociology, Mass communications, English Literature, English Language, Law, History, Computer Science & Engineering, Electronics & Communication Engineering, Mechanical Engineering, Civil Engineering, Electrical Engineering, Pharmacy & Healthcare
Writekraft Research and Publications LLP was initially formed, informally, in 2006 by a group of scholars to help fellow students. Gradually, with several dissertations, thesis and assignments receiving acclaim and a good grade, Writekraft was officially founded in 2011 . Since its establishment, Writekraft Research & Publications LLP is Guiding and Mentoring PhD Scholars.
Our Mission
“To provide breakthrough research works to our clients through Perseverant efforts towards creativity and innovation”.
Vision
Writekraft endeavours to be the leading global research and publications company that will fulfil all research needs of our clients. We will achieve this vision through:
• Analyzing every customer’s aims, objectives and purpose of research
• Using advanced and latest tools and technique of research and analysis
• Coordinating and including their own ideas and knowledge
• Providing the desired inferences and results of the research
In the past decade, we have successfully assisted students from various universities in India and globally. We at Writekraft Research & Publications LLP head office in Kanpur, India are most trusted and professional Research, Writing, Guidance and Publication Service Provider for PhD. Our services meet all your PhD Admissions, Thesis Preparation and Research Paper Publication needs with highest regards for the quality you prefer.
Writekraft Research and Publications LLP was initially formed, informally, in 2006 by a group of scholars to help fellow students. Gradually, with several dissertations, thesis and assignments receiving acclaim and a good grade, Writekraft was officially founded in 2011 . Since its establishment, Writekraft Research & Publications LLP is Guiding and Mentoring PhD Scholars.
Writekraft Research & Publications LLP
(Regd. No. AAI-1261)
Mobile: 7753818181, 9838033084
Email: info@writekraft.com
Web: www.writekraft.com
Research Paper Writing
Writekraft Research and Publications LLP was initially formed, informally, in 2006 by a group of scholars to help fellow students. Gradually, with several dissertations, thesis and assignments receiving acclaim and a good grade, Writekraft was officially founded in 2011 . Since its establishment, Writekraft Research & Publications LLP is Guiding and Mentoring PhD Scholars.
Our Mission
“To provide breakthrough research works to our clients through Perseverant efforts towards creativity and innovation”.
Vision
Writekraft endeavours to be the leading global research and publications company that will fulfil all research needs of our clients. We will achieve this vision through:
Analyzing every customer’s aims, objectives and purpose of research
Using advanced and latest tools and technique of research and analysis
Coordinating and including their own ideas and knowledge
Providing the desired inferences and results of the research
In the past decade, we have successfully assisted students from various universities in India and globally. We at Writekraft Research & Publications LLP head office in Kanpur, India are most trusted and professional Research, Writing, Guidance and Publication Service Provider for PhD. Our services meet all your PhD Admissions, Thesis Preparation and Research Paper Publication needs with highest regards for the quality you prefer.
Writekraft Research and Publications LLP was initially formed, informally, in 2006 by a group of scholars to help fellow students. Gradually, with several dissertations, thesis and assignments receiving acclaim and a good grade, Writekraft was officially founded in 2011 . Since its establishment, Writekraft Research & Publications LLP is Guiding and Mentoring PhD Scholars.
0601017 explore market opportunities for new product launchSupa Buoy
Hi Friends
This is supa bouy
I am a mentor, Friend for all Management Aspirants, Any query related to anything in Management, Do write me @ supabuoy@gmail.com.
I will try to assist the best way I can.
Cheers to lyf…!!!
Supa Bouy
May 2015 Edition of BEACON, A Monthly Newsletter by SIMCON.
Inside this issue:
About Us
Our Team
INDUSTRY ANALYSIS : Pharmaceutical Industry
COMPANY ANALYSIS : Sun Pharma
BRAND ANALYSIS : Kellogg's
Concept of the month
Innovative Marketing Practices for Optimization in Selected Pharmaceutical In...iicecollege
Pharmaceutical Industry is regulated by the production, distribution, selling and the marketing of the products or services which directly or indirectly includes medical, diagnostic and healthcare.It is regulated by economical, political and administrative authority to manage at all levels. So, the industry is governed by both the public and private sector. Therefore innovation is done in various pharma stakeholder and is needed in chronic and acute therapeutic segment.
For more details please visit
www.iicecollege.com
Similar to Pharma Policy 2017 - Read it in MedicinMan September 2017 Issue (20)
An Infectious Disease Specialist, Dr Mandar Kubal Speaks to Pharma on How it ...Anup Soans
Key Point from the Q &A with Dr. Mandar Kubal, Mumbai
Telemedicine has become a very useful tool for clinicians to manage their patients.
Given the ever changing contours of Covid19 treatment, doctors have to check daily for online resources.
It would be wonderful if pharma can provide every specialty the latest developments in treating Covid19 with pre existing conditions instead of sending their unvaccinated field force to give brand reminders.
Pharma should seek frontline worker status for Medical Reps and Field Managers as they are critical to maintain the drug supply chain.
Treat the Field Force as an asset and protect them, instead of pushing them onto the field without vaccination.
And many more insights from a clinician at the frontlines of treating Covid19 patients.
Now on MedicinMan YouTube Channel - https://youtu.be/J_p3paeO_eg
Key Challenges Facing Pharma Industry and the Way ForwardAnup Soans
Suresh Subramanian, pharma veteran discusses Key Challenges Facing Pharma Industry and the Way Forward on Saturday, 27th March at 6 PM on https://www.credoweb.in/discussion/630/key-challenges-facing-pharma-industry-and-the-way-forward
MedicinMan CEO Roundtable 2021 is here... Saturday, Feb 27thAnup Soans
Covid-19 has hugely affected the modes of interaction between physicians and pharma Sales Force.
As of February 2021, most pharma companies in India re-started their F2F visits even though most corporate hospitals have restricted access to salesforce
What is keeping most CEOs awake – How to respond to customer expectations and adjust the content and format accordingly.
How to track complexities of implementation of a new model into marketing & sales teams.
Many research reports have indicated that a hybrid (mixed model) that includes face to face and digital interactions are favoured by most respondent Physicians.
The other challenge is the need to change the outdated traditional digital model, which is overused and creates digital noise into an innovative interactive model.
Register Now: https://lnkd.in/gmJK8et
Key Account Management - Time for India Pharma to Adopt KAMAnup Soans
Pharma's 40-year Model of Pitching to the HCPs is Over says Hanno Wolfram author of Key Account Management in Pharma...
Watch the webinar on Digital Excellence Pharma Academy today at 6 PM to know more - https://lnkd.in/gjZRN6q
How can Pharma Use Digital to Engage Doctors and Understand PatientsAnup Soans
Doctors and patients are already using digital for many healthcare needs. Telemedicine is a prime example.
A Webinar by Dr. Shenoy Robinson today at 6 PM on - https://www.credoweb.in/discussion/604/how-can-pharma-use-digital-to-engage-doctors-and-understand-patients
How can Pharma Use Digital to Engage Doctors and Understand Patients
Why Indian Pharma Needs to Enable Managers to Develop TalentAnup Soans
People need the support of their leaders and organisations processes to develop their talents.
Deep Bhandari delves deep into the topic of Talent Development and its impact on individuals and organisations.
Digital Excellence Pharma Academy Certification ProgramAnup Soans
Now on YouTube: Gartner's Top Five Priorities for Pharma Business Leaders and @Hariram K's Key Learning Points on Leadership
25-minute discussion with Deep Bhandari on the Gartner Report and Leadership Imperatives by Hariram Krishnan on How the DEPA Certification Program Can Make Pharma Professionals Future Proof
https://lnkd.in/gHiT_WU via @YouTube
Architecture To Develop Pharma Business Leaders For Today and Tomorrow Anup Soans
4 Factors of Digital Transformation
1. Leadership Mindset for Digital Transformation
2. Digital Transformation - Why and How to Do it Right
3. Sales and Sales Management - Challenges & Solutions
4. Customer/Patient Centricity - Why and How to Do it Right
What is Indian Pharma Thinking about Digital? A Research ProjectAnup Soans
First Ever Indian Pharma Centric Survey: A CredoWeb India – #MedicinMan Research Project
As a part of Digital Excellence Pharma Academy , we initiated a research project with a detailed survey to understand the current status and issues faced by Indian Pharma companies in adopting digital to bridge the pharma – physicians disconnect.
You can know more about the scope and scale of this research project and survey at https://lnkd.in/gR5JMer
Digital Excellence Pharma Academy - Webinar & Online Certification ProgramAnup Soans
Ready for the next Webinar on Digitalisation of Pharma Marketing?
Digital Excellence Pharma Academy a partnership between MedicinMan and CredoWeb not only equips pharma/devices/diagnostics/disposable company employees with KA$H (you’ll learn about KA$H soon in the future webinars), but offers you the ability to adopt the digital platform to communicate and engage your customers and create lasting experiences to build your relationship with customers.
To know more on how to engage doctors via digital, attend 40+ webinars brought to you by CredoWeb in partnership with MedicinMan - follow 3 simple steps:
Go to www.credoweb.in
Create your “Pharma professional” registration
Follow Digital Excellence Pharma Academy page and stay tuned for our webinars for which you will be cordially invited
The Mankind Pharma Story by Dr. Sumit GhoshalAnup Soans
Mankind was established in 1991, almost a decade after the industry leaders of today including Dr.Reddy’s and Sun Pharma, but has grown considerably faster than its contemporaries...
One reason for this is that unlike major drug makers who have a large portfolio of hundreds of products, mankind prefers to concentrate on a much smaller number of high value products. “they don’t bother with smaller products with a potential value of less than Rs.5 crore,” says a long-time industry watcher. thus Health OK, their OTC product, which is a combination of vitamins and nutritional medicines was able to generate Rs.50 crore in revenue within a year of its launch in 2014-15.
This is also the approach adopted by some multinationals like Sanofi, whose CEO Chris Viebacher said, that his company obtained a lion’s share of its revenue from just 15 top selling patented products...
Indian Pharma and Retail Pharmacies - Sales View PollAnup Soans
The Sales View poll concluded with valuable information on several key aspects of the Indian Pharmaceutical field force, especially in the strategies employed by medical sales reps to obtain marketing intelligence. With sales force considered to be a strong pillar of the pharmaceutical industry, gaining pointers on their day-to-day operations, and challenges faced, is indeed an asset in improving the pharma industry.
Such weekly and monthly data analysis by IQVIA and leading pharma KOLs will help you understand market dynamics better. Do participate in our polls and keep up with the latest opinions and trends on IQVIA Sales View.
Healthcare's Future will be Patient ExperienceAnup Soans
With healthcare reform now opening the door to more insured patients, it is not overwhelming what we hear nowadays that market access is dead and patient access is the new prescription for healthcare marketing.
Patient access helps when there is precariousness in the benefits, which will never be fully known until a product is used in the real world and over a period of time.
A patient access centered mindset aims to understand the patient and provider pathways, with the ultimate objective that all those patients who can optimally benefit from a product can have the access to the product.
Instead of a win/lose mindset at the core of market access, patient access tries to create win/win/win solutions that lead to value for patients, companies, and the healthcare system at large.
In such a scenario, several issues that should deal with patient access should be addressed such as:
Patient access as a guiding principle across all functions
Developing a clear and compelling value proposition for each stakeholder group
Creating a formal framework for understanding the impact of decisions on patient access
Getting payer input and advice early on
Enhanced patient satisfaction
Improved communication through shared data
Unethical Practices in Pharma - Interesting Study from Pakistan Anup Soans
This study clarifies the current pharmaceutical drug promotion and prescribing practices in Pakistan. The majority of prescribers and national pharmaceutical firms and to some extent the multinational pharmaceuticals are involved in unethical practices in drug promotion and prescribing. Alarming policies governing the drug promotion and prescribing are required to be implemented by the concerned regulatory authorities to avoid unnecessary harm to the patient’s life and pocket through the unethical drug promotion. The prescribers should not accept any incentives, gifts of financial value from any pharmaceutical companies in return for an increase in prescribing selected brand. On the other hand, pharmaceutical companies must compete in the market on the basis of the drug quality and do not offer any valuable gift and incentives to the prescribers. The interaction between doctors and phar- maceutical firms should be restricted within acceptable boundaries and the authorities must be prepared to play an active role. Strengthening the regulatory machinery and formulating policies in this regard in neces- sary. It is essential that a health care professional such as a pharmacist can play an important role in this process since he/she is an expert in the pharmaceutical field as well as more aware of the outcomes of unethical drug prescribing practices such as polypharmacy and adverse drug reactions.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
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The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
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Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
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Pharma Policy 2017 - Read it in MedicinMan September 2017 Issue
1. CCan you give us an overview of the
draft Pharma Policy? Does it include
devices, diagnostics and disposables
sector as well?
Indian Pharma industry has made
tremendous progress in the last 40
years. Today we have reached a
sizeable sales volume of over 2.1 lac
crores and Indian Pharma’s
contribution to exports is over 1.10 lac
crores. Indian Pharma exports to over
200 countries and has the highest
number of regulated-market approved
facilities that produce medicines at the
lowest prices in the world.
Having said that, there are many areas
that must be addressed, like the drop
in growth from 15 per cent to 8 per
cent per annum, over-dependence on
imported API’s, the need to keep
upgrading to meet global quality
expectations and, most importantly, to
build a sustainable future that meets
the healthcare needs of Indians.
DRAFT PHARMA POLICY:
THE GOOD, THE BAD THE UGLY
Interview with Sunil Attavar
Continued after the Contents page.
September 2017
2. CONTENTS
1. Draft Pharma Policy: The Good, The Bad
and The Ugly………………………………………..1
Interview with Sunil Attavar
2. Career Brand Plan: A Career Stepping
Stone………………………………………………….9
Soham Wagh
3. Succeeding as Country GM at GSK: A
Whitepaper……………………………………….12
Sundar Ramachandran
4. Role of Digital in the Customer Journey
………………………………………..…………………21
Salil Kallianpur
5. Executive Function Disorder ..……………24
Vivek Hattangadi
3. Interview with Sunil Attavar | Draft Pharma Policy: the Good, the Bad the Ugly
3 | MedicinMan September 2017
In the past, policies usually focused on the
issues of price control. Hence there was a
need for an all-encompassing policy to
address the needs of all stakeholders
including the industry and the public.
A separate draft policy for medical devices is
already in circulation and under review, in
consultation with all
stakeholders.
How long has the draft Pharma Policy been in
the making and closely has the pharma
industry been consulted during the process?
I am not sure of the exact duration, but it
has been in the making for a while now and
many of the components like the API policy
and UCPMP have been under discussions
for over five years. The API policy was
studied by the Katoch Committee, which
made several recommendations; some of
these find mention in the draft Pharma
Policy, like the proposal for mega parks.
Many other issues like quality
improvements, introduction of BA/BE
studies, upgradation to WHO standards
have also been discussed for quite some
time. The draft Pharma Policy brings
together all the different components into
one consolidated document.
Indian Pharma has been consulted from
time to time along with other stakeholders
like the regulators, trade, civil society
including doctors, NGOs, the scientific
community and academia. These
consultations have been broad-based and
all views are being taken into account
before the final Pharma Policy is
announced.
Q.3. What are the important goals that the
government seeks to achieve through
the Pharma Policy?
➢ The goals are well articulated in the key
objectives, which are:
➢ Making essential drugs accessible at
affordable prices to the masses.
➢ Providing a long term stable policy
environment for the pharmaceutical
sector.
➢ Making India sufficiently self-reliant in
end-to-end domestic drug
manufacturing.
4. Interview with Sunil Attavar | Draft Pharma Policy: the Good, the Bad the Ugly
4 | MedicinMan September 2017
➢ Ensuring world-class quality of drugs for
domestic consumption and exports.
➢ Creating an environment for R&D to
produce innovative drugs.
What is the industry's response to the
draft Pharma Policy? The good, the not-so-
good and objectionable?
Considering that the draft Pharma Policy has
so many recommendations, there are
varying responses to different issues from
different constituents.
The Good:
1. Focus on Quality and Upgradation of
Manufacturing
Although India enjoys quite an enviable
position in the global pharma industry, the
need to align our quality practices to global
standards and upgrade is something the
industry welcomes. There is a general
consensus that India must upgrade its
Schedule M to global standards, for which
we have all the capabilities. Considering the
huge impact Indian Pharma makes on the
global market, it must have standards that
the world accepts.
Though the transition will be tough, the
government has proposed to extend all the
support by way of financial resources and
also invest in skill development to help the
industry build competencies. The SMEs are
particularly vulnerable in this area and
industry has urged that special support be
extended to them.
2. Skilling
The need to build technical competencies
and quality manpower finds a mention in
the policy which is welcome indeed. We
have suggested that this process be
extensive and accessible to all.
3. Support for API Sector
The API sector is in urgent need of revival.
As a country we stand exposed to grave
strategic risks as a very large portion of
formulations depend on Chinese raw
materials and intermediates. Many critical
drugs are no more being made in India and
hence we need to leapfrog in a haste. The
policy makes a special mention on the
support to be extended to the API sector for
a quick turnaround.
5. 5 | MedicinMan September 2017
The policy makes a special mention on the
support to be extended to the API sector for
a quick turnaround. Many valuable inputs
have been given which I am sure will find a
way to the final policy that will be a great
help.
4. UCPMP and Cap on Trade Margins
We are aware that the many of the current
marketing practices leave a lot to be
desired. Indian Pharma has welcomed the
proposal to make UCPMP statutory. From
KDPMA we have suggested that the scope
be extended to nutraceuticals,
cosmeceuticals and AYUSH so that possible
loopholes are plugged. The penal actions
must be a deterrent enough but not a tool
for unnecessary harassment.
Implementation of UCPMP coupled with a
cap on trade margins will be a great positive
for ethical marketing companies and will
also help control the price of medicines.
5. Focus on R and D
The draft Pharma Policy proposes many
initiatives and incentives to support
investments in R&D. There is also a push for
bringing academia and industry together for
creating synergy and better allocation of
tasks. This is much a needed and welcome
development.
Proposal to bring all the
regulators/authorities pertaining to the
pharmaceutical industry under one
department and clarity on the DPCO
mechanism
This will help the industry, the regulators
and the government, allowing all health-
related issues to be addressed together
rather than having different ministries and
departments addressing various issues.
Also, with clarity on the DPCO there will be
lesser scope for litigations.
There is a strong suggestion from within the
NPPA to make DPCO a more holistic act and
take it away from the Essential Commodities
Act (branding drugs and health as a
commodity is inappropriate said an officer
at a stakeholders meeting). instead it should
be part of the Affordable Healthcare Act
that includes diagnosis, hospitals and drugs.
Interview with Sunil Attavar | Draft Pharma Policy: the Good, the Bad the Ugly
6. 6 | MedicinMan September 2017
The Not–So–Good
1. Making BE/ BA tests mandatory for
renewals
While the industry appreciates the need to
have BE studies for new launches, many
concerns remain. There is already a
notification to this effect but so far this
could not be enforced since we still are
awaiting clarity on the list of exempted
molecules and the list of marker products
against which the BE study has to be done.
There are not enough centers to conduct
these complex studies and it will take a long
time to put the required infrastructure in
place.
Taking the constraints into consideration,
we have suggested that to begin with BA/BE
to be made mandatory only for all new DCGI
approvals as well as for existing drugs which
have low solubility and low permeability or
if there have been adverse reports for a
particular product. For other categories, in-
vitro dissolution test can be made
mandatory for all drugs including FDCs
which will meet the objective. This will put
in place a process that will only become
more efficient in the coming days.
The Objectionable
1. Third Party Audits
This is very risky considering that inspectors
will have access to all documents and other
data as well as infrastructure. This will lead
to most companies resisting third party
audits as they are unsure of the
confidentiality of data. These inspections
will not have any statutory validity.
2. Proposal of One Company One Drug, One
Brand, One Price
Although we understand that this is done to
stop small trading companies and have
more control on quality, to apply this across
the board will be akin to bombing the city to
kill rats. The proposal will actually restrict
innovation. The MSME sector will be the
most impacted and will face certain closure.
We have made a suggestion that marketing
companies be brought under separate drug
licensing category for better monitoring and
compliance for quality and pricing. Also, the
policy can insist that one-drug-one price be
applied for marketing companies.
Interview with Sunil Attavar | Draft Pharma Policy: the Good, the Bad the Ugly
7. 7 | MedicinMan September 2017
3. Proposal to Phase Out Loan Licensing
Although there is no confirmed data, it is
estimated that over 70 per cent of MNC
products and 50 per cent of domestic
company products are manufactured under
loan licensing or P2P. This excludes
thousands of smaller companies who
market products in small geographic
pockets and propaganda cum distribution
companies (PCDs). Stopping this will
severely impact the availability of drugs.
Even with a timeline to phase it out, it is
going to require some serious planning and
investment. Shifting products or setting up
new facilities and completing all the
required approvals, documentations, trials
and validations for such a large number of
products will require a time frame of 5 to 10
years and investments of thousands of
crores.
To allay the fear of quality we have
suggested that the Drugs and Cosmetics Act
be amended to make the brand owner
equally responsible for quality. This will
prevent fly-by-night companies from
entering the market.
In fact, loan license and P2P must be
encouraged with a pragmatic policy of Make
in India and encourage entrepreneurship
among young pharmacists. Lack of
entrepreneurship in the pharmaceutical
sector will lead to problems of self-
sufficiency of medicines. P2P and loan
license has always attracted pharmacy
graduate entrepreneurs to set up
manufacturing facilities.
4. Proposal to Move to Generics-only Rx
This will be catastrophic for Indian Pharma.
To simply wish away the concept of brands
will mean that no company will be keen to
invest. Pharmaceutical sector will become a
trade dominated commodity business. Good
number of marketing companies will have
to close down. There is evidence to show
that having a product under generic has
neither helped lower the price nor benefit
the patient in any manner. In fact, this will
lead to shutting down of many companies,
which will have the opposite effect of what
is expected.
Interview with Sunil Attavar | Draft Pharma Policy: the Good, the Bad the Ugly
8. 8 | MedicinMan September 2017
We believe that the reason for this proposal
is the growing concern that the prices of
branded medicines are high due to
allurements given to doctors to prescribe
brands. This concern can be better
addressed by making UCPMP into law.
What Benefits Will Patients Get from the
Pharma Policy When Implemented?
Patients will see some tangible and some
intangible benefits. Since the policy
proposes to expand the scope of price
control, patients can expect price
reductions in more number of products.
UCPMP to curb undue allurement of doctors
and cap on trade margins will have an
indirect benefit in reduction of prices.
The intangible benefits will be a definite
improvement is the quality of products that
they are prescribed. Doctors will have more
confidence in the companies and they can
expect more predictable treatment
outcomes.
Investments on quality facilities, R&D and
skills development will bring in better
products in the future that are more aligned
to the needs of our county and help
employment generation, exports and
Improve Quality of Life for All
We hope that the final policy will address
the concerns that industry has expressed
and will be a path-breaking document that
sets a roadmap for a strong and sustainable
growth of the industry that caters to the
wellbeing of Indian citizens. M
Interview with Sunil Attavar | Draft Pharma Policy: the Good, the Bad the Ugly
Sunil Attavar is CMD of Group
Pharma and President, Karnataka
Drug and Pharmaceutical
Manufacturers Association
9. FFor a new Brand Manager, there
cannot be a better opportunity than
the annual brand planning exercise, to
make their presence felt in the
organization.
If a Brand Manager is able to create a
great annual brand plan in his/her first
year itself, it would be the equivalent
of a batsman hitting a century on
debut in international cricket or a
striker scoring a goal within the first 5
minutes of his first football World Cup
match.
Apart from potentially creating great
value for the organization by preparing
a great brand plan which capitalizes on
the market opportunities, a Brand
Manager has so much to gain from
their first annual brand planning
exercise like
1. Understanding each and every
aspect of the brand and it's operating
environment
Annual Brand Plan: A
Career Stepping Stone
Soham Wagh
9 | MedicinMan September 2017
10. Soham Wagh | Annual Brand Plan: A Career Stepping Stone
10 | MedicinMan September 2017
2. Developing a clear understanding of the
competition
3. Building strong network with all internal
stakeholders involved in the brand planning
process
4. Getting attention of senior stakeholders
Here are some simple tips that can help
Brand Managers to come out as winners in
their first annual brand planning exercise
1. Understand the templates
Most organizations have set templates for
the annual brand and they are released to
Brand Managers well in advance for
ensuring robust preparation. Getting
familiarized with the templates early on is
extremely critical. Any doubts should be
clarified with the immediate boss or the
Strategic Marketing/Business Excellence
team responsible for the annual brand
planning templates.
2. Be proactive in data analysis
Being proactive on analyzing all data from
primary and secondary sources is extremely
critical. Jot down all the parameters that are
important for creating a solid understanding
of the internal and external scenario and
cull out all necessary data to answer critical
questions. Ensure that no data
collection/analysis is left for the last minute
because that will lead to a lot of anxiety and
heart burn.
3. Look at existing best practices
It is very easy to get drowned in our own
work and not pay attention to best practices
around us. Reach out to experienced Brand
Managers who are leading successful
brands. Understand from them what makes
their brands click and do’s and don’t’s for
the annual brand planning process.
4. Anticipate stakeholder questions
Anticipating stakeholder questions is useful
to tackle them. Once a clear understanding
of what are the key brand challenges, what
are shifting trends in the industry and what
is the competition up to, is obtained,
addressing these questions becomes
relatively easy.
11. Soham Wagh | Annual Brand Plan: A Career Stepping Stone
11 | MedicinMan September 2017
5. Think beyond the template
Although templates are important it is
equally important to go beyond the
templates to support some important
choices you wish to pursue but are not easy
to explain through the set template.
6. Version control
The annual brand will be revised and
changed a million times before its final sign-
off. It is very easy to get confused with
which version is the latest and captures all
the changes/corrections suggested at
various stages by important stakeholders.
Maintain a separate folder with proper
information on which version is latest one.
7. Language and semantics
Often people tend to notice small mistakes
in spellings and grammar rather than other
important aspects. No matter how silly this
sounds but ensure no spelling mistakes
creep into the annual brand plan. If it helps
volunteer to spell check a colleague’s plan in
return of he/she doing the same for your
plan.
8. Practice
No matter how great a plan you have
prepared unless you deliver it in an
absolutely flawless manner on the day of
reckoning all the efforts put in through
months of preparation would go to waste.
Practice the delivery in front of the mirror,
practice in front of a trusted colleague,
friend or family to get your act right.
First impression might not be the last
impression but they are definitely lasting
impressions. Your first annual brand
planning session is your rite of passage from
a rookie marketer to a marketer who will
shape the future of the brand. M
Soham Wagh is a Pharmaceutical Marketing
professional based out of India. Soham likes
to write about easy to implement self-
improvement tips and other contemporary
issues affecting business. The opinions
expressed here are his own and does not
reflect that of any other organization or
individual.
12. UUniform generalisations about the GM
role are unhelpful. As there is no one
type of a country, there is no one type
of a country GM. The commercial
context of the country and the internal
dynamics determine the GM archetype
required for success.
Transitioning into the GM role can be
complex and it is easy to get lost in the
fuzziness of leadership or the link
between leadership and business
strategy. There is scaffolding that GSK
has put in place to support this
transition through a structured GM
onboarding track. It’s not uncommon
though for leaders to feel lonely and
lost in the sea of options available to
them. The choices that leaders make
during this important passage of play
can have a disproportionate impact on
the people they lead and the markets
they serve.
Succeeding as Country GM
at GSK: A Whitepaper
Sundar Ramachandran
12 | MedicinMan September 2017
13. Sundar Ramachandran | Succeeding as Country GM at GSK: A Whitepaper
13 | MedicinMan September 2017
Based on my discussions, five key themes
emerged that GMs can pivot around. The
experience, exposure and education lens
referred to as the 70:20:10 framework
provides an overarching structure to build
these capabilities.
1. Navigating the VUCA environment –
Navigating a volatile, uncertain, chaotic and
ambiguous environment
2. Balancing Values & Value –
Being an ambassador of GSK values and
delivering sustainable commercial results
3. Managing the local commercial dynamics –
Developing a visceral understanding of the
market
4. Leading in a matrix and the global - local
mix –
Developing an enterprise view and
influencing without authority
5. Leadership brand & talent ambassador –
GMs role as an actor and the architect
---
1. Navigating the VUCA environment
GMs need to have an informed view of the
macro environment which is shaped by the
pace of change in technology, evolving
commercial models and socio-political
nuances. They have to navigate through the
volatile, uncertain, chaotic and ambiguous
nature of the markets in which we operate.
Their ability to deal with the unknown, pick
up early signals, keep pace with the new
trends and make strategic choices about
investment options is what makes the GM
role valuable to the enterprise.
Source: HBR
14. Sundar Ramachandran | Succeeding as Country GM at GSK: A Whitepaper
14 | MedicinMan September 2017
Most interviewees suggested that this
capability can be built by staying invested in
new developments, being proactive in
gathering insights by reading, following
thought leaders and participating in industry
forums and think tanks.
GM Speak:
“Executives who have an experiential
understanding of what it takes to sense
trends, respond and learn will be better
prepared for VUCA. Driving digital
transformation in the market is one example
of what’s expected from the GMs. This is not
just about technology but fundamental
shifts in how people communicate, learn and
engage. Multi country experiences, above
country roles and exposure to other
industries builds the capability of picking up
early signals” - Colleen Schuller (VP & Global
Head of Selling Excellence)
“Aspiring GMs must be deliberate about
taking big risks and learning from failures.
Getting involved in enterprise wide cross
functional projects outside your area of
expertise builds this capability. It also builds
the ability to handle stress and provides a
reservoir that GMs can fall back on during
uncertain times” - Omar Luqmaan-Harris
(General Manager - Indonesia)
Recommendations
➢ Get involved with the start-up ecosystem
in your country to spot early trends.
Establish a reverse mentoring
relationship with founders of a few
healthcare start-ups. You can offer them
guidance on managerial and leadership
issues where they lack bandwidth and in
return pick up insights on future trends.
➢ Participate in industry associations and
conferences and develop an external-in
viewpoint
2. Balancing Values & Value
GMs have to establish a balance between
being an ambassador of our corporate
values (integrity, respect for people,
transparency and patient focus) and
delivering sustainable commercial results.
15. Sundar Ramachandran | Succeeding as Country GM at GSK: A Whitepaper
15 | MedicinMan September 2017
It also requires the commercial savviness to
identify opportunities and deliver
sustainable results. GMs must be explicit
about our focus on performance and drive
the self-belief in teams about winning in the
market the right way. This capability can be
built by studying our values to the point of
being able to be explicit and articulate
about them.
My interviewees suggested that one way of
achieving this is to link the commercial wins
in the market with specific values as
appropriate. These stories can then be
scaled across the organisation to drive a
tangible understanding of delivering
commercial success while living the GSK
values. Leveraging our history and sharing
examples of how deviating from our values
has adversely impacted our reputation is
also one narrative that GMs can use. A
balanced approach is key to our reputation
as an enterprise and GMs must take
accountability for this.
GM Speak:
“The GM must walk the talk on values.
Owning up to your part in the failure
engenders you with humility and
vulnerability - key attributes of a trust
building leader. Your teams will also learn it
is okay to acknowledge and learn from
failure and you can build a culture of failing
fast and learning”. Balancing between
corporate values and outcomes requires
GMs to be practically patient meaning that
you understand that some things will take
time to work out due to practical constraints
of time, resources, and capability. This does
not mean you remain in a ‘wait and see’
mode - remember that ‘hope is not a
strategy’. Check in on the progress of your
plans early and often and keep calibrating
as required.” – K. Hariram (Retired
Managing Director - Galderma Pharma &
CEO coach)
Recommendations
➢ Be explicit about commercial outcomes
and leverage values as a vehicle to get
there. Leverage diagnostic reports like
value assurance surveys to understand
the voice of the organisation
16. Sundar Ramachandran | Succeeding as Country GM at GSK: A Whitepaper
16 | MedicinMan September 2017
➢ Engage in storytelling to share how
commercial success ties up with
enterprise values. Embed values in your
overall narrative and messages to the
wider organisation
3. Managing local commercial
dynamics
Execution excellence is a principle areas of
focus for GMs. This requires an
understanding of the competitive
landscape, local insights, superior
management of channels and marketing
activation. It was no surprise that the typical
career path to the GM role included roles in
sales and marketing particularly at the level
of managing strategic brands. The need to
move from a pure play selling mind-set to
co-creating a long term business plan also
emerged as a key capability.
Most interviewees acknowledged that the
period of assessing, listening and learning
ends sooner than expected and action is
expected at the end of it. A structured 30-
60-90-day plan provides the overarching
structure to navigate through this phase.
GMs must start with a deep dive into the
P&L and work outwards from that. This
provides clear insights into the operating
model, productivity, team performance and
enables them to establish commercial goals.
The ability to influence the external
environment which includes the
government, industry associations, channel
partners and trade was recognised as a key
capability. Broad based exposure that cuts
through key functions like GMS, Finance and
HR was also recognised as a success factor.
Interviewees felt that capabilities such as
establishing feedback systems, governance
structure, hiring key talent and building a
top performing team outweigh any in-depth
technical knowledge that the incumbent
may bring to the role. The consideration set
keeps changing and the decision making
process is complex as a GM. The success
factor is to keep your head down, listen well
and keep learning.
17. Sundar Ramachandran | Succeeding as Country GM at GSK: A Whitepaper
17 | MedicinMan September 2017
GM Speak:
“Practice decision making and develop a
mental model to evaluate choices. As a GM,
every conversation you have is a potential
decision point. Aspiring GMs must build the
ability to make decisions with a limited
consideration set or data points. This can be
learnt by getting involved in high stake
projects as the sponsor or lead. Listening
more than speaking and being data driven
are also handy tools to navigate in a new
environment. Learn the rules of alignment
and be pragmatic with your expectations.
The 70:20:10 framework for alignment can
be useful.
➢ 70% - You must adapt to the new market
& people
➢ 20% - The teams must adapt to your style
of functioning
➢ 10% - Nobody will adapt. Accept it and
keep moving ahead”
Sridhar Venkatesh (GM - CARICAM)
“Most GMs have a bias for action and this
can sometimes be at the risk of not spending
enough time in the listening to understand
mode before planning initiatives. Spending
significant amount of time with the outgoing
GM and the local HR head can accelerate
the understanding of the market”. –
Gurprriet Siingh (Senior Partner - Korn Ferry
Hay Group & CEO coach)
Recommendations
➢ Join the expat CEO community in the
country and use it as a soundboard to
pick up local nuances. Chalk out specific
chunks of time each week for market
visits to develop a visceral
understanding. Read secondary research
and market reports to test your
hypothesis
➢ Identify and deliver quick short term
commercial wins as they are vital to
bootstrap investments and commitment
from the global organisation
4. Leading in a Matrix and the Global -
Local mix
Mastering the matrix and enterprise
thinking are capabilities that aspiring GMs
must build early in their journeys.
18. Sundar Ramachandran | Succeeding as Country GM at GSK: A Whitepaper
18 | MedicinMan September 2017
GMs must also build the capability to
establish an alignment with the regional and
global strategy.
The GM is also expected to provide a strong
voice and shape the global agenda by
mining into local insights. This requires
transition from a short tem focused – ‘can
we get this done’ business strategy
approach to a ‘Is it profitable in the long
run’ enterprise strategy approach.
GM Speak:
“Invest in building global relationships and
keep these networks active as leverage
happens over a period of time. Broad based
relationships within the enterprise builds an
appreciation for global platforms,
capabilities, resources & tools. This in
combination with the GMs willingness to
pilot new ideas builds a competitive
advantage.” – Bhushan Akshikar (GM -
Nigeria)
“You have to do it all by yourself is a
misconception. GMs have the hotline to all
key corporate functions and must leverage
this access. Local innovation and creativity
can be blended with global resources and
scale. There is also a tendency in new GMs
to either be an all-out visionary or an all-out
execution champion. There is a middle path
that mitigates this risk of focusing too
broadly or focusing too narrowly.” – Omar
Luqmaan-Harris (General Manager –
Indonesia)
Recommendations
➢ Develop an enterprise view of the
business by working on global projects
early in the journey. Avoid the ‘not
invented here’ syndrome
➢ Leverage the global scale to your
advantage. Be thoughtful and deliberate
about networking as it can provide the
scaffolding required at critical junctures
5. Leadership brand and GM as the
talent ambassador
The GM must think of their role across two
spectrums of being an actor and architect.
The actor refers to the leadership brand of
the GM and that they are always on stage.
19. Sundar Ramachandran | Succeeding as Country GM at GSK: A Whitepaper
19 | MedicinMan September 2017
Building a strong team is, by far, the biggest
imperative for the country GM. In addition
to delivering local results, a strong team
earns the confidence of the global
enterprise, ensures its commitment and
sets off a spiral of success. GMs role as the
torch bearer of the leadership and talent
development activities was a common
theme that resonated with my interviewees.
GMs must also build capabilities to establish
robust talent review processes, champion
diversity, improve the depth and the quality
of talent pipeline and position the local
entity as a great place to work.
Doing a detailed talent review in
partnership with the outgoing GM and HR
Head at the pre joining stage is one way of
getting a head start. This includes but not
limited to looking at talent profiles,
assessment results, career tracks & journeys
of key talent, engagement survey results
and also a macro understanding of the
talent market in that country.
Interviewees also highlighted the need for
the GM to establish their personal
leadership brand that clearly communicates
what they stand for. This is especially
important in clutter of social media and an
inter connected world.
GM Speak:
“Your leadership brand can help you
broaden and deepen your impact. Managing
it is true way of being authentic and an
agent of change. Speaking opportunities at
industry forums, conferences and writing for
trade magazines are all tactical ways of
building this capability for aspiring and new
GMs”. – Ronald Sequeira (Country HR Head -
India)
“Authenticity is key to leadership success
and leaders are being evaluated 24/7. Being
an authentic leader is the only sustainable
advantage. Identification and being
deliberate about building this leadership
brand takes self-awareness and time.
Aspiring GMs must start seeking
professional help from executive coaches in
the early stages to this effect”. – Ransom
Dsouza (VP – Communications &
Government Affairs, South Asia)
20. Sundar Ramachandran | Succeeding as Country GM at GSK: A Whitepaper
20 | MedicinMan September 2017
Recommendations
➢ Leaders are both actors and architects.
Consider speaking at conferences and
writing for trade publications
➢ Do a detailed talent review in partnership
with the outgoing GM and HRBL at the pre
joining stage. Study the macro talent
trends of the country by reading industry
reports and discussions with HRBL
In summary
Supporting the GM transition is not about
setting up a training program as part of the
induction schedule rather having a holistic
view of how the new leader is settling in. Are
they focusing on the right strategic questions?
Is the team buying into the new leadership?
Are they establishing relationships with key
stakeholders and adjusting well to the new
culture?
What is interesting is that with a few
exceptions, most transition support practices
for new GMs are fairly simple, low cost, and
low tech. This is not a one person or one
function responsibility and an all hands on
deck approach involving the regional
president, HR business leader, executive
coaches and global L&D is required to
program manage this successfully.
GM Speak:
“Transitions are not an HR problem, it’s a
multi-dimensional business problem and how
quickly the new leader ramps up, has a direct
impact on P&L. New leaders can sometime
feel like a dropped food packet in a famine
situation. If adequate attention is not paid,
the new executive can get consumed by the
here & now. Hiring well is a good start but
well begun is only half done.” – Deepak
Jayaraman (CEO - Transition Insight. ex Egon
Zehnder consultant) M
Sunder Ramachandran is GM - Training
(Commercial Excellence), India Rx at GSK
21. RRecently I decided to buy a laptop. As I
looked around for the right one, I
realized how little I knew about
hardware. Having always used a
company-provided one, it was one of
the things I had never bothered to
educate myself on.
As I always do for most things that I
know nothing about, I spoke to friends.
From what they told me, I did a lot of
research online. Armed with
information of an ideal laptop, I
decided to “look and feel”. I headed off
to an electronics store and spent the
better part of an hour ‘testing’ a few
models with the help of the friendly
salesman, before I bought the one I
wanted. Do most of us shop this way?
Maybe!
As you see, in my ‘purchase journey’
the human element came in just once
– to seal the deal. With so much
information available online, I had
already made up my mind before I
went into a store and bought what I
wanted to. This was a case of laptops
and dummies, but is this very different
in the case of drugs and doctors?
Role of Digital in the
Customer Journey
Salil Kallianpur
21 | MedicinMan September 2017
22. Salil Kallianpur | Role of Digital in the Customer Journey
22 | MedicinMan September 2017
My personal opinion is that in any selling
process, a human element is never
obsolete, but the effectiveness of that
element is maximized when it is introduced
at the most appropriate moment in the
‘customer journey’.
It is quite well known that in the new era,
70% of the buying decision is made before
the first contact with a supplier is made. By
the time I walked into the electronics store,
I knew which laptop I wanted to buy, its
specifications, its size, color and add-ons. I
walked into that store just to see how that
laptop actually looked and to understand
the deals that the store would offer on my
purchase. The salesman at the store already
had a ready and willing customer and his
sale was efficient and quick even though I
made a big show of looking and evaluating
other options. The actual amount of time he
spent on making the deal was not more
than 15 minutes of that hour.
Such efficiency is needed in pharma sales as
well since the rep model is currently under
stringent evaluation. Companies seeking
operational efficiency are critically analyzing
all major costs and are looking for
alternatives. In such a scenario, instead of
considering a ‘no-rep’ model, companies
should consider a ‘low-rep’ model. This
means downsizing a bulging force to just the
optimal number of people needed to quickly
and efficiently close deals. An example is
illustrated below:
23. Salil Kallianpur | Role of Digital in the Customer Journey
23 | MedicinMan September 2017
As companies build websites, apps, videos
and other digital content, is this a ‘customer
journey’ that they have at the back of their
minds? Are they willing to prime a customer
as much as they can using their formidable
online resources and connect a medical rep
as the final point of contact to seal the deal?
If this is how it can be done, how would the
medical rep’s job evolve? What kind of
training would such sales forces require?
Of course, this isn’t an easy process. Moving
away from a decades-old mindset of
building armies of medical reps isn’t going
to be easy. And to be sure, such models will
probably not be the best in every single
situation. For example, a new product
launch will require a different strategy
compared to a more established brand. The
fact of the matter is, evolving technology
provides superior alternatives to creating
value for customers without having to
compromise traditional sales metrics.
I am pretty sure the salesman at the
electronics store was half-relieved that I
knew what I wanted when I walked in. It
saved his time and allowed him to refocus
his energy to other dummies who wanted
laptops. Wouldn’t drug reps and doctors
feel the same way? M
Salil Kallianpur is a pharma veteran having
worked with industry leaders like Novartis,
Pfizer and GSK. He was Executive Vice
President - Classic Brands COE at GSK
24. AAt 38, you were promoted as Deputy
General Manager because of certain
skills you possessed like decision
making, great analytical skills, critical
thinking, ability to comprehend
complex situations and of course many
other vital areas which require you to
discern between a great risk and a
calculative risk.
You were looking forward to become
the General Manager but pressures of
work and the executive lifestyle has
put your health in shambles. You are
now a diabetic, the diastolic blood
pressure is abnormally high, you
neither have time to exercise regularly
nor time to relax or take a holiday.
Perhaps, you are also in a mild state of
anxiety.
Slowly, over a period of time you are
unable to take any decisive actions.
Your emotional intelligence skills have
reached its nadir. Neither your
superiors, nor your peers and
subordinates seem to rely on your
judgment and opinion on important
issues. In short, you have lost your
mojo.
Executive Function
Disorder
Vivek Hattangadi
24 | MedicinMan September 2017
25. Vivek Hattangadi | Executive Function Disorder
25 | MedicinMan September 2017
At 45, your career has stagnated and you
are still the Deputy General Manager. You
go into a state of depression.
What’s wrong?
This is a typical case of Executive
Dysfunction or Executive Function Disorder.
Executive Function – What is it?
To give an example, take an Air Traffic
Controller at a busy airport. He safely
manages the arrivals and departures of
many aircraft on multiple runways. He
organizes and expedites the flow of air
traffic, and provides information and other
support and logistic for pilots.
Similarly, your brain too needs skills to
comprehend, analyze, filter distractions,
prioritize tasks, set and achieve goals, and
control impulses. Psychologists define
Executive Functions as a term to describe
the many tasks our brains perform that are
necessary to think, act, and solve problems.
Executive Functions enable you to plan,
comprehend, prioritize, decide, focus
attention, remember instructions, and
juggle multiple tasks successfully. And these
are the skill are sets required in ambitious
young upwardly mobile adults.
Science has shown that the hippocampus in
the brain is the seat of cognitive functions,
including Executive Functions. The
hippocampus is under slow attack when a
person is past 35 of age.
When you have lifestyle disease or have
anxiety and depression, β-amyloid plaque
formation is accelerated. This slowly but
steadily begin destroying synapses before it
clumps into plaques and eventually leads to
nerve cell death. The volume of
hippocampus shrinks (called hippocampal
decay). (See Fig 1)
Can this process be reversed?
No.
Can it be controlled and harnessed?
Yes. The volume can be preserved and
protected if you give something which can
prevent the β-amyloid plaque formation in
hippocampus.
26. Vivek Hattangadi | Executive Function Disorder
26 | MedicinMan September 2017
How do you know if you have a deficit in
Executive Functions? Doctors can help you
know if you have Executive Function
Disorder with the help of a tool called
Barkley Deficit in Executive Function Scale
(BDEFS).
Is the management of Executive Dysfunction
elusive? Medical science is making great
progress and surely scientists may be able
to find a solution.
But till then, live a healthy lifestyle – avoid
garbage food, exercise regularly. Work on
your Emotional Intelligence. Your dreams of
becoming the next CEO in your organization
can be fulfilled.
Left-hand: Normal Neuron – Right-hand: β-amyloid plaques
Vivek Hattangadi is a
Consultant in Pharma
Brand Management and
Sales Training at The
Enablers.
He is also visiting faculty at CIPM
Calcutta (Vidyasagar University)
for their MBA course in Pharmaceutical
Management.
vivekhattangadi@theenablers.org