Hewkahdjsksmamamakdyriwowueuwiwosmhdhdgajqieruwokdeskdiensmsksifidmdjeueyeyeueieyrurirkxnnzvatweuridjdyrudhdjdjskskwiruekeknnxxnxnxnxnxnxnxnxnxnxnxnxnxnxnxnx

1. New Harvard Peristaltic Pumps
R. Pelletier, September 2012

2. What is a Peristaltic Pump
• Positive displacement pump
• Fluid is contained within a flexible tube
fitted inside a circular pump casing
• A rotor with a number of "rollers",
attached to the external circumference
compresses the flexible tube.
• As the rotor turns, the part of tube
under compression is pinched closed
forcing the fluid to be pumped to move
through the tube.
• Flow Rate depends on tubing I.D.,
length of tubing, and motor rpm.

3. Peristaltic vs. Syringe Pumps
Parameter Syringe Pump Peristaltic Pump
Accuracy High (<0.25%) Low (>1%)
Precision High Variable
Reliability High High
Needs Refill Yes (unless using valves) No
Pressure High (>1,000 psi) Low (<50 psi)
Flow Type Pulseless Pulsatile
Multichannel Yes Yes
Market Size <$50 M/year >$200 M/year
Year Developed 1950's 1880's

4. Peristaltic Markets
• Academic Life Science
• Pharmaceutical & Biotech
• Food & Flavors
• Chemical Industry
• Semiconductor
Near Term HA targets are Life Science and Pharmaceutical
Sectors
Fluid Transfer & Volume/Time Dispensing in:

5. Application Areas
• Large Volume Infusion
• Sample Preparation
• Recirculating Baths
• Organ/Tissue Perfusion
• Dosing/Filling
• Dispensing Cell Culture Media
• Large Volume Dispensing

6. The Harvard Peristaltic Pump
• Unique Architecture – Remote configuration
• Interchangeable motor/heads – Versatility and wide range
of flow rates
• Digital Control - accuracy
• Space Saving – use in incubators and hoods

7. Flow Rate Ranges - 1
• P-70 Motor/Head – Low Flow perfusion and small volume
dispensing
• 5 Fluid Channels
• 8 Rollers (smooth flow)
• Flow from 0.001 to 70 mL/min per channel
• Uses 3 collar tubing (0.13-2.79 mm ID)

8. Flow Rate Ranges - 2
• P-230/Head – Organ/Tissue/Cellular Perfusion
• 4 Fluid Channels
• 8 Rollers (smooth flow)
• Flow from 0.001 to 230 mL/min per channel
• Uses 2 collar tubing (0.13-3.17 mm ID)

9. Flow Rate Ranges - 3
• P-1500/Head – Bulk Fluid Transfer/Dispensing
• 1 Fluid Channel
• 4 Rollers
• Flow from 0.01 to 1,500 mL/min
• Uses straight tubing (0.8-8.0 mm ID)

10. Controller Features
• HA Touch Pad User Interface
• Ease of Use
• Tubing Library
• Calibration
• Timed or Volume Dispense/Delivery
• Flow Ramps
• Method Storage
• Combine channels function for setting total flow
• Constant Pressure Mode

11. Quick Start Menu

12. Pump Settings
Settings allow for interchangeable drives/heads on one control unit

13. Tubing Selection
Built in library allows for the
selection of HA supplied tubing or
tubing of the customer’s choice
Icon indicates combined number of
channels for flow rate. For example, P-
70 with 2 channels selected will have
maximum flow of 140 mL/min

14. Timed or Volume Dispense
Set Dispense by time or Volume

15. Method Profiles
Methods may be linked as well as stored
Advanced Options allow for methods to be tied
to I/O events and time delays

16. Calibration
Pump calibration may be for single channel, or combined
flow from multiple channels

17. Run Screen
Method Preview
Method when running showing status

18. Advanced Options & I/O Capabilities
Allow for timed start/stop
Remote start
Signal in or out at start/during/end of
run
I/O Ports – Back Panel

19. Competition - 2 General Types of Peristaltic Pumps
• Type 1 - Analog (similar to HA MP-II)
• Sell for $500 - $1,200
• Older design electronics
• Flow rates are approximate
• No modern features
• Difficult to calibrate
• Limited I/O capability

20. Competition
• Type 2
• Digital – Sell for $1,500 to $4,000
• Advanced electronics
• Allow for calibration and direct setting of flow

21. Competition
• Main Competitors – Digital
• Cole Parmer
• Ismatec/Reglo
• Watson Marlow
• Wheaton Scientific

22. Competition
• Cole Parmer mainly 1-2 channel systems
• Ismatec/Reglo multichannel systems, but low level
electronics. Sold through distributors.
• Watson Marlow mainly OEM supplier of pump heads.
Wheaton uses WM heads.

23. Competition
• Compete on capabilities and application –
• Start with number of channels and flow rates
• Digital capabilities
• Product Configuration options
Know the competitive product and be sure you are making a valid
comparison.

24. Competition
• HA Pricing is competitive
• For P-70, HA ILP=$2,990, Competitive range is $2,900-
$3,200.
• For P-230, HA ILP=$3,162, Competitive range is $3,000-
$3,300
• For P-1500, HA ILP=$2,474, Competitive Range is
$2,200-$2600

25. Not Direct Competition - low capability and low price
HA MP-II
Reglo Analog Ismatec Ecoline
Masterflex CL Series
Masterflex IP Series

26. Competition - Direct
Ismatec Digital Drive Ismatec Compact Digital
Masterflex Digital Drive
Masterflex LS Series Wheaton Omispense/Unispense

27. Accessories
• Optimized tubing sets available for all HA Models
• Customers can use their own tubing
• Tubing sales can be a repeat business opportunity

28. HA Marketing Activities
• Shipments to begin in November
• Brochure and web site promotion/eBlast in October
• New Pump Catalog with Peristaltics in October
• Exhibit at Neuroscience meeting in October
• Demo pricing of 50% from ILP for distributors

29. Distributor Activities
• Prepare web site content
• Identify local beta users
• Plan promotional activities

30. New HA Peristaltics
PN Description ILP
70-7000 Complete with P-70 Head $ 2,990
70-7001 Complete with P-230 Head $ 3,162
70-7002 Complete with P-1500 Head $ 2,472
70-7003 P-70 Head/Motor Only $ 2,070
70-7004 P-230 Head/Motor Only $ 2,185
70-7005 P-1500 Head/Motor Only $ 1,725
70-7006 Controller only $ 1,092