The document discusses the choice facing the United States between prioritizing trade with North America or Asia in the 21st century. It argues that focusing on deepening economic integration with Canada and Mexico through initiatives like infrastructure investment would do more to stimulate the US economy and create jobs than the Trans-Pacific Partnership. Strengthening North America as a economic bloc would also give the region more bargaining power in negotiations with Asia. The author believes North America should be the top trade priority over the TPP.